SMT201500328B - Trattamento di leucemia linfoblastica acuta - Google Patents
Trattamento di leucemia linfoblastica acutaInfo
- Publication number
- SMT201500328B SMT201500328B SM201500328T SM201500328T SMT201500328B SM T201500328 B SMT201500328 B SM T201500328B SM 201500328 T SM201500328 T SM 201500328T SM 201500328 T SM201500328 T SM 201500328T SM T201500328 B SMT201500328 B SM T201500328B
- Authority
- SM
- San Marino
- Prior art keywords
- lymphoblastic leukemia
- acute lymphoblastic
- leukemia treatment
- treatment
- acute
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11232308P | 2008-11-07 | 2008-11-07 | |
| US18329109P | 2009-06-02 | 2009-06-02 | |
| PCT/EP2009/007970 WO2010052014A1 (en) | 2008-11-07 | 2009-11-06 | Treatment of acute lymphoblastic leukemia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SMT201500328B true SMT201500328B (it) | 2016-02-25 |
Family
ID=41692882
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SM201500328T SMT201500328B (it) | 2008-11-07 | 2015-12-30 | Trattamento di leucemia linfoblastica acuta |
Country Status (27)
| Country | Link |
|---|---|
| US (3) | US20130323247A1 (it) |
| EP (2) | EP2982696B1 (it) |
| JP (2) | JP5647132B2 (it) |
| KR (1) | KR101695327B1 (it) |
| CN (2) | CN107184977A (it) |
| AU (4) | AU2009313040B2 (it) |
| BR (1) | BRPI0921482B1 (it) |
| CA (1) | CA2742249C (it) |
| CY (2) | CY1117033T1 (it) |
| DK (2) | DK2342227T3 (it) |
| ES (2) | ES2558434T3 (it) |
| HK (2) | HK1158668A1 (it) |
| HR (2) | HRP20151168T1 (it) |
| HU (2) | HUE043326T2 (it) |
| IL (1) | IL212652A (it) |
| LT (1) | LT2982696T (it) |
| ME (2) | ME02363B (it) |
| MX (1) | MX2011002927A (it) |
| NZ (1) | NZ591311A (it) |
| PL (2) | PL2982696T3 (it) |
| PT (2) | PT2342227E (it) |
| RS (2) | RS54456B1 (it) |
| RU (1) | RU2536940C2 (it) |
| SI (2) | SI2982696T1 (it) |
| SM (1) | SMT201500328B (it) |
| WO (1) | WO2010052014A1 (it) |
| ZA (1) | ZA201103255B (it) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2633594C (en) * | 2005-12-16 | 2021-10-26 | Micromet Ag | Means and methods for the treatment of tumorous diseases |
| LT2982696T (lt) * | 2008-11-07 | 2019-06-10 | Amgen Research (Munich) Gmbh | Ūmios limfoblastinės leukemijos gydymas |
| ME02947B (me) | 2009-10-27 | 2018-04-20 | Amgen Res Munich Gmbh | Režim doziranja kod primjene dvojno specifičnog protutijela cd19xcd3 |
| SG189869A1 (en) * | 2010-10-27 | 2013-06-28 | Amgen Res Munich Gmbh | Means and methods for treating dlbcl |
| CA2816668C (en) * | 2010-11-10 | 2021-03-23 | Amgen Research (Munich) Gmbh | Prevention of adverse effects caused by cd3 specific binding domains |
| KR102147533B1 (ko) * | 2011-04-28 | 2020-08-25 | 암젠 리서치 (뮌헨) 게엠베하 | 잠재적 유해 효과의 위험에 처한 환자에게 cd19xcd3 이중특이적 항체를 투여하기 위한 투여 요법 |
| US8846042B2 (en) | 2011-05-16 | 2014-09-30 | Fabion Pharmaceuticals, Inc. | Multi-specific FAB fusion proteins and methods of use |
| WO2015121383A1 (en) * | 2014-02-12 | 2015-08-20 | Michael Uhlin | Bispecific antibodies for use in stem cell transplantation |
| US9732154B2 (en) * | 2014-02-28 | 2017-08-15 | Janssen Biotech, Inc. | Anti-CD38 antibodies for treatment of acute lymphoblastic leukemia |
| US9603927B2 (en) | 2014-02-28 | 2017-03-28 | Janssen Biotech, Inc. | Combination therapies with anti-CD38 antibodies |
