BR9509024A - Derivados de imidazol - Google Patents
Derivados de imidazolInfo
- Publication number
- BR9509024A BR9509024A BR9509024A BR9509024A BR9509024A BR 9509024 A BR9509024 A BR 9509024A BR 9509024 A BR9509024 A BR 9509024A BR 9509024 A BR9509024 A BR 9509024A BR 9509024 A BR9509024 A BR 9509024A
- Authority
- BR
- Brazil
- Prior art keywords
- alkyl
- halogeno
- imidazole derivatives
- formula
- hydrogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C07D233/58—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Dental Preparations (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP25749094 | 1994-09-26 | ||
JP8469095 | 1995-03-15 | ||
JP22720595 | 1995-08-12 | ||
PCT/JP1995/001936 WO1996010019A1 (fr) | 1994-09-26 | 1995-09-25 | Derive imidazole |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9509024A true BR9509024A (pt) | 1997-09-30 |
Family
ID=27304632
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9509024A BR9509024A (pt) | 1994-09-26 | 1995-09-25 | Derivados de imidazol |
Country Status (20)
Country | Link |
---|---|
US (2) | US5910506A (pt) |
EP (1) | EP0786455B1 (pt) |
JP (1) | JP3155009B2 (pt) |
KR (1) | KR100387157B1 (pt) |
CN (1) | CN1093535C (pt) |
AT (1) | ATE255564T1 (pt) |
BR (1) | BR9509024A (pt) |
CA (1) | CA2200316C (pt) |
DE (1) | DE69532245T2 (pt) |
DK (1) | DK0786455T3 (pt) |
ES (1) | ES2211917T3 (pt) |
FI (1) | FI971234A (pt) |
HU (1) | HUT77357A (pt) |
MX (1) | MX9702030A (pt) |
NO (1) | NO308739B1 (pt) |
PL (1) | PL183931B1 (pt) |
PT (1) | PT786455E (pt) |
RU (1) | RU2157368C2 (pt) |
TW (1) | TW401404B (pt) |
WO (1) | WO1996010019A1 (pt) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE286884T1 (de) * | 1996-03-28 | 2005-01-15 | Shionogi & Co | Durch lymphe absorbierbare imidazolderivate |
EP0906756A4 (en) * | 1996-04-04 | 2000-11-22 | Shionogi & Co | ANTI-HIV COMPOSITION CONTAINING IMIDAZOLE DERIVATIVE |
EP0949249B1 (en) * | 1996-12-26 | 2005-07-13 | Shionogi & Co., Ltd. | Process for producing imidazole derivatives |
AU7890398A (en) * | 1996-12-26 | 1998-07-31 | Shionogi & Co., Ltd. | Process for the preparation of carbamoyllated imidazole derivatives |
TWI232214B (en) | 1998-04-16 | 2005-05-11 | Shionogi & Co | Preparation of aryl sulfenyl halide |
EP1172097B1 (en) | 1999-04-12 | 2004-09-08 | Shionogi & Co., Ltd. | Process for producing medicinal composition of a basic hydrophobic medicinal compound |
GB0016787D0 (en) * | 2000-07-07 | 2000-08-30 | Pfizer Ltd | Compounds useful in therapy |
BR0206806A (pt) | 2001-01-31 | 2004-02-03 | Warner Lambert Co | Método para carbamoilação de álcoois |
HUP0303238A3 (en) * | 2001-02-23 | 2004-05-28 | Leuven K U Res & Dev | Hiv inhibiting n-aminoimidazole derivatives, their use, process for their preparation and pharmaceutical compositions containing them |
NZ529403A (en) | 2001-04-10 | 2005-06-24 | Pfizer | Pyrazole derivatives for treating HIV |
GB0113524D0 (en) | 2001-06-04 | 2001-07-25 | Hoffmann La Roche | Pyrazole derivatives |
BR0309557A (pt) | 2002-04-26 | 2005-03-01 | Gilead Sciences Inc | Inibidores da transcriptase reversa não nucleosìdeos |
TW200423930A (en) | 2003-02-18 | 2004-11-16 | Hoffmann La Roche | Non-nucleoside reverse transcriptase inhibitors |
EP1608629A1 (en) | 2003-03-24 | 2005-12-28 | F. Hoffmann-La Roche Ag | Benzyl-pyridazinons as reverse transcriptase inhibitors |
