NO984084D0 - 4-Amino-pyrimidin-derivater, medikamenter inneholdende disse forbindelser, deres anvendelse og fremgangsmÕte ved fremstilling derav - Google Patents
4-Amino-pyrimidin-derivater, medikamenter inneholdende disse forbindelser, deres anvendelse og fremgangsmÕte ved fremstilling deravInfo
- Publication number
- NO984084D0 NO984084D0 NO984084A NO984084A NO984084D0 NO 984084 D0 NO984084 D0 NO 984084D0 NO 984084 A NO984084 A NO 984084A NO 984084 A NO984084 A NO 984084A NO 984084 D0 NO984084 D0 NO 984084D0
- Authority
- NO
- Norway
- Prior art keywords
- amino
- compounds
- preparation
- pyrimidine derivatives
- medicaments containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE1996108631 DE19608631A1 (de) | 1996-03-06 | 1996-03-06 | 4-Amino-pyrimidin-Derivate, diese Verbindungen enthaltende Arnzeimittel, deren Verwendung und Verfahren zu ihrer Herstellung |
| DE19629652A DE19629652A1 (de) | 1996-03-06 | 1996-07-23 | 4-Amino-pyrimidin-Derivate, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung |
| PCT/EP1997/001057 WO1997032881A1 (fr) | 1996-03-06 | 1997-03-03 | Derives de 4-amino-pyrimidine, medicaments contenant ces composes, leur utilisation et leur procede de production |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO984084L NO984084L (no) | 1998-09-04 |
| NO984084D0 true NO984084D0 (no) | 1998-09-04 |
Family
ID=26023531
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO984084A NO984084D0 (no) | 1996-03-06 | 1998-09-04 | 4-Amino-pyrimidin-derivater, medikamenter inneholdende disse forbindelser, deres anvendelse og fremgangsmÕte ved fremstilling derav |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0885226A1 (fr) |
| JP (1) | JP2000506847A (fr) |
| KR (1) | KR19990087550A (fr) |
| CN (1) | CN1212695A (fr) |
| AU (1) | AU710274B2 (fr) |
| BG (1) | BG102708A (fr) |
| BR (1) | BR9708312A (fr) |
| CA (1) | CA2243994A1 (fr) |
| CZ (1) | CZ281798A3 (fr) |
| DE (1) | DE19629652A1 (fr) |
| EE (1) | EE9800277A (fr) |
| HU (1) | HUP9901820A3 (fr) |
| IL (1) | IL125404A0 (fr) |
| NO (1) | NO984084D0 (fr) |
| NZ (1) | NZ331546A (fr) |
| PL (1) | PL328771A1 (fr) |
| SK (1) | SK120598A3 (fr) |
| TR (1) | TR199801749T2 (fr) |
| WO (1) | WO1997032881A1 (fr) |
Families Citing this family (81)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0880508B1 (fr) | 1996-02-13 | 2003-04-16 | AstraZeneca AB | Derives de la quinazoline utilises comme inhibiteurs du vegf |
| IL125954A (en) | 1996-03-05 | 2003-06-24 | Zeneca Ltd | Quinazoline derivatives, processes for their preparation, pharmaceutical compositions containing them and use thereof in the manufacture of medicaments having an antiangiogenic and/or vascular permeability reducing effect |
| EP1396489A1 (fr) * | 1999-01-27 | 2004-03-10 | Pfizer Products Inc. | Composés hétéroaromatiques bicycliques a activité anticancereuse |
| UA71945C2 (en) * | 1999-01-27 | 2005-01-17 | Pfizer Prod Inc | Substituted bicyclic derivatives being used as anticancer agents |
