NO330495B1 - Kontrollmetode og apparat for kontroll av magnetiske partikler ved hjelp av en provefordeler - Google Patents
Kontrollmetode og apparat for kontroll av magnetiske partikler ved hjelp av en provefordeler Download PDFInfo
- Publication number
- NO330495B1 NO330495B1 NO19990558A NO990558A NO330495B1 NO 330495 B1 NO330495 B1 NO 330495B1 NO 19990558 A NO19990558 A NO 19990558A NO 990558 A NO990558 A NO 990558A NO 330495 B1 NO330495 B1 NO 330495B1
- Authority
- NO
- Norway
- Prior art keywords
- magnetic particles
- liquid
- processing
- sample
- pipette
- Prior art date
Links
- 239000006249 magnetic particle Substances 0.000 title claims description 260
- 238000000034 method Methods 0.000 title claims description 209
- 239000007788 liquid Substances 0.000 claims description 379
- 238000012545 processing Methods 0.000 claims description 228
- 230000008569 process Effects 0.000 claims description 93
- 239000003153 chemical reaction reagent Substances 0.000 claims description 92
- 238000009826 distribution Methods 0.000 claims description 84
- 238000000926 separation method Methods 0.000 claims description 79
- 238000006243 chemical reaction Methods 0.000 claims description 78
- 230000001276 controlling effect Effects 0.000 claims description 69
- 238000004140 cleaning Methods 0.000 claims description 66
- 238000011534 incubation Methods 0.000 claims description 55
- 238000003756 stirring Methods 0.000 claims description 54
- 239000000126 substance Substances 0.000 claims description 31
- 239000013076 target substance Substances 0.000 claims description 26
- 239000000463 material Substances 0.000 claims description 25
- 239000012530 fluid Substances 0.000 claims description 24
- 230000003287 optical effect Effects 0.000 claims description 24
- 239000000203 mixture Substances 0.000 claims description 21
- 230000000717 retained effect Effects 0.000 claims description 21
- 238000005259 measurement Methods 0.000 claims description 19
- 238000000746 purification Methods 0.000 claims description 18
- 238000004458 analytical method Methods 0.000 claims description 15
- 238000007781 pre-processing Methods 0.000 claims description 11
- 238000013019 agitation Methods 0.000 claims description 9
- 230000000694 effects Effects 0.000 claims description 8
- 238000000605 extraction Methods 0.000 claims description 7
- 230000001105 regulatory effect Effects 0.000 claims description 5
- 238000003860 storage Methods 0.000 claims description 5
- 238000001816 cooling Methods 0.000 claims description 4
- 238000011161 development Methods 0.000 claims description 4
- 230000005855 radiation Effects 0.000 claims description 4
- 238000010894 electron beam technology Methods 0.000 claims description 2
- 239000010409 thin film Substances 0.000 claims description 2
- 239000002245 particle Substances 0.000 description 18
- 239000003550 marker Substances 0.000 description 16
- 230000007246 mechanism Effects 0.000 description 15
- 238000010276 construction Methods 0.000 description 12
- 239000000758 substrate Substances 0.000 description 10
- 238000010586 diagram Methods 0.000 description 9
- 238000004020 luminiscence type Methods 0.000 description 9
- 238000005086 pumping Methods 0.000 description 8
- 238000012360 testing method Methods 0.000 description 8
- 238000012546 transfer Methods 0.000 description 7
- 238000013461 design Methods 0.000 description 6
- 238000010438 heat treatment Methods 0.000 description 6
- 238000003018 immunoassay Methods 0.000 description 5
- 230000014759 maintenance of location Effects 0.000 description 5
- 238000002156 mixing Methods 0.000 description 5
- 102000004190 Enzymes Human genes 0.000 description 4
- 108090000790 Enzymes Proteins 0.000 description 4
- 238000004891 communication Methods 0.000 description 4
