NZ300654A - Carrier particles and active particles with additive material for use in dry inhalers - Google Patents

Carrier particles and active particles with additive material for use in dry inhalers

Info

Publication number
NZ300654A
NZ300654A NZ300654A NZ30065496A NZ300654A NZ 300654 A NZ300654 A NZ 300654A NZ 300654 A NZ300654 A NZ 300654A NZ 30065496 A NZ30065496 A NZ 30065496A NZ 300654 A NZ300654 A NZ 300654A
Authority
NZ
New Zealand
Prior art keywords
particles
active
additive material
carrier particles
powder
Prior art date
Application number
NZ300654A
Other languages
English (en)
Inventor
John Nicholas Staniforth
Original Assignee
Co Ordinated Drug Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10768844&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NZ300654(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Co Ordinated Drug Dev filed Critical Co Ordinated Drug Dev
Publication of NZ300654A publication Critical patent/NZ300654A/

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7012Compounds having a free or esterified carboxyl group attached, directly or through a carbon chain, to a carbon atom of the saccharide radical, e.g. glucuronic acid, neuraminic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
NZ300654A 1995-01-31 1996-01-31 Carrier particles and active particles with additive material for use in dry inhalers NZ300654A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9501841.2A GB9501841D0 (en) 1995-01-31 1995-01-31 Improvements in and relating to carrier particles for use in dry powder inhalers
GBGB9521937.4A GB9521937D0 (en) 1995-01-31 1995-10-26 Improvementsin and relating to carrier particles for use in dry powder inhailers
PCT/GB1996/000215 WO1996023485A1 (en) 1995-01-31 1996-01-31 Carrier particles for use in dry powder inhalers

Publications (1)

Publication Number Publication Date
NZ300654A true NZ300654A (en) 1999-02-25

Family

ID=10768844

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ300654A NZ300654A (en) 1995-01-31 1996-01-31 Carrier particles and active particles with additive material for use in dry inhalers

Country Status (33)

Country Link
US (5) US6153224A ( )
EP (6) EP1159955A1 ( )
JP (1) JP4042867B2 ( )
KR (1) KR100500694B1 ( )
CN (1) CN1303974C ( )
AT (3) ATE526946T1 ( )
AU (1) AU699131B2 ( )
BG (1) BG101858A ( )
BR (3) BR9612950B1 ( )
CA (1) CA2211874C ( )
CZ (1) CZ294259B6 ( )
DE (2) DE69636961T2 ( )
DK (3) DK0806938T3 ( )
EA (1) EA000352B1 ( )
EE (1) EE9700176A ( )
ES (3) ES2278828T3 ( )
FI (1) FI119676B ( )
GB (2) GB9501841D0 ( )
GE (1) GEP19991687B ( )
HK (1) HK1084897A1 ( )
HU (1) HU229965B1 ( )
IS (1) IS4531A ( )
MX (1) MX9705847A ( )
NO (1) NO324037B1 ( )
NZ (1) NZ300654A ( )
PL (1) PL186757B1 ( )
PT (3) PT1232745E ( )
SI (2) SI1666023T1 ( )
SK (1) SK282630B6 ( )
TR (1) TR199700722T1 ( )
UA (1) UA61051C2 ( )
WO (1) WO1996023485A1 ( )
ZA (1) ZA96721B ( )

