CY1979A - Substituted diaminophtalimides and analogues - Google Patents
Substituted diaminophtalimides and analoguesInfo
- Publication number
- CY1979A CY1979A CY197997A CY197997A CY1979A CY 1979 A CY1979 A CY 1979A CY 197997 A CY197997 A CY 197997A CY 197997 A CY197997 A CY 197997A CY 1979 A CY1979 A CY 1979A
- Authority
- CY
- Cyprus
- Prior art keywords
- diaminophtalimides
- analogues
- substituted
- inhibition
- compounds
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 102000001253 Protein Kinase Human genes 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 108060006633 protein kinase Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Luminescent Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Enzymes And Modification Thereof (AREA)
- Electrophonic Musical Instruments (AREA)
- Stringed Musical Instruments (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Pyridine Compounds (AREA)
Abstract
Compounds of the formula I <IMAGE> in which Ar1, Ar2, A1, A2, R and X have the meanings given in the description, have useful pharmaceutical properties and are particularly active against diseases responsive to the inhibition of protein kinases, for example tumours. They are prepared in a manner known per se.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH160191 | 1991-05-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1979A true CY1979A (en) | 1997-09-05 |
Family
ID=4214234
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY197997A CY1979A (en) | 1991-05-30 | 1997-09-05 | Substituted diaminophtalimides and analogues |
Country Status (25)
| Country | Link |
|---|---|
| EP (1) | EP0516588B1 (en) |
| JP (1) | JP2593273B2 (en) |
| KR (1) | KR920021508A (en) |
| CN (1) | CN1067052A (en) |
| AT (1) | ATE108437T1 (en) |
| AU (1) | AU653024B2 (en) |
| CA (1) | CA2069857A1 (en) |
| CS (1) | CS156792A3 (en) |
| CY (1) | CY1979A (en) |
| DE (1) | DE59200277D1 (en) |
| DK (1) | DK0516588T3 (en) |
| ES (1) | ES2056699T3 (en) |
| FI (1) | FI100530B (en) |
| HK (1) | HK214896A (en) |
| HU (1) | HUT66655A (en) |
| IE (1) | IE65772B1 (en) |
| IL (1) | IL102038A0 (en) |
| MA (1) | MA22540A1 (en) |
| MX (1) | MX9202544A (en) |
| NO (1) | NO178261C (en) |
| NZ (1) | NZ242941A (en) |
| PL (1) | PL170909B1 (en) |
| RU (1) | RU2095349C1 (en) |
| TW (1) | TW204341B (en) |
| ZA (1) | ZA923940B (en) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5491144A (en) * | 1991-05-30 | 1996-02-13 | Ciba-Geigy Corporation | Substituted diaminophthalimides and analogues |
| EP0600830A1 (en) * | 1992-11-27 | 1994-06-08 | Ciba-Geigy Ag | Substituted derivatives of diaminophthalimide as protein-tyrosine kinase inhibitors |
| EP0600831A1 (en) * | 1992-11-27 | 1994-06-08 | Ciba-Geigy Ag | Phtalazinon derivatives |
| DE69421280T2 (en) * | 1993-06-25 | 2000-07-13 | Main Camp Marketing Pty. Ltd., Ballina | THERAPEUTIC AGENT |
| AU691815B2 (en) * | 1993-06-25 | 1998-05-28 | Main Camp Marketing Pty. Ltd. | Therapeutic agent |
| GB9314893D0 (en) * | 1993-07-19 | 1993-09-01 | Zeneca Ltd | Quinazoline derivatives |
| GB9325217D0 (en) * | 1993-12-09 | 1994-02-09 | Zeneca Ltd | Pyrimidine derivatives |
