NZ331546A - 4-phenylamino pyridopyrimidine derivatives, medicaments containing these compounds, their use and process for their production - Google Patents

4-phenylamino pyridopyrimidine derivatives, medicaments containing these compounds, their use and process for their production

Info

Publication number
NZ331546A
NZ331546A NZ331546A NZ33154697A NZ331546A NZ 331546 A NZ331546 A NZ 331546A NZ 331546 A NZ331546 A NZ 331546A NZ 33154697 A NZ33154697 A NZ 33154697A NZ 331546 A NZ331546 A NZ 331546A
Authority
NZ
New Zealand
Prior art keywords
crc
phenylamino
production
compounds
pyridopyrimidine derivatives
Prior art date
Application number
NZ331546A
Inventor
Frank Himmelsbach
Georg Dahmann
Ruden Thomas Von
Thomas Metz
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE1996108631 external-priority patent/DE19608631A1/en
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of NZ331546A publication Critical patent/NZ331546A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The present invention relates to 4-phenylamino pyridopyrimidine derivatives of the formula shown, where Ra is H or CH3, Rb is optionally substituted phenyl or phenylalkyl, A and B together are a bridge selected from -N=CRc-CH=CH-, -CH=N-CRc=CH-, -CH=CRc-N=CH-, -CH-=CH-CRc=N- or -CH=N-CRc=N-, and their tautomers, stereoisomers and salts, especially their physiologically acceptable salts with inorganic or organic acids or bases, having valuable pharmacological properties, especially an inhibitory effect on signal transduction produced by tyrosine kinases, their use in the treatment of disorders, especially tumours, and their production.
NZ331546A 1996-03-06 1997-03-03 4-phenylamino pyridopyrimidine derivatives, medicaments containing these compounds, their use and process for their production NZ331546A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE1996108631 DE19608631A1 (en) 1996-03-06 1996-03-06 New (heterocyclyl- pyrimidino or -pyrido)fused pyrimidine derivatives
DE19629652A DE19629652A1 (en) 1996-03-06 1996-07-23 4-Amino-pyrimidine derivatives, medicaments containing these compounds, their use and processes for their preparation
PCT/EP1997/001057 WO1997032881A1 (en) 1996-03-06 1997-03-03 4-amino pyrimidine derivates, medicaments containing these compounds, their use and process for their production

Publications (1)

Publication Number Publication Date
NZ331546A true NZ331546A (en) 2000-03-27

Family

ID=26023531

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ331546A NZ331546A (en) 1996-03-06 1997-03-03 4-phenylamino pyridopyrimidine derivatives, medicaments containing these compounds, their use and process for their production

Country Status (19)

Country Link
EP (1) EP0885226A1 (en)
JP (1) JP2000506847A (en)
KR (1) KR19990087550A (en)
CN (1) CN1212695A (en)
AU (1) AU710274B2 (en)
BG (1) BG102708A (en)
BR (1) BR9708312A (en)
CA (1) CA2243994A1 (en)
CZ (1) CZ281798A3 (en)
DE (1) DE19629652A1 (en)
EE (1) EE9800277A (en)
HU (1) HUP9901820A3 (en)
IL (1) IL125404A0 (en)
NO (1) NO984084D0 (en)
NZ (1) NZ331546A (en)
PL (1) PL328771A1 (en)
SK (1) SK120598A3 (en)
TR (1) TR199801749T2 (en)
WO (1) WO1997032881A1 (en)

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Also Published As

Publication number Publication date
HUP9901820A3 (en) 2001-10-29
EE9800277A (en) 1999-02-15
AU1925197A (en) 1997-09-22
WO1997032881A1 (en) 1997-09-12
CZ281798A3 (en) 1999-02-17
BR9708312A (en) 1999-08-03
CA2243994A1 (en) 1997-09-12
KR19990087550A (en) 1999-12-27
BG102708A (en) 1999-09-30
NO984084L (en) 1998-09-04
DE19629652A1 (en) 1998-01-29
EP0885226A1 (en) 1998-12-23
TR199801749T2 (en) 1998-12-21
SK120598A3 (en) 1999-06-11
HUP9901820A2 (en) 1999-09-28
NO984084D0 (en) 1998-09-04
PL328771A1 (en) 1999-02-15
CN1212695A (en) 1999-03-31
AU710274B2 (en) 1999-09-16
JP2000506847A (en) 2000-06-06
IL125404A0 (en) 1999-03-12

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