Families Citing this family (148)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6743777B1 (en) * 1992-03-19 2004-06-01 Eli Lilly And Company Cyclic peptide antifungal agents and process for preparation thereof
GB9322014D0 (en) * 1993-10-26 1993-12-15 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
GB9501841D0 (en) * 1995-01-31 1995-03-22 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
GB9515182D0 (en) * 1995-07-24 1995-09-20 Co Ordinated Drug Dev Improvements in and relating to powders for use in dry powder inhalers
AUPN661995A0 (en) 1995-11-16 1995-12-07 Memtec America Corporation Electrochemical cell 2
US5874064A (en) * 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
US5871010A (en) * 1996-06-10 1999-02-16 Sarnoff Corporation Inhaler apparatus with modified surfaces for enhanced release of dry powders
US7052678B2 (en) 1997-09-15 2006-05-30 Massachusetts Institute Of Technology Particles for inhalation having sustained release properties
GB9806477D0 (en) 1998-03-26 1998-05-27 Glaxo Group Ltd Improved crystals
US6956021B1 (en) 1998-08-25 2005-10-18 Advanced Inhalation Research, Inc. Stable spray-dried protein formulations
AU756852B2 (en) * 1998-11-13 2003-01-23 Jagotec Ag Dry powder for inhalation
US20070212422A1 (en) * 1999-11-10 2007-09-13 Manfred Keller Dry powder for inhalation
GB9827145D0 (en) 1998-12-09 1999-02-03 Co Ordinated Drug Dev Improvements in or relating to powders
ATE294571T1 (de) * 1999-03-03 2005-05-15 Lilly Co Eli Echinocandin pharmazeutische zusammensetzungen
CN1345333A (zh) * 1999-03-03 2002-04-17 伊莱利利公司 棘白菌素/糖类复合物
IT1309592B1 (it) * 1999-03-05 2002-01-24 Chiesi Farma Spa Particelle veicolo modificate da utilizzarsi nella preparazione diformulazioni farmaceutiche sotto forma di polimeri per inalazione e
BR9917246A (pt) 1999-03-05 2002-03-26 Chiesi Farma Spa Composições farmacêuticas avançadas em pó para inalação
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
ITMI991582A1 (it) 1999-07-16 2001-01-16 Chiesi Farma Spa Polveri costituite da particelle aventi la superficie perfettamente levigata da utilizzare come veicoli per la preparazione di miscele inala
US20010036481A1 (en) * 1999-08-25 2001-11-01 Advanced Inhalation Research, Inc. Modulation of release from dry powder formulations
US6586008B1 (en) 1999-08-25 2003-07-01 Advanced Inhalation Research, Inc. Use of simple amino acids to form porous particles during spray drying
US7678364B2 (en) 1999-08-25 2010-03-16 Alkermes, Inc. Particles for inhalation having sustained release properties
US6749835B1 (en) 1999-08-25 2004-06-15 Advanced Inhalation Research, Inc. Formulation for spray-drying large porous particles
US7252840B1 (en) 1999-08-25 2007-08-07 Advanced Inhalation Research, Inc. Use of simple amino acids to form porous particles
JP4691298B2 (ja) * 1999-10-12 2011-06-01 科研製薬株式会社 粉末吸入用製剤及びその製造方法
EP1129705A1 (en) 2000-02-17 2001-09-05 Rijksuniversiteit te Groningen Powder formulation for inhalation
EP1261316B1 (en) * 2000-02-28 2008-04-23 PharmaKodex Limited Device for the delivery of oral drugs
CA2404645A1 (en) * 2000-04-11 2001-10-18 Elan Pharmaceuticals, Inc. Physically stabilized dry powder formulations
EP1276474B1 (en) * 2000-04-17 2007-06-13 Vectura Limited Formulations for use in inhaler devices
PE20011227A1 (es) 2000-04-17 2002-01-07 Chiesi Farma Spa Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros
GB0009469D0 (en) 2000-04-17 2000-06-07 Vectura Ltd Improvements in or relating to formalities for use in inhaler devices
