AR240938A2 - Un procedimiento para preparar un compuesto de imidazoquilina - Google Patents
Un procedimiento para preparar un compuesto de imidazoquilinaInfo
- Publication number
- AR240938A2 AR240938A2 AR29891784A AR29891784A AR240938A2 AR 240938 A2 AR240938 A2 AR 240938A2 AR 29891784 A AR29891784 A AR 29891784A AR 29891784 A AR29891784 A AR 29891784A AR 240938 A2 AR240938 A2 AR 240938A2
- Authority
- AR
- Argentina
- Prior art keywords
- formula
- compound
- reacted
- alkaline metal
- metal salt
- Prior art date
Links
- RHKWIGHJGOEUSM-UHFFFAOYSA-N 3h-imidazo[4,5-h]quinoline Chemical class C1=CN=C2C(N=CN3)=C3C=CC2=C1 RHKWIGHJGOEUSM-UHFFFAOYSA-N 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 3
- 150000002367 halogens Chemical group 0.000 abstract 2
- 239000002184 metal Substances 0.000 abstract 2
- -1 IMIDAZOQUINOLINE COMPOUND Chemical class 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical group [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 229940124669 imidazoquinoline Drugs 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
- H01L24/00—Arrangements for connecting or disconnecting semiconductor or solid-state bodies; Methods or apparatus related thereto
- H01L24/01—Means for bonding being attached to, or being formed on, the surface to be connected, e.g. chip-to-package, die-attach, "first-level" interconnects; Manufacturing methods related thereto
- H01L24/18—High density interconnect [HDI] connectors; Manufacturing methods related thereto
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
- H01L24/00—Arrangements for connecting or disconnecting semiconductor or solid-state bodies; Methods or apparatus related thereto
- H01L24/80—Methods for connecting semiconductor or other solid state bodies using means for bonding being attached to, or being formed on, the surface to be connected
- H01L24/82—Methods for connecting semiconductor or other solid state bodies using means for bonding being attached to, or being formed on, the surface to be connected by forming build-up interconnects at chip-level, e.g. for high density interconnects [HDI]
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
- H01L2224/00—Indexing scheme for arrangements for connecting or disconnecting semiconductor or solid-state bodies and methods related thereto as covered by H01L24/00
- H01L2224/01—Means for bonding being attached to, or being formed on, the surface to be connected, e.g. chip-to-package, die-attach, "first-level" interconnects; Manufacturing methods related thereto
- H01L2224/18—High density interconnect [HDI] connectors; Manufacturing methods related thereto
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
- H01L2924/00—Indexing scheme for arrangements or methods for connecting or disconnecting semiconductor or solid-state bodies as covered by H01L24/00
- H01L2924/01—Chemical elements
- H01L2924/01004—Beryllium [Be]
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
- H01L2924/00—Indexing scheme for arrangements or methods for connecting or disconnecting semiconductor or solid-state bodies as covered by H01L24/00
- H01L2924/01—Chemical elements
- H01L2924/01005—Boron [B]
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
- H01L2924/00—Indexing scheme for arrangements or methods for connecting or disconnecting semiconductor or solid-state bodies as covered by H01L24/00
- H01L2924/01—Chemical elements
- H01L2924/01006—Carbon [C]
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
- H01L2924/00—Indexing scheme for arrangements or methods for connecting or disconnecting semiconductor or solid-state bodies as covered by H01L24/00
- H01L2924/01—Chemical elements
- H01L2924/01011—Sodium [Na]
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
- H01L2924/00—Indexing scheme for arrangements or methods for connecting or disconnecting semiconductor or solid-state bodies as covered by H01L24/00