AU2004233897A1 (en) | 2003-04-25 | 2004-11-11 | Gilead Sciences, Inc. | Kinase inhibitor phosphonate conjugates |
US7432261B2 (en) | 2003-04-25 | 2008-10-07 | Gilead Sciences, Inc. | Anti-inflammatory phosphonate compounds |
US7427636B2 (en) | 2003-04-25 | 2008-09-23 | Gilead Sciences, Inc. | Inosine monophosphate dehydrogenase inhibitory phosphonate compounds |
EA014685B1 (ru) | 2003-04-25 | 2010-12-30 | Джилид Сайэнс, Инк. | Фосфонатсодержащие антивирусные соединения (варианты) и фармацевтическая композиция на их основе |
US7452901B2 (en) | 2003-04-25 | 2008-11-18 | Gilead Sciences, Inc. | Anti-cancer phosphonate analogs |
US7407965B2 (en) | 2003-04-25 | 2008-08-05 | Gilead Sciences, Inc. | Phosphonate analogs for treating metabolic diseases |
US7470724B2 (en) | 2003-04-25 | 2008-12-30 | Gilead Sciences, Inc. | Phosphonate compounds having immuno-modulatory activity |
WO2005002626A2 (en) | 2003-04-25 | 2005-01-13 | Gilead Sciences, Inc. | Therapeutic phosphonate compounds |
WO2004096285A2 (en) | 2003-04-25 | 2004-11-11 | Gilead Sciences, Inc. | Anti-infective phosphonate conjugates |
WO2005016912A1 (en) * | 2003-08-19 | 2005-02-24 | Pfizer Inc. | An efficient microbial preparation of capravirine metabolites m4 and m5 |
EP1678321A1 (en) | 2003-10-24 | 2006-07-12 | Gilead Sciences, Inc. | Methods and compositions for identifying therapeutic compounds |
US7427624B2 (en) | 2003-10-24 | 2008-09-23 | Gilead Sciences, Inc. | Purine nucleoside phosphorylase inhibitory phosphonate compounds |
US7432273B2 (en) | 2003-10-24 | 2008-10-07 | Gilead Sciences, Inc. | Phosphonate analogs of antimetabolites |
NZ547907A (en) | 2003-12-22 | 2010-07-30 | Gilead Sciences Inc | 4'-Substituted carbovir-and abacavir-derivatives as well as related compounds with HIV and HCV antiviral activity |
EP1740550A1 (en) * | 2004-04-14 | 2007-01-10 | Pfizer Limited | Sulphur-linked imidazole compounds for the treament of hiv |
UA88313C2 (ru) | 2004-07-27 | 2009-10-12 | Гилиад Сайенсиз, Инк. | Фосфонатные аналоги соединений ингибиторов вич |
JP4993407B2 (ja) * | 2004-08-04 | 2012-08-08 | 大正製薬株式会社 | トリアゾール誘導体 |
JP2008526828A (ja) * | 2005-01-06 | 2008-07-24 | ファイザー・リミテッド | 逆転写酵素モジュレーターとしてのイミダゾール誘導体 |
BRPI0619236A2 (pt) * | 2005-12-01 | 2011-09-20 | Hoffmann La Roche | derivados de 2,4,5-trifenil imidazolina, composição farmacêutica que os compreende, uso e processo para a sìntese dos mesmos |
CN101415691B (zh) * | 2006-02-03 | 2011-12-14 | 大正制药株式会社 | 三唑衍生物 |
EP1988081B1 (en) * | 2006-02-06 | 2012-10-17 | Taisho Pharmaceutical Co., Ltd | Binding inhibitor of sphingosine-1-phosphate |
US7649098B2 (en) * | 2006-02-24 | 2010-01-19 | Lexicon Pharmaceuticals, Inc. | Imidazole-based compounds, compositions comprising them and methods of their use |
WO2007114338A1 (ja) | 2006-03-31 | 2007-10-11 | Takeda Pharmaceutical Company Limited | 酸分泌抑制薬 |
ES2360893T3 (es) | 2006-08-16 | 2011-06-10 | F. Hoffmann-La Roche Ag | Inhibidores no nucleósidos de la transcriptasa inversa. |
US8048898B2 (en) | 2007-08-01 | 2011-11-01 | Taisho Pharmaceutical Co., Ltd | Inhibitor of binding of S1P1 |
TW200920355A (en) * | 2007-09-06 | 2009-05-16 | Lexicon Pharmaceuticals Inc | Compositions and methods for treating immunological and inflammatory diseases and disorders |
US20090156642A1 (en) * | 2007-09-28 | 2009-06-18 | Takeda Pharmaceutical Company Limited | 5-Membered heterocyclic compound |