GB0009468D0 (en) * 2000-04-17 2000-06-07 Vectura Ltd Improvements in or relating to formulations for use in inhaler devices
ATE378039T1 (de) 2000-06-27 2007-11-15 Vectura Ltd Herstellungsverfahren für partikel zur verwendung in einer arzneizusammensetzung
AU6926101A (en) * 2000-06-27 2002-01-08 Vectura Ltd Method of making particles for use in a pharmaceutical composition
CA2424021A1 (en) * 2000-09-29 2002-04-04 Board Of Trustees Operating Michigan State University Catecholamine compositions and uses thereof
EP2283818B1 (en) 2000-11-30 2017-08-02 Vectura Limited Method of making particles for use in a pharmaceutical composition
US8580306B2 (en) 2000-11-30 2013-11-12 Vectura Limited Particles for use in a pharmaceutical composition
US20040052733A1 (en) * 2000-11-30 2004-03-18 Staniforth John Nicholas Pharmaceutical compositions for inhalation
CA2429665C (en) 2000-11-30 2013-10-22 Vectura Limited Method of making particles for use in a pharmaceutical composition
GB0030074D0 (en) * 2000-12-08 2001-01-24 Univ London Pharmacy Particulate inhalation carrier
WO2002056948A1 (en) 2001-01-17 2002-07-25 Vectura Limited An inhaler device
EG24184A (en) * 2001-06-15 2008-10-08 Otsuka Pharma Co Ltd Dry powder inhalation system for transpulmonary
US6681768B2 (en) 2001-06-22 2004-01-27 Sofotec Gmbh & Co. Kg Powder formulation disintegrating system and method for dry powder inhalers
JP2005507881A (ja) * 2001-09-17 2005-03-24 グラクソ グループ リミテッド 乾燥粉末医薬製剤
AU2002346472A1 (en) * 2001-11-20 2003-06-10 Advanced Inhalation Research, Inc. Particulate compositions for improving solubility of poorly soluble agents
JP4368198B2 (ja) * 2001-11-20 2009-11-18 アルカーメス,インコーポレイテッド 肺送達用の改良された粒状組成物
EP1461020A4 (en) * 2001-12-07 2008-10-29 Map Pharmaceuticals Inc SYNTHESIS OF SMALL PARTICLES
JP2005527508A (ja) 2002-03-07 2005-09-15 ヴェクトゥラ リミテッド 経口デリバリー用急速溶融多粒子製剤
AU2006220411B2 (en) * 2002-03-20 2008-06-26 Alkermes, Inc. Inhalable Sustained Therapeutic Formulations
US7754242B2 (en) * 2002-03-20 2010-07-13 Alkermes, Inc. Inhalable sustained therapeutic formulations
AU2003230689B2 (en) * 2002-03-20 2006-06-29 Alkermes, Inc. Inhalable sustained therapeutic formulations
GB0210527D0 (en) * 2002-05-08 2002-06-19 Univ Bath Process for the treatment of particles for use in pharmaceutical formulations
US6991800B2 (en) * 2002-06-13 2006-01-31 Vicuron Pharmaceuticals Inc. Antifungal parenteral products
US20050158248A1 (en) * 2002-08-21 2005-07-21 Xian-Ming Zeng Method of preparing dry powder inhalation compositions
ATE520405T1 (de) * 2002-08-21 2011-09-15 Norton Healthcare Ltd Inhalationszusammensetzung
GB0219511D0 (en) * 2002-08-21 2002-10-02 Norton Healthcare Ltd Method of preparing dry powder inhalation compositions
AU2003279070A1 (en) * 2002-09-30 2004-04-23 Acusphere Inc Sustained release porous microparticles for inhalation
PL224720B1 (pl) * 2003-02-21 2017-01-31 Univ Bath Sposób wytwarzania cząstek krystalicznych, cząstki krystaliczne oraz kompozycja farmaceutyczna je zawierająca
EP1617820B1 (en) 2003-04-14 2018-03-21 Vectura Limited Dry power inhaler devices and dry power formulations for enhancing dosing efficiency
US20050026948A1 (en) * 2003-07-29 2005-02-03 Boehringer Ingelheim International Gmbh Medicaments for inhalation comprising an anticholinergic and a betamimetic
US20050026886A1 (en) * 2003-07-29 2005-02-03 Boehringer Ingelheim International Gmbh Medicaments for inhalation comprising an anticholinergic and a PDE IV inhibitor
EP1663164A2 (en) * 2003-09-15 2006-06-07 Vectura Limited Methods for preparing pharmaceutical compositions
