PT91364A - Processo para a preparacao de derivados de 3-piperazinil-benzazol e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de derivados de 3-piperazinil-benzazol e de composicoes farmaceuticas que os contem

Info

Publication number
PT91364A
PT91364A PT91364A PT9136489A PT91364A PT 91364 A PT91364 A PT 91364A PT 91364 A PT91364 A PT 91364A PT 9136489 A PT9136489 A PT 9136489A PT 91364 A PT91364 A PT 91364A
Authority
PT
Portugal
Prior art keywords
pharmaceutical compositions
piperazinyl
compositions containing
preparation
compounds
Prior art date
Application number
PT91364A
Other languages
English (en)
Other versions
PT91364B (pt
Inventor
Ludo Edmond Josephine Kennis
Jan Vandenberk
Josephus Carolus Mertens
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of PT91364A publication Critical patent/PT91364A/pt
Publication of PT91364B publication Critical patent/PT91364B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56Benzopyrazoles; Hydrogenated benzopyrazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
PT91364A 1988-08-05 1989-08-03 Processo para a preparacao de derivados de 3-piperazinil-benzazol e de composicoes farmaceuticas que os contem PT91364B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US22841788A 1988-08-05 1988-08-05

Publications (2)

Publication Number Publication Date
PT91364A true PT91364A (pt) 1990-03-08
PT91364B PT91364B (pt) 1995-03-31

Family

ID=22857091

Family Applications (1)

Application Number Title Priority Date Filing Date
PT91364A PT91364B (pt) 1988-08-05 1989-08-03 Processo para a preparacao de derivados de 3-piperazinil-benzazol e de composicoes farmaceuticas que os contem

Country Status (20)

Country Link
EP (1) EP0353821B1 (pt)
JP (1) JP2779216B2 (pt)
KR (1) KR0145706B1 (pt)
CN (1) CN1023602C (pt)
AT (1) ATE122348T1 (pt)
AU (1) AU619877B2 (pt)
CA (1) CA1331609C (pt)
DE (1) DE68922537T2 (pt)
DK (1) DK175124B1 (pt)
ES (1) ES2074462T3 (pt)
FI (1) FI90238C (pt)
HU (1) HU206341B (pt)
IE (1) IE66198B1 (pt)
IL (1) IL91194A (pt)
NO (1) NO176051C (pt)
NZ (1) NZ230045A (pt)
PH (1) PH26550A (pt)
PT (1) PT91364B (pt)
SU (1) SU1687030A3 (pt)
ZA (1) ZA895978B (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5776963A (en) * 1989-05-19 1998-07-07 Hoechst Marion Roussel, Inc. 3-(heteroaryl)-1- (2,3-dihydro-1h-isoindol-2-yl)alkyl!pyrrolidines and 3-(heteroaryl)-1- (2,3-dihydro-1h-indol-1-yl)alkyl!pyrrolidines and related compounds and their therapeutic untility
US5561128A (en) * 1989-05-19 1996-10-01 Hoechst-Roussel Pharmaceuticals, Inc. N-[(4-(heteroaryl)-1-piperidinyl)alkyl]-10,11-dihydro-5H-dibenz[B,F]azepines and related compounds and their therapeutic utility
US5364866A (en) * 1989-05-19 1994-11-15 Hoechst-Roussel Pharmaceuticals, Inc. Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analetics
US4954503A (en) * 1989-09-11 1990-09-04 Hoechst-Roussel Pharmaceuticals, Inc. 3-(1-substituted-4-piperazinyl)-1H-indazoles
FR2671350A1 (fr) * 1991-01-08 1992-07-10 Adir Nouveaux derives de benzisoxazole et de benzisothiazole, leur procede de preparation, et les compositions pharmaceutiques les renfermant.
US5041445A (en) * 1990-05-21 1991-08-20 Hoechst-Roussel Pharmaceuticals Incorporated 3-[1-thiazolidinylbutyl-4-piperazinyl]-1H-indazoles
ES2096099T3 (es) * 1991-09-25 1997-03-01 Pfizer Perhidro-1h-pirido(1,2,a)pirazinas 2-sustituidas neurolepticas.
GB9202915D0 (en) * 1992-02-12 1992-03-25 Wellcome Found Chemical compounds
KR0179063B1 (ko) * 1993-02-04 1999-03-20 사사이 아키라 항정신병 작용을 갖는 화합물
EP0794185A4 (en) * 1994-11-25 1998-03-25 Meiji Seika Co BICYCLIC THIAZOLE COMPOUND
US6187774B1 (en) * 1996-03-04 2001-02-13 Yoshitomi Pharmaceutical Industries, Ltd. Fused heterocyclic compounds and pharmaceutical applications thereof
DE60230491D1 (de) * 2001-03-29 2009-02-05 Schering Corp Als ccr5-antagonisten verwendbare aryloxim-piperazine
CN102164927A (zh) * 2008-09-23 2011-08-24 弗·哈夫曼-拉罗切有限公司 用作多巴胺d3受体调节剂的异唑并[4,5]吡啶-3-基-哌嗪衍生物
US11676855B2 (en) * 2020-02-26 2023-06-13 Taiwan Semiconductor Manufacturing Co., Ltd. Patterning interconnects and other structures by photo-sensitizing method
CN114634479A (zh) * 2020-12-16 2022-06-17 北京盈科瑞创新药物研究有限公司 一种派嗪衍生物、其制备方法及应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4411901A (en) * 1981-12-23 1983-10-25 Mead Johnson & Company Benzisothiazole and benzisoxazole piperazine derivatives
US4452799A (en) 1981-12-23 1984-06-05 Mead Johnson & Company Benzisothiazole and benzisoxazole piperazine derivatives
HU198036B (en) 1983-08-22 1989-07-28 Hoechst Roussel Pharma Process for production of derivatives of 3-piperidil-/1h/-indasole and medical preparatives containing them
US4524206A (en) 1983-09-12 1985-06-18 Mead Johnson & Company 1-Heteroaryl-4-(2,5-pyrrolidinedion-1-yl)alkyl)piperazine derivatives
US4590196A (en) 1984-08-23 1986-05-20 Bristol-Myers Company Analgesic 1,2-benzisothiazol-3-ylpiperazine derivatives
US4804663A (en) 1985-03-27 1989-02-14 Janssen Pharmaceutica N.V. 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles
EP0302423A3 (en) 1987-08-07 1991-01-09 Hoechst-Roussel Pharmaceuticals Incorporated 1-phenyl-3-(1-piperazinyl)-1h-indazoles, a process and intermediates for their preparation, and the use thereof as medicaments

