NO975663L - Semikarbazoner med CNS aktivitet og farmasöytiske preparater inneholdende de samme - Google Patents

Semikarbazoner med CNS aktivitet og farmasöytiske preparater inneholdende de samme

Info

Publication number
NO975663L
NO975663L NO975663A NO975663A NO975663L NO 975663 L NO975663 L NO 975663L NO 975663 A NO975663 A NO 975663A NO 975663 A NO975663 A NO 975663A NO 975663 L NO975663 L NO 975663L
Authority
NO
Norway
Prior art keywords
same
semicarbazones
pharmaceutical preparations
preparations containing
cns activity
Prior art date
Application number
NO975663A
Other languages
English (en)
Other versions
NO975663D0 (no
NO310655B1 (no
Inventor
Jonathan Richard Dimmock
Ramanan Narayan Puthucode
Original Assignee
Univ Saskatchewan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Saskatchewan filed Critical Univ Saskatchewan
Publication of NO975663D0 publication Critical patent/NO975663D0/no
Publication of NO975663L publication Critical patent/NO975663L/no
Publication of NO310655B1 publication Critical patent/NO310655B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/06—Compounds containing any of the groups, e.g. semicarbazides
    • C07C281/08—Compounds containing any of the groups, e.g. semicarbazides the other nitrogen atom being further doubly-bound to a carbon atom, e.g. semicarbazones
    • C07C281/14—Compounds containing any of the groups, e.g. semicarbazides the other nitrogen atom being further doubly-bound to a carbon atom, e.g. semicarbazones the carbon atom being further bound to a carbon atom of a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A61K31/175—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine having the group, >N—C(O)—N=N— or, e.g. carbonohydrazides, carbazones, semicarbazides, semicarbazones; Thioanalogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
NO19975663A 1995-06-07 1997-12-05 Forbindelse, preparat omfattende denne, fremgangsmåte for fremstilling av forbindelsen samt anvendelse NO310655B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/475,313 US5741818A (en) 1995-06-07 1995-06-07 Semicarbazones having CNS activity and pharmaceutical preparations containing same
PCT/CA1996/000380 WO1996040628A1 (en) 1995-06-07 1996-06-07 Semicarbazones having cns activity and pharmaceutical preparations containing same

Publications (3)

Publication Number Publication Date
NO975663D0 NO975663D0 (no) 1997-12-05
NO975663L true NO975663L (no) 1998-02-09
NO310655B1 NO310655B1 (no) 2001-08-06

Family

ID=23887035

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19975663A NO310655B1 (no) 1995-06-07 1997-12-05 Forbindelse, preparat omfattende denne, fremgangsmåte for fremstilling av forbindelsen samt anvendelse

Country Status (24)