GB0327723D0 (en) 2003-09-15 2003-12-31 Vectura Ltd Pharmaceutical compositions
GB0321607D0 (en) 2003-09-15 2003-10-15 Vectura Ltd Manufacture of pharmaceutical compositions
GB0326632D0 (en) 2003-11-14 2003-12-17 Jagotec Ag Dry powder formulations
MXPA06012240A (es) 2004-04-23 2007-01-31 Cydex Inc Formulacion para inhalador de polvo seco que contiene eter sulfoalquilico-ciclodextrina.
GB0409703D0 (en) 2004-04-30 2004-06-02 Vectura Ltd Pharmaceutical compositions
WO2006055950A1 (en) * 2004-11-18 2006-05-26 Nektar Therapeutics Pharmaceutical dry powder formulation on the basis particles comprising multiple active agents
GB0425758D0 (en) 2004-11-23 2004-12-22 Vectura Ltd Preparation of pharmaceutical compositions
ES2613391T3 (es) * 2005-02-10 2017-05-24 Glaxo Group Limited Procedimientos de fabricación de lactosa que utilizan técnicas de preclasificación y formulaciones farmacéuticas formadas a partir de la misma
PT2594272T (pt) 2005-05-18 2018-07-31 Horizon Orphan Llc Fluoroquinolonas aerossolizadas e suas utilizações
US8524734B2 (en) 2005-05-18 2013-09-03 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
ITMI20051999A1 (it) 2005-10-21 2007-04-22 Eratech S R L Formulazioni inalatorie di farmaci in fora di polvere secca per somministrazione come tale o con nebulizzatore e dotate di elevata erogabilita' respirabilita' e stabilita'
US7629331B2 (en) 2005-10-26 2009-12-08 Cydex Pharmaceuticals, Inc. Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof
WO2007053923A2 (en) * 2005-11-11 2007-05-18 Biolab Sanus Farmacêutica Ltda. Solid pharmaceutical composition comprising agglomerate nanoparticles and a process for producing the same
GB0525254D0 (en) 2005-12-12 2006-01-18 Jagotec Ag Powder compositions for inhalation
WO2007070851A2 (en) * 2005-12-15 2007-06-21 Acusphere, Inc. Processes for making particle-based pharmaceutical formulations for pulmonary or nasal administration
GB0602897D0 (en) * 2006-02-13 2006-03-22 Jagotec Ag Improvements In Or Relating To Dry Powder Inhaler Devices
CN101437562A (zh) * 2006-03-03 2009-05-20 Stc.Unm公司 具有气动力弹性分散机构的干粉吸入器
GB0613161D0 (en) 2006-06-30 2006-08-09 Novartis Ag Organic Compounds
GB0622818D0 (en) * 2006-11-15 2006-12-27 Jagotec Ag Improvements in or relating to organic compounds
GB0625303D0 (en) * 2006-12-19 2007-01-24 Jagotec Ag Improvements in and relating to metered dose inhalers
WO2008134817A1 (en) * 2007-05-03 2008-11-13 The University Of Sydney Composite carriers for dry powder inhalation therapy
US20090048155A1 (en) 2007-08-15 2009-02-19 Endacea, Inc. Methods for preventing and treating tissue injury and sepsis associated with Yersinia pestis infection
GB0721394D0 (en) * 2007-10-31 2007-12-12 Vectura Group Plc Compositions for trating parkinson's disease
EP2222676A4 (en) 2007-12-21 2011-10-26 Endacea Inc A1-adenosine receptor antagonistic
GB0801876D0 (en) * 2008-02-01 2008-03-12 Vectura Group Plc Suspension formulations
WO2009103035A2 (en) 2008-02-13 2009-08-20 Board Of Regents, The University Of Texas System Templated open flocs of anisotropic particles for enhanced pulmonary delivery
EP2100598A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2100599A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
US9072664B2 (en) * 2008-05-22 2015-07-07 3M Innovative Properties Company Process for manufacturing flowable powder drug compositions
WO2009158300A1 (en) * 2008-06-26 2009-12-30 3M Innovative Properties Company Dry powder pharmaceutical compositions for pulmonary administration, and methods of manufacturing thereof
