NO331616B1 - Anvendelse av ramipril for forebyggelse eller reduksjon av risikoen for en kardiovaskulaer hendelse i en pasient uten tegn pa venstreventrikulaer dysfunksjon eller hjertesvikt. - Google Patents
Anvendelse av ramipril for forebyggelse eller reduksjon av risikoen for en kardiovaskulaer hendelse i en pasient uten tegn pa venstreventrikulaer dysfunksjon eller hjertesvikt. Download PDFInfo
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- NO331616B1 NO331616B1 NO20020978A NO20020978A NO331616B1 NO 331616 B1 NO331616 B1 NO 331616B1 NO 20020978 A NO20020978 A NO 20020978A NO 20020978 A NO20020978 A NO 20020978A NO 331616 B1 NO331616 B1 NO 331616B1
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- Prior art keywords
- ramipril
- patients
- risk
- cholesterol
- agent
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Classifications
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- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
- A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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Landscapes
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- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Hospice & Palliative Care (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Electrotherapy Devices (AREA)
- Medicines Containing Plant Substances (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
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US15143699P | 1999-08-30 | 1999-08-30 | |
PCT/EP2000/008461 WO2001015674A2 (fr) | 1999-08-30 | 2000-08-30 | Utilisation d'inhibiteurs du systeme renine-angiotensine dans la prevention de manifestations cardio-vasculaires |
Publications (3)
Publication Number | Publication Date |
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NO20020978D0 NO20020978D0 (no) | 2002-02-27 |
NO20020978L NO20020978L (no) | 2002-04-18 |
NO331616B1 true NO331616B1 (no) | 2012-02-06 |
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NO20020978A NO331616B1 (no) | 1999-08-30 | 2002-02-27 | Anvendelse av ramipril for forebyggelse eller reduksjon av risikoen for en kardiovaskulaer hendelse i en pasient uten tegn pa venstreventrikulaer dysfunksjon eller hjertesvikt. |
Country Status (31)
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US (4) | US20040087645A1 (fr) |
EP (1) | EP1216038B1 (fr) |
JP (1) | JP4870888B2 (fr) |
KR (2) | KR20020040795A (fr) |
CN (1) | CN1268331C (fr) |
AT (1) | ATE303800T1 (fr) |
AU (3) | AU7649100A (fr) |
BG (2) | BG110003A (fr) |
BR (1) | BR0013704A (fr) |
CA (1) | CA2382549C (fr) |
CZ (1) | CZ300687B6 (fr) |
DE (1) | DE60022525T2 (fr) |
DK (1) | DK1216038T3 (fr) |
EE (1) | EE05670B1 (fr) |
ES (1) | ES2246894T3 (fr) |
HK (1) | HK1048267B (fr) |
HR (1) | HRP20020170A2 (fr) |
HU (1) | HUP0203326A3 (fr) |
IL (2) | IL148127A0 (fr) |
ME (1) | ME00429B (fr) |
MX (1) | MXPA02001694A (fr) |
NO (1) | NO331616B1 (fr) |
NZ (2) | NZ517468A (fr) |
PL (1) | PL353199A1 (fr) |
RS (1) | RS50377B (fr) |
RU (2) | RU2276997C2 (fr) |
SK (1) | SK2692002A3 (fr) |
TR (1) | TR200200515T2 (fr) |
UA (2) | UA77151C2 (fr) |
WO (1) | WO2001015674A2 (fr) |
ZA (1) | ZA200201470B (fr) |
Families Citing this family (55)
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DE69830069T3 (de) * | 1997-10-17 | 2012-02-09 | Ark Therapeutics Ltd. | Verwendung von hemmern des renin-angiotensin systems zur behandlung von hypoxie oder verringertem stoffwechsel |
CN101011390A (zh) * | 1999-01-26 | 2007-08-08 | 诺瓦提斯公司 | 血管紧张素ⅱ受体拮抗剂在治疗急性心肌梗塞中的应用 |
SE9903028D0 (sv) * | 1999-08-27 | 1999-08-27 | Astra Ab | New use |
