JP5647132B2 - 急性リンパ芽球性白血病の治療 - Google Patents

急性リンパ芽球性白血病の治療 Download PDF

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Publication number
JP5647132B2
JP5647132B2 JP2011533633A JP2011533633A JP5647132B2 JP 5647132 B2 JP5647132 B2 JP 5647132B2 JP 2011533633 A JP2011533633 A JP 2011533633A JP 2011533633 A JP2011533633 A JP 2011533633A JP 5647132 B2 JP5647132 B2 JP 5647132B2
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pharmaceutical composition
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JP2012508164A5 (https=
JP2012508164A (ja
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ツグマイヤー，ゲルハルト
デーゲンハルト，エーフェリン
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Amgen Research Munich GmbH
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Micromet GmbH
Amgen Research Munich GmbH
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2011533633A 2008-11-07 2009-11-06 急性リンパ芽球性白血病の治療 Active JP5647132B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US11232308P 2008-11-07 2008-11-07
US61/112,323 2008-11-07
US18329109P 2009-06-02 2009-06-02
US61/183,291 2009-06-02
PCT/EP2009/007970 WO2010052014A1 (en) 2008-11-07 2009-11-06 Treatment of acute lymphoblastic leukemia

Related Child Applications (1)

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JP2014226022A Division JP5955921B2 (ja) 2008-11-07 2014-11-06 急性リンパ芽球性白血病の治療

Publications (3)

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JP2012508164A JP2012508164A (ja) 2012-04-05
JP2012508164A5 JP2012508164A5 (https=) 2013-03-21
JP5647132B2 true JP5647132B2 (ja) 2014-12-24

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JP2011533633A Active JP5647132B2 (ja) 2008-11-07 2009-11-06 急性リンパ芽球性白血病の治療
JP2014226022A Active JP5955921B2 (ja) 2008-11-07 2014-11-06 急性リンパ芽球性白血病の治療

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US (3) US20130323247A1 (https=)
EP (2) EP2982696B1 (https=)
JP (2) JP5647132B2 (https=)
KR (1) KR101695327B1 (https=)
CN (2) CN107184977A (https=)
AU (4) AU2009313040B2 (https=)
BR (1) BRPI0921482B1 (https=)
CA (1) CA2742249C (https=)
CY (2) CY1117033T1 (https=)
DK (2) DK2342227T3 (https=)
ES (2) ES2727585T3 (https=)
HR (2) HRP20151168T1 (https=)
HU (2) HUE043326T2 (https=)
IL (1) IL212652A (https=)
LT (1) LT2982696T (https=)
ME (2) ME02363B (https=)
MX (1) MX2011002927A (https=)
NZ (1) NZ591311A (https=)
PL (2) PL2982696T3 (https=)
PT (2) PT2342227E (https=)
RS (2) RS54456B1 (https=)
RU (1) RU2536940C2 (https=)
SI (2) SI2982696T1 (https=)
SM (2) SMT201900278T1 (https=)
WO (1) WO2010052014A1 (https=)
ZA (1) ZA201103255B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
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JP2015057417A (ja) * 2008-11-07 2015-03-26 アムゲン リサーチ （ミュンヘン） ゲーエムベーハー 急性リンパ芽球性白血病の治療

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PL2982696T3 (pl) 2019-08-30
CY1122366T1 (el) 2021-01-27
PL2342227T3 (pl) 2016-04-29
JP2015057417A (ja) 2015-03-26
DK2342227T3 (en) 2016-02-15
ES2727585T3 (es) 2019-10-17
EP2982696B1 (en) 2019-03-27
IL212652A0 (en) 2011-07-31
RS58827B1 (sr) 2019-07-31
PT2342227E (pt) 2015-11-13
WO2010052014A1 (en) 2010-05-14
AU2018260815A1 (en) 2018-11-22
ES2558434T3 (es) 2016-02-04
SMT201500328B (it) 2016-02-25
HUE043326T2 (hu) 2019-08-28
HK1220705A1 (en) 2017-05-12
HK1158668A1 (en) 2012-07-20
US20240109964A1 (en) 2024-04-04
JP2012508164A (ja) 2012-04-05
MX2011002927A (es) 2011-04-11
BRPI0921482A8 (pt) 2017-07-11
LT2982696T (lt) 2019-06-10
US20130323247A1 (en) 2013-12-05
EP2982696A3 (en) 2016-02-17
RU2011122819A (ru) 2012-12-20
PT2982696T (pt) 2019-06-04
KR101695327B1 (ko) 2017-01-11
CY1117033T1 (el) 2017-04-05
SI2342227T1 (sl) 2015-12-31
CA2742249A1 (en) 2010-05-14
BRPI0921482B1 (pt) 2022-09-20
CN102209728A (zh) 2011-10-05
AU2009313040B2 (en) 2015-07-09
IL212652A (en) 2015-05-31
AU2018260815B2 (en) 2020-03-05
RU2536940C2 (ru) 2014-12-27
HUE028175T2 (en) 2016-12-28
US20190300609A1 (en) 2019-10-03
AU2015238784A1 (en) 2015-10-29
HRP20190912T1 (hr) 2019-07-26
RS54456B1 (sr) 2016-06-30
NZ591311A (en) 2012-10-26
US11597766B2 (en) 2023-03-07
SMT201900278T1 (it) 2019-07-11
AU2017219083B2 (en) 2018-08-09
EP2342227A1 (en) 2011-07-13
AU2009313040A1 (en) 2010-05-14
KR20110091668A (ko) 2011-08-12
EP2982696A2 (en) 2016-02-10
EP2342227B1 (en) 2015-10-07
JP5955921B2 (ja) 2016-07-20
ZA201103255B (en) 2013-12-23
HRP20151168T1 (hr) 2015-12-04
BRPI0921482A2 (pt) 2016-01-12
CN107184977A (zh) 2017-09-22
ME02363B (me) 2016-06-20
CA2742249C (en) 2020-07-21
ME03480B (me) 2020-01-20
SI2982696T1 (sl) 2019-06-28
DK2982696T3 (da) 2019-05-27
AU2017219083A1 (en) 2017-09-14

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