NO971306D0 - Imidazolderivater - Google Patents
ImidazolderivaterInfo
- Publication number
- NO971306D0 NO971306D0 NO971306A NO971306A NO971306D0 NO 971306 D0 NO971306 D0 NO 971306D0 NO 971306 A NO971306 A NO 971306A NO 971306 A NO971306 A NO 971306A NO 971306 D0 NO971306 D0 NO 971306D0
- Authority
- NO
- Norway
- Prior art keywords
- alkyl
- halogeno
- formula
- imidazole
- hydrogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C07D233/58—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Dental Preparations (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP25749094 | 1994-09-26 | ||
JP8469095 | 1995-03-15 | ||
JP22720595 | 1995-08-12 | ||
PCT/JP1995/001936 WO1996010019A1 (fr) | 1994-09-26 | 1995-09-25 | Derive imidazole |
Publications (3)
Publication Number | Publication Date |
---|---|
NO971306D0 true NO971306D0 (no) | 1997-03-20 |
NO971306L NO971306L (no) | 1997-05-21 |
NO308739B1 NO308739B1 (no) | 2000-10-23 |
Family
ID=27304632
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO971306A NO308739B1 (no) | 1994-09-26 | 1997-03-20 | Imidazolderivater samt medisinsk sammensetning og anti-HIV- sammensetning omfattende samme |
Country Status (20)
Country | Link |
---|---|
US (2) | US5910506A (no) |
EP (1) | EP0786455B1 (no) |
JP (1) | JP3155009B2 (no) |
KR (1) | KR100387157B1 (no) |
CN (1) | CN1093535C (no) |
AT (1) | ATE255564T1 (no) |
BR (1) | BR9509024A (no) |
CA (1) | CA2200316C (no) |
DE (1) | DE69532245T2 (no) |
DK (1) | DK0786455T3 (no) |
ES (1) | ES2211917T3 (no) |
FI (1) | FI971234A (no) |
HU (1) | HUT77357A (no) |
MX (1) | MX9702030A (no) |
NO (1) | NO308739B1 (no) |
PL (1) | PL183931B1 (no) |
PT (1) | PT786455E (no) |
RU (1) | RU2157368C2 (no) |
TW (1) | TW401404B (no) |
WO (1) | WO1996010019A1 (no) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU1940897A (en) * | 1996-03-28 | 1997-10-17 | Shionogi & Co., Ltd. | Lymph-absorbable imidazole derivatives |
WO1997037657A1 (fr) * | 1996-04-04 | 1997-10-16 | Shionogi & Co., Ltd. | Composition anti-vih contenant un derive d'imidazole |
BR9714436A (pt) * | 1996-12-26 | 2000-03-21 | Shionogi & Co | Processo para produção de derivados de imidazol |
US6018049A (en) * | 1996-12-26 | 2000-01-25 | Shionogi & Co., Ltd. | Process for the preparation of carbamoylated imidazole derivatives |
TWI232214B (en) | 1998-04-16 | 2005-05-11 | Shionogi & Co | Preparation of aryl sulfenyl halide |
DE60013583T8 (de) | 1999-04-12 | 2006-06-08 | Shionogi & Co., Ltd. | Verfahren zur herstellung von arzneimitteln eines basischen hydrophoben wirkstoffs |
GB0016787D0 (en) | 2000-07-07 | 2000-08-30 | Pfizer Ltd | Compounds useful in therapy |
YU52303A (sh) | 2001-01-31 | 2006-05-25 | Warner-Lambert Company | Postupak karbamoilacije alkohola |
PT1370539E (pt) * | 2001-02-23 | 2012-02-14 | Leuven K U Res & Dev | Derivados de n-aminoimidazole inibidores de hiv |
PL217629B1 (pl) | 2001-04-10 | 2014-08-29 | Pfizer | Pochodne pirazolu i kompozycje farmaceutyczne zawierające je oraz ich zastosowanie |