WO2010002613A2 (en) * 2008-07-02 2010-01-07 3M Innovative Properties Company Method of making a dry powder pharmaceutical composition
JP5705112B2 (ja) * 2008-07-30 2015-04-22 エスティーシー.ユーエヌエム ドライパウダー吸入エアロゾル用の大径キャリア粒子を含む製剤
CN102325532B (zh) 2008-10-07 2015-06-17 Mpex医药有限公司 用于减轻肺部炎症的左氧氟沙星吸入剂
PT2344129T (pt) 2008-10-07 2018-04-23 Horizon Orphan Llc Formulações de fluoroquinolona em aerossol para farmacocinética melhorada
ES2739352T3 (es) 2009-02-26 2020-01-30 Glaxo Group Ltd Formulaciones farmacéuticas que comprenden 4-{(1R)-2-[(6-{2-[(2,6-diclorobencil)oxi]etoxi}hexil)amino]-1-hidroxietil}-2-(hidroximetil)fenol
WO2010124198A2 (en) * 2009-04-24 2010-10-28 Schering Corporation Agglomerate formulations useful in dry powder inhalers
IN2012DN02477A ( ) 2009-09-04 2015-08-21 Mpex Pharmaceuticals Inc
GB0918249D0 (en) 2009-10-19 2009-12-02 Respivert Ltd Compounds
AU2010319328A1 (en) 2009-11-12 2012-05-31 Stc.Unm Dry powder inhaler with flutter dispersion member
GB0921075D0 (en) 2009-12-01 2010-01-13 Glaxo Group Ltd Novel combination of the therapeutic agents
GB0921481D0 (en) 2009-12-08 2010-01-20 Vectura Ltd Process and product
US9877967B2 (en) 2010-01-26 2018-01-30 Endacea, Inc. Methods and pharmaceutical compositions for preventing and treating renal impairment
BR112012026804B1 (pt) 2010-04-21 2021-11-16 Chiesi Farmaceutici S.P.A. Processo para preparar partículas carreadoras de uma formulação em pó seco para inalação e processo para preparar uma formulação em pó seco para inalação
UY33337A (es) 2010-10-18 2011-10-31 Respivert Ltd DERIVADOS SUSTITUIDOS DE 1H-PIRAZOL[ 3,4-d]PIRIMIDINA COMO INHIBIDORES DE LAS FOSFOINOSITIDA 3-QUINASAS
TW201304822A (zh) 2010-11-15 2013-02-01 Vectura Ltd 組成物及用途
TW201306847A (zh) 2010-11-30 2013-02-16 Vectura Ltd 組成物及用途
EP2648788B1 (en) 2010-12-07 2017-08-09 Respira Therapeutics, Inc. Dry powder inhaler
EP4059499A1 (en) 2011-01-31 2022-09-21 Avalyn Pharma Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof
JO3510B1 (ar) * 2011-03-04 2020-07-05 Heptares Therapeutics Ltd استخدام جلايكوبيرولات لعلاج عدم انتظام دقات القلب
EP2510928A1 (en) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium for use in improving the quality of sleep in respiratory patients
LT2806855T (lt) * 2012-01-25 2018-10-10 Chiesi Farmaceutici S.P.A. Sausų miltelių kompozicija, apimanti kortikosteroidą ir beta-adrenergiką, skirta įvedimui inhaliuojant
WO2013114371A1 (en) 2012-02-01 2013-08-08 Protalix Ltd. Dry powder formulations of dnase i
US10463815B2 (en) 2012-02-21 2019-11-05 Respira Therapeutics, Inc. Inhaler to deliver substances for prophylaxis or prevention of disease or injury caused by the inhalation of biological or chemical agents
PE20142342A1 (es) 2012-03-13 2015-01-16 Respivert Ltd FORMAS CRISTALINAS DE 6-(2-((4-AMINO-3-(3-HIDROXIFENIL)-1H-PIRAZOLO[3,4-d]PIRIMIDIN-1-IL)METIL)-3-(2-CLOROBENCIL)-4-OXO-3,4-DIHIDROQUINAZOLIN-5-IL)-N,N-BIS(2-METOXIETIL)HEX-5-INAMIDA COMO INHIBIDORES DE CINASA DE FOSFOINOSITIDA 3
EP2641900A1 (en) 2012-03-20 2013-09-25 Almirall, S.A. Novel polymorphic Crystal forms of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-(R)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one, heminapadisylate as agonist of the ß2 adrenergic receptor.
GB201305825D0 (en) 2013-03-28 2013-05-15 Vectura Ltd New use
WO2014186754A2 (en) 2013-05-16 2014-11-20 Board Of Regents The University Of Texas System Dry solid aluminum adjuvant-containing vaccines and related methods thereof
CA3172586A1 (en) 2013-07-31 2015-02-05 Avalyn Pharma Inc. Aerosol imatininb compounds and uses thereof