- 238000011049 filling Methods 0.000 description 4
- 230000006870 function Effects 0.000 description 4
- 230000001900 immune effect Effects 0.000 description 4
- 230000001976 improved effect Effects 0.000 description 4
- 238000007689 inspection Methods 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- 239000013049 sediment Substances 0.000 description 4
- 230000005540 biological transmission Effects 0.000 description 3
- 230000000984 immunochemical effect Effects 0.000 description 3
- 238000011835 investigation Methods 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 238000011109 contamination Methods 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 230000004907 flux Effects 0.000 description 2
- 238000002796 luminescence method Methods 0.000 description 2
- 239000008188 pellet Substances 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- -1 polypropylene Polymers 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 230000035945 sensitivity Effects 0.000 description 2
- 239000013589 supplement Substances 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 239000012780 transparent material Substances 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 108020004414 DNA Proteins 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 230000003321 amplification Effects 0.000 description 1
- 239000000427 antigen Substances 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 238000005056 compaction Methods 0.000 description 1
- 238000009833 condensation Methods 0.000 description 1
- 230000005494 condensation Effects 0.000 description 1
- 238000007405 data analysis Methods 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 230000001934 delay Effects 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 238000007667 floating Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000009396 hybridization Methods 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 239000004973 liquid crystal related substance Substances 0.000 description 1
- 230000004807 localization Effects 0.000 description 1
- 238000003754 machining Methods 0.000 description 1
- 239000000696 magnetic material Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000691 measurement method Methods 0.000 description 1
- 239000011859 microparticle Substances 0.000 description 1
- 238000011328 necessary treatment Methods 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 238000011017 operating method Methods 0.000 description 1
- 238000005192 partition Methods 0.000 description 1
- 239000013612 plasmid Substances 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000003908 quality control method Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 239000012258 stirred mixture Substances 0.000 description 1
- 239000002887 superconductor Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/28—Magnetic plugs and dipsticks
- B03C1/288—Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C2201/00—Details of magnetic or electrostatic separation
- B03C2201/26—Details of magnetic or electrostatic separation for use in medical or biological applications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/113332—Automated chemical analysis with conveyance of sample along a test line in a container or rack
- Y10T436/114998—Automated chemical analysis with conveyance of sample along a test line in a container or rack with treatment or replacement of aspirator element [e.g., cleaning, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/119163—Automated chemical analysis with aspirator of claimed structure
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25625—Dilution
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Landscapes
- Automatic Analysis And Handling Materials Therefor (AREA)
