ES8601960A1 - Un procedimiento para la preparacion de nuevas 6h-dibenzo(b,e)(1,4)-oxatiepinas. - Google Patents

Un procedimiento para la preparacion de nuevas 6h-dibenzo(b,e)(1,4)-oxatiepinas.

Info

Publication number
ES8601960A1
ES8601960A1 ES536985A ES536985A ES8601960A1 ES 8601960 A1 ES8601960 A1 ES 8601960A1 ES 536985 A ES536985 A ES 536985A ES 536985 A ES536985 A ES 536985A ES 8601960 A1 ES8601960 A1 ES 8601960A1
Authority
ES
Spain
Prior art keywords
alkyl
alkylamino
mono
alkoxy
prostaglandin antagonists
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES536985A
Other languages
English (en)
Other versions
ES536985A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Frosst Canada and Co
Original Assignee
Merck Frosst Canada and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Frosst Canada and Co filed Critical Merck Frosst Canada and Co
Publication of ES8601960A1 publication Critical patent/ES8601960A1/es
Publication of ES536985A0 publication Critical patent/ES536985A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

UN PROCEDIMIENTO PARA LA PREPARACION DE 6H-DIBENZO (B,E) (1,4) OXATIEPINAS DE FORMULA (I) Y (II). CONSISTE EN OXIDAR UN COMPUESTO DE (II) PARA CONVERTIR EL SUSTITUYENTE HIDROXIMETILO EN UN SUSTITUYENTE CARBOXALDEHIDOS. LA OXIDACION SE REALIZA CON UN AGENTE OXIDANTE SELECCIONADO ENTRE CLOROCROMATO DE PIRIDINIO, CROMATO DE T-BUTILO, DICROMATO POTASICO, TETRAACETATO DE PLOMO Y 2,3 DICLORO-5,6-DICIANOQUINONA (DDQ). APLICADO EN EL TRATAMIENTO Y CONTROL DE CONDICIONES ALERGICAS TALES COMO EL ASMA ALERGICA.
ES536985A 1983-10-26 1984-10-22 Un procedimiento para la preparacion de nuevas 6h-dibenzo(b,e)(1,4)-oxatiepinas. Granted ES536985A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US54556483A 1983-10-26 1983-10-26

Publications (2)

Publication Number Publication Date
ES8601960A1 true ES8601960A1 (es) 1985-11-16
ES536985A0 ES536985A0 (es) 1985-11-16

Family

ID=24176735

Family Applications (1)

Application Number Title Priority Date Filing Date
ES536985A Granted ES536985A0 (es) 1983-10-26 1984-10-22 Un procedimiento para la preparacion de nuevas 6h-dibenzo(b,e)(1,4)-oxatiepinas.

Country Status (5)

Country Link
EP (1) EP0140784A2 (es)
JP (1) JPS60109587A (es)
CA (1) CA1241006A (es)
DK (1) DK509384A (es)
ES (1) ES536985A0 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4558037A (en) * 1984-06-04 1985-12-10 Merck & Co., Inc. Cardiovascular composition

Also Published As

Publication number Publication date
DK509384A (da) 1985-04-27
DK509384D0 (da) 1984-10-25
JPS60109587A (ja) 1985-06-15
EP0140784A2 (en) 1985-05-08
CA1241006A (en) 1988-08-23
ES536985A0 (es) 1985-11-16

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TH875EX (th) เบโซฟิวแรน ซัลฟาเมทส์