| PT1244647E (pt) | 1999-11-05 | 2006-10-31 | Astrazeneca Ab | Derivados de quinazolina como inibidores de vegf |
| CA2530023A1 (fr) | 2003-06-24 | 2004-12-29 | Neurosearch A/S | Nouveaux derives de 8-aza-bicyclo[3.2.1]octane et utilisation en tant qu'inhibiteurs de la reabsorption des neurotransmetteurs monoamine |
| WO2006088836A2 (fr) * | 2005-02-16 | 2006-08-24 | Schering Corporation | Piperazine-piperidines a activite antagoniste cxcr3 |
| MX2011004824A (es) | 2008-11-07 | 2012-01-12 | Triact Therapeutics Inc | Uso de derivados de butano catecólico en terapia contra el cáncer. |
| CN102216299B (zh) * | 2008-12-01 | 2015-02-11 | 默克专利有限公司 | 作为自体毒素抑制剂的2,5-二氨基取代的吡啶并[4,3-d]嘧啶化合物 |
| US20120189641A1 (en) | 2009-02-25 | 2012-07-26 | OSI Pharmaceuticals, LLC | Combination anti-cancer therapy |
| US20110171124A1 (en) | 2009-02-26 | 2011-07-14 | Osi Pharmaceuticals, Inc. | In situ methods for monitoring the EMT status of tumor cells in vivo |
| WO2010099138A2 (fr) | 2009-02-27 | 2010-09-02 | Osi Pharmaceuticals, Inc. | Procédés pour l'identification d'agents qui inhibent les cellules tumorales de type mésenchymateuses ou leur formation |
| JP2012519282A (ja) | 2009-02-27 | 2012-08-23 | オーエスアイ・ファーマシューティカルズ，エルエルシー | 間葉様腫瘍細胞またはその生成を阻害する薬剤を同定するための方法 |
| US8642834B2 (en) | 2009-02-27 | 2014-02-04 | OSI Pharmaceuticals, LLC | Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation |
| US20120064072A1 (en) | 2009-03-18 | 2012-03-15 | Maryland Franklin | Combination Cancer Therapy Comprising Administration of an EGFR Inhibitor and an IGF-1R Inhibitor |
| CA2780875A1 (fr) | 2009-11-13 | 2011-05-19 | Pangaea Biotech, S.L. | Biomarqueurs moleculaires pour predire une reponse a des inhibiteurs de tyrosine kinase dans le cancer du poumon |
| EP2468883A1 (fr) | 2010-12-22 | 2012-06-27 | Pangaea Biotech S.L. | Biomarqueurs moléculaires pour la prédiction de la réponse aux inhibiteurs de la tyrosine kinase dans le cancer du poumon |
| US9134297B2 (en) | 2011-01-11 | 2015-09-15 | Icahn School Of Medicine At Mount Sinai | Method and compositions for treating cancer and related methods |
| EP2492688A1 (fr) | 2011-02-23 | 2012-08-29 | Pangaea Biotech, S.A. | Biomarqueurs moléculaires pour la prédiction de la réponse à un traitement antitumoral dans le cancer du poumon |
| WO2012129145A1 (fr) | 2011-03-18 | 2012-09-27 | OSI Pharmaceuticals, LLC | Polythérapie du cancer du poumon non à petites cellules (nsclc) |
| US9896730B2 (en) | 2011-04-25 | 2018-02-20 | OSI Pharmaceuticals, LLC | Use of EMT gene signatures in cancer drug discovery, diagnostics, and treatment |
| CA2845179A1 (fr) | 2011-08-31 | 2013-03-07 | Genentech, Inc. | Marqueurs de diagnostic |
| AU2012321248A1 (en) | 2011-09-30 | 2014-04-24 | Genentech, Inc. | Diagnostic methylation markers of epithelial or mesenchymal phenotype and response to EGFR kinase inhibitor in tumours or tumour cells |
| WO2013152252A1 (fr) | 2012-04-06 | 2013-10-10 | OSI Pharmaceuticals, LLC | Polythérapie antinéoplasique |