| AU2096895A (en) | 1994-03-07 | 1995-09-25 | Sugen, Incorporated | Receptor tyrosine kinase inhibitors for inhibiting cell proliferative disorders and compositions thereof |
| GB9600545D0 (en) | 1996-01-11 | 1996-03-13 | Ciba Geigy Ag | Compositions |
| EP1661566A3 (en) * | 1996-08-05 | 2008-04-16 | Myriad Genetics, Inc. | Use of beta-sheet mimetics as protease and kinase inhibitors and as inhibitors of transcription factors |
| DE69735545T2 (en) * | 1996-08-05 | 2006-08-10 | Myriad Genetics, Inc., Salt Lake City | USE OF BETA LEAF MIMETIKA AS A PROTEASE AND KINASE INHIBITOR AND ALSHEMMER OF A TRANSCRIPTION FACTOR |
| US7374857B2 (en) * | 2001-11-30 | 2008-05-20 | Wako Pure Chemical Industries Ltd. | Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition |
| US20050182061A1 (en) * | 2003-10-02 | 2005-08-18 | Jeremy Green | Phthalimide compounds useful as protein kinase inhibitors |
| WO2006047514A2 (en) * | 2004-10-25 | 2006-05-04 | Whitehead Institute For Biomedical Research | Daph analogs and inhibition of protein aggregation |
| JP4257926B2 (en) * | 2005-04-19 | 2009-04-30 | 協和発酵キリン株式会社 | Nitrogen-containing heterocyclic compounds |
| DE102009031058A1 (en) * | 2009-06-30 | 2011-01-27 | Clariant International Ltd. | Continuous process for the preparation of amides of aromatic carboxylic acids |
| JP5934559B2 (en) * | 2012-04-05 | 2016-06-15 | 国立大学法人京都工芸繊維大学 | Luminescent material and organic EL device |
| CN105434432B (en) * | 2015-12-04 | 2018-11-13 | 中国科学院昆明植物研究所 | N-Hydroxyphthalimide class compound application in preparation of anti-tumor drugs |
| TW202317546A (en) | 2021-07-09 | 2023-05-01 | 美商普萊克斯姆公司 | Aryl compounds and pharmaceutical compositions that modulate ikzf2 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3857947A (en) * | 1972-08-14 | 1974-12-31 | Stauffer Chemical Co | Fungicidal active phthalimides |
| GB1581073A (en) * | 1976-09-08 | 1980-12-10 | Campbell Chain Co | Locking assembly |
| JPS60161968A (en) * | 1984-01-31 | 1985-08-23 | Sankyo Co Ltd | Phthalimide derivative and agricultural germicide |
-
1992
- 1992-05-20 AU AU17053/92A patent/AU653024B2/en not_active Ceased
- 1992-05-21 AT AT92810385T patent/ATE108437T1/en not_active IP Right Cessation
- 1992-05-21 DK DK92810385.2T patent/DK0516588T3/en active
- 1992-05-21 DE DE59200277T patent/DE59200277D1/en not_active Expired - Fee Related
- 1992-05-21 EP EP92810385A patent/EP0516588B1/en not_active Expired - Lifetime
- 1992-05-21 ES ES92810385T patent/ES2056699T3/en not_active Expired - Lifetime
- 1992-05-25 CS CS921567A patent/CS156792A3/en unknown
- 1992-05-26 TW TW081104093A patent/TW204341B/zh active
- 1992-05-27 PL PL92294701A patent/PL170909B1/en unknown
- 1992-05-27 FI FI922459A patent/FI100530B/en not_active IP Right Cessation
- 1992-05-28 CA CA002069857A patent/CA2069857A1/en not_active Abandoned
- 1992-05-28 HU HU9201789A patent/HUT66655A/en unknown
- 1992-05-28 MX MX9202544A patent/MX9202544A/en not_active IP Right Cessation
- 1992-05-28 IL IL102038A patent/IL102038A0/en unknown
- 1992-05-28 NZ NZ242941A patent/NZ242941A/en unknown
- 1992-05-29 NO NO922133A patent/NO178261C/en unknown
