NZ264887A - Heterocyclic carboxamides - Google Patents
Heterocyclic carboxamidesInfo
- Publication number
- NZ264887A NZ264887A NZ264887A NZ26488794A NZ264887A NZ 264887 A NZ264887 A NZ 264887A NZ 264887 A NZ264887 A NZ 264887A NZ 26488794 A NZ26488794 A NZ 26488794A NZ 264887 A NZ264887 A NZ 264887A
- Authority
- NZ
- New Zealand
- Prior art keywords
- group
- ring
- compound
- stands
- optionally substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NZ272711A NZ272711A (en) | 1993-11-10 | 1995-08-03 | Use of n-benzyl (or phenethyl) fused azaheterocyclic carboxamide derivatives to antagonise tachykinin receptors in mammals |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP28117893 | 1993-11-10 | ||
| JP33748893 | 1993-12-28 | ||
| JP3363794 | 1994-03-03 | ||
| JP13855194 | 1994-06-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ264887A true NZ264887A (en) | 1996-12-20 |
Family
ID=27459814
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ264887A NZ264887A (en) | 1993-11-10 | 1994-11-09 | Heterocyclic carboxamides |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5585385A (https=) |
| EP (1) | EP0652218B1 (https=) |
| KR (1) | KR950014108A (https=) |
| CN (1) | CN1052004C (https=) |
| AT (1) | ATE203024T1 (https=) |
| AU (1) | AU678295B2 (https=) |
| BR (1) | BR9404403A (https=) |
| CA (1) | CA2135440A1 (https=) |
| DE (1) | DE69427675T2 (https=) |
| FI (1) | FI945281A7 (https=) |
| HU (1) | HUT68810A (https=) |
| IL (1) | IL111590A0 (https=) |
| NO (1) | NO301764B1 (https=) |
| NZ (1) | NZ264887A (https=) |
| RU (1) | RU2135471C1 (https=) |
| TW (1) | TW263498B (https=) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5770590A (en) * | 1995-03-24 | 1998-06-23 | Takeda Chemical Industries, Ltd. | Cyclic compounds, their prudiction and use |
| ATE242243T1 (de) * | 1995-03-24 | 2003-06-15 | Takeda Chemical Industries Ltd | Zyklische verbindungen, ihre herstellung und ihre verwendung als tachykininrezeptorantagonisten |
| FR2732221B1 (fr) * | 1995-03-28 | 1997-04-25 | Oreal | Utilisation d'un antagoniste de cgrp pour traiter les rougeurs cutanees d'origine neurogene et composition obtenue |
| GB9524104D0 (en) * | 1995-11-24 | 1996-01-24 | Smithkline Beecham Spa | Novel compounds |
| US6087373A (en) * | 1997-09-23 | 2000-07-11 | Merck & Co., Inc. | Thrombin inhibitors |
| WO1999015169A1 (en) * | 1997-09-23 | 1999-04-01 | Merck & Co., Inc. | Thrombin inhibitors |
| US5939432A (en) * | 1997-10-29 | 1999-08-17 | Medco Research, Inc. | Thiophenes useful for modulating the adenosine receptor |
| US6323214B1 (en) | 1997-10-29 | 2001-11-27 | Medco Research, Inc | Allosteric adenosine receptor modulators |
| US6727258B2 (en) * | 1997-10-29 | 2004-04-27 | King Pharmaceutical Research & Development, Inc. | Allosteric adenosine receptor modulators |
| AU5305299A (en) * | 1998-08-26 | 2000-03-21 | Tanabe Seiyaku Co., Ltd. | Naphthyridine derivatives and process for the preparation thereof |