GB0113524D0 (en) * | 2001-06-04 | 2001-07-25 | Hoffmann La Roche | Pyrazole derivatives |
PL211979B1 (pl) * | 2002-04-26 | 2012-07-31 | Gilead Sciences | Pochodne fosfonianowe, ich zastosowanie w leczeniu zakażenia wirusem HIV i chorób wpływających na białe krwinki, oraz kompozycje farmaceutyczne zawierające te związki |
TW200423930A (en) | 2003-02-18 | 2004-11-16 | Hoffmann La Roche | Non-nucleoside reverse transcriptase inhibitors |
MXPA05010081A (es) | 2003-03-24 | 2005-11-23 | Hoffmann La Roche | Bencil-piridazinonas como inhibidores de transcriptasa inversa. |
US7470724B2 (en) | 2003-04-25 | 2008-12-30 | Gilead Sciences, Inc. | Phosphonate compounds having immuno-modulatory activity |
US7432261B2 (en) | 2003-04-25 | 2008-10-07 | Gilead Sciences, Inc. | Anti-inflammatory phosphonate compounds |
MXPA05011296A (es) | 2003-04-25 | 2006-01-24 | Gilead Sciences Inc | Conjugados de fosfonato inhibidores de la cinasa. |
US7452901B2 (en) | 2003-04-25 | 2008-11-18 | Gilead Sciences, Inc. | Anti-cancer phosphonate analogs |
WO2004096286A2 (en) | 2003-04-25 | 2004-11-11 | Gilead Sciences, Inc. | Antiviral phosphonate analogs |
US7427636B2 (en) | 2003-04-25 | 2008-09-23 | Gilead Sciences, Inc. | Inosine monophosphate dehydrogenase inhibitory phosphonate compounds |
WO2005002626A2 (en) | 2003-04-25 | 2005-01-13 | Gilead Sciences, Inc. | Therapeutic phosphonate compounds |
US7300924B2 (en) | 2003-04-25 | 2007-11-27 | Gilead Sciences, Inc. | Anti-infective phosphonate analogs |
US7407965B2 (en) | 2003-04-25 | 2008-08-05 | Gilead Sciences, Inc. | Phosphonate analogs for treating metabolic diseases |
WO2005016912A1 (en) * | 2003-08-19 | 2005-02-24 | Pfizer Inc. | An efficient microbial preparation of capravirine metabolites m4 and m5 |
US7432273B2 (en) | 2003-10-24 | 2008-10-07 | Gilead Sciences, Inc. | Phosphonate analogs of antimetabolites |
EP1678321A1 (en) | 2003-10-24 | 2006-07-12 | Gilead Sciences, Inc. | Methods and compositions for identifying therapeutic compounds |
US7427624B2 (en) | 2003-10-24 | 2008-09-23 | Gilead Sciences, Inc. | Purine nucleoside phosphorylase inhibitory phosphonate compounds |
US7432272B2 (en) | 2003-12-22 | 2008-10-07 | Gilead Sciences, Inc. | Antiviral analogs |
MXPA06011884A (es) * | 2004-04-14 | 2006-12-14 | Pfizer | Compuestos de imidazol unidos a azufre para el tratamiento del virus de inmunodeficiencia humana. |
WO2006110157A2 (en) | 2004-07-27 | 2006-10-19 | Gilead Sciences, Inc. | Nucleoside phosphonate conjugates as anti hiv agents |
EP1798226A4 (en) | 2004-08-04 | 2009-06-17 | Taisho Pharmaceutical Co Ltd | TRAIZOL DERIVATIVE |
CA2592909A1 (en) * | 2005-01-06 | 2006-07-13 | Pfizer Limited | Imidazole derivatives as enzyme reverse transcriptase modulators |
EP2130822A1 (en) * | 2005-12-01 | 2009-12-09 | F. Hoffmann-La Roche AG | 2,4,5-triphenyl imidazoline derivatives as inhibitors of the interaction between p53 and mdm2 proteins for use as anticancer agents |