- H01L2924/01—Chemical elements
- H01L2924/01012—Magnesium [Mg]
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
- H01L2924/00—Indexing scheme for arrangements or methods for connecting or disconnecting semiconductor or solid-state bodies as covered by H01L24/00
- H01L2924/01—Chemical elements
- H01L2924/01013—Aluminum [Al]
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
- H01L2924/00—Indexing scheme for arrangements or methods for connecting or disconnecting semiconductor or solid-state bodies as covered by H01L24/00
- H01L2924/01—Chemical elements
- H01L2924/01015—Phosphorus [P]
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
- H01L2924/00—Indexing scheme for arrangements or methods for connecting or disconnecting semiconductor or solid-state bodies as covered by H01L24/00
- H01L2924/01—Chemical elements
- H01L2924/01018—Argon [Ar]
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
- H01L2924/00—Indexing scheme for arrangements or methods for connecting or disconnecting semiconductor or solid-state bodies as covered by H01L24/00
- H01L2924/01—Chemical elements
- H01L2924/01019—Potassium [K]
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
- H01L2924/00—Indexing scheme for arrangements or methods for connecting or disconnecting semiconductor or solid-state bodies as covered by H01L24/00
- H01L2924/01—Chemical elements
- H01L2924/0102—Calcium [Ca]
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
- H01L2924/00—Indexing scheme for arrangements or methods for connecting or disconnecting semiconductor or solid-state bodies as covered by H01L24/00
- H01L2924/01—Chemical elements
- H01L2924/01033—Arsenic [As]
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
- H01L2924/00—Indexing scheme for arrangements or methods for connecting or disconnecting semiconductor or solid-state bodies as covered by H01L24/00
- H01L2924/01—Chemical elements
- H01L2924/01067—Holmium [Ho]
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Power Engineering (AREA)
- Microelectronics & Electronic Packaging (AREA)
- Computer Hardware Design (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
UN PROCEDIMIENTO PARA PREPARAR UN COMPUESTO DE IMIDAZOQUINOLINA DE FORMULA I: EN DONDE LAS LINEAS PUNTEADAS INDICAN UN ENLACE DOBLE OPCIONAL AR ES UN GRUPO FENILO O HALOFENILO, O UNA SAL DE ADICION DEL MISMO ,SE HACE REACCIONAR UN COMPUESTO DE FORMULA II: EN DONDE AR ES COMO SE HA DEFINIDO ANTERIORMENTE Y X ES UN ATOMODE HALOGENO, CON UN TIOL DE FORMULA III:EN DONDE Y ES SH O UNA SAL DE METAL ALCALINO,O SE HACE REACCIONAR UN COMPUESTO DE FORMULA II DONDE X ES SH O UNA SAL DE METAL ALCALINO CON UN HALURO DE FORMULA III EN DONDE Y ES UN ATOMO DE HALOGENO, Y OPCIONALMENTE AISLAR EL PRODUCTO DE FORMULA I OBTENIDO COMO UNA BASE LIBRE O UNA SAL DE ADICION DEL MISMO
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB838333581A GB8333581D0 (en) | 1983-12-16 | 1983-12-16 | Heterocyclic compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AR240938A2 true AR240938A2 (es) | 1991-03-27 |
| AR240938A1 AR240938A1 (es) | 1991-03-27 |
Family
ID=10553400
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AR298917A AR240938A1 (es) | 1983-12-16 | 1984-12-11 | Un procedimiento para preparar un compuesto de imidazoquilina |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4609655A (es) |
| EP (1) | EP0146369B1 (es) |
| JP (1) | JPS60152486A (es) |
| KR (1) | KR910005852B1 (es) |
| AR (1) | AR240938A1 (es) |
| AT (1) | ATE38037T1 (es) |
| AU (1) | AU578055B2 (es) |
| CA (1) | CA1229598A (es) |
| DE (1) | DE3474664D1 (es) |
| DK (1) | DK168215B1 (es) |
| ES (2) | ES8604958A1 (es) |
| FI (1) | FI78092C (es) |
| GB (2) | GB8333581D0 (es) |
| GR (1) | GR82452B (es) |
| IE (1) | IE57647B1 (es) |
| PT (1) | PT79689A (es) |
