ATE383172T1 - Oligonukleotide welche spezifisch retrovirale nukleokapsid-proteine binden - Google Patents
Oligonukleotide welche spezifisch retrovirale nukleokapsid-proteine bindenInfo
- Publication number
- ATE383172T1 ATE383172T1 AT97926743T AT97926743T ATE383172T1 AT E383172 T1 ATE383172 T1 AT E383172T1 AT 97926743 T AT97926743 T AT 97926743T AT 97926743 T AT97926743 T AT 97926743T AT E383172 T1 ATE383172 T1 AT E383172T1
- Authority
- AT
- Austria
- Prior art keywords
- oligonucleotides
- nucleocapsid proteins
- specifically bind
- retroviral nucleocapsid
- retroviral
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
- G01N33/56988—HIV or HTLV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/549—Sugars, nucleosides, nucleotides or nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/702—Specific hybridization probes for retroviruses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6811—Selection methods for production or design of target specific oligonucleotides or binding molecules
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/15—Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, feline leukaemia virus, human T-cell leukaemia-lymphoma virus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Food Science & Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biophysics (AREA)
- AIDS & HIV (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1712896P | 1996-05-20 | 1996-05-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE383172T1 true ATE383172T1 (de) | 2008-01-15 |
Family
ID=21780880
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT97926743T ATE383172T1 (de) | 1996-05-20 | 1997-05-19 | Oligonukleotide welche spezifisch retrovirale nukleokapsid-proteine binden |
Country Status (7)
Country | Link |
---|---|
US (1) | US6316190B1 (de) |
EP (1) | EP1011729B1 (de) |
AT (1) | ATE383172T1 (de) |
AU (1) | AU737926B2 (de) |
CA (1) | CA2255822A1 (de) |
DE (1) | DE69738454D1 (de) |
WO (1) | WO1997044064A2 (de) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6221600B1 (en) * | 1999-10-08 | 2001-04-24 | Board Of Regents, The University Of Texas System | Combinatorial oligonucleotide PCR: a method for rapid, global expression analysis |
EP1238070B1 (de) * | 1999-12-13 | 2007-08-15 | Bioniche Life Sciences Inc. | Synthetische oligonukleotide die therapeutisch nützlich sind |
US20020091095A1 (en) * | 1999-12-13 | 2002-07-11 | Phillips Nigel C. | Modulation of Fas and FasL expression |
US7115370B2 (en) | 2002-06-05 | 2006-10-03 | Capital Genomix, Inc. | Combinatorial oligonucleotide PCR |
US20050196382A1 (en) * | 2002-09-13 | 2005-09-08 | Replicor, Inc. | Antiviral oligonucleotides targeting viral families |
KR101360955B1 (ko) * | 2002-09-13 | 2014-02-10 | 레플리코르 인코포레이티드 | 비서열 상보적 항바이러스 올리고뉴클레오티드 |
US7572828B2 (en) | 2002-10-08 | 2009-08-11 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Identification of anti-HIV compounds inhibiting virus assembly and binding of nucleocapsid protein to nucleic acid |
EP1493810A1 (de) * | 2003-06-30 | 2005-01-05 | Gentium S.p.A. | Auf DNA-basierte Aptamere für Cathepsin G |
SI2158316T1 (sl) | 2007-05-11 | 2015-08-31 | Adynxx Inc. | Genska ekspresija in bolečina |
JP2012528882A (ja) * | 2009-06-03 | 2012-11-15 | ダイセルナ ファーマシューティカルズ, インコーポレイテッド | ペプチドダイサー基質剤およびその特異的な遺伝子発現阻害のための方法 |
ES2724851T3 (es) | 2012-05-10 | 2019-09-16 | Adynxx Inc | Formulaciones para el suministro de principios activos |
US10208358B2 (en) * | 2014-04-14 | 2019-02-19 | Indiana University Reasearch and Technology Corporation | Generalizable assay for virus capsid assembly |
EP3626822A1 (de) | 2014-08-15 | 2020-03-25 | Adynxx, Inc. | Oligonukleotidköder zur behandlung von schmerz |
EP3235828A1 (de) * | 2016-04-21 | 2017-10-25 | Genethon | Stabile pseudotypisierte lentivirale teilchen und verwendungen davon |
KR102617592B1 (ko) * | 2022-05-23 | 2023-12-29 | 주식회사 백스다임 | 바이러스 뉴클레오캡시드를 이용한 오량체형 독소 단백질 기반 목적 단백질 융합 오량체 제조 플랫폼 |
WO2023229328A1 (ko) * | 2022-05-23 | 2023-11-30 | 주식회사 백스다임 | 바이러스 뉴클레오캡시드를 이용한 목적 단백질 발현 플랫폼 |