| PL3531133T3 (pl) | 2014-05-30 | 2024-01-29 | Amgen Research (Munich) Gmbh | Stratyfikacja ryzyka u pacjentów z ostrą białaczką limfoblastyczną z prekursorów b |
| MY192918A (en) | 2014-09-09 | 2022-09-15 | Janssen Biotech Inc | Combination therapies with anti-cd38 antibodies |
| EP3227338A4 (en) | 2014-12-04 | 2018-05-16 | Janssen Biotech, Inc. | Anti-cd38 antibodies for treatment of acute myeloid leukemia |
| US20180021331A1 (en) * | 2014-12-30 | 2018-01-25 | University Of Utah Research Foundation | Hdac1,2 inhibitors and methods of using the same |
| AU2016222830B2 (en) | 2015-02-24 | 2021-02-25 | Bioatla Llc | Conditionally active biological proteins |
| EP3466967A1 (en) | 2015-05-18 | 2019-04-10 | TCR2 Therapeutics Inc. | Compositions and methods for tcr reprogramming using fusion proteins |
| AU2016264725B2 (en) | 2015-05-20 | 2021-05-27 | Janssen Biotech, Inc. | Anti-CD38 antibodies for treatment of light chain amyloidosis and other CD38-positive hematological malignancies |
| WO2016184931A1 (en) | 2015-05-20 | 2016-11-24 | Amgen Research (Munich) Gmbh | B-cell depletion as a diagnostic marker |
| JP6816038B2 (ja) | 2015-06-22 | 2021-01-20 | ヤンセン バイオテツク，インコーポレーテツド | 抗ｃｄ３８抗体及びサバイビン阻害剤による血液悪性疾患の併用療法 |
| US20170044265A1 (en) | 2015-06-24 | 2017-02-16 | Janssen Biotech, Inc. | Immune Modulation and Treatment of Solid Tumors with Antibodies that Specifically Bind CD38 |
| CN105154440B (zh) * | 2015-08-14 | 2016-11-30 | 深圳市瀚海基因生物科技有限公司 | 一种基于高通量测序构建白血病微小残留病灶tcr文库的多重pcr引物和方法 |
| MA53356B1 (fr) | 2015-11-03 | 2022-05-31 | Janssen Biotech Inc | Formulations sous-cutanées d'anticorps anti-cd38 et leurs utilisations |
| US10781261B2 (en) | 2015-11-03 | 2020-09-22 | Janssen Biotech, Inc. | Subcutaneous formulations of anti-CD38 antibodies and their uses |
| RU2651776C2 (ru) * | 2015-12-01 | 2018-04-23 | Общество с ограниченной ответственностью "Международный биотехнологический центр "Генериум" ("МБЦ "Генериум") | Биспецифические антитела против cd3*cd19 |
| GB201602974D0 (en) * | 2016-02-19 | 2016-04-06 | Clube Jasper R | Engineered cells & methods (1) |
| CN109476756B (zh) | 2016-03-15 | 2022-05-31 | 埃泰美德(香港)有限公司 | 一种多特异性Fab融合蛋白及其用途 |
| CN109715668A (zh) | 2016-08-02 | 2019-05-03 | T细胞受体治疗公司 | 用于使用融合蛋白进行tcr重编程的组合物和方法 |
| PT3445787T (pt) | 2016-10-07 | 2021-03-15 | Tcr2 Therapeutics Inc | Composições e métodos para reprogramação de recetores de célula t com o uso de proteínas de fusão |
| CN110177803A (zh) * | 2016-11-22 | 2019-08-27 | T细胞受体治疗公司 | 用于使用融合蛋白进行tcr重新编程的组合物和方法 |
| CA3079242A1 (en) | 2017-10-31 | 2019-05-09 | Janssen Biotech, Inc. | Methods of treating high risk multiple myeloma |
| US20210163592A1 (en) * | 2017-12-11 | 2021-06-03 | Amgen Inc | Continuous manufacturing process for bispecific antibody products |
| KR102083481B1 (ko) | 2018-03-22 | 2020-03-02 | 강원대학교산학협력단 | 아연-키토산 나노 입자를 포함한 급성 림프구성 백혈병 치료용 약학조성물 |
| WO2020132810A1 (en) * | 2018-12-24 | 2020-07-02 | Generon (Shanghai) Corporation Ltd. | Multispecific antigen binding proteins capable of binding cd19 and cd3, and use thereof |
| WO2020232247A1 (en) | 2019-05-14 | 2020-11-19 | Provention Bio, Inc. | Methods and compositions for preventing type 1 diabetes |
| EP4118113A1 (en) | 2020-03-12 | 2023-01-18 | Amgen Inc. | Method for treatment and prophylaxis of crs in patients comprising a combination of bispecifc antibodies binding to cds x cancer cell and tnfalpha or il-6 inhibitor |