- Sampling And Sample Adjustment (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO19990558A NO330495B1 (no) | 1996-05-20 | 1999-02-05 | Kontrollmetode og apparat for kontroll av magnetiske partikler ved hjelp av en provefordeler |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/JP1996/001333 WO1997044671A1 (fr) | 1996-05-20 | 1996-05-20 | Procede et appareil pour commander des particules magnetiques a l'aide d'une machine de pipettage |
| NO19990558A NO330495B1 (no) | 1996-05-20 | 1999-02-05 | Kontrollmetode og apparat for kontroll av magnetiske partikler ved hjelp av en provefordeler |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO990558D0 NO990558D0 (no) | 1999-02-05 |
| NO990558L NO990558L (no) | 1999-02-05 |
| NO330495B1 true NO330495B1 (no) | 2011-05-02 |
Family
ID=14153304
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19990558A NO330495B1 (no) | 1996-05-20 | 1999-02-05 | Kontrollmetode og apparat for kontroll av magnetiske partikler ved hjelp av en provefordeler |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6509193B1 (Direct) |
| EP (1) | EP0965842B1 (Direct) |
| JP (1) | JP3682302B2 (Direct) |
| AU (1) | AU738336B2 (Direct) |
| CA (1) | CA2255658C (Direct) |
| DE (1) | DE69638151D1 (Direct) |
| NO (1) | NO330495B1 (Direct) |
| WO (1) | WO1997044671A1 (Direct) |
Families Citing this family (134)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6048734A (en) | 1995-09-15 | 2000-04-11 | The Regents Of The University Of Michigan | Thermal microvalves in a fluid flow method |
| US6660228B1 (en) * | 1998-03-02 | 2003-12-09 | Cepheid | Apparatus for performing heat-exchanging, chemical reactions |
| DE69939622D1 (de) * | 1998-03-19 | 2008-11-06 | Prec System Science Co Ltd | Apparat zur integration von magnetteilchen - verarbeitung und steuerungsverfahren |
| DE19823719B4 (de) | 1998-05-27 | 2011-12-15 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Verfahren zum Aufkonzentrieren von Substanzen |
| ATE320443T1 (de) | 1999-07-15 | 2006-04-15 | Qiagen Gmbh | Verfahren zur trennung von teilchenförmigen substraten aus einer lösung indem man den teilchenverlust minimiert |
| JP3647023B2 (ja) * | 2000-04-13 | 2005-05-11 | アロカ株式会社 | 分注装置及び方法 |
| EP1306675A4 (en) * | 2000-06-30 | 2010-07-28 | Hitachi Ltd | LIQUID DISPENSING METHOD AND DEVICE |
| US6692700B2 (en) | 2001-02-14 | 2004-02-17 | Handylab, Inc. | Heat-reduction methods and systems related to microfluidic devices |
| US6852287B2 (en) | 2001-09-12 | 2005-02-08 | Handylab, Inc. | Microfluidic devices having a reduced number of input and output connections |
| US7010391B2 (en) | 2001-03-28 | 2006-03-07 | Handylab, Inc. | Methods and systems for control of microfluidic devices |
| US7829025B2 (en) | 2001-03-28 | 2010-11-09 | Venture Lending & Leasing Iv, Inc. | Systems and methods for thermal actuation of microfluidic devices |
| US7323140B2 (en) * | 2001-03-28 | 2008-01-29 | Handylab, Inc. | Moving microdroplets in a microfluidic device |
| US8895311B1 (en) | 2001-03-28 | 2014-11-25 | Handylab, Inc. | Methods and systems for control of general purpose microfluidic devices |
| US20030113233A1 (en) * | 2001-10-26 | 2003-06-19 | Elizabeth Nanthakumar | Resin dispensing device |
| US7514270B2 (en) * | 2002-04-12 | 2009-04-07 | Instrumentation Laboratory Company | Immunoassay probe |
| NO20023599D0 (no) * | 2002-07-29 | 2002-07-29 | Andrew T Campbell | Fremgangsmåte og anordning for manipulering av magnetiske partikler, spesielt for blanding, separasjon, oppsamling ogvasking |
| JP4254437B2 (ja) * | 2002-10-15 | 2009-04-15 | セイコーエプソン株式会社 | 液状体の充填方法、液状体の充填装置、及び吐出装置 |
| ES2461242T3 (es) | 2002-11-07 | 2014-05-19 | Mitsubishi Chemical Medience Corporation | Material magnético para recoger partículas magnéticas y utilización del mismo |
| US7648678B2 (en) | 2002-12-20 | 2010-01-19 | Dako Denmark A/S | Method and system for pretreatment of tissue slides |
