NZ242941A - Substituted diaminophthalimide derivatives and pharmaceutical compositions - Google Patents

Substituted diaminophthalimide derivatives and pharmaceutical compositions

Info

Publication number
NZ242941A
NZ242941A NZ242941A NZ24294192A NZ242941A NZ 242941 A NZ242941 A NZ 242941A NZ 242941 A NZ242941 A NZ 242941A NZ 24294192 A NZ24294192 A NZ 24294192A NZ 242941 A NZ242941 A NZ 242941A
Authority
NZ
New Zealand
Prior art keywords
phenyl
lower alkyl
hydrogen
formula
hydroxy
Prior art date
Application number
NZ242941A
Other languages
English (en)
Inventor
Uwe Trinks
Peter Traxler
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of NZ242941A publication Critical patent/NZ242941A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/46Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Luminescent Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Stringed Musical Instruments (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Electrophonic Musical Instruments (AREA)
  • Pyridine Compounds (AREA)
NZ242941A 1991-05-30 1992-05-28 Substituted diaminophthalimide derivatives and pharmaceutical compositions NZ242941A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH160191 1991-05-30

Publications (1)

Publication Number Publication Date
NZ242941A true NZ242941A (en) 1994-10-26

Family

ID=4214234

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ242941A NZ242941A (en) 1991-05-30 1992-05-28 Substituted diaminophthalimide derivatives and pharmaceutical compositions

Country Status (25)

Country Link
EP (1) EP0516588B1 (enrdf_load_stackoverflow)
JP (1) JP2593273B2 (enrdf_load_stackoverflow)
KR (1) KR920021508A (enrdf_load_stackoverflow)
CN (1) CN1067052A (enrdf_load_stackoverflow)
AT (1) ATE108437T1 (enrdf_load_stackoverflow)
AU (1) AU653024B2 (enrdf_load_stackoverflow)
CA (1) CA2069857A1 (enrdf_load_stackoverflow)
CS (1) CS156792A3 (enrdf_load_stackoverflow)
CY (1) CY1979A (enrdf_load_stackoverflow)
DE (1) DE59200277D1 (enrdf_load_stackoverflow)
DK (1) DK0516588T3 (enrdf_load_stackoverflow)
ES (1) ES2056699T3 (enrdf_load_stackoverflow)
FI (1) FI100530B (enrdf_load_stackoverflow)
HK (1) HK214896A (enrdf_load_stackoverflow)
HU (1) HUT66655A (enrdf_load_stackoverflow)
IE (1) IE65772B1 (enrdf_load_stackoverflow)
IL (1) IL102038A0 (enrdf_load_stackoverflow)
MA (1) MA22540A1 (enrdf_load_stackoverflow)
MX (1) MX9202544A (enrdf_load_stackoverflow)
NO (1) NO178261C (enrdf_load_stackoverflow)
NZ (1) NZ242941A (enrdf_load_stackoverflow)
PL (1) PL170909B1 (enrdf_load_stackoverflow)
RU (1) RU2095349C1 (enrdf_load_stackoverflow)
TW (1) TW204341B (enrdf_load_stackoverflow)
ZA (1) ZA923940B (enrdf_load_stackoverflow)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5491144A (en) * 1991-05-30 1996-02-13 Ciba-Geigy Corporation Substituted diaminophthalimides and analogues
EP0600830A1 (de) * 1992-11-27 1994-06-08 Ciba-Geigy Ag Substituierte Derivate von Diaminophthalimid als Protein-Tyrosin-Kinase-Hemmer
EP0600831A1 (de) * 1992-11-27 1994-06-08 Ciba-Geigy Ag Phthalazinonderivate
ATE185698T1 (de) * 1993-06-25 1999-11-15 Main Camp Marketing Pty Ltd Therapeutisches agens
AU691815B2 (en) * 1993-06-25 1998-05-28 Main Camp Marketing Pty. Ltd. Therapeutic agent
GB9314893D0 (en) * 1993-07-19 1993-09-01 Zeneca Ltd Quinazoline derivatives
GB9325217D0 (en) * 1993-12-09 1994-02-09 Zeneca Ltd Pyrimidine derivatives
WO1995024190A2 (en) * 1994-03-07 1995-09-14 Sugen, Inc. Receptor tyrosine kinase inhibitors for inhibiting cell proliferative disorders and compositions thereof
GB9600545D0 (en) 1996-01-11 1996-03-13 Ciba Geigy Ag Compositions
EP1661566A3 (en) * 1996-08-05 2008-04-16 Myriad Genetics, Inc. Use of beta-sheet mimetics as protease and kinase inhibitors and as inhibitors of transcription factors
AU732174B2 (en) * 1996-08-05 2001-04-12 Myriad Genetics, Inc. Use of beta-sheet mimetics as protease and kinase inhibitors and as inhibitors of transcription factors
AU2002354114A1 (en) * 2001-11-30 2003-06-10 Matsushita Electric Industrial Co., Ltd. Bisimide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition
US20050182061A1 (en) * 2003-10-02 2005-08-18 Jeremy Green Phthalimide compounds useful as protein kinase inhibitors
WO2006047514A2 (en) * 2004-10-25 2006-05-04 Whitehead Institute For Biomedical Research Daph analogs and inhibition of protein aggregation
WO2006112479A1 (ja) * 2005-04-19 2006-10-26 Kyowa Hakko Kogyo Co., Ltd. 含窒素複素環化合物
DE102009031058A1 (de) * 2009-06-30 2011-01-27 Clariant International Ltd. Kontinuierliches Verfahren zur Herstellung von Amiden aromatischer Carbonsäuren
JP5934559B2 (ja) * 2012-04-05 2016-06-15 国立大学法人京都工芸繊維大学 発光材料および有機el素子
CN105434432B (zh) * 2015-12-04 2018-11-13 中国科学院昆明植物研究所 N-羟基邻苯二甲酰亚胺类化合物在制备抗肿瘤药物中的应用
EP4367112A1 (en) 2021-07-09 2024-05-15 Plexium, Inc. Aryl compounds and pharmaceutical compositions that modulate ikzf2

