NO332460B1 - Renset humant NOGO protein, fusjon- eller kimaert protein, isolert nukleinsyre, kloningsvektor, rekombinant celle, fremgangsmate for fremstilling av proteinet, samt anvendelse av proteinet for fremstilling av et medikament for behandling. - Google Patents

Renset humant NOGO protein, fusjon- eller kimaert protein, isolert nukleinsyre, kloningsvektor, rekombinant celle, fremgangsmate for fremstilling av proteinet, samt anvendelse av proteinet for fremstilling av et medikament for behandling. Download PDF

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Publication number
NO332460B1
NO332460B1 NO20012223A NO20012223A NO332460B1 NO 332460 B1 NO332460 B1 NO 332460B1 NO 20012223 A NO20012223 A NO 20012223A NO 20012223 A NO20012223 A NO 20012223A NO 332460 B1 NO332460 B1 NO 332460B1
Authority
NO
Norway
Prior art keywords
nogo
protein
nucleic acid
sequence
seq
Prior art date
Application number
NO20012223A
Other languages
English (en)
Norwegian (no)
Other versions
NO20012223L (no
NO20012223D0 (no
Inventor
Martin E Schwab
Maio S Chen
Original Assignee
Univ Zuerich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22316666&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO332460(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Zuerich filed Critical Univ Zuerich
Publication of NO20012223D0 publication Critical patent/NO20012223D0/no
Publication of NO20012223L publication Critical patent/NO20012223L/no
Publication of NO332460B1 publication Critical patent/NO332460B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
NO20012223A 1998-11-06 2001-05-04 Renset humant NOGO protein, fusjon- eller kimaert protein, isolert nukleinsyre, kloningsvektor, rekombinant celle, fremgangsmate for fremstilling av proteinet, samt anvendelse av proteinet for fremstilling av et medikament for behandling. NO332460B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10744698P 1998-11-06 1998-11-06
PCT/US1999/026160 WO2000031235A2 (en) 1998-11-06 1999-11-05 Nucleotide and protein sequences of nogo genes and methods based thereon

Publications (3)

Publication Number Publication Date
NO20012223D0 NO20012223D0 (no) 2001-05-04
NO20012223L NO20012223L (no) 2001-07-02
NO332460B1 true NO332460B1 (no) 2012-09-24

Family

ID=22316666

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20012223A NO332460B1 (no) 1998-11-06 2001-05-04 Renset humant NOGO protein, fusjon- eller kimaert protein, isolert nukleinsyre, kloningsvektor, rekombinant celle, fremgangsmate for fremstilling av proteinet, samt anvendelse av proteinet for fremstilling av et medikament for behandling.

Country Status (27)

Country Link
US (4) US7781188B1 (ru)
EP (3) EP2093294B1 (ru)
JP (2) JP2003531566A (ru)
KR (1) KR100728405B1 (ru)
CN (3) CN1721444A (ru)
AT (1) ATE435232T1 (ru)
AU (1) AU774367C (ru)
BR (1) BR9915137A (ru)
CA (1) CA2350395C (ru)
CY (1) CY1110679T1 (ru)
CZ (1) CZ304224B6 (ru)
DE (1) DE69941059D1 (ru)
DK (1) DK1124846T3 (ru)
ES (2) ES2529196T3 (ru)
HK (1) HK1038027A1 (ru)
HU (1) HUP0301829A3 (ru)
IL (3) IL142989A0 (ru)
MX (1) MXPA01004598A (ru)
NO (1) NO332460B1 (ru)
NZ (1) NZ511683A (ru)
PL (1) PL204293B1 (ru)
PT (1) PT1124846E (ru)
RU (3) RU2304585C2 (ru)
SK (1) SK287323B6 (ru)
TR (1) TR200700740T2 (ru)
WO (1) WO2000031235A2 (ru)
ZA (1) ZA200103714B (ru)