Also Published As

Publication number Publication date
DK383689D0 (da) 1989-08-04
FI90238C (fi) 1994-01-10
AU3917189A (en) 1990-03-08
FI893701A (fi) 1990-02-06
PT91364B (pt) 1995-03-31
CA1331609C (en) 1994-08-23
JPH0288572A (ja) 1990-03-28
DE68922537T2 (de) 1995-09-14
DK383689A (da) 1990-02-06
CN1023602C (zh) 1994-01-26
ES2074462T3 (es) 1995-09-16
NO893168L (no) 1990-02-06
DE68922537D1 (de) 1995-06-14
FI893701A0 (fi) 1989-08-04
NO176051B (no) 1994-10-17
ATE122348T1 (de) 1995-05-15
EP0353821B1 (en) 1995-05-10
JP2779216B2 (ja) 1998-07-23
ZA895978B (en) 1991-04-24
FI90238B (fi) 1993-09-30
NO893168D0 (no) 1989-08-04
CN1040194A (zh) 1990-03-07
AU619877B2 (en) 1992-02-06
IL91194A0 (en) 1990-03-19
HUT55385A (en) 1991-05-28
IE66198B1 (en) 1995-12-13
HU206341B (en) 1992-10-28
NZ230045A (en) 1990-11-27
EP0353821A3 (en) 1991-07-17
EP0353821A2 (en) 1990-02-07
PH26550A (en) 1992-08-19
SU1687030A3 (ru) 1991-10-23
NO176051C (no) 1995-01-25
IE892535L (en) 1990-02-05
DK175124B1 (da) 2004-06-07
KR900003155A (ko) 1990-03-23
IL91194A (en) 1994-04-12
KR0145706B1 (ko) 1998-08-17

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19940922

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20070322