AU2008340422B2 (en) | 2007-12-21 | 2014-06-19 | F. Hoffmann-La Roche Ag | Heterocyclic antiviral compounds |
EA018308B1 (ru) | 2008-07-08 | 2013-07-30 | Джилид Сайэнс, Инк. | Соли соединений ингибиторов вич |
JP2012517479A (ja) * | 2009-02-12 | 2012-08-02 | エグゼリクシス, インコーポレイテッド | 糖尿病および肥満の処置においてtgr5アゴニストとして使用するためのトリアゾールおよびイミダゾール誘導体 |
EA019853B1 (ru) | 2009-03-26 | 2014-06-30 | Такеда Фармасьютикал Компани Лимитед | Производные 1-(пиридин-3-ил)-3-метиламинометил-5-фенилсульфонилпиразола |
EP2508511A1 (en) | 2011-04-07 | 2012-10-10 | Laboratoire Biodim | Inhibitors of viral replication, their process of preparation and their therapeutical uses |
AR091888A1 (es) * | 2012-07-24 | 2015-03-11 | Bial Portela & Ca Sa | Compuestos de urea y su uso como inhibidores de enzimas |
EP2716632A1 (en) | 2012-10-05 | 2014-04-09 | Laboratoire Biodim | Inhibitors of viral replication, their process of preparation and their therapeutical uses |
EP2716639A1 (en) | 2012-10-05 | 2014-04-09 | Laboratoire Biodim | Inhibitors of viral replication, their process of preparation and their therapeutical uses |
GB201602934D0 (en) | 2016-02-19 | 2016-04-06 | Cancer Res Inst Royal | Compounds |
EP3381905A1 (en) * | 2017-03-30 | 2018-10-03 | Institut National de la Sante et de la Recherche Medicale (INSERM) | Novel antiviral compounds |
PL3661937T3 (pl) | 2017-08-01 | 2021-12-20 | Gilead Sciences, Inc. | Formy krystaliczne ((s)-((((2r,5r)-5-(6-amino-9h-puryn-9-ylo)-4-fluoro-2,5-dihydrofuran-2-ylo)oksy)metylo)(fenoksy)fosforylo)-l-alaninianu etylu (gs-9131) do leczenia zakażeń wirusowych |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63150266A (ja) * | 1986-12-12 | 1988-06-22 | Mitsui Petrochem Ind Ltd | ベンジルイミダゾ−ル誘導体 |
JPH0283373A (ja) * | 1988-05-19 | 1990-03-23 | Nippon Soda Co Ltd | 5員環の複素環化合物及びその製造方法 |
IL98319A (en) * | 1990-07-05 | 1997-04-15 | Roussel Uclaf | Sulphurous derivatives of imidazole, their preparation process, and pharmaceutical compositions containing them |
TW235963B (pt) * | 1992-01-16 | 1994-12-11 | Shionogi & Co | |
DE10230797C2 (de) * | 2001-07-16 | 2003-09-25 | Dieter Reif | Befestigungsklammer zur Verbindung von Holzbauteilen |
-
1995
- 1995-09-25 CA CA002200316A patent/CA2200316C/en not_active Expired - Fee Related
- 1995-09-25 PT PT95932231T patent/PT786455E/pt unknown
- 1995-09-25 AT AT95932231T patent/ATE255564T1/de not_active IP Right Cessation
- 1995-09-25 HU HU9701899A patent/HUT77357A/hu not_active Application Discontinuation
- 1995-09-25 US US08/809,624 patent/US5910506A/en not_active Expired - Fee Related
- 1995-09-25 EP EP95932231A patent/EP0786455B1/en not_active Expired - Lifetime
- 1995-09-25 RU RU97106829/04A patent/RU2157368C2/ru not_active IP Right Cessation
- 1995-09-25 CN CN95195260A patent/CN1093535C/zh not_active Expired - Fee Related
- 1995-09-25 JP JP51159896A patent/JP3155009B2/ja not_active Expired - Fee Related
- 1995-09-25 KR KR1019970701989A patent/KR100387157B1/ko not_active IP Right Cessation
- 1995-09-25 PL PL95320009A patent/PL183931B1/pl not_active IP Right Cessation
- 1995-09-25 ES ES95932231T patent/ES2211917T3/es not_active Expired - Lifetime
- 1995-09-25 WO PCT/JP1995/001936 patent/WO1996010019A1/ja active IP Right Grant
- 1995-09-25 DK DK95932231T patent/DK0786455T3/da active
- 1995-09-25 BR BR9509024A patent/BR9509024A/pt not_active IP Right Cessation
- 1995-09-25 DE DE69532245T patent/DE69532245T2/de not_active Expired - Fee Related