| ZA (1) | ZA849484B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4761411A (en) * | 1983-05-18 | 1988-08-02 | Hoechst-Roussel Pharmaceuticals Inc. | Dihydrobenzopyrrolobenzodiazepines useful for treating pyschoses |
| IE57646B1 (en) * | 1983-12-16 | 1993-02-10 | Wyeth John & Brother Ltd | Derivatives of imidazoquinolines and analogues thereof |
| IL93136A (en) * | 1989-02-23 | 1995-01-24 | Janssen Pharmaceutica Nv | History of tetrahydroimidazo [1,4] benzodiazepine-2-thione, their preparation and pharmaceutical preparations containing them |
| JP2899757B2 (ja) * | 1989-06-26 | 1999-06-02 | 持田製薬株式会社 | ジヒドロイミダゾキノリノンオキシムスルホン酸誘導体 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3200123A (en) * | 1962-01-26 | 1965-08-10 | Richardson Merreil Inc | Imidazoquinolines |
| GB2039218B (en) * | 1978-11-30 | 1983-07-27 | Wyeth John & Brother Ltd | Pharmaceutical compositions |
| GB2069492B (en) * | 1980-02-20 | 1984-02-29 | Wyeth John & Brother Ltd | Sulphur compounds |
| US4409226A (en) * | 1981-10-05 | 1983-10-11 | Schering Corporation | Imidazo[1,5-a]pyridines |
| US4478834A (en) * | 1983-02-11 | 1984-10-23 | Usv Pharmaceutical Corporation | Dihydropyridines and their use in the treatment of asthma |
| IE57646B1 (en) * | 1983-12-16 | 1993-02-10 | Wyeth John & Brother Ltd | Derivatives of imidazoquinolines and analogues thereof |
-
1983
- 1983-12-16 GB GB838333581A patent/GB8333581D0/en active Pending
-
1984
- 1984-12-05 IE IE3119/84A patent/IE57647B1/en not_active IP Right Cessation
- 1984-12-05 ZA ZA849484A patent/ZA849484B/xx unknown
- 1984-12-11 AR AR298917A patent/AR240938A1/es active
- 1984-12-12 CA CA000469937A patent/CA1229598A/en not_active Expired
- 1984-12-13 GR GR82452A patent/GR82452B/el unknown
- 1984-12-13 FI FI844932A patent/FI78092C/fi not_active IP Right Cessation
- 1984-12-14 AT AT84308763T patent/ATE38037T1/de not_active IP Right Cessation
- 1984-12-14 PT PT79689A patent/PT79689A/pt unknown
- 1984-12-14 DK DK602184A patent/DK168215B1/da not_active IP Right Cessation
- 1984-12-14 GB GB08431656A patent/GB2151619B/en not_active Expired
- 1984-12-14 EP EP84308763A patent/EP0146369B1/en not_active Expired
- 1984-12-14 AU AU36694/84A patent/AU578055B2/en not_active Ceased
- 1984-12-14 DE DE8484308763T patent/DE3474664D1/de not_active Expired
- 1984-12-14 ES ES538592A patent/ES8604958A1/es not_active Expired
- 1984-12-17 JP JP59267292A patent/JPS60152486A/ja active Granted
- 1984-12-17 KR KR1019840008018A patent/KR910005852B1/ko not_active IP Right Cessation
-
1985
- 1985-09-06 US US06/772,990 patent/US4609655A/en not_active Expired - Lifetime
- 1985-10-31 ES ES549071A patent/ES8609322A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ATE38037T1 (de) | 1988-11-15 |
| CA1229598A (en) | 1987-11-24 |
| DK602184A (da) | 1985-06-17 |
| AU3669484A (en) | 1985-06-20 |
| KR910005852B1 (ko) | 1991-08-05 |
| GB2151619B (en) | 1987-01-21 |
| ES8609322A1 (es) | 1986-09-01 |
| FI78092B (fi) | 1989-02-28 |
| JPS60152486A (ja) | 1985-08-10 |
| DE3474664D1 (de) | 1988-11-24 |
| AU578055B2 (en) | 1988-10-13 |
| EP0146369A2 (en) | 1985-06-26 |
| GB8333581D0 (en) | 1984-01-25 |
| EP0146369A3 (en) | 1986-04-16 |
| GB8431656D0 (en) | 1985-01-30 |
| IE57647B1 (en) | 1993-02-10 |
| ES549071A0 (es) | 1986-09-01 |
| DK602184D0 (da) | 1984-12-14 |
| JPH0449554B2 (es) | 1992-08-11 |
| FI844932A0 (fi) | 1984-12-13 |
| ES8604958A1 (es) | 1986-03-01 |
| IE843119L (en) | 1985-06-16 |
| GB2151619A (en) | 1985-07-24 |
| DK168215B1 (da) | 1994-02-28 |
| KR850004760A (ko) | 1985-07-27 |
| PT79689A (en) | 1985-01-01 |
| FI844932L (fi) | 1985-06-17 |
| EP0146369B1 (en) | 1988-10-19 |
| AR240938A1 (es) | 1991-03-27 |
| FI78092C (fi) | 1989-06-12 |
| US4609655A (en) | 1986-09-02 |
| GR82452B (en) | 1985-03-19 |
| ES538592A0 (es) | 1986-03-01 |
| ZA849484B (en) | 1986-07-30 |
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