WO2001015674A2 (fr) * | 1999-08-30 | 2001-03-08 | Aventis Pharma Deutschland Gmbh | Utilisation d'inhibiteurs du systeme renine-angiotensine dans la prevention de manifestations cardio-vasculaires |
GB2361185A (en) | 2000-04-10 | 2001-10-17 | Nicholas J Wald | Pharmaceutical formulation for the prevention of cardiovascular disease |
GB0020691D0 (en) * | 2000-08-22 | 2000-10-11 | Boehringer Ingelheim Pharma | Pharmaceutical combination |
US20060089389A1 (en) * | 2000-08-22 | 2006-04-27 | Malcolm Allison | Combination |
AR033390A1 (es) * | 2000-08-22 | 2003-12-17 | Novartis Ag | Una composicion farmaceutica que comprende un antagonista del receptor at1 y un potenciador de la secrecion de insulina, el uso de dicha composicion para la fabricacion de un medicamento y un kit de partes |
JP2004520268A (ja) * | 2000-08-22 | 2004-07-08 | ベーリンガー インゲルハイム ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト | アンギオテンシンii拮抗剤とアンギオテンシンi変換酵素阻害剤とを含有する医薬組成物 |
CA2420844A1 (fr) * | 2000-08-30 | 2003-02-28 | Sankyo Company, Limited | Compositions medicinales utilisees dans la prevention ou le traitement de l'insuffisance cardiaque |
US20030158090A1 (en) * | 2001-07-23 | 2003-08-21 | Ulrik Pedersen-Bjergaard | Renin-angiotensin system in diabetes mellitus |
GB0119460D0 (en) * | 2001-08-09 | 2001-10-03 | Ark Therapeutics Ltd | The use of inhibitors of the renin-angiotensin system |
US6576256B2 (en) | 2001-08-28 | 2003-06-10 | The Brigham And Women's Hospital, Inc. | Treatment of patients at elevated cardiovascular risk with a combination of a cholesterol-lowering agent, an inhibitor of the renin-angiotensin system, and aspirin |
US6669955B2 (en) * | 2001-08-28 | 2003-12-30 | Longwood Pharmaceutical Research, Inc. | Combination dosage form containing individual dosage units of a cholesterol-lowering agent, an inhibitor of the renin-angiotensin system, and aspirin |
MXPA04003022A (es) * | 2001-10-17 | 2004-07-05 | Aventis Pharma Gmbh | Metodo para reducir diabetes tipo 2 en pacientes de alto riesgo. |
CA2467095A1 (fr) * | 2001-11-23 | 2003-05-30 | Solvay Pharmaceuticals Gmbh | Traitement de l'hypertonie durant la phase aigue d'apoplexie cerebrale |
DE10229180A1 (de) | 2002-06-28 | 2004-01-29 | Aventis Pharma Deutschland Gmbh | Verwendung von Vasopeptidase-Inhibitoren bei der Behandlung von metabolischen Erkrankungen, Nephropathie und mit AGE assoziierten Erkrankungen |
EP1382334A1 (fr) * | 2002-07-11 | 2004-01-21 | Université de Picardie Jules Verne | Utilisation d'un agent bloquant du récepteur AT1 de l'angiotensine II, seul ou combiné avec un thiazide ou l'angiotensine II dans le traitement des accidents vasculaires cérébraux |
US6936639B2 (en) * | 2002-08-21 | 2005-08-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Nitroxyl progenitors in the treatment of heart failure |
AU2003274004A1 (en) * | 2002-10-16 | 2004-05-04 | Recordati Ireland Limited | Lisinopril/lercanidipine combination therapy |
DE10301371A1 (de) * | 2003-01-16 | 2004-08-05 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pharmazeutische Kombination zur Prophylaxe oder Therapie von kardiovaskulären, kardiopulmonalen, pulmonalen oder renalen Krankheiten |
AU2004204353A1 (en) * | 2003-01-16 | 2004-07-29 | Boehringer Ingelheim International Gmbh | Pharmaceutical combination for the prophylaxis or treatment of cardiovascular, cardiopulmonary, pulmonary or renal diseases |
JP3874419B2 (ja) * | 2003-01-31 | 2007-01-31 | 三共株式会社 | 動脈硬化及び高血圧症の予防及び治療のための医薬 |
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JP2009513543A (ja) * | 2003-07-16 | 2009-04-02 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | クロルタリドンの組み合わせ |
