NO893168D0 - Antipsykotiske 3-piperazinylbenzazol-derivater. - Google Patents

Antipsykotiske 3-piperazinylbenzazol-derivater.

Info

Publication number
NO893168D0
NO893168D0 NO893168A NO893168A NO893168D0 NO 893168 D0 NO893168 D0 NO 893168D0 NO 893168 A NO893168 A NO 893168A NO 893168 A NO893168 A NO 893168A NO 893168 D0 NO893168 D0 NO 893168D0
Authority
NO
Norway
Prior art keywords
compounds
piperazinylbenzazole
antipsycotic
derivatives
6alkyl
Prior art date
Application number
NO893168A
Other languages
English (en)
Other versions
NO176051C (no
NO176051B (no
NO893168L (no
Inventor
Ludo Edmond Josephine Kennis
Jan Vandenberk
Josephus Carolus Mertens
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of NO893168D0 publication Critical patent/NO893168D0/no
Publication of NO893168L publication Critical patent/NO893168L/no
Publication of NO176051B publication Critical patent/NO176051B/no
Publication of NO176051C publication Critical patent/NO176051C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56Benzopyrazoles; Hydrogenated benzopyrazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
NO893168A 1988-08-05 1989-08-04 Analogifremgangsmåte for fremstilling av terapeutisk aktive 3-piperazinylbenzazol-derivater NO176051C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US22841788A 1988-08-05 1988-08-05

Publications (4)

Publication Number Publication Date
NO893168D0 true NO893168D0 (no) 1989-08-04
NO893168L NO893168L (no) 1990-02-06
NO176051B NO176051B (no) 1994-10-17
NO176051C NO176051C (no) 1995-01-25

Family

ID=22857091

Family Applications (1)

Application Number Title Priority Date Filing Date
NO893168A NO176051C (no) 1988-08-05 1989-08-04 Analogifremgangsmåte for fremstilling av terapeutisk aktive 3-piperazinylbenzazol-derivater

Country Status (20)

