DE69615682D1 - N-(1-alkyl-5-phenyl-2,3,4,5-tetrahydro-1-h-benzo[b][1,5]-diazepin-3-yl)-acetamide - Google Patents

N-(1-alkyl-5-phenyl-2,3,4,5-tetrahydro-1-h-benzo[b][1,5]-diazepin-3-yl)-acetamide

Info

Publication number
DE69615682D1
DE69615682D1 DE69615682T DE69615682T DE69615682D1 DE 69615682 D1 DE69615682 D1 DE 69615682D1 DE 69615682 T DE69615682 T DE 69615682T DE 69615682 T DE69615682 T DE 69615682T DE 69615682 D1 DE69615682 D1 DE 69615682D1
Authority
DE
Germany
Prior art keywords
diazepin
acetamide
benzo
tetrahydro
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69615682T
Other languages
English (en)
Other versions
DE69615682T2 (de
Inventor
David A Claremon
Nigel Liverton
Harold G Selnick
Garry R Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of DE69615682D1 publication Critical patent/DE69615682D1/de
Publication of DE69615682T2 publication Critical patent/DE69615682T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/12—1,5-Benzodiazepines; Hydrogenated 1,5-benzodiazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
DE69615682T 1995-06-07 1996-06-03 N-(1-alkyl-5-phenyl-2,3,4,5-tetrahydro-1-h-benzo[b][1,5]-diazepin-3-yl)-acetamide Expired - Fee Related DE69615682T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47653495A 1995-06-07 1995-06-07
PCT/US1996/008331 WO1996040653A1 (en) 1995-06-07 1996-06-03 Novel n-(1-alkyl-5-phenyl-2,3,4,5-tetrahydro-1h-benzo[b][1,4]diazepin-3-yl)-acetamides

Publications (2)

Publication Number Publication Date
DE69615682D1 true DE69615682D1 (de) 2001-11-08
DE69615682T2 DE69615682T2 (de) 2002-07-11

Family

ID=23892257

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69615682T Expired - Fee Related DE69615682T2 (de) 1995-06-07 1996-06-03 N-(1-alkyl-5-phenyl-2,3,4,5-tetrahydro-1-h-benzo[b][1,5]-diazepin-3-yl)-acetamide

Country Status (12)

Country Link
US (1) US5726171A (de)
EP (1) EP0830350B1 (de)
JP (1) JPH11506745A (de)
AT (1) ATE206409T1 (de)
AU (1) AU704592B2 (de)
CA (1) CA2222330A1 (de)
DE (1) DE69615682T2 (de)
DK (1) DK0830350T3 (de)
ES (1) ES2163638T3 (de)
GR (1) GR3036813T3 (de)
PT (1) PT830350E (de)
WO (1) WO1996040653A1 (de)

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US6333321B1 (en) 1997-08-11 2001-12-25 Cor Therapeutics, Inc. Selective factor Xa inhibitors
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US6218382B1 (en) 1997-08-11 2001-04-17 Cor Therapeutics, Inc Selective factor Xa inhibitors
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US6569851B1 (en) 1998-06-22 2003-05-27 Elan Pharmaceutials, Inc. Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
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US6774125B2 (en) 1998-06-22 2004-08-10 Elan Pharmaceuticals, Inc. Deoxyamino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
US6552013B1 (en) 1998-06-22 2003-04-22 Elan Pharmaceuticals, Inc. Deoxyamino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
US6509331B1 (en) 1998-06-22 2003-01-21 Elan Pharmaceuticals, Inc. Deoxyamino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
CA2404273A1 (en) * 2000-04-11 2001-10-18 Bristol-Myers Squibb Pharma Company Substituted lactams as inhibitors of a.beta. protein production
US20100009966A1 (en) * 2001-04-11 2010-01-14 Bristol-Myers Squibb Pharma Company Substituted lactams as inhibitors of abeta protein production
WO2003009815A2 (en) 2001-07-25 2003-02-06 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
EP3827747A1 (de) 2005-04-28 2021-06-02 Otsuka Pharmaceutical Co., Ltd. Pharmainformatiksystem
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(ｒａｐ)-접합체 투여에 의한 간 질환의 치료
EP3395372B1 (de) 2009-02-20 2022-04-06 EnhanX Biopharm Inc. Freisetzungssystem für glutathionbasiertes arzneimittel
IL255113B (en) 2009-05-06 2022-09-01 Laboratory Skin Care Inc Preparations for administration through the skin that include complexes of an active substance with calcium phosphate and methods of using them
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
KR20180114910A (ko) 2016-02-05 2018-10-19 데날리 테라퓨틱스 인크. 수용체-상호작용 단백질 키나제 1의 억제제
LT3552017T (lt) 2016-12-09 2022-05-10 Denali Therapeutics Inc. Junginiai, naudotini kaip ripk1 inhibitoriai

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Also Published As

Publication number Publication date
EP0830350B1 (de) 2001-10-04
AU5886496A (en) 1996-12-30
DK0830350T3 (da) 2001-11-19
PT830350E (pt) 2002-02-28
JPH11506745A (ja) 1999-06-15
DE69615682T2 (de) 2002-07-11
US5726171A (en) 1998-03-10
ES2163638T3 (es) 2002-02-01
AU704592B2 (en) 1999-04-29
CA2222330A1 (en) 1996-12-19
ATE206409T1 (de) 2001-10-15
EP0830350A4 (de) 1998-09-30
EP0830350A1 (de) 1998-03-25
GR3036813T3 (en) 2002-01-31
WO1996040653A1 (en) 1996-12-19

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee