NO953352D0 - Ortosubstituerte benzosyrederivater - Google Patents
Ortosubstituerte benzosyrederivaterInfo
- Publication number
- NO953352D0 NO953352D0 NO953352A NO953352A NO953352D0 NO 953352 D0 NO953352 D0 NO 953352D0 NO 953352 A NO953352 A NO 953352A NO 953352 A NO953352 A NO 953352A NO 953352 D0 NO953352 D0 NO 953352D0
- Authority
- NO
- Norway
- Prior art keywords
- benzoic acid
- halogen
- ortho
- acid derivatives
- substituted benzoic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
- C07C317/48—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C317/50—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
- C07C317/48—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/17—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
- C07C317/46—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4430212A DE4430212A1 (de) | 1994-08-28 | 1994-08-28 | Ortho-substituierte Benzoesäure-Derivate |
Publications (3)
Publication Number | Publication Date |
---|---|
NO953352D0 true NO953352D0 (no) | 1995-08-25 |
NO953352L NO953352L (no) | 1996-02-29 |
NO305794B1 NO305794B1 (no) | 1999-07-26 |
Family
ID=6526569
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO953352A NO305794B1 (no) | 1994-08-28 | 1995-08-25 | Ortosubstituerte benzosyrederivater, farmas°ytiske preparater som inneholder minst Ún slik forbindelse, samt anvendelse av forbindelsene til fremstilling av legemidler |
Country Status (23)
Country | Link |
---|---|
US (1) | US5849796A (no) |
EP (1) | EP0704431B1 (no) |
JP (1) | JPH0859602A (no) |
KR (1) | KR100406686B1 (no) |
CN (1) | CN1068587C (no) |
AT (1) | ATE193282T1 (no) |
AU (1) | AU703633B2 (no) |
BR (1) | BR9503817A (no) |
CA (1) | CA2156959A1 (no) |
CZ (1) | CZ289492B6 (no) |
DE (2) | DE4430212A1 (no) |
DK (1) | DK0704431T3 (no) |
ES (1) | ES2147810T3 (no) |
GR (1) | GR3033989T3 (no) |
HU (1) | HUT74946A (no) |
NO (1) | NO305794B1 (no) |
PL (1) | PL181183B1 (no) |
PT (1) | PT704431E (no) |
RU (1) | RU2125981C1 (no) |
SK (1) | SK282202B6 (no) |
TW (1) | TW406067B (no) |
UA (1) | UA44238C2 (no) |
ZA (1) | ZA957161B (no) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19713427A1 (de) * | 1997-04-01 | 1998-10-08 | Hoechst Ag | Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
DE19919349A1 (de) * | 1999-04-28 | 2000-11-02 | Merck Patent Gmbh | Verfahren zur Herstellung eines Benzoylguanidinderivates |
EP1318991B1 (en) * | 2000-09-21 | 2006-08-16 | Novation Pharmaceuticals Inc. | Benzoic acid derivatives and uses thereof |
EP1431267A4 (en) * | 2001-08-09 | 2004-12-22 | Ono Pharmaceutical Co | COMPOUNDS DERIVED FROM CARBOXYLIC ACID AND MEDICAMENTS COMPRISING SUCH COMPOUNDS AS ACTIVE INGREDIENT |
HUE051368T2 (hu) * | 2002-03-20 | 2021-03-01 | Univ Maryland | Nem szelektív kationcsatorna idegsejtekben és a csatornát blokkoló vegyületek az agyduzzanat kezelésére |
US8980952B2 (en) * | 2002-03-20 | 2015-03-17 | University Of Maryland, Baltimore | Methods for treating brain swelling with a compound that blocks a non-selective cation channel |
EP1802313B1 (en) * | 2004-09-18 | 2010-11-03 | University of Maryland, Baltimore | Therapeutic agents trageting the ncca-atp channel and methods of use thereof |
EP1799227B1 (en) | 2004-09-18 | 2010-11-10 | University of Maryland, Baltimore | Therapeutic agents targeting the nc ca-atp channel and methods of use thereof |
MX2007016463A (es) * | 2005-06-22 | 2008-03-04 | Plexxikon Inc | Derivados de pirrolo [2,3-b] piridina como inhibidores de proteina cinasa. |
WO2008089103A2 (en) * | 2007-01-12 | 2008-07-24 | University Of Maryland, Baltimore | Targeting ncca-atp channel for organ protection following ischemic episode |
WO2008098160A1 (en) * | 2007-02-09 | 2008-08-14 | University Of Maryland, Baltimore | Antagonists of a non-selective cation channel in neural cells |
CA2691199C (en) | 2007-06-22 | 2017-09-12 | Marc J. Simard | Inhibitors of ncca-atp channels for therapy |
LT6401B (lt) * | 2015-07-28 | 2017-06-12 | Vilniaus Universitetas | Karboanhidrazės selektyvūs inhibitoriai |
CN105732357A (zh) * | 2016-03-23 | 2016-07-06 | 叶芳 | 2-氯-4氟苯甲酸及其制备方法 |