CN101415691B (zh) | 2006-02-03 | 2011-12-14 | 大正制药株式会社 | 三唑衍生物 |
EP1988081B1 (en) * | 2006-02-06 | 2012-10-17 | Taisho Pharmaceutical Co., Ltd | Binding inhibitor of sphingosine-1-phosphate |
US7649098B2 (en) * | 2006-02-24 | 2010-01-19 | Lexicon Pharmaceuticals, Inc. | Imidazole-based compounds, compositions comprising them and methods of their use |
US7994205B2 (en) * | 2006-03-31 | 2011-08-09 | Takeda Pharmaceutical Company Limited | Aryl-or heteroaryl-sulfonyl compounds as acid secretion inhibitors |
WO2008019968A1 (en) | 2006-08-16 | 2008-02-21 | F. Hoffmann-La Roche Ag | Non-nucleoside reverse transcriptase inhibitors |
PT2177512E (pt) | 2007-08-01 | 2012-05-07 | Taisho Pharmaceutical Co Ltd | Inibidor da ligação de s1p1 |
TW200920355A (en) * | 2007-09-06 | 2009-05-16 | Lexicon Pharmaceuticals Inc | Compositions and methods for treating immunological and inflammatory diseases and disorders |
JP5345140B2 (ja) * | 2007-09-28 | 2013-11-20 | 武田薬品工業株式会社 | プロトンポンプ阻害剤としての5員複素環化合物 |
JP5411160B2 (ja) | 2007-12-21 | 2014-02-12 | エフ.ホフマン−ラ ロシュ アーゲー | 複素環式抗ウイルス性化合物 |
PL2307435T3 (pl) | 2008-07-08 | 2012-11-30 | Gilead Sciences Inc | Sole związków inhibitorów HIV |
EP2396304A1 (en) * | 2009-02-12 | 2011-12-21 | Exelixis, Inc. | Triazole and imidazole derivatives for use as tgr5 agonists in the treatment of diabetes and obesity |
MA33214B1 (fr) | 2009-03-26 | 2012-04-02 | Takeda Pharmaceutical | Compose pyrazole |
EP2508511A1 (en) * | 2011-04-07 | 2012-10-10 | Laboratoire Biodim | Inhibitors of viral replication, their process of preparation and their therapeutical uses |
SI2890684T1 (en) * | 2012-07-24 | 2018-06-29 | Bial-Portela & Ca, S.A. | THE CLOTHING MACHINE AND THEIR USE AS ENCLOSURE INHIBITORS |
EP2716632A1 (en) | 2012-10-05 | 2014-04-09 | Laboratoire Biodim | Inhibitors of viral replication, their process of preparation and their therapeutical uses |
EP2716639A1 (en) | 2012-10-05 | 2014-04-09 | Laboratoire Biodim | Inhibitors of viral replication, their process of preparation and their therapeutical uses |
GB201602934D0 (en) | 2016-02-19 | 2016-04-06 | Cancer Res Inst Royal | Compounds |
EP3381905A1 (en) * | 2017-03-30 | 2018-10-03 | Institut National de la Sante et de la Recherche Medicale (INSERM) | Novel antiviral compounds |
PL3661937T3 (pl) | 2017-08-01 | 2021-12-20 | Gilead Sciences, Inc. | Formy krystaliczne ((s)-((((2r,5r)-5-(6-amino-9h-puryn-9-ylo)-4-fluoro-2,5-dihydrofuran-2-ylo)oksy)metylo)(fenoksy)fosforylo)-l-alaninianu etylu (gs-9131) do leczenia zakażeń wirusowych |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63150266A (ja) * | 1986-12-12 | 1988-06-22 | Mitsui Petrochem Ind Ltd | ベンジルイミダゾ−ル誘導体 |
JPH0283373A (ja) * | 1988-05-19 | 1990-03-23 | Nippon Soda Co Ltd | 5員環の複素環化合物及びその製造方法 |
IL98319A (en) * | 1990-07-05 | 1997-04-15 | Roussel Uclaf | Sulphurous derivatives of imidazole, their preparation process, and pharmaceutical compositions containing them |
