NO990643D0 - Tienopyrimidiner - Google Patents

Tienopyrimidiner

Info

Publication number
NO990643D0
NO990643D0 NO990643A NO990643A NO990643D0 NO 990643 D0 NO990643 D0 NO 990643D0 NO 990643 A NO990643 A NO 990643A NO 990643 A NO990643 A NO 990643A NO 990643 D0 NO990643 D0 NO 990643D0
Authority
NO
Norway
Prior art keywords
thienopyrimidine
Prior art date
Application number
NO990643A
Other languages
English (en)
Norwegian (no)
Other versions
NO990643L (no
Inventor
Jonas Rochus
Pierre Schelling
Franz-Werner Kluxen
Maria Christadler
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of NO990643L publication Critical patent/NO990643L/no
Publication of NO990643D0 publication Critical patent/NO990643D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Gynecology & Obstetrics (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO990643A 1996-08-12 1999-02-11 Tienopyrimidiner NO990643D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19632423A DE19632423A1 (de) 1996-08-12 1996-08-12 Thienopyrimidine
PCT/EP1997/004139 WO1998006722A1 (de) 1996-08-12 1997-07-30 Thienopyrimidine

Publications (2)

Publication Number Publication Date
NO990643L NO990643L (no) 1999-02-11
NO990643D0 true NO990643D0 (no) 1999-02-11

Family

ID=7802392

Family Applications (1)

Application Number Title Priority Date Filing Date
NO990643A NO990643D0 (no) 1996-08-12 1999-02-11 Tienopyrimidiner

Country Status (28)

Country Link
US (1) US6110920A (cg-RX-API-DMAC7.html)
EP (1) EP0920431B1 (cg-RX-API-DMAC7.html)
JP (1) JP4405593B2 (cg-RX-API-DMAC7.html)
KR (1) KR100502271B1 (cg-RX-API-DMAC7.html)
CN (1) CN1081638C (cg-RX-API-DMAC7.html)
AR (1) AR009052A1 (cg-RX-API-DMAC7.html)
AT (1) ATE233265T1 (cg-RX-API-DMAC7.html)
AU (1) AU725227B2 (cg-RX-API-DMAC7.html)
BR (1) BR9711062A (cg-RX-API-DMAC7.html)
CA (1) CA2263561C (cg-RX-API-DMAC7.html)
CZ (1) CZ287772B6 (cg-RX-API-DMAC7.html)
DE (2) DE19632423A1 (cg-RX-API-DMAC7.html)
DK (1) DK0920431T3 (cg-RX-API-DMAC7.html)
ES (1) ES2191192T3 (cg-RX-API-DMAC7.html)
HU (1) HUP0001607A3 (cg-RX-API-DMAC7.html)
IL (1) IL128504A (cg-RX-API-DMAC7.html)
NO (1) NO990643D0 (cg-RX-API-DMAC7.html)
NZ (1) NZ334600A (cg-RX-API-DMAC7.html)
PL (1) PL190174B1 (cg-RX-API-DMAC7.html)
PT (1) PT920431E (cg-RX-API-DMAC7.html)
RU (1) RU2199541C2 (cg-RX-API-DMAC7.html)
SI (1) SI0920431T1 (cg-RX-API-DMAC7.html)
SK (1) SK282823B6 (cg-RX-API-DMAC7.html)
TR (1) TR199900308T2 (cg-RX-API-DMAC7.html)
TW (1) TW359672B (cg-RX-API-DMAC7.html)
UA (1) UA55421C2 (cg-RX-API-DMAC7.html)
WO (1) WO1998006722A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA977156B (cg-RX-API-DMAC7.html)