| WO2000023443A1 (en) * | 1998-10-22 | 2000-04-27 | Akzo Nobel N.V. | Tetrahydropyridopyridine derivatives and intermediates for producing the same |
| US6239132B1 (en) | 1999-04-23 | 2001-05-29 | Merck & Co., Inc. | Thrombin inhibitors |
| EP1189618A4 (en) | 1999-06-04 | 2002-06-19 | Merck & Co Inc | thrombin |
| US20040152727A1 (en) * | 2001-05-18 | 2004-08-05 | Hay Douglas William Pierre | Novel use |
| EP1457493A4 (en) * | 2001-12-10 | 2005-11-30 | Kyorin Seiyaku Kk | CONDENSED, BICYCLIC PYRIDINE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS |
| ATE427310T1 (de) | 2002-01-18 | 2009-04-15 | Kyorin Seiyaku Kk | Kondensierte bicyclische pyrimidinderivate |
| AU2003211931A1 (en) * | 2002-02-13 | 2003-09-04 | Takeda Chemical Industries, Ltd. | Jnk inhibitor |
| WO2003077857A2 (en) * | 2002-03-15 | 2003-09-25 | Merck & Co., Inc. | N-(substituted benzyl)-8-hydroxy-1,6-naphthyridine-7- carboxamides useful as hiv integrase inhibitors |
| KR20040099367A (ko) | 2002-03-26 | 2004-11-26 | 교린 세이야꾸 가부시키 가이샤 | 타키키닌 수용체 길항제로서의 축합 바이사이클릭 피리딘 유도체 |
| CA2509233A1 (en) * | 2002-12-13 | 2004-07-01 | Neurogen Corporation | 2-substituted quinazolin-4-ylamine analogues as capsaicin receptor modulators |
| RU2229475C1 (ru) * | 2003-03-06 | 2004-05-27 | ООО "Исследовательский институт химического разнообразия | 6-сульфамоилхинолин-4-карбоновые кислоты, их производные и комбинаторная библиотека |
| CA2539760C (en) * | 2003-09-23 | 2011-01-25 | Merck & Co., Inc. | Quinoline potassium channel inhibitors |
| CN1856473A (zh) * | 2003-09-23 | 2006-11-01 | 默克公司 | 异喹啉酮钾通道抑制剂 |
| WO2005068427A1 (ja) * | 2004-01-14 | 2005-07-28 | Takeda Pharmaceutical Company Limited | カルボキサミド誘導体およびその用途 |
| KR100781704B1 (ko) * | 2005-04-20 | 2007-12-03 | 에스케이케미칼주식회사 | 피리딘 유도체와 이의 제조방법, 및 이를 포함하는약제조성물 |
| AR057325A1 (es) | 2005-05-25 | 2007-11-28 | Progenics Pharm Inc | Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos |
| TW200740782A (en) * | 2005-09-01 | 2007-11-01 | Tanabe Seiyaku Co | Thiomorpholine compound and process for preparing the same |
| RU2359962C1 (ru) * | 2007-12-13 | 2009-06-27 | Общество с ограниченной ответственностью "Консорциум-ПИК" (ООО "Консорциум-ПИК") | Нейротропное средство и способ его получения |
| RU2429230C1 (ru) * | 2010-05-27 | 2011-09-20 | Учреждение Российской академии наук Институт проблем химико-энергетических технологий Сибирского отделения РАН (ИПХЭТ СО РАН) | Способ получения n-метил-4-бензилкарбамидопиридиния йодида |
| EP2681200A4 (en) * | 2011-03-03 | 2015-05-27 | Zalicus Pharmaceuticals Ltd | INHIBITORS OF BENZIMIDAZOLE TYPE OF SODIUM CHANNEL |
| CN102358730A (zh) * | 2011-08-24 | 2012-02-22 | 济南赛文医药技术有限公司 | 一种小分子mek蛋白激酶抑制剂 |
| WO2013097052A1 (en) * | 2011-12-30 | 2013-07-04 | Abbott Laboratories | Bromodomain inhibitors |
| EP2920183B1 (en) | 2012-11-14 | 2017-03-08 | Glaxosmithkline LLC | Thieno[3,2-c]pyridin-4(5h)-ones as bet inhibitors |
| JP2016525503A (ja) * | 2013-06-28 | 2016-08-25 | アッヴィ・インコーポレイテッド | ブロモドメイン阻害剤 |