CN106892852B (zh) * | 2017-03-21 | 2019-07-09 | 重庆医科大学 | 具有抗流感病毒活性的胍基类似物及其制备方法 |
CN111116395B (zh) * | 2019-12-27 | 2023-04-07 | 湖北工业大学 | 多碘代芳香酸类化合物及其在抗腺病毒7型中的应用 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3929582A1 (de) * | 1989-09-06 | 1991-03-07 | Hoechst Ag | Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament |
EP0556673B1 (de) * | 1992-02-15 | 1997-09-17 | Hoechst Aktiengesellschaft | Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
ATE139526T1 (de) * | 1992-02-15 | 1996-07-15 | Hoechst Ag | 3,5-substituierte benzoylguanidine, mit antiarrythmischer wirkung und inhibierender wirkung auf die proliferationen von zellen |
DK0577024T3 (no) * | 1992-07-01 | 1997-02-24 | Hoechst Ag | |
ES2097409T3 (es) * | 1992-09-22 | 1997-04-01 | Hoechst Ag | Benzoilguanidinas, procedimiento para su preparacion, asi como su empleo como antiarritmicos. |
TW250479B (no) * | 1992-12-15 | 1995-07-01 | Hoechst Ag | |
DE4404183A1 (de) * | 1994-02-10 | 1995-08-17 | Merck Patent Gmbh | 4-Amino-1-piperidylbenzoylguanidine |
DE4422685A1 (de) * | 1994-06-29 | 1996-01-04 | Hoechst Ag | Ortho-amino-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
-
1994
- 1994-08-28 DE DE4430212A patent/DE4430212A1/de not_active Withdrawn
-
1995
- 1995-07-25 TW TW084107705A patent/TW406067B/zh not_active IP Right Cessation
- 1995-08-18 DK DK95112998T patent/DK0704431T3/da active
- 1995-08-18 AT AT95112998T patent/ATE193282T1/de not_active IP Right Cessation
- 1995-08-18 PT PT95112998T patent/PT704431E/pt unknown
- 1995-08-18 ES ES95112998T patent/ES2147810T3/es not_active Expired - Lifetime
- 1995-08-18 DE DE59508383T patent/DE59508383D1/de not_active Expired - Fee Related
- 1995-08-18 EP EP95112998A patent/EP0704431B1/de not_active Expired - Lifetime
- 1995-08-21 AU AU30145/95A patent/AU703633B2/en not_active Ceased
- 1995-08-23 UA UA95083919A patent/UA44238C2/uk unknown
- 1995-08-25 CA CA002156959A patent/CA2156959A1/en not_active Abandoned
- 1995-08-25 NO NO953352A patent/NO305794B1/no not_active IP Right Cessation
- 1995-08-25 SK SK1054-95A patent/SK282202B6/sk unknown
- 1995-08-25 CZ CZ19952181A patent/CZ289492B6/cs not_active IP Right Cessation
- 1995-08-25 RU RU95114389/04A patent/RU2125981C1/ru not_active IP Right Cessation
- 1995-08-25 PL PL95310192A patent/PL181183B1/pl not_active IP Right Cessation
- 1995-08-25 CN CN95116623A patent/CN1068587C/zh not_active Expired - Fee Related
- 1995-08-25 HU HU9502500A patent/HUT74946A/hu unknown
- 1995-08-25 ZA ZA957161A patent/ZA957161B/xx unknown
- 1995-08-28 JP JP7240500A patent/JPH0859602A/ja active Pending
- 1995-08-28 BR BR9503817A patent/BR9503817A/pt not_active IP Right Cessation
- 1995-08-28 KR KR1019950026798A patent/KR100406686B1/ko not_active IP Right Cessation
- 1995-08-28 US US08/520,340 patent/US5849796A/en not_active Expired - Fee Related
-
2000
- 2000-07-21 GR GR20000401675T patent/GR3033989T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU3014595A (en) | 1996-03-14 |
RU2125981C1 (ru) | 1999-02-10 |
NO305794B1 (no) | 1999-07-26 |
SK282202B6 (sk) | 2001-12-03 |
SK105495A3 (en) | 1996-03-06 |
KR100406686B1 (ko) | 2004-07-19 |
EP0704431A2 (de) | 1996-04-03 |
ZA957161B (en) | 1996-04-17 |
DE59508383D1 (de) | 2000-06-29 |
DK0704431T3 (da) | 2000-09-11 |
HU9502500D0 (en) | 1995-10-30 |
PL310192A1 (en) | 1996-03-04 |
GR3033989T3 (en) | 2000-11-30 |
CZ218195A3 (en) | 1996-03-13 |
CZ289492B6 (cs) | 2002-02-13 |
ES2147810T3 (es) | 2000-10-01 |
AU703633B2 (en) | 1999-03-25 |
DE4430212A1 (de) | 1996-02-29 |
NO953352L (no) | 1996-02-29 |
PT704431E (pt) | 2000-10-31 |
EP0704431B1 (de) | 2000-05-24 |
CA2156959A1 (en) | 1996-03-01 |
CN1068587C (zh) | 2001-07-18 |
ATE193282T1 (de) | 2000-06-15 |
EP0704431A3 (de) | 1997-01-29 |
CN1125722A (zh) | 1996-07-03 |
BR9503817A (pt) | 1996-04-16 |
UA44238C2 (uk) | 2002-02-15 |
KR960007539A (ko) | 1996-03-22 |
JPH0859602A (ja) | 1996-03-05 |
US5849796A (en) | 1998-12-15 |
PL181183B1 (pl) | 2001-06-29 |
TW406067B (en) | 2000-09-21 |
HUT74946A (en) | 1997-03-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM1K | Lapsed by not paying the annual fees |