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DE19819023A1 (de) * 1998-04-29 1999-11-04 Merck Patent Gmbh Thienopyrimidine
US6974838B2 (en) 1998-08-24 2005-12-13 Sepracor Inc. Methods of treating or preventing pain using sibutramine metabolites
US6476078B2 (en) 1999-08-11 2002-11-05 Sepracor, Inc. Methods of using sibutramine metabolites in combination with a phosphodiesterase inhibitor to treat sexual dysfunction
US6339106B1 (en) 1999-08-11 2002-01-15 Sepracor, Inc. Methods and compositions for the treatment and prevention of sexual dysfunction
US6331571B1 (en) 1998-08-24 2001-12-18 Sepracor, Inc. Methods of treating and preventing attention deficit disorders
WO2000059912A1 (en) * 1999-03-30 2000-10-12 Nippon Soda Co., Ltd. Thienopyrimidine compounds and salts thereof and process for the preparation of the same
US6399826B1 (en) 1999-08-11 2002-06-04 Sepracor Inc. Salts of sibutramine metabolites, methods of making sibutramine metabolites and intermediates useful in the same, and methods of treating pain
DE19950647A1 (de) * 1999-10-21 2001-04-26 Merck Patent Gmbh Imidazolderivate als Phosphodiesterase VII-Hemmer
DE10031585A1 (de) * 2000-06-29 2002-01-10 Merck Patent Gmbh 2-Aminoalkyl-thieno[2,3-d]pyrimidine
CA2423981A1 (en) * 2000-09-29 2003-03-28 Kimiko Ichikawa Thienopyrimidine compounds and salts thereof and process for the preparation of the same
BR0206853A (pt) * 2001-02-02 2004-01-13 Merck Patent Ges Mit Beschroen Formulação farmacêutica compreendendo pirazolo[4,3-d]pirimidinas e antagonistas de receptor de endotelina ou tienopirimidinas e antagonistas de receptor de endotelina
WO2002083631A1 (en) 2001-04-13 2002-10-24 Sepracor Inc. Methods of preparing didesmethylsibutramine and other sibutramine derivatives
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US7153412B2 (en) 2001-12-28 2006-12-26 Kabushiki Kaisha Toyota Chuo Kenkyusho Electrodes, electrochemical elements, gas sensors, and gas measurement methods
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US7893101B2 (en) 2002-03-20 2011-02-22 Celgene Corporation Solid forms comprising (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions thereof, and uses thereof
US7208516B2 (en) 2002-03-20 2007-04-24 Celgene Corporation Methods of the treatment of psoriatic arthritis using (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione
US6962940B2 (en) 2002-03-20 2005-11-08 Celgene Corporation (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione: methods of using and compositions thereof
TW200410975A (en) * 2002-09-26 2004-07-01 Nihon Nohyaku Co Ltd New pesticide and method for using it, new substituted thienopyrimidine derivative, its intermediate, and method for producing it
GB0320300D0 (en) * 2003-08-29 2003-10-01 Cancer Rec Tech Ltd Pyrimidothiophene compounds
DE10351436A1 (de) * 2003-11-04 2005-06-09 Merck Patent Gmbh Verwendung von Thienopyrimidinen
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US9603848B2 (en) 2007-06-08 2017-03-28 Senomyx, Inc. Modulation of chemosensory receptors and ligands associated therewith
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KR101523126B1 (ko) 2008-07-31 2015-05-26 세노믹스, 인코포레이티드 단맛 향상제의 제조 방법 및 중간체
ES2439291T3 (es) 2008-09-02 2014-01-22 Janssen Pharmaceuticals, Inc. Derivados de 3-azabiciclo[3.1.0]hexilo como moduladores de receptores de glutamato metabotrópicos
JP5656848B2 (ja) 2008-10-16 2015-01-21 ジャンセン ファーマシューティカルズ， インコーポレイテッド． 代謝型グルタミン酸受容体モジュレーターとしてのインドールおよびベンゾモルホリンの誘導体
EP2373649B1 (en) 2008-11-28 2013-01-23 Janssen Pharmaceuticals, Inc. Indole and benzoxazine derivatives as modulators of metabotropic glutamate receptors
WO2010130424A1 (en) 2009-05-12 2010-11-18 Ortho-Mcneil-Janssen Pharmaceuticals, Inc 1,2,3-triazolo [4,3-a] pyridine derivatives and their use for the treatment or prevention of neurological and psychiatric disorders
SG176018A1 (en) 2009-05-12 2011-12-29 Janssen Pharmaceuticals Inc 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
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KR20200036063A (ko) 2014-01-21 2020-04-06 얀센 파마슈티카 엔.브이. 대사 조절형 글루탐산 작동성 수용체 제2아형의 양성 알로스테릭 조절제 또는 오르토스테릭 작동제를 포함하는 조합 및 그 용도
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ES2749433T3 (es) 2014-06-23 2020-03-20 Celgene Corp Apremilast para el tratamiento de una enfermedad hepática o una anomalía de la función hepática
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Family Cites Families (5)

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GB1570494A (en) * 1975-11-28 1980-07-02 Ici Ltd Thienopyrimidine derivatives and their use as pesticides
US4196207A (en) * 1977-05-23 1980-04-01 Ici Australia Limited Process for controlling eradicating or preventing infestations of animals by Ixodid ticks
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IL112249A (en) * 1994-01-25 2001-11-25 Warner Lambert Co Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds
US5869486A (en) * 1995-02-24 1999-02-09 Ono Pharmaceutical Co., Ltd. Fused pyrimidines and pyriazines as pharmaceutical compounds

Also Published As

Publication number Publication date
NO990643L (no) 1999-02-11
HUP0001607A3 (en) 2002-09-30
IL128504A (en) 2003-01-12
CZ44899A3 (cs) 1999-05-12
JP4405593B2 (ja) 2010-01-27
HUP0001607A2 (hu) 2000-10-28
CA2263561C (en) 2007-02-20
EP0920431A1 (de) 1999-06-09
JP2000516223A (ja) 2000-12-05
EP0920431B1 (de) 2003-02-26
BR9711062A (pt) 1999-08-17
PT920431E (pt) 2003-07-31
CN1227560A (zh) 1999-09-01
SK282823B6 (sk) 2002-12-03
WO1998006722A1 (de) 1998-02-19
AU725227B2 (en) 2000-10-12
TW359672B (en) 1999-06-01
PL190174B1 (pl) 2005-11-30
IL128504A0 (en) 2000-01-31
NZ334600A (en) 2000-07-28
PL331538A1 (en) 1999-07-19
UA55421C2 (uk) 2003-04-15
ATE233265T1 (de) 2003-03-15
CN1081638C (zh) 2002-03-27
AU4203597A (en) 1998-03-06
ZA977156B (en) 1998-02-19
DK0920431T3 (da) 2003-06-02
SI0920431T1 (en) 2003-08-31
TR199900308T2 (xx) 1999-04-21
SK16499A3 (en) 1999-06-11
DE19632423A1 (de) 1998-02-19
AR009052A1 (es) 2000-03-08
DE59709404D1 (en) 2003-04-03
HK1021731A1 (en) 2000-06-30
KR20000029932A (ko) 2000-05-25
ES2191192T3 (es) 2003-09-01
RU2199541C2 (ru) 2003-02-27
CA2263561A1 (en) 1998-02-19
CZ287772B6 (en) 2001-01-17
US6110920A (en) 2000-08-29
KR100502271B1 (ko) 2005-07-22

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