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US20020072493A1 (en) 1998-05-19 2002-06-13 Yeda Research And Development Co. Ltd. Activated T cells, nervous system-specific antigens and their uses
DK1098972T3 (da) * 1998-07-22 2011-01-03 Smithkline Beecham Ltd Protein med lighed med neuroendokrinspecifikt protein samt cDNA kodende derfor
AU774367C (en) 1998-11-06 2005-04-21 University Of Zurich Nucleotide and protein sequences of nogo genes and methods based thereon
WO2000060083A1 (en) * 1999-04-08 2000-10-12 Chiron Corporation Novel protein associated with cell stress response
US7186530B1 (en) 2000-04-07 2007-03-06 Chiron Corporation Protein associated with cell stress response
ES2341842T3 (es) * 2000-01-12 2010-06-29 Yale University Bloqueo del crecimiento axonal mediado por el receptor de nogo.
US7119165B2 (en) 2000-01-12 2006-10-10 Yale University Nogo receptor-mediated blockade of axonal growth
US7049395B2 (en) 2000-05-02 2006-05-23 Yale University Anti-inflammatory compounds and uses thereof
AU1153902A (en) * 2000-10-06 2002-04-15 Univ Yale Nogo receptor homologs
GB0101312D0 (en) * 2001-01-18 2001-02-28 Glaxo Group Ltd Assay
GB0101313D0 (en) * 2001-01-18 2001-02-28 Glaxo Group Ltd Assay
TWI323265B (en) 2002-08-06 2010-04-11 Glaxo Group Ltd Antibodies
GB0228832D0 (en) 2002-12-10 2003-01-15 Novartis Ag Organic compound
WO2004039836A1 (en) * 2002-10-31 2004-05-13 Pieris Proteolab Ag Soluble truncated polypeptides of the nogo-a protein
GB0306309D0 (en) 2003-03-19 2003-04-23 Glaxo Group Ltd Method of treatment
EA010055B1 (ru) 2003-03-19 2008-06-30 Байоджен Айдек Ма Инк. ВЫДЕЛЕННАЯ НУКЛЕИНОВАЯ КИСЛОТА, КОДИРУЮЩАЯ ПОЛИПЕПТИД Sp35, ПОЛИПЕПТИД Sp35 И СПОСОБЫ ПРИМЕНЕНИЯ НУКЛЕИНОВОЙ КИСЛОТЫ И ПОЛИПЕПТИДА
PL1711530T3 (pl) * 2003-12-22 2010-01-29 Glaxo Group Ltd Immunoglobuliny neutralizujące Nogo-A do leczenia chorób neurologicznych
KR101239542B1 (ko) 2004-06-24 2013-03-07 바이오겐 아이덱 엠에이 인코포레이티드 탈수초화를 수반하는 병의 치료
KR100659820B1 (ko) 2004-11-17 2006-12-19 삼성에스디아이 주식회사 리튬 이온 이차 전지
SG157418A1 (en) * 2004-12-01 2009-12-29 Univ Singapore Nogo a protein fragments as neuronal network- interacting peptides
EP1904091A4 (en) 2005-07-07 2009-12-23 Univ Yale COMPOSITIONS AND METHODS FOR SUPPRESSING THE INHIBITION OF AXON GROWTH
WO2007008547A2 (en) 2005-07-08 2007-01-18 Biogen Idec Ma Inc. Sp35 antibodies and uses thereof
US20070026463A1 (en) * 2005-07-28 2007-02-01 Wyeth Compositions and methods of mutant Nogo-66 domain proteins
RU2008123384A (ru) 2005-11-16 2009-12-27 Новартис АГ (CH) БИОМАРКЕРЫ ДЛЯ ЛЕЧЕНИЯ АНТИТЕЛОМ к Nogo-A ПРИ ПОВРЕЖДЕНИЯХ СПИННОГО МОЗГА
GB0525662D0 (en) 2005-12-16 2006-01-25 Glaxo Group Ltd Immunoglobulins
WO2007137303A2 (en) * 2006-05-24 2007-11-29 Myelin Repair Foundation, Inc. Permeability of blood-brain barrier
CN101015683B (zh) * 2007-01-18 2010-07-21 复旦大学 人rtn4b蛋白在制备创伤愈合药物中的应用
AU2008317724B2 (en) * 2007-11-02 2011-06-02 Novartis Ag Improved Nogo-A binding molecules and pharmaceutical use thereof
CN101874207A (zh) * 2007-11-22 2010-10-27 西福根有限公司 用于表征重组多克隆蛋白质的方法
NZ590605A (en) 2008-07-09 2012-11-30 Biogen Idec Inc Compositions comprising antibodies to lingo or fragments thereof
KR20120122869A (ko) * 2009-06-02 2012-11-07 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 신경변성 질환을 갖는 대상에서 항체에 의해 인식되는 소분자의 확인법
US8828390B2 (en) 2010-07-09 2014-09-09 Universitat Zurich Uses of NOGO-A inhibitors and related methods
RU2478646C1 (ru) * 2011-11-28 2013-04-10 Федеральное государственное бюджетное учреждение науки Институт молекулярной биологии им.В.А.Энгельгардта Российской академии наук (ИМБ РАН) Способ получения высокоаффинных поликлональных антител
MX2014013950A (es) 2012-05-14 2015-02-17 Biogen Idec Inc Antagonistas de proteina que interactua con el receptor nogo 2 que contiene repeticion rica en leucina y dominio de inmunoglobulina (lingo-2) para el tratamiento de afecciones que involucran neuronas motoras.
EP3030171B1 (en) 2013-08-08 2017-11-01 Global Bio Therapeutics, Inc. Injection device for minimally invasive procedures
KR101685109B1 (ko) * 2014-12-22 2016-12-09 경북대학교 산학협력단 근육 분화, 재생, 또는 질환 상태와 관련된 노고-에이의 용도
EP3242893A1 (en) 2015-01-08 2017-11-15 Biogen MA Inc. Lingo-1 antagonists and uses for treatment of demyelinating disorders
EP3250220B1 (en) * 2015-01-27 2020-03-11 Universität Zürich Agonists of the nogo-a s1pr pathway for the treatment of glioblastoma

