NO940635L - - Google Patents

Info

Publication number
NO940635L
NO940635L NO940635A NO940635A NO940635L NO 940635 L NO940635 L NO 940635L NO 940635 A NO940635 A NO 940635A NO 940635 A NO940635 A NO 940635A NO 940635 L NO940635 L NO 940635L
Authority
NO
Norway
Prior art keywords
sub
compound
enzyme
sulphate
steroid sulphatase
Prior art date
Application number
NO940635A
Other languages
English (en)
Norwegian (no)
Other versions
NO940635D0 (no
NO307301B1 (no
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of NO940635D0 publication Critical patent/NO940635D0/no
Publication of NO940635L publication Critical patent/NO940635L/no
Publication of NO307301B1 publication Critical patent/NO307301B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/36—Antigestagens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Surgical Instruments (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO940635A 1991-08-29 1994-02-24 Anvendelse av en forbindelse for fremstilling av et medikament for å inhibere steroidsulfataseaktivitet NO307301B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919118478A GB9118478D0 (en) 1991-08-29 1991-08-29 Steroid sulphatase inhibitors
PCT/GB1992/001587 WO1993005064A1 (en) 1991-08-29 1992-08-28 Steroid sulphatase inhibitors

Publications (3)

Publication Number Publication Date
NO940635D0 NO940635D0 (no) 1994-02-24
NO940635L true NO940635L (da) 1994-04-29
NO307301B1 NO307301B1 (no) 2000-03-13

Family

ID=10700604

Family Applications (6)

Application Number Title Priority Date Filing Date
NO940635A NO307301B1 (no) 1991-08-29 1994-02-24 Anvendelse av en forbindelse for fremstilling av et medikament for å inhibere steroidsulfataseaktivitet
NO995076A NO308774B1 (no) 1991-08-29 1999-10-18 Farmasøytisk preparat
NO995075A NO308903B1 (no) 1991-08-29 1999-10-18 Steroid-sulfataseinhibitorer
NO20002595A NO314287B1 (no) 1991-08-29 2000-05-19 Anvendelse av en ringsystemforbindelse for fremstilling av et medikament
NO20025725A NO318009B1 (no) 1991-08-29 2002-11-28 Forbindelse, farmasoytisk preparat inneholdende den samme samt anvendelse derav
NO20044458A NO20044458L (no) 1991-08-29 2004-10-20 Anvendelse av en ringsystemforbindelse for fremstilling av et medikament

Family Applications After (5)

Application Number Title Priority Date Filing Date
NO995076A NO308774B1 (no) 1991-08-29 1999-10-18 Farmasøytisk preparat
NO995075A NO308903B1 (no) 1991-08-29 1999-10-18 Steroid-sulfataseinhibitorer
NO20002595A NO314287B1 (no) 1991-08-29 2000-05-19 Anvendelse av en ringsystemforbindelse for fremstilling av et medikament
NO20025725A NO318009B1 (no) 1991-08-29 2002-11-28 Forbindelse, farmasoytisk preparat inneholdende den samme samt anvendelse derav
NO20044458A NO20044458L (no) 1991-08-29 2004-10-20 Anvendelse av en ringsystemforbindelse for fremstilling av et medikament

Country Status (26)

Country Link
US (3) US5616574A (da)
EP (6) EP0928609B1 (da)
JP (6) JP3219408B2 (da)
KR (4) KR100258396B1 (da)
AT (5) ATE237333T1 (da)
AU (2) AU689043B2 (da)
BR (1) BR9206434A (da)
CA (4) CA2305749A1 (da)
CY (4) CY2253B1 (da)
CZ (1) CZ295939B6 (da)
DE (5) DE69233431T2 (da)
DK (4) DK0921130T3 (da)
ES (4) ES2193475T3 (da)
FI (5) FI940903A (da)
GB (1) GB9118478D0 (da)
GE (6) GEP20022766B (da)
GR (1) GR3034579T3 (da)
HK (3) HK1019753A1 (da)
HU (1) HUT66097A (da)
LV (1) LV12618B (da)
NO (6) NO307301B1 (da)
RU (4) RU2001125673A (da)
SG (7) SG115508A1 (da)
SK (4) SK282186B6 (da)
UA (4) UA41875C2 (da)
WO (1) WO1993005064A1 (da)