US9427376B2 (en) * 2013-10-10 2016-08-30 Chiesi Farmaceutici S.P.A. Process for preparing pharmaceutical formulations for inhalation comprising a high-dosage strength active ingredient
JP7066321B2 (ja) 2014-01-10 2022-05-13 アヴァリン ファーマ インク. エアロゾルのピルフェニドン及びピリドンのアナログの化合物、及び、その使用
CA2943075C (en) 2014-03-19 2023-02-28 Infinity Pharmaceuticals, Inc. Heterocyclic compounds for use in the treatment of pi3k-gamma mediated disorders
WO2015179369A1 (en) 2014-05-20 2015-11-26 Infinity Pharmaceuticals, Inc. Treatment of pulmonary or respiratory diseases by inhalation administration of pi3 kinase inhibitors
TN2017000077A1 (en) 2014-09-09 2018-07-04 Vectura Ltd Formulation comprising glycopyrrolate, method and apparatus
CN107106641B (zh) 2014-10-31 2021-12-21 葛兰素史密斯克莱知识产权发展有限公司 粉末制剂
KR101990017B1 (ko) 2014-11-26 2019-06-17 벡투라 딜리버리 디바이시스 리미티드 건조 분말 흡입기
EP3838317A1 (en) 2015-01-14 2021-06-23 Respira Therapeutics, Inc. Dry powder inhaler
WO2017035408A1 (en) 2015-08-26 2017-03-02 Achillion Pharmaceuticals, Inc. Compounds for treatment of immune and inflammatory disorders
AR106018A1 (es) 2015-08-26 2017-12-06 Achillion Pharmaceuticals Inc Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos
WO2017042341A1 (en) 2015-09-09 2017-03-16 Vectura Limited Jet milling method
RU2709509C1 (ru) 2016-03-08 2019-12-18 Мерео Байофарма 1 Лимитед Режим дозирования для лечения острых обострений воспалительных состояний
MX2018010782A (es) 2016-03-08 2019-01-10 Mereo Biopharma 1 Ltd Regimen de dosificacion para el tratamiento de exacerbaciones agudas de enfermedad pulmonar obstructiva cronica.
AU2017290593A1 (en) 2016-06-27 2019-01-03 Achillion Pharmaceuticals, Inc. Quinazoline and indole compounds to treat medical disorders
HUE055425T2 (hu) 2017-12-11 2021-11-29 Mereo Biopharma 1 Ltd 3-[5-amino-4-(3-cianobenzoil)-pirazol-1-il]-N-ciklopropil-4-metilbenzamid alkalmazása krónikus elzáródásos tüdõbetegség akut fokozódásának kezelésében
US11918646B2 (en) 2017-12-11 2024-03-05 Board Of Regents, The University Of Texas System Dry adjuvanted immune stimulating compositions and use thereof for mucosal administration
KR20200097310A (ko) 2017-12-11 2020-08-18 메레오 바이오파마 1 리미티드 만성 폐쇄성 폐 질환의 급성 악화의 예방 또는 감소에서의 3-[5-아미노-4-(3-시아노벤조일)-피라졸-1-일]-n-시클로프로필-4-메틸벤즈아미드의 용도
JP2021519337A (ja) 2018-03-26 2021-08-10 シー4 セラピューティクス, インコーポレイテッド Ikarosの分解のためのセレブロン結合剤
US20230022157A1 (en) 2018-08-20 2023-01-26 Achillion Pharmaceuticals, Inc. Pharmaceutical compounds for the treatment of complement factor d medical disorders
EP3866773A4 (en) 2018-10-16 2022-10-26 Georgia State University Research Foundation, Inc. CARBON MONOXIDE PRODRUGS FOR THE TREATMENT OF MEDICAL CONDITIONS
MA55479A (fr) 2019-04-04 2022-02-09 Chiesi Farm Spa Dérivés d'isochromène utilisés en tant qu'inhibiteurs de phosphoinositide 3-kinases
AU2020356243A1 (en) 2019-09-24 2022-03-24 Chiesi Farmaceutici S.P.A. Novel carrier particles for dry powder formulations for inhalation
MX2023002285A (es) * 2020-08-26 2023-05-16 Cila Therapeutic Inc Agentes terapeuticos inhalables.
CN112451509B (zh) * 2020-12-19 2023-03-07 沈阳药科大学 一种川丁特罗吸入粉雾剂及其制备方法
WO2022240897A1 (en) 2021-05-10 2022-11-17 Sepelo Therapeutics, Llc Pharmaceutical composition comprising delafloxacin for administration into the lung
WO2023028364A1 (en) 2021-08-27 2023-03-02 Sepelo Therapeutics, Llc Targeted compositions and uses therof
WO2023196663A1 (en) * 2022-04-07 2023-10-12 Board Of Regents, The University Of Texas System Methods of preparing carrier-based dry powders for inhalation
CN115855911B (zh) * 2023-02-24 2023-06-13 湖南三友环保科技有限公司 粉末载体生物亲和性的测定方法及应用