- 1995-09-25 MX MX9702030A patent/MX9702030A/es not_active IP Right Cessation
- 1995-09-29 TW TW084110183A patent/TW401404B/zh not_active IP Right Cessation
-
1997
- 1997-03-20 NO NO971306A patent/NO308739B1/no unknown
- 1997-03-25 FI FI971234A patent/FI971234A/fi unknown
-
1998
- 1998-12-04 US US09/205,289 patent/US6147097A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP3155009B2 (ja) | 2001-04-09 |
EP0786455A1 (en) | 1997-07-30 |
DK0786455T3 (da) | 2004-03-29 |
FI971234A0 (fi) | 1997-03-25 |
DE69532245T2 (de) | 2004-09-16 |
FI971234A (fi) | 1997-05-23 |
EP0786455B1 (en) | 2003-12-03 |
NO971306L (no) | 1997-05-21 |
HUT77357A (hu) | 1998-03-30 |
TW401404B (en) | 2000-08-11 |
WO1996010019A1 (fr) | 1996-04-04 |
US6147097A (en) | 2000-11-14 |
ATE255564T1 (de) | 2003-12-15 |
CA2200316A1 (en) | 1996-04-04 |
KR970706260A (ko) | 1997-11-03 |
AU4788896A (en) | 1996-04-19 |
AU706095B2 (en) | 1999-06-10 |
ES2211917T3 (es) | 2004-07-16 |
CN1093535C (zh) | 2002-10-30 |
KR100387157B1 (ko) | 2003-09-29 |
CN1158609A (zh) | 1997-09-03 |
RU2157368C2 (ru) | 2000-10-10 |
PL183931B1 (pl) | 2002-08-30 |
CA2200316C (en) | 2004-09-21 |
PT786455E (pt) | 2004-02-27 |
MX9702030A (es) | 1997-06-28 |
EP0786455A4 (en) | 1998-12-30 |
PL320009A1 (en) | 1997-09-01 |
NO971306D0 (no) | 1997-03-20 |
US5910506A (en) | 1999-06-08 |
DE69532245D1 (en) | 2004-01-15 |
NO308739B1 (no) | 2000-10-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR9509024A (pt) | Derivados de imidazol | |
NO179142C (no) | 3-benzyliden-1-karbamoyl-2-pyrrolidon-analoger | |
ES2123858T3 (es) | Derivados de amidas ciclicas. | |
ID29452A (id) | 4-okso-1,4-dihidro-3-quinolinkarboksamida sebagai agen-agen antivirus | |
DK0477778T3 (da) | Benzen-, pyridin- eller pyrimidinderivat | |
KR920701240A (ko) | 글루타티온 유도체 | |
ES2169220T3 (es) | Derivados de vitamina d3 con sustituyentes en la posicion 2. | |
DE60016384D1 (de) | Chondrogonese promotoren und indolin-2-on derivate | |
ATE320417T1 (de) | Naphthimidobenzamid-derivate | |
EP0785190A3 (pt) | ||
FI904728A0 (fi) | Benzanilider. | |
DK0594329T3 (da) | Antimikrobielle midler, der omfatter polykvaternære ammoniumforbindelser | |
ATE318265T1 (de) | Amidin-derivate, ihre herstellung und verwendung als medikamenten | |
TR199800039T1 (xx) | Pirimidin n�kleozit t�revleri. | |
EP1179345A4 (en) | ANTI-INFLAMMATORY AGENTS AND INHIBITORS CONTAINING 1,4-DIHYDROPYRIDINE DERIVATIVES REDUCING THE INCREASE IN OCULAR VOLTAGE CAUSED BY LASER IRRADIATION | |
BR9305092A (pt) | Processo para a preparação de derivados de 5-pirazolmercáptan, composto ditiocarbazato de etilideno, processo para a preparação de derivados do mesmo | |
ES2077697T3 (es) | Derivados de 1-fenoxicarbonil-2-pirrolidinona y agentes nootropicos. | |
TH17157A (th) | อนุพันธ์ไพริมิดีนอะไซโคลนิวคลีโอไซด์ |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EG | Technical examination (opinion): publication of technical examination (opinion) | ||
HJEG | Technical examination (opinion): technical examination (opinion) related to article 229 of industrial property law | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] | ||
B24C | Patent annual fee: request for for restoration |
Free format text: REFERENTE 12A., 13A., E 14A. ANUIDADES. |
|
B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE AO DESPACHO 24.3 NA RPI 2050 DE 20/04/2010, E COMPROVAR O RECOLHIMENTO DA 15A,16A,17A E 18A ANUIDADES. |