| WO2013190089A1 (fr) | 2012-06-21 | 2013-12-27 | Pangaea Biotech, S.L. | Biomarqueurs moléculaires permettant de prédire l'issue dans le cancer du poumon |
| CA2941010A1 (fr) | 2013-02-26 | 2014-09-04 | Triact Therapeutics, Inc. | Cancerotherapie |
| EP2976085A1 (fr) | 2013-03-21 | 2016-01-27 | INSERM - Institut National de la Santé et de la Recherche Médicale | Méthode et composition pharmaceutique pour l'utilisation dans le traitement de maladies hépatiques chroniques associées à une faible expression d'hepcidine |
| CA2923667A1 (fr) | 2013-09-09 | 2015-03-12 | Triact Therapeutics, Inc. | Traitement du cancer |
| WO2015156674A2 (fr) | 2014-04-10 | 2015-10-15 | Stichting Het Nederlands Kanker Instituut | Méthode de traitement du cancer |
| EP3237638B1 (fr) | 2014-12-24 | 2020-01-15 | F.Hoffmann-La Roche Ag | Méthodes de traitement, de diagnostic et de pronostic du cancer de la vessie |
| MX2019007643A (es) | 2016-12-22 | 2019-09-09 | Amgen Inc | Benzoisotiazol, isotiazolo[3,4-b]piridina, quinazolina, ftalazina, pirido[2,3-d]piridazina y derivados de pirido[2,3-d]pirimidina como inhibirores de kras g12c para tratar el cancer de pulmon, pancreatico o colorrectal. |
| JOP20190272A1 (ar) | 2017-05-22 | 2019-11-21 | Amgen Inc | مثبطات kras g12c وطرق لاستخدامها |
| EP4403175A3 (fr) | 2017-09-08 | 2024-10-02 | Amgen Inc. | Inhibiteurs de kras g12c et leurs procédés d'utilisation |
| AU2019262599B2 (en) | 2018-05-04 | 2023-10-12 | Amgen Inc. | KRAS G12C inhibitors and methods of using the same |
| WO2019213516A1 (fr) | 2018-05-04 | 2019-11-07 | Amgen Inc. | Inhibiteurs de kras g12c et leurs procédés d'utilisation |
| EP3790886B1 (fr) | 2018-05-10 | 2024-06-26 | Amgen Inc. | Inhibiteurs du kras g12c pour le traitement du cancer |
| AU2019278998B2 (en) | 2018-06-01 | 2023-11-09 | Amgen Inc. | KRAS G12C inhibitors and methods of using the same |
| CA3099799A1 (fr) | 2018-06-11 | 2019-12-19 | Amgen Inc. | Inhibiteurs de kras g12c pour le traitement du cancer |
| US11285156B2 (en) | 2018-06-12 | 2022-03-29 | Amgen Inc. | Substituted piperazines as KRAS G12C inhibitors |
| JP2022512584A (ja) | 2018-10-04 | 2022-02-07 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | 角皮症を処置するためのｅｇｆｒインヒビター |
| JP7516029B2 (ja) | 2018-11-16 | 2024-07-16 | アムジエン・インコーポレーテツド | Ｋｒａｓ ｇ１２ｃ阻害剤化合物の重要な中間体の改良合成法 |
| US11053226B2 (en) | 2018-11-19 | 2021-07-06 | Amgen Inc. | KRAS G12C inhibitors and methods of using the same |
| JP7377679B2 (ja) | 2018-11-19 | 2023-11-10 | アムジエン・インコーポレーテツド | がん治療のためのｋｒａｓｇ１２ｃ阻害剤及び１種以上の薬学的に活性な追加の薬剤を含む併用療法 |
| CA3123227A1 (fr) | 2018-12-20 | 2020-06-25 | Amgen Inc. | Amides d'heteroaryle utiles en tant qu'inhibiteurs de kif18a |
| WO2020132651A1 (fr) | 2018-12-20 | 2020-06-25 | Amgen Inc. | Inhibiteurs de kif18a |
| MA54543A (fr) | 2018-12-20 | 2022-03-30 | Amgen Inc | Inhibiteurs de kif18a |
| MX2021007157A (es) | 2018-12-20 | 2021-08-16 | Amgen Inc | Heteroarilamidas utiles como inhibidores de kif18a. |
