PT2982696T - Tratamento da leucemia linfoblástica aguda - Google Patents

Tratamento da leucemia linfoblástica aguda

Info

Publication number
PT2982696T
PT2982696T PT15185767T PT15185767T PT2982696T PT 2982696 T PT2982696 T PT 2982696T PT 15185767 T PT15185767 T PT 15185767T PT 15185767 T PT15185767 T PT 15185767T PT 2982696 T PT2982696 T PT 2982696T
Authority
PT
Portugal
Prior art keywords
treatment
lymphoblastic leukemia
acute lymphoblastic
acute
leukemia
Prior art date
Application number
PT15185767T
Other languages
English (en)
Portuguese (pt)
Inventor
Zugmaier Gerhard
Degenhard Evelyn
Original Assignee
Amgen Res Munich Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41692882&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2982696(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Res Munich Gmbh filed Critical Amgen Res Munich Gmbh
Publication of PT2982696T publication Critical patent/PT2982696T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT15185767T 2008-11-07 2009-11-06 Tratamento da leucemia linfoblástica aguda PT2982696T (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11232308P 2008-11-07 2008-11-07
US18329109P 2009-06-02 2009-06-02

Publications (1)

Publication Number Publication Date
PT2982696T true PT2982696T (pt) 2019-06-04

Family

ID=41692882

Family Applications (2)

Application Number Title Priority Date Filing Date
PT15185767T PT2982696T (pt) 2008-11-07 2009-11-06 Tratamento da leucemia linfoblástica aguda
PT97604839T PT2342227E (pt) 2008-11-07 2009-11-06 Tratamento da leucemia linfoblástica aguda

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT97604839T PT2342227E (pt) 2008-11-07 2009-11-06 Tratamento da leucemia linfoblástica aguda

Country Status (26)

Country Link
US (3) US20130323247A1 (https=)
EP (2) EP2982696B1 (https=)
JP (2) JP5647132B2 (https=)
KR (1) KR101695327B1 (https=)
CN (2) CN102209728A (https=)
AU (4) AU2009313040B2 (https=)
BR (1) BRPI0921482B1 (https=)
CA (1) CA2742249C (https=)
CY (2) CY1117033T1 (https=)
DK (2) DK2342227T3 (https=)
ES (2) ES2558434T3 (https=)
HR (2) HRP20151168T1 (https=)
HU (2) HUE043326T2 (https=)
IL (1) IL212652A (https=)
LT (1) LT2982696T (https=)
ME (2) ME02363B (https=)
MX (1) MX2011002927A (https=)
NZ (1) NZ591311A (https=)
PL (2) PL2342227T3 (https=)
PT (2) PT2982696T (https=)
RS (2) RS58827B1 (https=)
RU (1) RU2536940C2 (https=)
SI (2) SI2342227T1 (https=)
SM (2) SMT201900278T1 (https=)
WO (1) WO2010052014A1 (https=)
ZA (1) ZA201103255B (https=)

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RS54655B2 (sr) 2009-10-27 2021-04-29 Amgen Res Munich Gmbh Dozni režim za primenu cd19xcd3 bispecifičnog antitela
CN103459425B (zh) * 2010-10-27 2015-11-25 安进研发（慕尼黑）股份有限公司 用于治疗dlbcl的组合物
EA026075B1 (ru) * 2010-11-10 2017-02-28 Эмджен Рисерч (Мьюник) Гмбх Предотвращение неблагоприятных эффектов, вызванных cd3-специфическими связывающими доменами
KR102345943B1 (ko) * 2011-04-28 2021-12-31 암젠 리서치 (뮌헨) 게엠베하 잠재적 유해 효과의 위험에 처한 환자에게 cd19xcd3 이중특이적 항체를 투여하기 위한 투여 요법
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EA201792546A1 (ru) 2015-05-20 2018-04-30 Янссен Байотек, Инк. Антитела к cd38 для лечения амилоидоза легких цепей и прочих cd38-положительных гематологических злокачественных опухолей
AU2016263464B2 (en) * 2015-05-20 2021-12-23 Amgen Research (Munich) Gmbh B-cell depletion as a diagnostic marker
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CN105154440B (zh) * 2015-08-14 2016-11-30 深圳市瀚海基因生物科技有限公司 一种基于高通量测序构建白血病微小残留病灶tcr文库的多重pcr引物和方法
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CA3004152C (en) 2015-11-03 2024-04-16 Janssen Biotech, Inc. Subcutaneous formulations of anti-cd38 antibodies and their uses
RU2651776C2 (ru) * 2015-12-01 2018-04-23 Общество с ограниченной ответственностью "Международный биотехнологический центр "Генериум" ("МБЦ "Генериум") Биспецифические антитела против cd3*cd19
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EP3430058A4 (en) 2016-03-15 2019-10-23 Generon (Shanghai) Corporation Ltd. MULTISPECIFIC FAB FUSION PROTEINS AND USES THEREOF
US20190233533A1 (en) 2016-06-28 2019-08-01 Umc Utrecht Holding B.V. Treatment Of IgE-Mediated Diseases With Antibodies That Specifically Bind CD38
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JP7291396B2 (ja) * 2016-11-22 2023-06-15 ティーシーアール２ セラピューティクス インク． 融合タンパク質を用いたｔｃｒの再プログラミングのための組成物及び方法
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Also Published As

