DK0516588T3 - Substituerede diaminophthalimider og analoger - Google Patents

Substituerede diaminophthalimider og analoger

Info

Publication number
DK0516588T3
DK0516588T3 DK92810385.2T DK92810385T DK0516588T3 DK 0516588 T3 DK0516588 T3 DK 0516588T3 DK 92810385 T DK92810385 T DK 92810385T DK 0516588 T3 DK0516588 T3 DK 0516588T3
Authority
DK
Denmark
Prior art keywords
analogues
diaminophthalimides
substituted
substituted diaminophthalimides
inhibition
Prior art date
Application number
DK92810385.2T
Other languages
Danish (da)
English (en)
Inventor
Peter Dr Traxler
Uwe Dr Trinks
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Application granted granted Critical
Publication of DK0516588T3 publication Critical patent/DK0516588T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Luminescent Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Stringed Musical Instruments (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Electrophonic Musical Instruments (AREA)
  • Pyridine Compounds (AREA)
DK92810385.2T 1991-05-30 1992-05-21 Substituerede diaminophthalimider og analoger DK0516588T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH160191 1991-05-30

Publications (1)

Publication Number Publication Date
DK0516588T3 true DK0516588T3 (da) 1994-08-15

Family

ID=4214234

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92810385.2T DK0516588T3 (da) 1991-05-30 1992-05-21 Substituerede diaminophthalimider og analoger

Country Status (25)

Country Link
EP (1) EP0516588B1 (enrdf_load_stackoverflow)
JP (1) JP2593273B2 (enrdf_load_stackoverflow)
KR (1) KR920021508A (enrdf_load_stackoverflow)
CN (1) CN1067052A (enrdf_load_stackoverflow)
AT (1) ATE108437T1 (enrdf_load_stackoverflow)
AU (1) AU653024B2 (enrdf_load_stackoverflow)
CA (1) CA2069857A1 (enrdf_load_stackoverflow)
CS (1) CS156792A3 (enrdf_load_stackoverflow)
CY (1) CY1979A (enrdf_load_stackoverflow)
DE (1) DE59200277D1 (enrdf_load_stackoverflow)
DK (1) DK0516588T3 (enrdf_load_stackoverflow)
ES (1) ES2056699T3 (enrdf_load_stackoverflow)
FI (1) FI100530B (enrdf_load_stackoverflow)
HK (1) HK214896A (enrdf_load_stackoverflow)
HU (1) HUT66655A (enrdf_load_stackoverflow)
IE (1) IE65772B1 (enrdf_load_stackoverflow)
IL (1) IL102038A0 (enrdf_load_stackoverflow)
MA (1) MA22540A1 (enrdf_load_stackoverflow)
MX (1) MX9202544A (enrdf_load_stackoverflow)
NO (1) NO178261C (enrdf_load_stackoverflow)
NZ (1) NZ242941A (enrdf_load_stackoverflow)
PL (1) PL170909B1 (enrdf_load_stackoverflow)
RU (1) RU2095349C1 (enrdf_load_stackoverflow)
TW (1) TW204341B (enrdf_load_stackoverflow)
ZA (1) ZA923940B (enrdf_load_stackoverflow)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5491144A (en) * 1991-05-30 1996-02-13 Ciba-Geigy Corporation Substituted diaminophthalimides and analogues
EP0600830A1 (de) * 1992-11-27 1994-06-08 Ciba-Geigy Ag Substituierte Derivate von Diaminophthalimid als Protein-Tyrosin-Kinase-Hemmer
EP0600831A1 (de) * 1992-11-27 1994-06-08 Ciba-Geigy Ag Phthalazinonderivate
ATE185698T1 (de) * 1993-06-25 1999-11-15 Main Camp Marketing Pty Ltd Therapeutisches agens
AU691815B2 (en) * 1993-06-25 1998-05-28 Main Camp Marketing Pty. Ltd. Therapeutic agent
GB9314893D0 (en) * 1993-07-19 1993-09-01 Zeneca Ltd Quinazoline derivatives
GB9325217D0 (en) * 1993-12-09 1994-02-09 Zeneca Ltd Pyrimidine derivatives
WO1995024190A2 (en) * 1994-03-07 1995-09-14 Sugen, Inc. Receptor tyrosine kinase inhibitors for inhibiting cell proliferative disorders and compositions thereof
GB9600545D0 (en) 1996-01-11 1996-03-13 Ciba Geigy Ag Compositions
EP1661566A3 (en) * 1996-08-05 2008-04-16 Myriad Genetics, Inc. Use of beta-sheet mimetics as protease and kinase inhibitors and as inhibitors of transcription factors
AU732174B2 (en) * 1996-08-05 2001-04-12 Myriad Genetics, Inc. Use of beta-sheet mimetics as protease and kinase inhibitors and as inhibitors of transcription factors
AU2002354114A1 (en) * 2001-11-30 2003-06-10 Matsushita Electric Industrial Co., Ltd. Bisimide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition
US20050182061A1 (en) * 2003-10-02 2005-08-18 Jeremy Green Phthalimide compounds useful as protein kinase inhibitors
WO2006047514A2 (en) * 2004-10-25 2006-05-04 Whitehead Institute For Biomedical Research Daph analogs and inhibition of protein aggregation
WO2006112479A1 (ja) * 2005-04-19 2006-10-26 Kyowa Hakko Kogyo Co., Ltd. 含窒素複素環化合物
DE102009031058A1 (de) * 2009-06-30 2011-01-27 Clariant International Ltd. Kontinuierliches Verfahren zur Herstellung von Amiden aromatischer Carbonsäuren
JP5934559B2 (ja) * 2012-04-05 2016-06-15 国立大学法人京都工芸繊維大学 発光材料および有機ｅｌ素子
CN105434432B (zh) * 2015-12-04 2018-11-13 中国科学院昆明植物研究所 N-羟基邻苯二甲酰亚胺类化合物在制备抗肿瘤药物中的应用
EP4367112A1 (en) 2021-07-09 2024-05-15 Plexium, Inc. Aryl compounds and pharmaceutical compositions that modulate ikzf2