| AU2020232616A1 (en) | 2019-03-01 | 2021-09-09 | Revolution Medicines, Inc. | Bicyclic heterocyclyl compounds and uses thereof |
| CN113767100A (zh) | 2019-03-01 | 2021-12-07 | 锐新医药公司 | 双环杂芳基化合物及其用途 |
| EP3738593A1 (fr) | 2019-05-14 | 2020-11-18 | Amgen, Inc | Dosage d'inhibiteur de kras pour le traitement de cancers |
| KR20220011670A (ko) | 2019-05-21 | 2022-01-28 | 암젠 인크 | 고체 상태 형태 |
| AU2020326627A1 (en) | 2019-08-02 | 2022-03-17 | Amgen Inc. | KIF18A inhibitors |
| US20220281843A1 (en) | 2019-08-02 | 2022-09-08 | Amgen Inc. | Kif18a inhibitors |
| US20240254100A1 (en) | 2019-08-02 | 2024-08-01 | Amgen Inc. | Kif18a inhibitors |
| US20220372018A1 (en) | 2019-08-02 | 2022-11-24 | Amgen Inc. | Kif18a inhibitors |
| JP2022552873A (ja) | 2019-10-24 | 2022-12-20 | アムジエン・インコーポレーテツド | がんの治療におけるｋｒａｓ ｇ１２ｃ及びｋｒａｓ ｇ１２ｄ阻害剤として有用なピリドピリミジン誘導体 |
| US11739074B2 (en) | 2019-11-04 | 2023-08-29 | Revolution Medicines, Inc. | Ras inhibitors |
| AU2020379734A1 (en) | 2019-11-04 | 2022-05-05 | Revolution Medicines, Inc. | Ras inhibitors |
| TW202132314A (zh) | 2019-11-04 | 2021-09-01 | 美商銳新醫藥公司 | Ｒａｓ抑制劑 |
| JP2023500328A (ja) | 2019-11-08 | 2023-01-05 | レボリューション メディシンズ インコーポレイテッド | 二環式ヘテロアリール化合物及びその使用 |
| US20230192681A1 (en) | 2019-11-14 | 2023-06-22 | Amgen Inc. | Improved synthesis of kras g12c inhibitor compound |
| AR120456A1 (es) | 2019-11-14 | 2022-02-16 | Amgen Inc | Síntesis mejorada del compuesto inhibidor de g12c de kras |
| WO2021108683A1 (fr) | 2019-11-27 | 2021-06-03 | Revolution Medicines, Inc. | Inhibiteurs de ras covalents et leurs utilisations |
| JP2023509701A (ja) | 2020-01-07 | 2023-03-09 | レヴォリューション・メディスンズ，インコーポレイテッド | Ｓｈｐ２阻害剤投薬およびがんを処置する方法 |
| CN115916194A (zh) | 2020-06-18 | 2023-04-04 | 锐新医药公司 | 用于延迟、预防和治疗针对ras抑制剂的获得性抗性的方法 |
| WO2022060583A1 (fr) | 2020-09-03 | 2022-03-24 | Revolution Medicines, Inc. | Utilisation d'inhibiteurs de sos1 pour traiter des malignités à mutations de shp2 |
| AU2021345111A1 (en) | 2020-09-15 | 2023-04-06 | Revolution Medicines, Inc. | Indole derivatives as Ras inhibitors in the treatment of cancer |
| AU2021409816A1 (en) | 2020-12-22 | 2023-07-06 | Qilu Regor Therapeutics Inc. | Sos1 inhibitors and uses thereof |
| PE20240327A1 (es) | 2021-04-13 | 2024-02-22 | Nuvalent Inc | Heterociclos con sustitucion amino para tratar canceres con mutaciones de egfr |
| WO2022235864A1 (fr) | 2021-05-05 | 2022-11-10 | Revolution Medicines, Inc. | Inhibiteurs de ras |
| CN117616031A (zh) | 2021-05-05 | 2024-02-27 | 锐新医药公司 | 用于治疗癌症的ras抑制剂 |
| WO2022235866A1 (fr) | 2021-05-05 | 2022-11-10 | Revolution Medicines, Inc. | Inhibiteurs de ras covalents et leurs utilisations |
| AR127308A1 (es) | 2021-10-08 | 2024-01-10 | Revolution Medicines Inc | Inhibidores ras |
| WO2023114954A1 (fr) | 2021-12-17 | 2023-06-22 | Genzyme Corporation | Composés pyrazolopyrazine utilisés comme inhibiteurs de la shp2 |
| EP4227307A1 (fr) | 2022-02-11 | 2023-08-16 | Genzyme Corporation | Composés pyrazolopyrazine en tant qu'inhibiteurs de shp2 |