Publication number Publication date
EP2982696A2 (en) 2016-02-10
KR101695327B1 (ko) 2017-01-11
DK2982696T3 (da) 2019-05-27
SMT201500328B (it) 2016-02-25
SI2982696T1 (sl) 2019-06-28
AU2017219083A1 (en) 2017-09-14
RU2011122819A (ru) 2012-12-20
DK2342227T3 (en) 2016-02-15
US20190300609A1 (en) 2019-10-03
US20130323247A1 (en) 2013-12-05
AU2015238784A1 (en) 2015-10-29
JP5955921B2 (ja) 2016-07-20
JP2015057417A (ja) 2015-03-26
AU2018260815B2 (en) 2020-03-05
WO2010052014A1 (en) 2010-05-14
BRPI0921482A2 (pt) 2016-01-12
ES2558434T3 (es) 2016-02-04
HUE028175T2 (en) 2016-12-28
CN107184977A (zh) 2017-09-22
ZA201103255B (en) 2013-12-23
NZ591311A (en) 2012-10-26
EP2982696B1 (en) 2019-03-27
EP2982696A3 (en) 2016-02-17
CY1122366T1 (el) 2021-01-27
EP2342227B1 (en) 2015-10-07
ES2727585T3 (es) 2019-10-17
ME02363B (me) 2016-06-20
HRP20190912T1 (hr) 2019-07-26
CY1117033T1 (el) 2017-04-05
BRPI0921482B1 (pt) 2022-09-20
US20240109964A1 (en) 2024-04-04
AU2009313040A1 (en) 2010-05-14
AU2009313040B2 (en) 2015-07-09
HK1220705A1 (en) 2017-05-12
HRP20151168T1 (hr) 2015-12-04
MX2011002927A (es) 2011-04-11
LT2982696T (lt) 2019-06-10
HK1158668A1 (en) 2012-07-20
RS54456B1 (sr) 2016-06-30
CN102209728A (zh) 2011-10-05
RS58827B1 (sr) 2019-07-31
PT2342227E (pt) 2015-11-13
IL212652A0 (en) 2011-07-31
US11597766B2 (en) 2023-03-07
EP2342227A1 (en) 2011-07-13
AU2018260815A1 (en) 2018-11-22
CA2742249A1 (en) 2010-05-14
CA2742249C (en) 2020-07-21
KR20110091668A (ko) 2011-08-12
JP2012508164A (ja) 2012-04-05
AU2017219083B2 (en) 2018-08-09
SMT201900278T1 (it) 2019-07-11
ME03480B (me) 2020-01-20
PL2982696T3 (pl) 2019-08-30
BRPI0921482A8 (pt) 2017-07-11
PL2342227T3 (pl) 2016-04-29
SI2342227T1 (sl) 2015-12-31
IL212652A (en) 2015-05-31
JP5647132B2 (ja) 2014-12-24
RU2536940C2 (ru) 2014-12-27
HUE043326T2 (hu) 2019-08-28

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