- 1992-05-29 KR KR1019920009286A patent/KR920021508A/en not_active Abandoned
- 1992-05-29 JP JP4138985A patent/JP2593273B2/en not_active Expired - Lifetime
- 1992-05-29 MA MA22828A patent/MA22540A1/en unknown
- 1992-05-29 ZA ZA923940A patent/ZA923940B/en unknown
- 1992-05-29 CN CN92104118A patent/CN1067052A/en active Pending
- 1992-05-29 RU SU925011857A patent/RU2095349C1/en active
- 1992-07-01 IE IE921770A patent/IE65772B1/en not_active IP Right Cessation
-
1996
- 1996-12-12 HK HK214896A patent/HK214896A/en not_active IP Right Cessation
-
1997
- 1997-09-05 CY CY197997A patent/CY1979A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI100530B (en) | 1997-12-31 |
| EP0516588A1 (en) | 1992-12-02 |
| EP0516588B1 (en) | 1994-07-13 |
| NO178261C (en) | 1996-02-21 |
| MA22540A1 (en) | 1992-12-31 |
| ATE108437T1 (en) | 1994-07-15 |
| RU2095349C1 (en) | 1997-11-10 |
| DE59200277D1 (en) | 1994-08-18 |
| AU653024B2 (en) | 1994-09-15 |
| PL294701A1 (en) | 1993-02-08 |
| IE65772B1 (en) | 1995-11-15 |
| TW204341B (en) | 1993-04-21 |
| CN1067052A (en) | 1992-12-16 |
| DK0516588T3 (en) | 1994-08-15 |
| NO178261B (en) | 1995-11-13 |
| NZ242941A (en) | 1994-10-26 |
| KR920021508A (en) | 1992-12-18 |
| JPH05163240A (en) | 1993-06-29 |
| IE921770A1 (en) | 1992-12-02 |
| ES2056699T3 (en) | 1994-10-01 |
| CS156792A3 (en) | 1992-12-16 |
| MX9202544A (en) | 1992-11-01 |
| JP2593273B2 (en) | 1997-03-26 |
| HUT66655A (en) | 1994-12-28 |
| CA2069857A1 (en) | 1992-12-01 |
| FI922459A0 (en) | 1992-05-27 |
| AU1705392A (en) | 1992-12-03 |
| HU9201789D0 (en) | 1992-08-28 |
| PL170909B1 (en) | 1997-02-28 |
| ZA923940B (en) | 1993-11-15 |
| IL102038A0 (en) | 1992-12-30 |
| NO922133L (en) | 1992-12-01 |
| HK214896A (en) | 1996-12-13 |
| FI922459L (en) | 1992-12-01 |
| NO922133D0 (en) | 1992-05-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY1979A (en) | Substituted diaminophtalimides and analogues | |
| NZ244021A (en) | Benzylthiazolidinedione derivatives, preparation and pharmaceutical compositions thereof | |
| GR3018182T3 (en) | Derivatives of amidinophenylalanine, procedure for their preparation, their utilisation and anticoagulant compositions comprising them. | |
| HUT68963A (en) | Novel 4-arylpiperazines and 4-arylpiperidines, pharmaceutical compositions comprising them and the proces for producing thereof | |
| DE59203976D1 (en) | Hydantoin derivatives. | |
| IL81002A (en) | 3,4-diphenyl-pyrazoline-1-carboxamide derivatives,processes for the preparation thereof and insecticidal and acaricidal compositions containing the same | |
| HUT61004A (en) | Process for producing quinoxaline derivatives and pharmaceutical compositions comprising such compounds as active ingredient | |
| EP0387821A3 (en) | 2-alkyl-4-arylmethylaminoquinolines, their use and medicines containing them | |
| KR960703863A (en) | New Bis-naphthalimides for the Treatment of Cancer | |
| ES2104682T3 (en) | FLUORINE-COMPOUNDS. | |
| EP0331092A3 (en) | Alpha-amino-carboxylic-acid derivatives, their preparation and use | |
| DK0477141T3 (en) | ||
| SE9203824D0 (en) | BENZOFURANY LIMIDAZOLE DERIVATIVES AND PROCESS FOR THE PREPARATION AND THERAPEUTICAL COMPOSITIONS CONTAINING THE SAME |