| WO2023172940A1 (fr) | 2022-03-08 | 2023-09-14 | Revolution Medicines, Inc. | Méthodes de traitement du cancer du poumon réfractaire immunitaire |
| WO2023240263A1 (fr) | 2022-06-10 | 2023-12-14 | Revolution Medicines, Inc. | Inhibiteurs de ras macrocycliques |
| WO2024081916A1 (fr) | 2022-10-14 | 2024-04-18 | Black Diamond Therapeutics, Inc. | Méthodes de traitement de cancers à l'aide de dérivés d'isoquinoline ou de 6-aza-quinoléine |
| WO2024206858A1 (fr) | 2023-03-30 | 2024-10-03 | Revolution Medicines, Inc. | Compositions pour induire une hydrolyse de ras gtp et leurs utilisations |
| WO2024211663A1 (fr) | 2023-04-07 | 2024-10-10 | Revolution Medicines, Inc. | Composés macrocycliques condensés en tant qu'inhibiteurs de ras |
| WO2024211712A1 (fr) | 2023-04-07 | 2024-10-10 | Revolution Medicines, Inc. | Composés macrocycliques condensés en tant qu'inhibiteurs de ras |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL112249A (en) * | 1994-01-25 | 2001-11-25 | Warner Lambert Co | Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds |
| DE4431867A1 (de) * | 1994-09-07 | 1996-03-14 | Thomae Gmbh Dr K | Pyrimido[5,4-d]pyrimidine, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung |
-
1996
- 1996-07-23 DE DE19629652A patent/DE19629652A1/de not_active Ceased
-
1997
- 1997-03-03 IL IL12540497A patent/IL125404A0/xx unknown
- 1997-03-03 EP EP97907066A patent/EP0885226A1/fr not_active Ceased
- 1997-03-03 HU HU9901820A patent/HUP9901820A3/hu unknown
- 1997-03-03 CZ CZ982817A patent/CZ281798A3/cs unknown
- 1997-03-03 CN CN97192787A patent/CN1212695A/zh active Pending
- 1997-03-03 PL PL97328771A patent/PL328771A1/xx unknown
- 1997-03-03 NZ NZ331546A patent/NZ331546A/xx unknown
- 1997-03-03 KR KR1019980706987A patent/KR19990087550A/ko not_active Application Discontinuation
- 1997-03-03 BR BR9708312A patent/BR9708312A/pt not_active IP Right Cessation
- 1997-03-03 SK SK1205-98A patent/SK120598A3/sk unknown
- 1997-03-03 AU AU19251/97A patent/AU710274B2/en not_active Ceased
- 1997-03-03 CA CA002243994A patent/CA2243994A1/fr not_active Abandoned
- 1997-03-03 WO PCT/EP1997/001057 patent/WO1997032881A1/fr not_active Application Discontinuation
- 1997-03-03 TR TR1998/01749T patent/TR199801749T2/xx unknown
- 1997-03-03 EE EE9800277A patent/EE9800277A/xx unknown
- 1997-03-03 JP JP9531444A patent/JP2000506847A/ja active Pending
-
1998
- 1998-08-20 BG BG102708A patent/BG102708A/xx unknown
- 1998-09-04 NO NO984084A patent/NO984084D0/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ331546A (en) | 2000-03-27 |
| JP2000506847A (ja) | 2000-06-06 |
| AU710274B2 (en) | 1999-09-16 |
| HUP9901820A2 (hu) | 1999-09-28 |
| EE9800277A (et) | 1999-02-15 |
| CN1212695A (zh) | 1999-03-31 |
| CZ281798A3 (cs) | 1999-02-17 |
| BG102708A (en) | 1999-09-30 |
| CA2243994A1 (fr) | 1997-09-12 |
| KR19990087550A (ko) | 1999-12-27 |
| IL125404A0 (en) | 1999-03-12 |
| NO984084L (no) | 1998-09-04 |
| EP0885226A1 (fr) | 1998-12-23 |
| BR9708312A (pt) | 1999-08-03 |