| WO2022060901A1 (en) | 2020-09-16 | 2022-03-24 | Amgen Inc. | Methods for administering therapeutic doses of bispecific t-cell engaging molecules for the treatment of cancer |
| CA3235228A1 (en) | 2021-10-15 | 2023-04-20 | Amgen Research (Munich) Gmbh | Subcutaneous administration of cd19-binding t cell engagers |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998008875A1 (de) * | 1996-08-28 | 1998-03-05 | Viva Diagnostika Diagnostische Produkte Gmbh | Kombinationspräparationen und ihre verwendung in der immundiagnostik und immuntherapie |
| WO1999054440A1 (en) * | 1998-04-21 | 1999-10-28 | Micromet Gesellschaft Für Biomedizinische Forschung Mbh | CD19xCD3 SPECIFIC POLYPEPTIDES AND USES THEREOF |
| BG65066B1 (bg) * | 1998-04-21 | 2007-01-31 | Micromet Gessellschaft Fur Biomedicinische Forschung Mbh | CD19 x CD3 СПЕЦИФИЧНИ ПОЛИПЕПТИДИ И ТЯХНОТО ИЗПОЛЗВАНЕ |
| EP1629012B1 (en) | 2003-05-31 | 2018-11-28 | Amgen Research (Munich) GmbH | Pharmaceutical compositions comprising bispecific anti-cd3, anti-cd19 antibody constructs for the treatment of b-cell related disorders |
| KR20120125634A (ko) * | 2003-10-16 | 2012-11-16 | 마이크로메트 에이지 | 다중특이적 탈면역화된 ｃｄ3-바인더 |
| CA2633594C (en) * | 2005-12-16 | 2021-10-26 | Micromet Ag | Means and methods for the treatment of tumorous diseases |
| CN101331151A (zh) * | 2005-12-16 | 2008-12-24 | 麦克罗梅特股份公司 | 治疗肿瘤性疾病的方式和方法 |
| WO2008022152A2 (en) * | 2006-08-14 | 2008-02-21 | Xencor, Inc. | Optimized antibodies that target cd19 |
| LT2982696T (lt) * | 2008-11-07 | 2019-06-10 | Amgen Research (Munich) Gmbh | Ūmios limfoblastinės leukemijos gydymas |
| AU2010204554B2 (en) * | 2009-01-19 | 2013-05-30 | Abbvie Inc. | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases |
| KR20110116161A (ko) * | 2009-01-19 | 2011-10-25 | 아보트 러보러터리즈 | 암, 면역 질환 및 자가면역 질환의 치료를 위한 아폽토시스-유도제 |
| US8486933B2 (en) * | 2009-05-27 | 2013-07-16 | Abbvie Inc. | Pyrimidine inhibitors of kinase activity |
| WO2011034934A1 (en) * | 2009-09-20 | 2011-03-24 | Abbott Laboratories | Abt-263 crystalline forms and solvates for use in treating bcl-2 protein related diseases |
| ME02947B (me) * | 2009-10-27 | 2018-04-20 | Amgen Res Munich Gmbh | Režim doziranja kod primjene dvojno specifičnog protutijela cd19xcd3 |
-
2009
- 2009-11-06 LT LTEP15185767.9T patent/LT2982696T/lt unknown
- 2009-11-06 PT PT97604839T patent/PT2342227E/pt unknown
- 2009-11-06 DK DK09760483.9T patent/DK2342227T3/en active
- 2009-11-06 CA CA2742249A patent/CA2742249C/en active Active
- 2009-11-06 ME MEP-2015-181A patent/ME02363B/me unknown
- 2009-11-06 MX MX2011002927A patent/MX2011002927A/es active IP Right Grant
- 2009-11-06 PT PT15185767T patent/PT2982696T/pt unknown
- 2009-11-06 RS RS20150797A patent/RS54456B1/en unknown
- 2009-11-06 DK DK15185767.9T patent/DK2982696T3/da active
- 2009-11-06 ME MEP-2019-146A patent/ME03480B/me unknown
- 2009-11-06 HU HUE15185767A patent/HUE043326T2/hu unknown
- 2009-11-06 CN CN201710366308.1A patent/CN107184977A/zh active Pending
- 2009-11-06 JP JP2011533633A patent/JP5647132B2/ja active Active
- 2009-11-06 AU AU2009313040A patent/AU2009313040B2/en active Active
- 2009-11-06 EP EP15185767.9A patent/EP2982696B1/en active Active