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CA1173823A (en) 1980-08-26 1984-09-04 Leonard M. Hjelmeland Nondenaturing zwitterionic detergent for membrane biochemistry
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CA1341401C (en) 1984-03-23 2002-11-26 Adriano Fontana Immunosuppressant factor derived from human glioblastoma cells
EP0233838A3 (en) 1986-02-04 1990-01-31 Incyte Pharmaceuticals, Inc. Neurite-promoting factor and process for the manufacture thereof
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US5250414A (en) 1988-11-04 1993-10-05 Erziehungsdirektion Of The Canton Zurich Diagnostic methods using neurite growth regulatory factors
AU652537B2 (en) 1988-11-04 1994-09-01 Erziehungsdirektion Of The Canton Zurich Neurite growth regulatory factors
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US5858708A (en) * 1996-08-12 1999-01-12 Bandman; Olga Polynucleotides encoding two novel human neuroendocrine-specific proteins
CA2269755A1 (en) * 1996-10-25 1998-04-30 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
AU1929599A (en) * 1997-12-30 1999-07-19 Chiron Corporation Bone marrow secreted proteins and polynucleotides
US6607879B1 (en) * 1998-02-09 2003-08-19 Incyte Corporation Compositions for the detection of blood cell and immunological response gene expression
US20020072493A1 (en) * 1998-05-19 2002-06-13 Yeda Research And Development Co. Ltd. Activated T cells, nervous system-specific antigens and their uses
DK1098972T3 (da) * 1998-07-22 2011-01-03 Smithkline Beecham Ltd Protein med lighed med neuroendokrinspecifikt protein samt cDNA kodende derfor
WO2000011015A1 (en) * 1998-08-24 2000-03-02 Alphagene, Inc. Secreted proteins and polynucleotides encoding them
AU774367C (en) 1998-11-06 2005-04-21 University Of Zurich Nucleotide and protein sequences of nogo genes and methods based thereon
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Also Published As

Publication number Publication date
CA2350395C (en) 2014-07-08
US20090162367A1 (en) 2009-06-25
IL198027A (en) 2011-10-31
RU2304585C2 (ru) 2007-08-20
RU2004103555A (ru) 2005-07-20
AU774367B2 (en) 2004-06-24
IL142989A0 (en) 2002-04-21
JP2003531566A (ja) 2003-10-28
WO2000031235A2 (en) 2000-06-02
ES2529196T3 (es) 2015-02-17
JP2012213406A (ja) 2012-11-08
PL204293B1 (pl) 2009-12-31
IL142989A (en) 2010-12-30
RU2009103533A (ru) 2010-11-10
CN1354755A (zh) 2002-06-19
SK6222001A3 (en) 2001-12-03
CZ304224B6 (cs) 2014-01-15
US7781188B1 (en) 2010-08-24
US20050260616A1 (en) 2005-11-24
NO20012223L (no) 2001-07-02
CA2350395A1 (en) 2000-06-02
BR9915137A (pt) 2004-06-08
NZ511683A (en) 2004-06-25
SK287323B6 (sk) 2010-07-07
NO20012223D0 (no) 2001-05-04
EP1124846A4 (en) 2002-06-12
DE69941059D1 (de) 2009-08-13
EP2333064A1 (en) 2011-06-15
DK1124846T3 (da) 2009-10-26
CY1110679T1 (el) 2015-06-10
US20110086034A1 (en) 2011-04-14
KR20020003353A (ko) 2002-01-12
WO2000031235A3 (en) 2000-11-09
CN101684155A (zh) 2010-03-31
AU1469200A (en) 2000-06-13
EP1124846B1 (en) 2009-07-01
ZA200103714B (en) 2004-06-25
RU2432364C2 (ru) 2011-10-27
ATE435232T1 (de) 2009-07-15
MXPA01004598A (es) 2002-04-24
PL362990A1 (en) 2004-11-15
US7425334B2 (en) 2008-09-16
TR200700740T2 (tr) 2007-04-24
PT1124846E (pt) 2009-10-08
AU774367C (en) 2005-04-21
RU2358982C2 (ru) 2009-06-20
RU2001115705A (ru) 2004-03-10
HK1038027A1 (en) 2002-03-01
EP2093294A1 (en) 2009-08-26
KR100728405B1 (ko) 2007-06-13
EP2093294B1 (en) 2014-10-29
HUP0301829A3 (en) 2009-03-30
CN1721444A (zh) 2006-01-18
ES2329635T3 (es) 2009-11-27
CN1354755B (zh) 2010-06-02
EP1124846A2 (en) 2001-08-22
HUP0301829A2 (hu) 2003-08-28
CZ20011608A3 (cs) 2001-10-17

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