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2533065A (en) * 1947-03-08 1950-12-05 George V Taplin Micropulverized therapeutic agents
GB786499A (en) * 1953-11-02 1957-11-20 Grace W R & Co A process of deagglomerating dried agglomerated microspheroidal gel catalyst particles
GB905723A (en) * 1959-12-10 1962-09-12 Alfred Ernest Tragham Pharmaceutical compositions comprising phenacitin
GB1132583A (en) * 1964-12-16 1968-11-06 Glaxo Lab Ltd Pharmaceutical compositions containing cephalosporins
US3957965A (en) * 1967-08-08 1976-05-18 Fisons Limited Sodium chromoglycate inhalation medicament
GB1242212A (en) * 1967-08-08 1971-08-11 Fisons Pharmaceuticals Ltd Drug for use in pharmaceutical composition
GB1242211A (en) 1967-08-08 1971-08-11 Fisons Pharmaceuticals Ltd Pharmaceutical composition
GB1230087A ( ) * 1967-08-17 1971-04-28
GB1310527A (en) * 1969-06-13 1973-03-21 Fisons Ltd Comminuting apparatus
GB1381872A (en) * 1971-06-22 1975-01-29 Fisons Ltd Pharmaceutical compositions for inhalation
GB1410588A (en) * 1971-08-10 1975-10-22 Fisons Ltd Composition
IT1197640B (it) * 1983-05-03 1988-12-06 Italsil Spa Apparecchio e metodo per la purificazione di sabbie silicee mediante attrizione
EP0187433B1 (en) * 1983-08-01 1990-12-27 Teijin Limited Powdery pharmaceutical composition suitable for application to mucosa of oral or nasal cavity
IT1204826B (it) * 1986-03-04 1989-03-10 Chiesi Farma Spa Composizioni farmaceutiche per inalazione
US5376386A (en) * 1990-01-24 1994-12-27 British Technology Group Limited Aerosol carriers
GB9001635D0 (en) * 1990-01-24 1990-03-21 Ganderton David Aerosol carriers
IL97065A (en) * 1990-02-02 1994-01-25 Fisons Plc Repellent preparations for aerosol
WO1991014422A1 (en) * 1990-03-23 1991-10-03 Minnesota Mining And Manufacturing Company The use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations
GB9024366D0 (en) * 1990-11-09 1991-01-02 Glaxo Group Ltd Medicaments
DE4140689B4 (de) * 1991-12-10 2007-11-22 Boehringer Ingelheim Kg Inhalationspulver und Verfahren zu ihrer Herstellung
AU659328B2 (en) * 1992-06-12 1995-05-11 Teijin Limited Ultrafine powder for inhalation and production thereof
KR100208979B1 (ko) * 1992-06-12 1999-07-15 야스이 쇼사꾸 기도내 투여용 제제
GB2269992A (en) * 1992-08-14 1994-03-02 Rh Ne Poulenc Rorer Limited Powder inhalation formulations
ZA94155B (en) 1992-11-06 1995-07-11 Adcock Ingram Pharma Pharmaceutical composition
SE9203743D0 (sv) * 1992-12-11 1992-12-11 Astra Ab Efficient use
TW402506B (en) * 1993-06-24 2000-08-21 Astra Ab Therapeutic preparation for inhalation
US5506203C1 (en) * 1993-06-24 2001-02-06 Astra Ab Systemic administration of a therapeutic preparation
IS1796B (is) * 1993-06-24 2001-12-31 Ab Astra Fjölpeptíð lyfjablanda til innöndunar sem einnig inniheldur eykjaefnasamband
GB9322014D0 (en) * 1993-10-26 1993-12-15 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
GB9501841D0 (en) 1995-01-31 1995-03-22 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
GB9515182D0 (en) * 1995-07-24 1995-09-20 Co Ordinated Drug Dev Improvements in and relating to powders for use in dry powder inhalers
BR9917246A (pt) * 1999-03-05 2002-03-26 Chiesi Farma Spa Composições farmacêuticas avançadas em pó para inalação
PE20011227A1 (es) * 2000-04-17 2002-01-07 Chiesi Farma Spa Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros
GB0009469D0 (en) * 2000-04-17 2000-06-07 Vectura Ltd Improvements in or relating to formalities for use in inhaler devices
ATE378039T1 (de) * 2000-06-27 2007-11-15 Vectura Ltd Herstellungsverfahren für partikel zur verwendung in einer arzneizusammensetzung
JP3486405B2 (ja) 2001-08-10 2004-01-13 三菱重工業株式会社 減揺装置