| CA2978736C (en) | 2015-03-04 | 2023-11-07 | Vanda Pharmaceuticals Inc. | Dosing regimen of tradipitant |
| EP3133065A1 (en) | 2015-08-21 | 2017-02-22 | Merck Patent GmbH | Compounds for optically active devices |
| CA3018802A1 (en) | 2016-04-15 | 2017-10-19 | Abbvie Inc. | Bromodomain inhibitors |
| EP3363786A1 (en) | 2017-02-15 | 2018-08-22 | Merck Patent GmbH | Compounds for optically active devices |
| EP3363793A1 (en) | 2017-02-15 | 2018-08-22 | Merck Patent GmbH | Hydrophobic compounds for optically active devices |
| CA3073998A1 (en) | 2017-09-13 | 2019-03-21 | Vanda Pharmaceuticals Inc. | Improved treatment of atopic dermatitis with tradipitant |
| WO2021195205A1 (en) | 2020-03-26 | 2021-09-30 | Vanda Pharmaceuticals Inc. | Treatment of lower respiratory tract infection with tradipitant |
| JP7763397B2 (ja) | 2020-05-20 | 2025-11-04 | エイエムオー・アイルランド | 光学活性装置で使用するためのアザクマリン及びアザチオクマリン誘導体 |
| WO2021257857A1 (en) | 2020-06-19 | 2021-12-23 | Incyte Corporation | Naphthyridinone compounds as jak2 v617f inhibitors |
| WO2021257863A1 (en) | 2020-06-19 | 2021-12-23 | Incyte Corporation | Pyrrolotriazine compounds as jak2 v617f inhibitors |
| US11767323B2 (en) | 2020-07-02 | 2023-09-26 | Incyte Corporation | Tricyclic pyridone compounds as JAK2 V617F inhibitors |
| SMT202500271T1 (it) | 2020-07-02 | 2025-09-12 | Incyte Corp | Composti di urea triciclici come inibitori di v617f di jak2 |
| US11661422B2 (en) | 2020-08-27 | 2023-05-30 | Incyte Corporation | Tricyclic urea compounds as JAK2 V617F inhibitors |
| WO2022140231A1 (en) | 2020-12-21 | 2022-06-30 | Incyte Corporation | Deazaguaine compounds as jak2 v617f inhibitors |
| AR125273A1 (es) | 2021-02-25 | 2023-07-05 | Incyte Corp | Lactamas espirocíclicas como inhibidores de jak2 v617f |
| CN119173514A (zh) | 2022-03-17 | 2024-12-20 | 因赛特公司 | 作为jak2 v617f抑制剂的三环脲化合物 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU173438B (hu) * | 1975-11-27 | 1979-05-28 | Chinoin Gyogyszer Es Vegyeszet | Sposob poluchenija novykh proizvodnykh 4-okso-1,6,7,8-/tetragidro-4h-pirido/1,2/pirimidina s zaderzhivajuhhejj vozgoranie aktivnot'ju i protivosvertivajuhhem effektom |
| IL75987A (en) * | 1984-08-25 | 1991-07-18 | Goedecke Ag | Tri-and tetrasubstituted-1,4-dihydro-1,6-naphthyridine-3-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them |
| IE892088L (en) * | 1988-07-12 | 1990-01-12 | William Henry Deryk Morris | Quinoline derivatives, their production and use |
| TW205037B (https=) * | 1989-10-06 | 1993-05-01 | Takeda Pharm Industry Co Ltd | |
| FR2654725B1 (fr) * | 1989-11-23 | 1992-02-14 | Rhone Poulenc Sante | Nouveaux derives de l'isoindolone, leur preparation et les compositions pharmaceutiques qui les contiennent. |
| UA41251C2 (uk) * | 1990-01-04 | 2001-09-17 | Пфайзер, Інк. | Гідровані азотвмісні гетероциклічні сполуки, похідні піперидину, фармацевтична композиція та спосіб пригнічення активності речовини р в організмі |