Country Link
EP (1) EP0353821B1 (no)
JP (1) JP2779216B2 (no)
KR (1) KR0145706B1 (no)
CN (1) CN1023602C (no)
AT (1) ATE122348T1 (no)
AU (1) AU619877B2 (no)
CA (1) CA1331609C (no)
DE (1) DE68922537T2 (no)
DK (1) DK175124B1 (no)
ES (1) ES2074462T3 (no)
FI (1) FI90238C (no)
HU (1) HU206341B (no)
IE (1) IE66198B1 (no)
IL (1) IL91194A (no)
NO (1) NO176051C (no)
NZ (1) NZ230045A (no)
PH (1) PH26550A (no)
PT (1) PT91364B (no)
SU (1) SU1687030A3 (no)
ZA (1) ZA895978B (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5364866A (en) 1989-05-19 1994-11-15 Hoechst-Roussel Pharmaceuticals, Inc. Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analetics
US5561128A (en) * 1989-05-19 1996-10-01 Hoechst-Roussel Pharmaceuticals, Inc. N-[(4-(heteroaryl)-1-piperidinyl)alkyl]-10,11-dihydro-5H-dibenz[B,F]azepines and related compounds and their therapeutic utility
US5776963A (en) * 1989-05-19 1998-07-07 Hoechst Marion Roussel, Inc. 3-(heteroaryl)-1- (2,3-dihydro-1h-isoindol-2-yl)alkyl!pyrrolidines and 3-(heteroaryl)-1- (2,3-dihydro-1h-indol-1-yl)alkyl!pyrrolidines and related compounds and their therapeutic untility
US4954503A (en) * 1989-09-11 1990-09-04 Hoechst-Roussel Pharmaceuticals, Inc. 3-(1-substituted-4-piperazinyl)-1H-indazoles
FR2671350A1 (fr) * 1991-01-08 1992-07-10 Adir Nouveaux derives de benzisoxazole et de benzisothiazole, leur procede de preparation, et les compositions pharmaceutiques les renfermant.
US5041445A (en) * 1990-05-21 1991-08-20 Hoechst-Roussel Pharmaceuticals Incorporated 3-[1-thiazolidinylbutyl-4-piperazinyl]-1H-indazoles
PL170889B1 (pl) * 1991-09-25 1997-02-28 Pfizer S posób wytwarzania nowej (7S,9aS)-2-(benzo[d]izoksazoliio-3) perhydro-7-{2-[(2aS)-2a- hydroksy-3,3- czterometylenogluta-rimido]etyio}-1H-pirydo[1,2-a] pirazyny i nowej(7S,9aS)-2-(benzo[d]izoksazolilo-3) perhydro-7-{2[(2aR)-2a-hydroksy-3,3- czterometylenoglutarimido]-etylo}-1 H-pirydo[1,2-a] pirazyny PL PL
GB9202915D0 (en) * 1992-02-12 1992-03-25 Wellcome Found Chemical compounds
KR0179063B1 (ko) * 1993-02-04 1999-03-20 사사이 아키라 항정신병 작용을 갖는 화합물
WO1996016968A1 (fr) * 1994-11-25 1996-06-06 Meiji Seika Kabushiki Kaisha Compose thiazole bicyclique
US6187774B1 (en) * 1996-03-04 2001-02-13 Yoshitomi Pharmaceutical Industries, Ltd. Fused heterocyclic compounds and pharmaceutical applications thereof
JP4303969B2 (ja) 2001-03-29 2009-07-29 シェーリング コーポレイション Ccr5アンタゴニストとして有用なアリールオキシム−ピペラジン
BRPI0919342A2 (pt) * 2008-09-23 2015-12-29 Hoffmann La Roche derivados do isoxazol [4,5] piridin-3-il-piperazina, seu processo de preparação, seu medicamento e seu uso
US11676855B2 (en) * 2020-02-26 2023-06-13 Taiwan Semiconductor Manufacturing Co., Ltd. Patterning interconnects and other structures by photo-sensitizing method
CN114634479A (zh) * 2020-12-16 2022-06-17 北京盈科瑞创新药物研究有限公司 一种派嗪衍生物、其制备方法及应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4411901A (en) * 1981-12-23 1983-10-25 Mead Johnson & Company Benzisothiazole and benzisoxazole piperazine derivatives
US4452799A (en) 1981-12-23 1984-06-05 Mead Johnson & Company Benzisothiazole and benzisoxazole piperazine derivatives
HU198036B (en) * 1983-08-22 1989-07-28 Hoechst Roussel Pharma Process for production of derivatives of 3-piperidil-/1h/-indasole and medical preparatives containing them
US4524206A (en) 1983-09-12 1985-06-18 Mead Johnson & Company 1-Heteroaryl-4-(2,5-pyrrolidinedion-1-yl)alkyl)piperazine derivatives
US4590196A (en) 1984-08-23 1986-05-20 Bristol-Myers Company Analgesic 1,2-benzisothiazol-3-ylpiperazine derivatives
US4804663A (en) 1985-03-27 1989-02-14 Janssen Pharmaceutica N.V. 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles
EP0302423A3 (en) 1987-08-07 1991-01-09 Hoechst-Roussel Pharmaceuticals Incorporated 1-phenyl-3-(1-piperazinyl)-1h-indazoles, a process and intermediates for their preparation, and the use thereof as medicaments

Also Published As

Publication number Publication date
NO176051C (no) 1995-01-25
FI893701A0 (fi) 1989-08-04
AU619877B2 (en) 1992-02-06
IL91194A (en) 1994-04-12
NZ230045A (en) 1990-11-27
CN1040194A (zh) 1990-03-07
EP0353821A3 (en) 1991-07-17
FI90238C (fi) 1994-01-10
JPH0288572A (ja) 1990-03-28
NO176051B (no) 1994-10-17
AU3917189A (en) 1990-03-08
ES2074462T3 (es) 1995-09-16
KR0145706B1 (ko) 1998-08-17
CA1331609C (en) 1994-08-23
HUT55385A (en) 1991-05-28
FI90238B (fi) 1993-09-30
PT91364A (pt) 1990-03-08
DK383689D0 (da) 1989-08-04
ZA895978B (en) 1991-04-24
EP0353821A2 (en) 1990-02-07
DK175124B1 (da) 2004-06-07
DE68922537T2 (de) 1995-09-14
CN1023602C (zh) 1994-01-26
NO893168L (no) 1990-02-06
FI893701A (fi) 1990-02-06
DK383689A (da) 1990-02-06
ATE122348T1 (de) 1995-05-15
IL91194A0 (en) 1990-03-19
PH26550A (en) 1992-08-19
SU1687030A3 (ru) 1991-10-23
JP2779216B2 (ja) 1998-07-23
PT91364B (pt) 1995-03-31
IE892535L (en) 1990-02-05
EP0353821B1 (en) 1995-05-10
DE68922537D1 (de) 1995-06-14
KR900003155A (ko) 1990-03-23
IE66198B1 (en) 1995-12-13
HU206341B (en) 1992-10-28

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