Also Published As

Publication number Publication date
EA199700153A1 (ru) 1997-12-30
PL186757B1 (pl) 2004-02-27
BR9607490B8 (pt) 2018-04-17
GB9501841D0 (en) 1995-03-22
EE9700176A (et) 1998-02-16
CZ244397A3 (cs) 1998-01-14
EP2213279A3 (en) 2010-10-13
ES2278828T3 (es) 2007-08-16
HU229965B1 (hu) 2015-03-30
SI1666023T1 (sl) 2012-01-31
DE69636961D1 (de) 2007-04-19
CN1303974C (zh) 2007-03-14
BG101858A (en) 1998-04-30
EP2258342A3 (en) 2014-01-08
EP0806938B1 (en) 2003-12-17
GB9521937D0 (en) 1996-01-03
EP1232745B1 (en) 2007-03-07
EA000352B1 (ru) 1999-04-29
US20030170183A1 (en) 2003-09-11
UA61051C2 (en) 2003-11-17
ES2213172T3 (es) 2004-08-16
DE69631119T2 (de) 2004-09-16
NO973502D0 (no) 1997-07-30
AU4545696A (en) 1996-08-21
PT806938E (pt) 2004-05-31
DK1666023T3 (da) 2012-01-30
BR9607490A (pt) 2018-04-17
CA2211874C (en) 2006-08-29
BRPI9612950B1 ( ) 2011-08-23
AU699131B2 (en) 1998-11-26
PT1666023E (pt) 2012-01-12
WO1996023485A1 (en) 1996-08-08
SI1232745T1 (sl) 2007-06-30
JP4042867B2 (ja) 2008-02-06
EP1666023A2 (en) 2006-06-07
ES2375007T3 (es) 2012-02-24
EP1666023B1 (en) 2011-10-05
CZ294259B6 (cs) 2004-11-10
FI973151A0 (fi) 1997-07-30
CN1179097A (zh) 1998-04-15
IS4531A (is) 1997-07-25
US20100330188A1 (en) 2010-12-30
KR100500694B1 (ko) 2006-03-22
US6521260B1 (en) 2003-02-18
US6153224A (en) 2000-11-28
EP1232745A1 (en) 2002-08-21
US7011818B2 (en) 2006-03-14
SK282630B6 (sk) 2002-10-08
DK1232745T3 (da) 2007-07-09
GEP19991687B (en) 1999-08-05
ATE256450T1 (de) 2004-01-15
EP2213279A2 (en) 2010-08-04
HUP9802209A2 (hu) 1999-02-01
PT1232745E (pt) 2007-04-30
FI119676B (fi) 2009-02-13
ZA96721B (en) 1996-08-19
FI973151A (fi) 1997-09-30
KR19980701844A (ko) 1998-06-25
DK0806938T3 (da) 2004-04-13
DE69636961T2 (de) 2007-06-14
EP0806938A1 (en) 1997-11-19
ATE355822T1 (de) 2007-03-15
NO324037B1 (no) 2007-07-30
ATE526946T1 (de) 2011-10-15
HK1084897A1 (en) 2006-08-11
NO973502L (no) 1997-09-30
EP1159955A1 (en) 2001-12-05
PL321572A1 (en) 1997-12-08
TR199700722T1 (xx) 1998-02-21
EP1666023A3 (en) 2009-05-06
SK103697A3 (en) 1998-01-14
US8920781B2 (en) 2014-12-30
HUP9802209A3 (en) 2000-06-28
EP2258342A2 (en) 2010-12-08
BRPI9612950B8 (pt) 2018-04-17
US7718163B2 (en) 2010-05-18
BR9612950B1 (pt) 2011-08-23
MX9705847A (es) 1998-08-30
CA2211874A1 (en) 1996-08-08
US20060029552A1 (en) 2006-02-09
DE69631119D1 (de) 2004-01-29
JPH10513174A (ja) 1998-12-15

Similar Documents

Publication Publication Date Title
NZ300654A (en) Carrier particles and active particles with additive material for use in dry inhalers
PL347640A1 (en) Dry powder for inhalation
GB2179257B (en) Absorbent articles
MXPA02010213A (es) Mejoras en, o relacionadas con formulaciones para usarse en aparatos inhiladores.
MY132999A (en) New formulation for inhalation
HK1025516A1 (en) New formulation for inhalation having a poured bulk density of from 0.28 to 0.38 g/ml, comprising budesonide
JPS54129128A (en) Powered pesticide having suppressed static electrification

Legal Events

Date Code Title Description
RENW Renewal (renewal fees accepted)
RENW Renewal (renewal fees accepted)
RENW Renewal (renewal fees accepted)
ASS Change of ownership

Owner name: VECTURA LIMITED, GB

Free format text: OLD OWNER(S): VECTURA LIMITED

EXPY Patent expired