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US6011024A (en) * 1991-08-28 2000-01-04 Imperial College Of Science Technology & Medicine Steroid sulphatase inhibitors
GB9118478D0 (en) * 1991-08-29 1991-10-16 Imperial College Steroid sulphatase inhibitors
GB9604709D0 (en) * 1996-03-05 1996-05-01 Imperial College A compound
US6476011B1 (en) 1991-08-28 2002-11-05 Sterix Limited Methods for introducing an estrogenic compound
GB9625334D0 (en) * 1996-12-05 1997-01-22 Imperial College Compound
GB9603325D0 (en) * 1996-02-16 1996-04-17 Imperial College A compound
US6903084B2 (en) 1991-08-29 2005-06-07 Sterix Limited Steroid sulphatase inhibitors
DE69531048T2 (de) * 1994-04-05 2004-05-06 Celltech Therapeutics Ltd., Slough Verwendung von steroidsulphatase-hemmern
DE4429398C2 (de) * 1994-08-09 1997-09-11 Jenapharm Gmbh Verwendung von Estra-1,3,5(10)-trien-Derivaten zur hormonalen Kontrazeption
DE4429397C2 (de) * 1994-08-09 2003-11-20 Jenapharm Gmbh Estra-1,3,5(10)-trien-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
GB9422777D0 (en) * 1994-11-11 1995-01-04 Imperial College Assay
US5571933A (en) * 1994-11-17 1996-11-05 Duquesne University Of The Holy Ghost Derivatives of estra 1,3,5(10)triene-17-one, 3-amino compounds and their use
US5705495A (en) * 1995-10-19 1998-01-06 Jenapharm Gmbh & Co. Kg. Sulfamate derivatives of 1,3,5(10)-estratriene derivatives, methods for their production and pharmaceuticals containing these compounds
US6921776B1 (en) 1996-02-16 2005-07-26 Sterix Limited Compound
US6506792B1 (en) 1997-03-04 2003-01-14 Sterix Limited Compounds that inhibit oestrone sulphatase and/or aromatase and methods for making and using
ATE286038T1 (de) * 1996-03-05 2005-01-15 Sterix Ltd Verbindungen mit sulfonsäure-amidgruppe
WO1998011124A1 (fr) * 1996-09-12 1998-03-19 Teikoku Hormone Mfg. Co., Ltd. Derives d'oestrariene a trisubstitution-d-homo-1,3,5,(10)
US20040127473A1 (en) * 1996-12-05 2004-07-01 Reed Michael John Compound
WO1999064013A1 (en) * 1998-06-10 1999-12-16 Sterix Limited Pharmaceutical composition with tumor necrosis factor a and 2-methoxyestrone-3-o-sulphamate for inhibition of estrone sulphatase
US6642220B1 (en) 1996-12-05 2003-11-04 Sterix Limited Compounds that inhibit oestrone sulphatase; compositions thereof; and methods employing the same
US5763432A (en) * 1997-01-29 1998-06-09 Sri International Steriod inhibitors of estrone sulfatase and associated pharmaceutical compositions and methods of use
DE19712488A1 (de) 1997-03-25 1998-10-01 Knoell Hans Forschung Ev Steroidsulfamate, Verfahren zu ihrer Herstellung und Anwendung derselben
GB9708716D0 (en) * 1997-04-29 1997-06-18 Imperial College Chronic heart failure
US6288050B1 (en) * 1997-07-18 2001-09-11 Duquesne University Of The Holy Ghost Steroid sulfatase inhibitors and methods for making and using the same
US5880115A (en) * 1997-07-18 1999-03-09 Duquesne University Of The Holy Ghost Steroid sulfatase inhibitors and methods for making and using the same
US6376687B1 (en) 1997-07-18 2002-04-23 Duquesne University Of The Holy Ghost Steroid sulfatase inhibitors and methods for making and using the same
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GB2331987B (en) * 1997-12-04 2002-11-27 Imperial College Polycyclic sulphamate inhibitors of oestrone sulphatase
US6046186A (en) * 1997-12-24 2000-04-04 Sri International Estrone sulfamate inhibitors of estrone sulfatase, and associated pharmaceutical compositions and methods of use