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WO2005030202A1 (fr) * | 2003-09-26 | 2005-04-07 | Novartis Ag | Utilisation des antagonistes du recepteur de l'angiotensine ii pour le traitement de troubles cerebrovasculaires |
GB0322552D0 (en) | 2003-09-26 | 2003-10-29 | Astrazeneca Uk Ltd | Therapeutic treatment |
TW200605867A (en) * | 2004-03-17 | 2006-02-16 | Novartis Ag | Use of organic compounds |
EP1776095A1 (fr) * | 2004-06-23 | 2007-04-25 | Solvay Pharmaceuticals GmbH | Compositions pharmaceutiques comprenant des inhibiteurs de l'epn, inhibiteurs du systeme de production de l'endotheline endogene et antagonistes du recepteur at1 |
JP4675586B2 (ja) * | 2004-06-23 | 2011-04-27 | 壽製薬株式会社 | 高血圧症及び血清高尿酸血症の重複発症の治療のための薬剤 |
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JP2008528456A (ja) * | 2005-01-26 | 2008-07-31 | レツク・フアーマシユーテイカルズ・デー・デー | 親油性結晶性物質としてカンデサルタンシレキセチルを含む新規な医薬組成物 |
EP1898951B1 (fr) * | 2005-06-27 | 2013-02-27 | Daiichi Sankyo Company, Limited | Préparation pharmaceutique contenant un antagoniste du récepteur de l'angiotensine ii et un bloqueur du canal calcique |
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WO2007053406A1 (fr) * | 2005-10-28 | 2007-05-10 | Novartis Ag | Combinaison de composes organiques hypotenseurs et hypocholesterolemiant |
US20070116756A1 (en) * | 2005-11-23 | 2007-05-24 | Dr. Reddy's Laboratories Limited | Stable pharmaceutical compositions |
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TWI399223B (zh) * | 2006-09-15 | 2013-06-21 | Daiichi Sankyo Co Ltd | 奧美沙坦酯及氨氯地平之固體劑型 |
JP5377317B2 (ja) | 2006-10-30 | 2013-12-25 | ハナル バイオファーマ カンパニー リミテッド | 放出性が制御されたアンジオテンシン−II−受容体遮断剤とHMG−CoA還元酵素阻害剤の複合組成物 |
US8394845B2 (en) | 2006-10-30 | 2013-03-12 | Hanall Biopharma Co., Ltd. | Method of using combination preparation comprising angiotensin-II-receptor blocker and HMG-CoA reductase inhibitor |
WO2008054121A1 (fr) * | 2006-10-30 | 2008-05-08 | Hanall Pharmaceutical Company. Ltd | Composition pharmaceutique à libération contrôlée contenant des thiazides et des bloqueurs des récepteurs de l'angiotensine ii |
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GB0624090D0 (en) * | 2006-12-01 | 2007-01-10 | Selamine Ltd | Ramipril amine salts |
GB0624084D0 (en) * | 2006-12-01 | 2007-01-10 | Selamine Ltd | Ramipril amino acid salts |
WO2011063339A1 (fr) * | 2009-11-23 | 2011-05-26 | Cardioxyl Pharmaceuticals, Inc. | Donneurs de nitroxyle destinés au traitement de l'hypertension pulmonaire |
WO2011071947A2 (fr) * | 2009-12-07 | 2011-06-16 | Johns Hopkins University | Dérivés d'hydroxylamine bis-acylée |
CA2782110A1 (fr) * | 2009-12-07 | 2011-06-16 | Johns Hopkins University | Derives de n-acyloxysulfonamide et de n-hydroxy-n-acylsulfonamide |
SI2538924T1 (sl) | 2010-02-24 | 2014-09-30 | Sanofi-Aventis Deutschland Gmbh | Trdne farmacevtske formulacije ramiprila in amlodipin bezilata in njihova priprava |
US20130345182A1 (en) * | 2010-12-21 | 2013-12-26 | Silanes Laboratories | Stable composition comprising cholesterol-lowering agents, antihypertensive agents and antiplatlet agents |
BR102012020648A2 (pt) * | 2012-08-17 | 2014-12-09 | Hypermarcas S A | Preparação farmacêutica oral sólida para a prevenção de doença cardio e cerebrovasculares e comprimido |
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2000
- 2000-08-30 WO PCT/EP2000/008461 patent/WO2001015674A2/fr active Application Filing
- 2000-08-30 KR KR1020027002626A patent/KR20020040795A/ko not_active Application Discontinuation
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- 2000-08-30 ES ES00965906T patent/ES2246894T3/es not_active Expired - Lifetime
- 2000-08-30 AU AU76491/00A patent/AU7649100A/en not_active Abandoned
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