Country Link
US (2) US5741818A (no)
EP (1) EP0836591B1 (no)
JP (1) JPH11506109A (no)
KR (1) KR19990022408A (no)
CN (1) CN1062263C (no)
AT (1) ATE206110T1 (no)
AU (1) AU715897B2 (no)
BR (1) BR9609408A (no)
CA (1) CA2223935A1 (no)
CZ (1) CZ387497A3 (no)
DE (1) DE69615558T2 (no)
DK (1) DK0836591T3 (no)
ES (1) ES2164889T3 (no)
FI (1) FI974447A (no)
GE (1) GEP20012414B (no)
HU (1) HUP9802637A3 (no)
IL (1) IL122350A0 (no)
NO (1) NO310655B1 (no)
NZ (1) NZ309707A (no)
PL (1) PL184048B1 (no)
PT (1) PT836591E (no)
RU (1) RU2174115C2 (no)
UA (1) UA62915C2 (no)
WO (1) WO1996040628A1 (no)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5741818A (en) 1995-06-07 1998-04-21 University Of Saskatchewan Semicarbazones having CNS activity and pharmaceutical preparations containing same
AU738197C (en) 1997-04-22 2002-05-16 Cocensys, Inc. Carbocyclic and heterocyclic substituted semicarbazones and thiosemicarbazones and the use thereof
EP1568690A1 (en) * 1997-04-22 2005-08-31 Euro-Celtique S.A. The use of carbocyclic and heterocyclic substituted semicarbazones and thiosemicarbazones as sodium channel blockers
US6479484B1 (en) 1997-11-21 2002-11-12 Euro-Celtique S.A. Substituted 2-aminoacetamides and the use thereof
GB9727523D0 (en) 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
IL137671A0 (en) * 1998-02-04 2001-10-31 Euro Celtique Sa Semicarbazide derivatives and pharmaceutical compositions containing the same
US6281211B1 (en) 1999-02-04 2001-08-28 Euro-Celtique S.A. Substituted semicarbazides and the use thereof
HUP0201314A3 (en) 1999-03-26 2003-02-28 Euro Celtique Sa Aryl substituted pyrazoles, imidazoles, oxazoles, thiazoles and pyrroles, and the use thereof and pharmaceutical compositions containing them
DE60022333T2 (de) * 1999-04-09 2006-07-06 Euro-Celtique S.A. Natrium kanalblocker zusammensetzungen und deren verwendung
US8771740B2 (en) 1999-12-20 2014-07-08 Nicholas J. Kerkhof Process for producing nanoparticles by spray drying
DE60020732T2 (de) 1999-12-20 2006-05-11 Kerkhof, Nicholas J., Rio Vista Verfahren zur herstellung von nanometer partikeln durch fliessbett- sprühtrocknung
AR029489A1 (es) 2000-03-10 2003-07-02 Euro Celtique Sa Piridinas, pirimidinas, pirazinas, triazinas sustituidas por arilo, composiciones farmaceuticas y el uso de las mismas para la manufactura de un medicamento
WO2001072714A2 (en) * 2000-03-24 2001-10-04 Euro-Celtique S.A. Aryl substituted pyrazoles, triazoles and tetrazoles as sodium channel blocker
GB0025208D0 (en) 2000-10-13 2000-11-29 Euro Celtique Sa Delayed release pharmaceutical formulations
WO2002089745A2 (en) * 2001-05-10 2002-11-14 Cytovia, Inc. Substituted n'-(arylcarbonyl)-benzhydrazides, n'-(arylcarbonyl)-benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof
WO2002098420A1 (en) * 2001-06-01 2002-12-12 Cytovia, Inc. 4-substituted-1-(arylmethylidene)thiosemicarbazide, 4-substituted-1-(arylcarbonyl)thiosemicarbazide and analogs as activators of caspases and inducers of apoptosis and the use thereof
WO2003006426A1 (en) * 2001-07-13 2003-01-23 Axxima Pharmaceuticals Ag Aromatic guanylhydrazones as effective compounds against neurodiseases
ATE317280T1 (de) * 2001-09-03 2006-02-15 Newron Pharm Spa Pharmazeutische zusammensetzung mit gabapentin oder deren analog und einem alpha-aminoamid und analgetische verwendung dieser zusammensetzung
AR036873A1 (es) 2001-09-07 2004-10-13 Euro Celtique Sa Piridinas aril sustituidas a, composiciones farmaceuticas y el uso de las mismas para la preparacion de un medicamento
AR037233A1 (es) 2001-09-07 2004-11-03 Euro Celtique Sa Piridinas aril sustituidas, composiciones farmaceuticas y el uso de dichos compuestos para la elaboracion de un medicamento
EP1513515A2 (en) * 2002-05-16 2005-03-16 Cytovia, Inc. Substituted 4h-chromenes, 2h-chromenes, chromans and analogs as activators of caspases and inducers of apoptosis and the use thereof
EP1509515A4 (en) * 2002-05-16 2006-07-05 Cytovia Inc SUBSTITUTED 4-ARYL-4H-PYRROLO 2,3-H | CHROMENES AND ANALOGUES AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THEIR USE
EP1438956A1 (en) * 2003-01-16 2004-07-21 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful as antimigraine agents
CN101018546B (zh) * 2004-09-10 2013-06-12 纽朗制药有限公司 作为钠和/或钙通道选择性调节剂的(卤代苄氧基)苄氨基-丙酰胺类
CN103450077B (zh) 2007-06-08 2016-07-06 满康德股份有限公司 IRE-1α抑制剂
JP2012511411A (ja) * 2008-12-10 2012-05-24 ボストン サイエンティフィック サイムド，インコーポレイテッド チタン合金部材とスチール合金部材との間に継手を形成する方法および前記継手を含んでなる医療用デバイス
CN104402771B (zh) * 2014-11-26 2016-09-28 玉林师范学院 对羟基苯甲醛缩氨基脲的合成及在防治植物病害中的应用
CN104974053B (zh) * 2015-06-24 2017-04-26 天津久日新材料股份有限公司 一种新的氨基酮类光引发剂及在uv‑led光固化体系的应用