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CA2330611A1 (en) 1998-05-22 1999-12-02 The Board Of Trustees Of The Leland Stanford Junior University Bifunctional molecules and therapies based thereon
US6248780B1 (en) 1998-10-01 2001-06-19 Duquesne University Of The Holy Ghost Compounds for the treatment of estrogen-dependent illnesses and methods for making and using the same
US6667299B1 (en) 2000-03-16 2003-12-23 Hollis-Eden Pharmaceuticals, Inc. Pharmaceutical compositions and treatment methods
WO2000053620A1 (fr) * 1999-03-10 2000-09-14 Nippon Organon K. K. Nouveaux derives d'oestradiol
JP2000309599A (ja) 1999-04-13 2000-11-07 Kyowa Hakko Kogyo Co Ltd エストラ−１，３，５（１０），１６−テトラエン誘導体
AU2005225148B2 (en) * 1999-04-30 2008-04-03 Sterix Limited Use
IL145995A0 (en) * 1999-04-30 2002-07-25 Sterix Ltd Use
US7078395B1 (en) 1999-06-16 2006-07-18 Sterix Limited Methods for treating or preventing cancer by preventing, inhibiting or arresting cell cycling
GB9913536D0 (en) * 1999-06-10 1999-08-11 Sterix Ltd Use
US6583130B1 (en) 1999-09-13 2003-06-24 Schering Ag C13-substituted estra-1,3,5,(10)-trien-3-yl sulfamates, methods of preparing same, and pharmaceutical compositions containing these compounds
AU2190601A (en) * 1999-12-13 2001-06-25 Sterix Limited Halogenated sulphamate-, phosphonate-, thiophosphonate-, sulphonate- and sulphonamide- compounds as inhibitors of steroid sulphatase
US7335650B2 (en) 2000-01-14 2008-02-26 Sterix Limited Composition
WO2001081364A1 (fr) * 2000-04-24 2001-11-01 Kyowa Hakko Kogyo Co., Ltd. Derives d'estra-1,3,5(10)-triene
DE10027887A1 (de) * 2000-05-31 2001-12-13 Jenapharm Gmbh Verbindungen mit einer Sulfonamidgruppe und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
GB0020498D0 (en) * 2000-08-18 2000-10-11 Sterix Ltd Compound
WO2003006027A1 (en) * 2001-07-13 2003-01-23 Schering Aktiengesellschaft Combination of drospirenone and an estrogen sulphamate for hrt
ATE445838T1 (de) 2001-07-25 2009-10-15 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
DE10139494A1 (de) * 2001-08-13 2003-03-06 Jenapharm Gmbh Antitumor wirksame 2-Alkoxyestradiolsulfamate
US8026229B2 (en) 2001-08-13 2011-09-27 Sterix Limited Antitumor-active 2-alkoxyestradiol sulfamates
PT1448592E (pt) * 2001-10-18 2006-07-31 Sterix Ltd Compostos esteroides para inibicao da esteroide sulfatase
DE60229009D1 (de) 2001-10-18 2008-10-30 Sterix Ltd Steroidale Verbindungen zur Hemmung von steroid Sulfotase
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DE10307105A1 (de) * 2003-02-19 2004-09-09 Schering Ag Antitumor wirksame 2-substituierte 18a-Homoestra-1,3,5(10)-trien-3-yl sulfamate
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DK1889198T3 (da) 2005-04-28 2015-02-09 Proteus Digital Health Inc Farma-informatiksystem
US8030298B2 (en) 2005-05-26 2011-10-04 Abbott Products Gmbh 17β-HSD1 and STS inhibitors
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ES2728225T3 (es) 2009-02-20 2019-10-23 2 Bbb Medicines B V Sistema de administración de fármacos a base de glutatión
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GB9118465D0 (en) * 1991-08-29 1991-10-16 Imperial College Steroid sulphatase inhibitors
US5571933A (en) * 1994-11-17 1996-11-05 Duquesne University Of The Holy Ghost Derivatives of estra 1,3,5(10)triene-17-one, 3-amino compounds and their use
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Also Published As

