ES2035777B1 - Un procedimiento para preparar derivados de pirrolo-piridina. - Google Patents

Un procedimiento para preparar derivados de pirrolo-piridina.

Info

Publication number
ES2035777B1
ES2035777B1 ES9101378A ES9101378A ES2035777B1 ES 2035777 B1 ES2035777 B1 ES 2035777B1 ES 9101378 A ES9101378 A ES 9101378A ES 9101378 A ES9101378 A ES 9101378A ES 2035777 B1 ES2035777 B1 ES 2035777B1
Authority
ES
Spain
Prior art keywords
procedure
derivatives
preparing
pyramine
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES9101378A
Other languages
English (en)
Other versions
ES2035777A1 (es
Inventor
Andre Esanu
Pierre Braquet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ipsen Pharma SAS
Original Assignee
Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS filed Critical Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Publication of ES2035777A1 publication Critical patent/ES2035777A1/es
Application granted granted Critical
Publication of ES2035777B1 publication Critical patent/ES2035777B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR DERIVADOS DE PIRROLO-PIRAMINA DE FORMULA: FORMULA DONDE R REPRESENTA UN GRUPO FENILO, OPCIONALMENTE SUSTITUIDO CON UNO O MAS DE DIVERSOS GRUPOS Y LAS SALES TERAPEUTICAMENTE ACEPTABLES DE ESTOS COMPUESTOS, CUYO PROCEDIMIENTO COMPRENDE HACER REACCIONAR, EN UNA ATMOSFERA INERTE Y EN INSOLVENTE PROTICO, 2-METIL-3-HIDROXI-4,5-DIBROMOMETIL-PIRAMINA CON UN EXCESO ESTEQUIOMETRICO DEL COMPUESTO DE FORMULA NHSI2-R. LOS COMPUESTOS PREPARADOS SEGUN EL PROCEDIMIENTO DEFINIDO ARRIBA TIENEN ACTIVIDAD ANTIALERGICA.
ES9101378A 1990-06-09 1991-06-07 Un procedimiento para preparar derivados de pirrolo-piridina. Expired - Fee Related ES2035777B1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909012926A GB9012926D0 (en) 1990-06-09 1990-06-09 Pyrrolo-pyridine derivatives

Publications (2)

Publication Number Publication Date
ES2035777A1 ES2035777A1 (es) 1993-04-16
ES2035777B1 true ES2035777B1 (es) 1994-02-01

Family

ID=10677383

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9101378A Expired - Fee Related ES2035777B1 (es) 1990-06-09 1991-06-07 Un procedimiento para preparar derivados de pirrolo-piridina.

Country Status (15)

Country Link
US (1) US5168098A (es)
JP (1) JPH04243880A (es)
BE (1) BE1004762A3 (es)
CA (1) CA2043860C (es)
CH (1) CH682234A5 (es)
DE (1) DE4118817C2 (es)
ES (1) ES2035777B1 (es)
FR (2) FR2662941B1 (es)
GB (1) GB9012926D0 (es)
HK (1) HK33394A (es)
IE (1) IE65892B1 (es)
IT (1) IT1247983B (es)
LU (1) LU87947A1 (es)
NL (1) NL9100941A (es)
ZA (1) ZA914167B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0202671A3 (en) * 1999-09-13 2005-01-28 Bridge Pharma Inc Sarasota Optically active isomers of ketotifen and therapeutically active metabolites thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2767191A (en) * 1953-12-31 1956-10-16 American Cyanamid Co Dihydropyrrolo-pyridines
DE2711655A1 (de) * 1977-03-17 1978-09-21 Basf Ag Pyridinyl-aminoalkylaether
JPH01238527A (ja) * 1988-03-17 1989-09-22 Momotani Jiyuntenkan:Kk ヒアルロニダーゼ阻害剤

Also Published As

Publication number Publication date
US5168098A (en) 1992-12-01
CA2043860C (en) 1996-05-21
LU87947A1 (fr) 1992-03-03
CA2043860A1 (en) 1991-12-10
ITMI911535A1 (it) 1992-12-05
FR2663031A1 (fr) 1991-12-13
DE4118817C2 (de) 2001-11-15
HK33394A (en) 1994-04-22
JPH04243880A (ja) 1992-08-31
CH682234A5 (es) 1993-08-13
FR2662941B1 (fr) 1993-01-15
FR2662941A1 (fr) 1991-12-13
IE911951A1 (en) 1991-12-18
GB9012926D0 (en) 1990-08-01
ES2035777A1 (es) 1993-04-16
NL9100941A (nl) 1992-01-02
ITMI911535A0 (it) 1991-06-05
ZA914167B (en) 1992-03-25
BE1004762A3 (fr) 1993-01-26
IE65892B1 (en) 1995-11-29
FR2663031B1 (fr) 1993-01-15
DE4118817A1 (de) 1991-12-12
IT1247983B (it) 1995-01-05

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20050608