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3857947A (en) * 1972-08-14 1974-12-31 Stauffer Chemical Co Fungicidal active phthalimides
GB1581073A (en) * 1976-09-08 1980-12-10 Campbell Chain Co Locking assembly
JPS60161968A (ja) * 1984-01-31 1985-08-23 Sankyo Co Ltd フタ−ルイミド誘導体及び農業用殺菌剤

Also Published As

Publication number Publication date
PL294701A1 (enrdf_load_stackoverflow) 1993-02-08
CN1067052A (zh) 1992-12-16
HK214896A (en) 1996-12-13
ES2056699T3 (es) 1994-10-01
FI100530B (fi) 1997-12-31
PL170909B1 (pl) 1997-02-28
KR920021508A (ko) 1992-12-18
NZ242941A (en) 1994-10-26
AU1705392A (en) 1992-12-03
NO922133L (no) 1992-12-01
CA2069857A1 (en) 1992-12-01
AU653024B2 (en) 1994-09-15
DE59200277D1 (de) 1994-08-18
RU2095349C1 (ru) 1997-11-10
IL102038A0 (en) 1992-12-30
NO922133D0 (no) 1992-05-29
MA22540A1 (fr) 1992-12-31
CY1979A (en) 1997-09-05
NO178261B (no) 1995-11-13
IE921770A1 (en) 1992-12-02
EP0516588A1 (de) 1992-12-02
FI922459L (fi) 1992-12-01
CS156792A3 (en) 1992-12-16
NO178261C (no) 1996-02-21
MX9202544A (es) 1992-11-01
EP0516588B1 (de) 1994-07-13
JP2593273B2 (ja) 1997-03-26
HUT66655A (en) 1994-12-28
FI922459A0 (fi) 1992-05-27
HU9201789D0 (en) 1992-08-28
TW204341B (enrdf_load_stackoverflow) 1993-04-21
JPH05163240A (ja) 1993-06-29
ZA923940B (en) 1993-11-15
IE65772B1 (en) 1995-11-15
ATE108437T1 (de) 1994-07-15

Similar Documents

Publication Publication Date Title
DK0516588T3 (da) Substituerede diaminophthalimider og analoger
NO921835L (no) Fremgangsmaate for fremstilling av amidinofenylalaninderivat samt anvendelse derav
BG92804A (bg) 4-бензоилизоксазолови производни
SE8300736D0 (sv) Novel pharmacologically active compounds
NZ244021A (en) Benzylthiazolidinedione derivatives, preparation and pharmaceutical compositions thereof
ATE161836T1 (de) 4-substituierte-2-deoxy-2,3-didehydro alpha-d- neuraminsäure antivirale derivate
DE59203976D1 (de) Hydantoinderivate.
DK147089A (da) Arylhydrazoner
DE68906609D1 (de) Dopamin-vorlaeufer.
NO303783B1 (no) Substituerte aminofosfonatderivater og farmas°ytiske preparater derav
ATE110365T1 (de) 2-alkyl-4-arylmethylaminochinoline, ihre verwendung und daraus hergestellte arzneimittel.
KR960703863A (ko) 암 치료용 신규 비스-나프탈이미드(New Bis-naphthalimides for the Treatment of Cancer)
ES2104682T3 (es) Fluor-compuestos.
NO306400B1 (no) N-substituerte azabicykloheptan-derivater, anvendelse derav og farmasöytisk preparat
DK319785D0 (da) Acetyleniske phenoxypropanolderivater
TR27833A (tr) Antelmintik'lerin uygulanmasina mahsus ''pour-on'' formülasyonu.
FI902901A0 (fi) Dibenzol/1,5/dioxocin-5-one-derivat, deras anvaendning i laekemedel och foerfarande foer deras framstaellning.
ES2098338T3 (es) Heteroarilmetilbencenos.
SE9203824D0 (sv) Benzofuranylimidazole derivatives a process for the preparation and therapeutical compositions containing the same
PL297368A1 (en) Novel derivatives of 2h-benzo (b) pyrane substituted with aryl or n-heteroaryl at position 4, method of obtaining them and their applications as well as preparation containing these compounds
DK0418990T3 (da) 13-brom- og 13,14-dibrom-ergoliner, deres fremstilling og anvendelse i lægemidler
NO903291D0 (no) Renin-hemmende aminooligohydroksy-derivater.
ES2073919T3 (es) Derivados de piperidina 1,3,4-trisubstituidos, su obtencion y empleo.
DK0580624T3 (da) Hidtil ukendte cytarabinderivater, fremstilling og anvendelse deraf
DK1105388T3 (da) N-substituerede azabicycloheptan-derivater, fremstilling og anvendelse heraf