TW235963B (no) * | 1992-01-16 | 1994-12-11 | Shionogi & Co | |
DE10230797C2 (de) * | 2001-07-16 | 2003-09-25 | Dieter Reif | Befestigungsklammer zur Verbindung von Holzbauteilen |
-
1995
- 1995-09-25 RU RU97106829/04A patent/RU2157368C2/ru not_active IP Right Cessation
- 1995-09-25 WO PCT/JP1995/001936 patent/WO1996010019A1/ja active IP Right Grant
- 1995-09-25 US US08/809,624 patent/US5910506A/en not_active Expired - Fee Related
- 1995-09-25 DK DK95932231T patent/DK0786455T3/da active
- 1995-09-25 EP EP95932231A patent/EP0786455B1/en not_active Expired - Lifetime
- 1995-09-25 AT AT95932231T patent/ATE255564T1/de not_active IP Right Cessation
- 1995-09-25 CA CA002200316A patent/CA2200316C/en not_active Expired - Fee Related
- 1995-09-25 JP JP51159896A patent/JP3155009B2/ja not_active Expired - Fee Related
- 1995-09-25 ES ES95932231T patent/ES2211917T3/es not_active Expired - Lifetime
- 1995-09-25 KR KR1019970701989A patent/KR100387157B1/ko not_active IP Right Cessation
- 1995-09-25 CN CN95195260A patent/CN1093535C/zh not_active Expired - Fee Related
- 1995-09-25 PT PT95932231T patent/PT786455E/pt unknown
- 1995-09-25 DE DE69532245T patent/DE69532245T2/de not_active Expired - Fee Related
- 1995-09-25 HU HU9701899A patent/HUT77357A/hu not_active Application Discontinuation
- 1995-09-25 MX MX9702030A patent/MX9702030A/es not_active IP Right Cessation
- 1995-09-25 BR BR9509024A patent/BR9509024A/pt not_active IP Right Cessation
- 1995-09-25 PL PL95320009A patent/PL183931B1/pl not_active IP Right Cessation
- 1995-09-29 TW TW084110183A patent/TW401404B/zh not_active IP Right Cessation
-
1997
- 1997-03-20 NO NO971306A patent/NO308739B1/no unknown
- 1997-03-25 FI FI971234A patent/FI971234A/fi unknown
-
1998
- 1998-12-04 US US09/205,289 patent/US6147097A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
KR970706260A (ko) | 1997-11-03 |
US6147097A (en) | 2000-11-14 |
NO971306L (no) | 1997-05-21 |
JP3155009B2 (ja) | 2001-04-09 |
EP0786455A1 (en) | 1997-07-30 |
DE69532245D1 (en) | 2004-01-15 |
PL320009A1 (en) | 1997-09-01 |
NO308739B1 (no) | 2000-10-23 |
CN1093535C (zh) | 2002-10-30 |
KR100387157B1 (ko) | 2003-09-29 |
US5910506A (en) | 1999-06-08 |
WO1996010019A1 (fr) | 1996-04-04 |
DE69532245T2 (de) | 2004-09-16 |
CA2200316A1 (en) | 1996-04-04 |
FI971234A (fi) | 1997-05-23 |
ATE255564T1 (de) | 2003-12-15 |
MX9702030A (es) | 1997-06-28 |
BR9509024A (pt) | 1997-09-30 |
TW401404B (en) | 2000-08-11 |
HUT77357A (hu) | 1998-03-30 |
AU706095B2 (en) | 1999-06-10 |
PL183931B1 (pl) | 2002-08-30 |
FI971234A0 (fi) | 1997-03-25 |
AU4788896A (en) | 1996-04-19 |
EP0786455A4 (en) | 1998-12-30 |
CA2200316C (en) | 2004-09-21 |
EP0786455B1 (en) | 2003-12-03 |
CN1158609A (zh) | 1997-09-03 |
ES2211917T3 (es) | 2004-07-16 |
PT786455E (pt) | 2004-02-27 |
RU2157368C2 (ru) | 2000-10-10 |
DK0786455T3 (da) | 2004-03-29 |
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