| WO1997032881A1 (fr) | 1997-09-12 |
| AU1925197A (en) | 1997-09-22 |
| HUP9901820A3 (en) | 2001-10-29 |
| PL328771A1 (en) | 1999-02-15 |
| TR199801749T2 (xx) | 1998-12-21 |
| SK120598A3 (en) | 1999-06-11 |
| DE19629652A1 (de) | 1998-01-29 |
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| NO973479L (no) | Substituerte heterosykliske forbindelser, fremgangsmåte for fremstilling og farmasöytiske blandinger inneholdende samme | |
| NO20032726D0 (no) | Kinazolinderivater, medikamenter inneholdende disse forbindelser, deres anvendelse og fremgangsmåte for fremstilling derav | |
| EE04399B1 (et) | Spiroasabitsüklilised heterotsüklilised ühendid, nende valmistamise protsess, neid sisaldavad ravimkoostised ja nende kasutamine ravis | |
| NO954239D0 (no) | Heterocykliske forbindelser og deres fremstilling og anvendelse | |
| DK32286D0 (da) | Fremgangsmaade til fremstilling af 1-substituerede aryl-1,4-dihydro-4-oxanaphthyridinderivater, mellemprodukter til brug ved fremgangsmaaden og fremgangsmaade til fremstilling af disse | |
| NO306401B1 (no) | Oksazolidindionderivater, farmasöytisk preparat inneholdende slike derivater, og deres anvendelse | |
| NO984081D0 (no) | Pyrimido£5,4-d|pyrimidiner, medikamenter inneholdende disse forbindelser, deres anvendelse og fremgangsmÕte for fremtilling derav | |
| DK1112251T3 (da) | Azetidinderivater, deres fremstilling og medikamenter indeholdende disse derivater | |
| NO20006251D0 (no) | Benzotiepin-1,1-dioksidderivater, fremgangsmåte for deres fremstilling, legemidler som inneholder disse forbindelsene og deres anvendelse | |
| NO961071D0 (no) | Kjemiske forbindelser, deres fremstilling og anvendelse | |
| NO20003067D0 (no) | Antipicornavirus-forbindelser og fremgangsmÕter for deres anvendelse og fremstilling | |
| NO980720D0 (no) | Pyridazin-3-on-derivater, deres anvendelse og mellomprodukter for deres fremstilling | |
| NO20000294D0 (no) | Derivater av acylpiperazinylpyrimidiner, deres fremstilling og anvendelse som legemidler | |
| NO20003070L (no) | Substituert tiazolidinderivat, fremgangsmÕte for fremstilling og anvendelse derav | |
| DK394489A (da) | I para-stillingen heterocyclisk substituerede n-phenylamidforbindelser, mellemprodukter ved deres fremstilling, farmaceutiske praeparater indeholdende forbindelserne og anvendelse af forbindelserne til fremstilling af antiarytmiske laegemidler | |
| DK1117661T3 (da) | Propanolaminderivater substitueret med heterocycliske grupper, fremgangsmåde til deres fremstilling, farmaceutiske præparater indeholdende disse forbindelser og deres anvendelse | |
| DK155292D0 (da) | Kemiske forbindelser, deres fremstilling og anvendelse | |
| NO985248L (no) | Indolylpyrrolydenmetylpyrrolderivater og fremgangsmÕte for deres fremstilli | |
| DK0838469T3 (da) | 10,13,15-trioxatricyclo(9.2.1 9.6)-pentadecanon-derivater, fremgangsmåde til deres fremstilling og lægemidler indeholdende disse forbindelser | |
| DK60593D0 (da) | Kemiske forbindelser, deres fremstilling og anvendelse |