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE667022A (no)
US3255241A (en) 1961-01-19 1966-06-07 Merck & Co Inc (2-alkylidene acyl)phenoxy-and (2-alkylidene acyl)phenylmercaptocarboxylic acids
NL129087C (no) 1961-01-19
BE622079A (no) 1961-09-11
US3251064A (en) 1962-11-13 1966-05-10 Everett M Schultz beta-aminoacylphenoxy-and beta-aminoacylphenylmercapto-derivatives of monocarboxylicacids
NL300456A (no) 1962-11-13
BE643709A (no) * 1963-02-12 1900-01-01
DE1288086B (no) * 1963-12-26 1969-01-30
US3392171A (en) * 1964-03-20 1968-07-09 Upjohn Co 4-morpholino-4'-hydroxy bicyclohexyls
US3304323A (en) * 1964-03-20 1967-02-14 Upjohn Co Oxygenated dicycloalkyl sulfones
US3303214A (en) * 1964-05-13 1967-02-07 Wallace & Tiernan Inc Nitrososemicarbazides
GB1164608A (en) * 1966-08-23 1969-09-17 May & Baker Ltd Semicarbazone and Thiosemicarbazone Quaternary Salts
US3712914A (en) * 1970-05-14 1973-01-23 Stauffer Chemical Co Arylidene semicarbizides
DE2420618C2 (de) * 1974-04-27 1982-09-16 C.H. Boehringer Sohn, 6507 Ingelheim Aminoalkylanilide, Verfahren zu ihrer Herstellung sowie pharmazeutische Zubereitungen, die diese Aminoalkylanilide enthalten
US4394514A (en) * 1981-04-30 1983-07-19 Smithkline Beckman Corporation Processes for preparing 4-substituted indoles
US5266585A (en) 1981-05-12 1993-11-30 Ciba-Geigy Corporation Arylphenyl ether derivatives, compositions containing these compounds and use thereof
FI77458C (fi) * 1981-05-12 1989-03-10 Ciba Geigy Ag Nya mikrobicida arylfenyleterderivat, foerfarande foer deras framstaellning och deras anvaendning.
US4454337A (en) * 1981-06-29 1984-06-12 Smithkline Beckman Corporation Semicarbazide intermediates for preparing 4-substituted indoles
US5665673A (en) 1988-12-29 1997-09-09 Anderson; Richard J. Potentiating herbicidal compositions
IL94466A (en) 1989-05-25 1995-01-24 Erba Carlo Spa Pharmaceutical preparations containing the history of A-amino carboxamide N-phenylalkyl are converted into such new compounds and their preparation
WO1994006758A1 (en) * 1992-09-21 1994-03-31 University Of Saskatchewan Aryl semicarbazone anticonvulsants
AU2641295A (en) 1994-05-17 1995-12-05 Dowelanco N-(5-isothiazolyl)amide pesticides
US5741818A (en) 1995-06-07 1998-04-21 University Of Saskatchewan Semicarbazones having CNS activity and pharmaceutical preparations containing same
SK56798A3 (en) 1995-10-30 1998-12-02 Smithkline Beecham Corp Protease inhibitors, pharmaceutical composition containing them and their use

Also Published As

Publication number Publication date
PL323666A1 (en) 1998-04-14
ATE206110T1 (de) 2001-10-15
RU2174115C2 (ru) 2001-09-27
HUP9802637A2 (hu) 1999-02-01
HUP9802637A3 (en) 2000-09-28
IL122350A0 (en) 1998-04-05
USRE38425E1 (en) 2004-02-10
AU5993896A (en) 1996-12-30
DE69615558D1 (de) 2001-10-31
DK0836591T3 (da) 2001-11-26
FI974447A0 (fi) 1997-12-05
NZ309707A (en) 1998-11-25
GEP20012414B (en) 2001-04-25
DE69615558T2 (de) 2002-07-11
ES2164889T3 (es) 2002-03-01
CN1062263C (zh) 2001-02-21
NO975663D0 (no) 1997-12-05
CZ387497A3 (cs) 1998-07-15
CN1190388A (zh) 1998-08-12
EP0836591A1 (en) 1998-04-22
PT836591E (pt) 2002-03-28
EP0836591B1 (en) 2001-09-26
BR9609408A (pt) 1999-07-27
US5741818A (en) 1998-04-21
JPH11506109A (ja) 1999-06-02
KR19990022408A (ko) 1999-03-25
WO1996040628A1 (en) 1996-12-19
UA62915C2 (en) 2004-01-15
AU715897B2 (en) 2000-02-10
FI974447A (fi) 1997-12-05
PL184048B1 (pl) 2002-08-30
NO310655B1 (no) 2001-08-06
CA2223935A1 (en) 1996-12-19

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Legal Events

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