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3857947A (en) * 1972-08-14 1974-12-31 Stauffer Chemical Co Fungicidal active phthalimides
GB1581073A (en) * 1976-09-08 1980-12-10 Campbell Chain Co Locking assembly
JPS60161968A (ja) * 1984-01-31 1985-08-23 Sankyo Co Ltd フタ−ルイミド誘導体及び農業用殺菌剤

Also Published As

Publication number Publication date
PL294701A1 (enrdf_load_stackoverflow) 1993-02-08
CN1067052A (zh) 1992-12-16
HK214896A (en) 1996-12-13
ES2056699T3 (es) 1994-10-01
FI100530B (fi) 1997-12-31
DK0516588T3 (da) 1994-08-15
PL170909B1 (pl) 1997-02-28
KR920021508A (ko) 1992-12-18
AU1705392A (en) 1992-12-03
NO922133L (no) 1992-12-01
CA2069857A1 (en) 1992-12-01
AU653024B2 (en) 1994-09-15
DE59200277D1 (de) 1994-08-18
RU2095349C1 (ru) 1997-11-10
IL102038A0 (en) 1992-12-30
NO922133D0 (no) 1992-05-29
MA22540A1 (fr) 1992-12-31
CY1979A (en) 1997-09-05
NO178261B (no) 1995-11-13
IE921770A1 (en) 1992-12-02
EP0516588A1 (de) 1992-12-02
FI922459L (fi) 1992-12-01
CS156792A3 (en) 1992-12-16
NO178261C (no) 1996-02-21
MX9202544A (es) 1992-11-01
EP0516588B1 (de) 1994-07-13
JP2593273B2 (ja) 1997-03-26
HUT66655A (en) 1994-12-28
FI922459A0 (fi) 1992-05-27
HU9201789D0 (en) 1992-08-28
TW204341B (enrdf_load_stackoverflow) 1993-04-21
JPH05163240A (ja) 1993-06-29
ZA923940B (en) 1993-11-15
IE65772B1 (en) 1995-11-15
ATE108437T1 (de) 1994-07-15

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