KR102677201B1 (ko) * | 2022-05-23 | 2024-06-25 | 주식회사 백스다임 | 바이러스 뉴클레오캡시드를 이용한 결정성 단백질 기반 목적 단백질 융합 자가 조립 나노 입자 제조 플랫폼 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK0500791T3 (da) * | 1989-10-31 | 1998-04-06 | Us Health | Udformning og konstruktion af ikke-infektiøse human retrovirale mutanter, der mangler genomisk DNA |
US5294536A (en) * | 1992-04-23 | 1994-03-15 | Pb Diagnostic Systems, Inc. | Conjugates |
DE4427219A1 (de) * | 1994-08-01 | 1996-02-08 | Max Planck Gesellschaft | Nukleinsäure zur Initiation der Aktivität von RNase H bzw. reverser Transkriptase |
US6001555A (en) | 1994-09-23 | 1999-12-14 | The United States Of America As Represented By The Department Of Health And Human Services | Method for identifying and using compounds that inactivate HIV-1 and other retroviruses by attacking highly conserved zinc fingers in the viral nucleocapsid protein |
-
1997
- 1997-05-19 DE DE69738454T patent/DE69738454D1/de not_active Expired - Lifetime
- 1997-05-19 EP EP97926743A patent/EP1011729B1/de not_active Expired - Lifetime
- 1997-05-19 US US09/180,903 patent/US6316190B1/en not_active Expired - Lifetime
- 1997-05-19 AT AT97926743T patent/ATE383172T1/de not_active IP Right Cessation
- 1997-05-19 WO PCT/US1997/008936 patent/WO1997044064A2/en active IP Right Grant
- 1997-05-19 CA CA002255822A patent/CA2255822A1/en not_active Abandoned
- 1997-05-19 AU AU31438/97A patent/AU737926B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
US6316190B1 (en) | 2001-11-13 |
AU3143897A (en) | 1997-12-09 |
WO1997044064A3 (en) | 1998-05-14 |
EP1011729A2 (de) | 2000-06-28 |
CA2255822A1 (en) | 1997-11-27 |
AU737926B2 (en) | 2001-09-06 |
EP1011729B1 (de) | 2008-01-09 |
WO1997044064A2 (en) | 1997-11-27 |
DE69738454D1 (de) | 2008-02-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE383172T1 (de) | Oligonukleotide welche spezifisch retrovirale nukleokapsid-proteine binden | |
CY1112101T1 (el) | Νευροτροφικοι παραγοντες | |
DE69714654D1 (de) | Verwendung von einem Metalloporphyrinkonjugat für den Nachweis biologischer Verbindungen | |
BR9811039A (pt) | Citocina de mamìferos: interleucina-b30 e reagentes relacionados | |
ATE412432T1 (de) | Internalisierende erbb2 antikörper | |
DE69835143D1 (de) | Selektion von proteinen mittels rns-protein fusionen | |
DE60041452D1 (de) | CpG REZEPTOR (CpG-R) UND DARAUF BEZOGENE METHODEN | |
DK0593618T3 (da) | Screeningsassay til påvisning af DNA-bindende molekyler | |
DE69832293D1 (de) | Zubereitungen zur abgabe von negativ geladenen molekülen | |
ATE365916T1 (de) | Biodetektoren für spezifische liganden | |
CA2251842A1 (en) | Small molecule mimetics of erythropoietin | |
DE69942459D1 (de) | Isolierte nukleinsäuremoleküle die t-zellen induzierbare faktoren kodieren (tif), kodierte proteine und ihre anwendung | |
DK1290444T3 (da) | Toxicitetstypisering under anvendelse af lever-stamceller | |
BR9812783A (pt) | "sistemas de detecção para o registro de interações e as relações funcionais de proteìnas" | |
CY1108288T1 (el) | Αντισωματα για το αντιγονο κυτταρων langerhans θηλαστικων και χρησεις τους | |
WO1999030165A3 (en) | Processes for identifying a solvent condition suitable for determining a biophysical property of a protein | |
NO20006109L (no) | Analytisk metode som benytter multippel virusmerking | |
DE59813433D1 (de) | Aufreinigung von substanzen aus einer biologischen probe | |
DE69913325D1 (de) | Nephrin gen und protein | |
BR9710919A (pt) | Proteina purificada sr-p70 | |
CY1106349T1 (el) | Συστηματα ανιχνευσης ανοσοπροσδιορισμου ιικου αντιγονου ηπατιτιδας c | |
DK0923644T3 (da) | G-koblet receptor, der udviser selektiv selektivitet for ATP | |
DE60121456D1 (de) | Farbstoff-markiertes peptid und dessen verwendung zur diagnostik | |
EA199800843A1 (ru) | Компьютерный способ создания химических структур, имеющих общие функциональные характеристики | |
CY1106355T1 (el) | Πρωτεϊνη συνδεομενη με αποπτινη |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |