NO330508B1 - Blanding bestaende av syntetisk fosfodiester-nukleotidsekvens og anvendelse derav. - Google Patents
Blanding bestaende av syntetisk fosfodiester-nukleotidsekvens og anvendelse derav. Download PDFInfo
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- NO330508B1 NO330508B1 NO20022820A NO20022820A NO330508B1 NO 330508 B1 NO330508 B1 NO 330508B1 NO 20022820 A NO20022820 A NO 20022820A NO 20022820 A NO20022820 A NO 20022820A NO 330508 B1 NO330508 B1 NO 330508B1
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| PCT/CA2000/001467 WO2001044465A2 (en) | 1999-12-13 | 2000-12-12 | Therapeutically useful synthetic oligonucleotides |
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| PT (1) | PT1238070E (da) |
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| US20030032610A1 (en) | 1996-06-03 | 2003-02-13 | Gilchrest Barbara A. | Method to inhibit cell growth using oligonucleotides |
| PT1181304E (pt) | 1999-04-08 | 2008-01-23 | Antisoma Res Ltd | Actividade antiproliferativa de oligonucleótidos ricos em g e método de utilização dos mesmos para ligação a nucleolina |
| US7960540B2 (en) | 1999-04-08 | 2011-06-14 | Advanced Cancer Therapeutics, Llc | Antiproliferative activity of G-rich oligonucleotides and method of using same to bind to nucleolin |
| US8114850B2 (en) | 1999-04-08 | 2012-02-14 | Advanced Cancer Therapeutics, Llc | Antiproliferative activity of G-rich oligonucleotides and method of using same to bind to nucleolin |
| US6949520B1 (en) * | 1999-09-27 | 2005-09-27 | Coley Pharmaceutical Group, Inc. | Methods related to immunostimulatory nucleic acid-induced interferon |
| CN100445380C (zh) * | 1999-12-13 | 2008-12-24 | 拜昂尼科生命科学有限公司 | 治疗用合成寡核苷酸 |
| AU6886301A (en) | 2000-08-29 | 2002-03-13 | Bioniche Life Sciences Inc | Modulation of fas and fasl expression |
| ES2307568T3 (es) * | 2000-12-08 | 2008-12-01 | Coley Pharmaceutical Gmbh | Acidos nucleicos de tipo cpg y metodos de uso de los mismos. |
| US7087586B2 (en) * | 2001-04-24 | 2006-08-08 | Bioniche Life Sciences, Inc. | Oligonucleotide compositions and their use to induce differentiation of cells |
| EP1417307B1 (en) * | 2001-08-17 | 2009-04-15 | Bioniche Life Sciences Inc. | Oligonucleotide compositions and their use to induce apoptosis |
| EP1432450B1 (en) * | 2001-10-03 | 2005-12-28 | Bioniche Life Sciences Inc. | Therapeutically useful triethyleneglycol cholesteryl oligonucleotides |
| AU2003219383B2 (en) * | 2002-04-22 | 2010-08-26 | Bioniche Life Sciences Inc. | Oligonucleotide compositions and their use for the modulation of immune responses |
| WO2004087203A2 (en) * | 2003-04-02 | 2004-10-14 | Coley Pharmaceutical Group, Ltd. | Immunostimulatory nucleic acid oil-in-water formulations for topical application |
| US7569554B2 (en) * | 2003-05-16 | 2009-08-04 | Idera Pharmaceuticals, Inc. | Synergistic treatment of cancer using immunomers in conjunction with therapeutic agents |
| CA2598992A1 (en) * | 2005-02-24 | 2006-08-31 | Coley Pharmaceutical Group, Inc. | Immunostimulatory oligonucleotides |
| EP1863538A4 (en) * | 2005-03-09 | 2009-01-14 | Baylor College Medicine | DIRECT INVERSION OF CD4 + T CELL LYMPHOCYTE INHIBITOR FUNCTION VIA TOLL-TYPE 8 RECEIVER SIGNALING |
| GB2443591B (en) * | 2005-09-07 | 2010-04-28 | Secr Defence | Adjuvanted vaccine |
| ES2658626T3 (es) * | 2009-02-12 | 2018-03-12 | Curna, Inc. | Tratamiento de enfermedades relacionadas con el factor neurotrófico derivado de células gliales (GDNF) por inhibición de transcrito antisentido natural a GDNF |
| GB0906234D0 (en) | 2009-04-14 | 2009-05-20 | Secr Defence | Vaccine |
| KR100998365B1 (ko) | 2009-06-29 | 2010-12-06 | 압타바이오 주식회사 | 치료 효능이 있는 변형핵산 및 구아노신을 함유하는 올리고뉴클레오티드 변형체 |
| TW201102073A (en) * | 2009-07-15 | 2011-01-16 | Enzon Pharmaceuticals Inc | RNA antagonists targeting GLI2 for the treatment of leukemia |
| WO2013129603A1 (ja) * | 2012-02-28 | 2013-09-06 | 国立大学法人東京農工大学 | Tdp-43細胞内存在量関連疾患の認定方法 |
| EP4000597A1 (en) * | 2020-11-17 | 2022-05-25 | The Boots Company plc | Tetrapeptide and compositions comprising tetrapeptides |
| CA3242118A1 (en) * | 2021-12-22 | 2023-06-29 | Alfica Sehgal | Modulation of gene transcription using antisense oligonucleotides targeting regulatory rnas |
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| AU2003219383B2 (en) * | 2002-04-22 | 2010-08-26 | Bioniche Life Sciences Inc. | Oligonucleotide compositions and their use for the modulation of immune responses |
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