- 2009-11-06 WO PCT/EP2009/007970 patent/WO2010052014A1/en active Application Filing
- 2009-11-06 US US13/127,541 patent/US20130323247A1/en not_active Abandoned
- 2009-11-06 SI SI200931967T patent/SI2982696T1/sl unknown
- 2009-11-06 ES ES09760483.9T patent/ES2558434T3/es active Active
- 2009-11-06 KR KR1020117010641A patent/KR101695327B1/ko active IP Right Grant
- 2009-11-06 NZ NZ591311A patent/NZ591311A/xx unknown
- 2009-11-06 HU HUE09760483A patent/HUE028175T2/en unknown
- 2009-11-06 PL PL15185767T patent/PL2982696T3/pl unknown
- 2009-11-06 ES ES15185767T patent/ES2727585T3/es active Active
- 2009-11-06 CN CN2009801443998A patent/CN102209728A/zh active Pending
- 2009-11-06 SI SI200931306T patent/SI2342227T1/sl unknown
- 2009-11-06 PL PL09760483T patent/PL2342227T3/pl unknown
- 2009-11-06 RS RS20190593A patent/RS58827B1/sr unknown
- 2009-11-06 RU RU2011122819/10A patent/RU2536940C2/ru active
- 2009-11-06 EP EP09760483.9A patent/EP2342227B1/en active Active
- 2009-11-06 BR BRPI0921482-8A patent/BRPI0921482B1/pt active IP Right Grant
-
2011
- 2011-05-03 IL IL212652A patent/IL212652A/en active IP Right Grant
- 2011-05-05 ZA ZA2011/03255A patent/ZA201103255B/en unknown
- 2011-12-07 HK HK11113215.9A patent/HK1158668A1/xx unknown
-
2014
- 2014-11-06 JP JP2014226022A patent/JP5955921B2/ja active Active
-
2015
- 2015-10-06 AU AU2015238784A patent/AU2015238784A1/en not_active Abandoned
- 2015-11-03 HR HRP20151168TT patent/HRP20151168T1/hr unknown
- 2015-12-09 CY CY20151101123T patent/CY1117033T1/el unknown
- 2015-12-30 SM SM201500328T patent/SMT201500328B/it unknown
-
2016
- 2016-07-22 HK HK16108827.4A patent/HK1220705A1/zh unknown
-
2017
- 2017-08-25 AU AU2017219083A patent/AU2017219083B2/en active Active
-
2018
- 2018-11-06 AU AU2018260815A patent/AU2018260815B2/en active Active
- 2018-12-13 US US16/218,797 patent/US11597766B2/en active Active
-
2019
- 2019-05-16 HR HRP20190912TT patent/HRP20190912T1/hr unknown
- 2019-05-17 CY CY20191100527T patent/CY1122366T1/el unknown
-
2023
- 2023-02-03 US US18/164,304 patent/US20240109964A1/en active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SMT201500328B (it) | Trattamento di leucemia linfoblastica acuta | |
| DK2405869T3 (da) | Fedmebehandling | |
| DE502008000295D1 (de) | Nockenwelle | |
| ATE501136T1 (de) | Imidazopyridinone | |
| DK2175851T3 (da) | Biofilmbehandling | |
| ATE514696T1 (de) | Diphenyl-dihydro-imidazopyridinone | |
| BRPI0812803A2 (pt) | Dessalinização | |
| DK2178568T3 (da) | Kontrastmidler | |
| BRPI0811451A2 (pt) | Exopolissacarídeo | |
| DK2195293T3 (da) | Cyclopropylamidderivater | |
| DK2173831T3 (da) | Brøndbehandling | |
| BRPI0811939A2 (pt) | Tiazóis substituídos por heteroarila | |
| DE502007001776D1 (de) | Clipmaschine | |
| BRPI0720224A2 (pt) | Arilpirazóis substituídos | |
| AT505058A3 (de) | Türschliesssystem | |
| FR2914943B1 (fr) | Aube de soufflante | |
| DE502008000740D1 (de) | Rollosystem | |
| LU93092I2 (de) | Alemtuzumab | |
| BRPI0820907A2 (pt) | Processamento de cerdas | |
| BRPI0817439A2 (pt) | gaseificador | |
| DK2089708T3 (da) | Forudsigelige kræft-immunterapi parametre | |
| DE102007047112A8 (de) | Strahlregler | |
| DE112008000061A5 (de) | Riemenscheibe | |
| AT9563U3 (de) | Wirbelsäulenzuggurtung | |
| AT504425B1 (de) | Portioniersteuerung |