| US5278186A (en) * | 1990-02-10 | 1994-01-11 | Takeda Chemical Industries, Ltd. | Chromene derivatives, their production and use |
| US5143919A (en) * | 1990-08-17 | 1992-09-01 | Takeda Chemical Industries, Ltd. | Thienopyridine derivatives and their pharmaceutical use |
| DE69110828T2 (de) * | 1990-10-16 | 1995-11-30 | Takeda Chemical Industries Ltd | Heterozyklische Aminderivate, deren Herstellung und deren Verwendung. |
| TW241258B (https=) * | 1992-04-15 | 1995-02-21 | Takeda Pharm Industry Co Ltd | |
| DE4215588A1 (de) * | 1992-05-12 | 1993-11-18 | Bayer Ag | Biphenylmethyl-substituierte Pyridone |
| DE4215587A1 (de) * | 1992-05-12 | 1993-11-18 | Bayer Ag | Sulfonylbenzyl-substituierte Benzo- und Pyridopyridone |
| EP0585913B1 (en) * | 1992-09-04 | 1997-12-29 | Takeda Chemical Industries, Ltd. | Condensed heterocyclic compounds, their production and use |
| JPH06298757A (ja) * | 1993-04-15 | 1994-10-25 | Kissei Pharmaceut Co Ltd | ピペリジノ−３，４−ジヒドロカルボスチリル誘導体 |
-
1994
- 1994-11-05 TW TW083110229A patent/TW263498B/zh active
- 1994-11-08 EP EP94117576A patent/EP0652218B1/en not_active Expired - Lifetime
- 1994-11-08 NO NO944252A patent/NO301764B1/no not_active IP Right Cessation
- 1994-11-08 DE DE69427675T patent/DE69427675T2/de not_active Expired - Fee Related
- 1994-11-08 AT AT94117576T patent/ATE203024T1/de not_active IP Right Cessation
- 1994-11-09 AU AU77738/94A patent/AU678295B2/en not_active Ceased
- 1994-11-09 NZ NZ264887A patent/NZ264887A/en unknown
- 1994-11-09 CA CA002135440A patent/CA2135440A1/en not_active Abandoned
- 1994-11-09 RU RU94040174A patent/RU2135471C1/ru active
- 1994-11-09 BR BR9404403A patent/BR9404403A/pt not_active Application Discontinuation
- 1994-11-09 FI FI945281A patent/FI945281A7/fi unknown
- 1994-11-10 KR KR1019940029451A patent/KR950014108A/ko not_active Abandoned
- 1994-11-10 US US08/338,762 patent/US5585385A/en not_active Expired - Fee Related
- 1994-11-10 CN CN94113866A patent/CN1052004C/zh not_active Expired - Fee Related
- 1994-11-10 IL IL11159094A patent/IL111590A0/xx unknown
- 1994-11-10 HU HU9403230A patent/HUT68810A/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1107476A (zh) | 1995-08-30 |
| CN1052004C (zh) | 2000-05-03 |
| US5585385A (en) | 1996-12-17 |
| HUT68810A (en) | 1995-05-19 |
| NO944252D0 (no) | 1994-11-08 |
| BR9404403A (pt) | 1995-07-18 |
| DE69427675D1 (de) | 2001-08-16 |
| TW263498B (https=) | 1995-11-21 |
| FI945281L (fi) | 1995-05-11 |
| EP0652218B1 (en) | 2001-07-11 |
| IL111590A0 (en) | 1995-01-24 |
| NO944252L (no) | 1995-05-11 |
| FI945281A7 (fi) | 1995-05-11 |
| RU2135471C1 (ru) | 1999-08-27 |
| DE69427675T2 (de) | 2002-05-16 |
| RU94040174A (ru) | 1996-10-10 |
| AU678295B2 (en) | 1997-05-22 |
| FI945281A0 (fi) | 1994-11-09 |
| AU7773894A (en) | 1995-05-18 |
| ATE203024T1 (de) | 2001-07-15 |
| HU9403230D0 (en) | 1995-01-30 |
| NO301764B1 (no) | 1997-12-08 |
| EP0652218A1 (en) | 1995-05-10 |
| CA2135440A1 (en) | 1995-05-11 |
| KR950014108A (ko) | 1995-06-15 |
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