Publication number Publication date
FI20002259A (fi) 2000-10-13
DE69233020D1 (de) 2003-05-22
DE69233431D1 (de) 2004-11-11
DK0641355T3 (da) 2000-10-09
NO995076L (no) 1994-04-29
FI20002260A (fi) 2000-10-13
UA70956C2 (uk) 2004-11-15
RU2210574C2 (ru) 2003-08-20
HK1025051A1 (en) 2000-11-03
EP0641355A1 (en) 1995-03-08
SK282189B6 (sk) 2001-12-03
EP0982032A3 (en) 2002-03-20
RU2001125673A (ru) 2003-06-27
GEP20022802B (en) 2002-09-25
CZ44094A3 (en) 1995-01-18
RU94019334A (ru) 1996-10-20
UA70958C2 (uk) 2004-11-15
JP3219408B2 (ja) 2001-10-15
NO940635D0 (no) 1994-02-24
US6159960A (en) 2000-12-12
NO20025725D0 (no) 2002-11-28
NO2595A (no) 1994-04-29
EP1099706A3 (en) 2002-09-04
HK1019753A1 (en) 2000-02-25
JP3581820B2 (ja) 2004-10-27
ATE246706T1 (de) 2003-08-15
JP2003176297A (ja) 2003-06-24
FI940903A (fi) 1994-04-20
CY2253B1 (en) 2003-07-04
CZ295939B6 (cs) 2005-12-14
EP0921130B1 (en) 2003-05-07
WO1993005064A1 (en) 1993-03-18
AU2490592A (en) 1993-04-05
CY2394B1 (en) 2004-09-10
SG73391A1 (en) 2006-08-30
SG88782A1 (en) 2002-05-21
EP0928609A2 (en) 1999-07-14
GEP20022803B (en) 2002-09-25
NO318009B1 (no) 2005-01-17
SG103374A1 (en) 2004-04-29
DE69233053D1 (de) 2003-06-12
ES2196483T3 (es) 2003-12-16
SG88783A1 (en) 2002-05-21
FI940903A0 (fi) 1994-02-25
SG103820A1 (en) 2004-05-26
EP1522543A1 (en) 2005-04-13
UA70957C2 (uk) 2004-11-15
EP0928609A3 (en) 2001-11-07
AU1007799A (en) 1999-03-04
JP2000038341A (ja) 2000-02-08
CA2114630C (en) 2003-09-30
AU668882B2 (en) 1996-05-23
AU5837396A (en) 1996-09-05
EP1099706B1 (en) 2004-10-06
EP0982032A2 (en) 2000-03-01
ATE237333T1 (de) 2003-05-15
EP0641355B1 (en) 2000-07-19
LV12618B (en) 2001-07-20
GEP20022766B (en) 2002-08-26
ATE278704T1 (de) 2004-10-15
CY2398B1 (en) 2004-09-10
US5830886A (en) 1998-11-03
DE69233149D1 (de) 2003-09-11
EP0928609B1 (en) 2003-04-16
EP0982032B1 (en) 2003-08-06
NO20044458L (no) 1994-04-29
DE69231280D1 (de) 2000-08-24
DE69233053T2 (de) 2003-11-20
FI20050991A (fi) 2005-10-03
NO20025725L (no) 1994-04-29
NO20002595D0 (no) 2000-05-19
DE69233431T2 (de) 2006-02-23
ES2193475T3 (es) 2003-11-01
DK0982032T3 (da) 2003-11-03
GEP20022637B (en) 2002-02-25
JP2002255993A (ja) 2002-09-11
CY2397B1 (en) 2004-09-10
SK282186B6 (sk) 2001-12-03
ES2148178T3 (es) 2000-10-16
RU2182152C2 (ru) 2002-05-10
DE69233149T2 (de) 2004-06-24
NO308903B1 (no) 2000-11-13
JP2000355542A (ja) 2000-12-26
US5616574A (en) 1997-04-01
UA41875C2 (uk) 2001-10-15
GR3034579T3 (en) 2001-01-31
NO995076D0 (no) 1999-10-18
ATE194843T1 (de) 2000-08-15
GEP20063773B (en) 2006-03-27
GB9118478D0 (en) 1991-10-16
GEP20033094B (en) 2003-10-27
ATE239753T1 (de) 2003-05-15
NO314287B1 (no) 2003-03-03
DE69231280T2 (de) 2000-11-30
AU689043B2 (en) 1998-03-19
JP3581802B2 (ja) 2004-10-27
RU2207134C2 (ru) 2003-06-27
HK1020672A1 (en) 2000-05-19
SG106116A1 (en) 2004-09-30
CA2305749A1 (en) 1993-03-18
CA2305767A1 (en) 1993-03-18
DK0928609T3 (da) 2003-07-21
EP0921130A3 (en) 2001-09-05
NO308774B1 (no) 2000-10-30
KR100258396B1 (ko) 2000-08-01
NO307301B1 (no) 2000-03-13
SK24694A3 (en) 1994-11-09
FI20002261A (fi) 2000-10-13
LV12618A (en) 2001-02-20
BR9206434A (pt) 1994-09-27
JPH07501515A (ja) 1995-02-16
DK0921130T3 (da) 2003-07-21
ES2204059T3 (es) 2004-04-16
EP0921130A2 (en) 1999-06-09
EP1099706A2 (en) 2001-05-16
CA2305758A1 (en) 1993-03-18
HUT66097A (en) 1994-09-28
DE69233020T2 (de) 2003-11-06
CA2114630A1 (en) 1993-03-18
NO995075L (no) 1994-04-29
HU9400583D0 (en) 1994-05-30
SK282187B6 (sk) 2001-12-03
SK282188B6 (sk) 2001-12-03
NO995075D0 (no) 1999-10-18
JP3581821B2 (ja) 2004-10-27
KR100321019B1 (ko) 2002-03-20
JP2000355598A (ja) 2000-12-26
AU717116B2 (en) 2000-03-16
KR100321018B1 (ko) 2002-03-20
SG115508A1 (en) 2005-10-28
KR100322650B1 (ko) 2002-03-20

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