BRPI0811939A2 - Tiazóis substituídos por heteroarila - Google Patents

Tiazóis substituídos por heteroarila

Info

Publication number
BRPI0811939A2
BRPI0811939A2 BRPI0811939-2A2A BRPI0811939A BRPI0811939A2 BR PI0811939 A2 BRPI0811939 A2 BR PI0811939A2 BR PI0811939 A BRPI0811939 A BR PI0811939A BR PI0811939 A2 BRPI0811939 A2 BR PI0811939A2
Authority
BR
Brazil
Prior art keywords
thiazois
heteroarily
replaced
replaced thiazois
heteroarily replaced
Prior art date
Application number
BRPI0811939-2A2A
Other languages
English (en)
Inventor
Xiangzhu Wang
Venkat Gadhachanda
Cuixian Liu
Shouming Li
Jesse Quinn
Dawei Chen
Milind Deshpande
Avinash Phadke
Original Assignee
Achillion Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Achillion Pharmaceuticals Inc filed Critical Achillion Pharmaceuticals Inc
Publication of BRPI0811939A2 publication Critical patent/BRPI0811939A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
BRPI0811939-2A2A 2007-05-22 2008-05-22 Tiazóis substituídos por heteroarila BRPI0811939A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93942407P 2007-05-22 2007-05-22
PCT/US2008/006676 WO2008147557A2 (en) 2007-05-22 2008-05-22 Heteroaryl substituted thiazoles and their use as antiviral agents

Publications (1)

Publication Number Publication Date
BRPI0811939A2 true BRPI0811939A2 (pt) 2014-11-25

Family

ID=39739656

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0811939-2A2A BRPI0811939A2 (pt) 2007-05-22 2008-05-22 Tiazóis substituídos por heteroarila

Country Status (12)

Country Link
US (1) US8183263B2 (pt)
EP (1) EP2164846A2 (pt)
JP (1) JP2010528019A (pt)
KR (1) KR20100020484A (pt)
CN (1) CN101801964A (pt)
AU (1) AU2008257158A1 (pt)
BR (1) BRPI0811939A2 (pt)
CA (1) CA2687817A1 (pt)
EA (1) EA200901573A1 (pt)
IL (1) IL202139A0 (pt)
MX (1) MX2009012613A (pt)
WO (1) WO2008147557A2 (pt)

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WO2013063462A2 (en) 2011-10-26 2013-05-02 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Method of treating hcv infection with a small molecule chk2 inhibitor
TWI475016B (zh) * 2012-05-11 2015-03-01 Beijing Beta Pharma Inc 一組提高激酶活性的化合物及其應用
JP2016510047A (ja) * 2013-03-05 2016-04-04 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ Ｈｃｖ−抗ウイルス薬としてのｎ−ヘテロアリール置換アニリン誘導体
EP3259256B1 (en) * 2015-02-17 2022-03-09 Beijing Erai Therapeutics Co., Ltd. Compounds and methods for inducing browning of white adipose tissue
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CN106467501B (zh) * 2015-08-18 2018-10-26 中国医学科学院医药生物技术研究所 新型抗病毒化合物
CN109641874A (zh) 2016-05-10 2019-04-16 C4医药公司 用于靶蛋白降解的c3-碳连接的戊二酰亚胺降解决定子体
WO2017197036A1 (en) 2016-05-10 2017-11-16 C4 Therapeutics, Inc. Spirocyclic degronimers for target protein degradation
CN109562107A (zh) 2016-05-10 2019-04-02 C4医药公司 用于靶蛋白降解的杂环降解决定子体

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Also Published As

Publication number Publication date
EA200901573A1 (ru) 2010-04-30
US20090041720A1 (en) 2009-02-12
WO2008147557A3 (en) 2009-03-05
CN101801964A (zh) 2010-08-11
CA2687817A1 (en) 2008-12-04
KR20100020484A (ko) 2010-02-22
EP2164846A2 (en) 2010-03-24
MX2009012613A (es) 2010-04-21
JP2010528019A (ja) 2010-08-19
IL202139A0 (en) 2010-06-16
WO2008147557A2 (en) 2008-12-04
AU2008257158A1 (en) 2008-12-04
US8183263B2 (en) 2012-05-22

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2329 DE 25-08-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.