| US20040157219A1 (en) * | 2003-02-06 | 2004-08-12 | Jianrong Lou | Chemical treatment of biological samples for nucleic acid extraction and kits therefor |
| JP4268968B2 (ja) | 2003-04-15 | 2009-05-27 | ユニバーサル・バイオ・リサーチ株式会社 | 分注用シリンダ、大容量分注装置および大容量分注装置の使用方法 |
| US8409528B2 (en) * | 2003-06-19 | 2013-04-02 | Abbott Laboratories | Apparatus and method for handling fluids for analysis |
| EP1650570B1 (en) * | 2003-07-17 | 2021-05-26 | LSI Medience Corporation | Apparatus for use in measuring a component contained in a sample comprising a measuring device and a cartridge |
| EP3718635A1 (en) | 2003-07-31 | 2020-10-07 | Handylab, Inc. | Processing particle-containing samples |
| JP2005069830A (ja) * | 2003-08-22 | 2005-03-17 | Sysmex Corp | 分注チップとそれを用いた分析装置 |
| US7396512B2 (en) * | 2003-11-04 | 2008-07-08 | Drummond Scientific Company | Automatic precision non-contact open-loop fluid dispensing |
| US8852862B2 (en) | 2004-05-03 | 2014-10-07 | Handylab, Inc. | Method for processing polynucleotide-containing samples |
| CA2994321C (en) * | 2004-05-03 | 2023-08-08 | Handylab, Inc. | A microfluidic device and methods for processing polynucleotide-containing samples |
| US8211386B2 (en) * | 2004-06-08 | 2012-07-03 | Biokit, S.A. | Tapered cuvette and method of collecting magnetic particles |
| AU2005271687A1 (en) * | 2004-08-03 | 2006-02-16 | Becton, Dickinson And Company | Use of magnetic material to fractionate samples |
| JP5053089B2 (ja) * | 2004-08-03 | 2012-10-17 | ベクトン・ディキンソン・アンド・カンパニー | 化合物の直接単離および多成分サンプルの分別のための磁性材料の使用 |
| WO2006062235A1 (ja) | 2004-12-10 | 2006-06-15 | Universal Bio Research Co., Ltd. | 生体物質固定担体封入チップ、生体物質固定担体処理装置およびその処理方法 |
| TWI416107B (zh) | 2004-12-10 | 2013-11-21 | Universal Bio Research Co Ltd | 封入生物材料固定用區域之滴尖、生物材料固定用區域處理裝置及其方法 |
| GB2425498A (en) * | 2005-04-25 | 2006-11-01 | Dynal Biotech Asa | A magnetic separation device |
| EP1882951B1 (en) * | 2005-05-19 | 2017-09-27 | Universal Bio Research Co., Ltd. | Method of detecting dispensed quantity, and liquid suction monitoring dispensing apparatus |
| US9260744B2 (en) | 2005-09-05 | 2016-02-16 | Universal Bio Research Co., Ltd. | Various-substance holder, various-substance holder treating apparatus, and various-substance holder treating method |
| FR2890596B1 (fr) * | 2005-09-13 | 2007-10-26 | Imaje Sa Sa | Dispositif de charge et deflexion de gouttes pour impression a jet d'encre |
| US20070184547A1 (en) * | 2005-10-11 | 2007-08-09 | Kalyan Handique | Polynucleotide sample preparation device |
| US20070136099A1 (en) * | 2005-12-13 | 2007-06-14 | Gordon Neligh | Distributed medicine system |
| TWI415770B (zh) | 2006-01-13 | 2013-11-21 | Universal Bio Research Co Ltd | 變形式分注管、變形式分注裝置及變形式分注處理方法 |
| US8883490B2 (en) * | 2006-03-24 | 2014-11-11 | Handylab, Inc. | Fluorescence detector for microfluidic diagnostic system |
| US11806718B2 (en) | 2006-03-24 | 2023-11-07 | Handylab, Inc. | Fluorescence detector for microfluidic diagnostic system |
| US8088616B2 (en) | 2006-03-24 | 2012-01-03 | Handylab, Inc. | Heater unit for microfluidic diagnostic system |
| US7998708B2 (en) | 2006-03-24 | 2011-08-16 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
| US10900066B2 (en) | 2006-03-24 | 2021-01-26 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
| DK3088083T3 (en) | 2006-03-24 | 2018-11-26 | Handylab Inc | Method of carrying out PCR down a multi-track cartridge |
| WO2007111347A1 (ja) * | 2006-03-28 | 2007-10-04 | Universal Bio Research Co., Ltd. | マイクロプレート処理装置およびマイクロプレート処理方法 |
| JP5122091B2 (ja) | 2006-06-13 | 2013-01-16 | ユニバーサル・バイオ・リサーチ株式会社 | 担体封入変形容器、担体封入変形容器処理装置、および担体封入変形容器処理方法 |
| WO2007148734A1 (ja) | 2006-06-20 | 2007-12-27 | Hitachi Metals, Ltd. | 金属微粒子及び生体物質抽出用の磁気ビーズ、並びにそれらの製造方法 |
| JP4804278B2 (ja) | 2006-08-30 | 2011-11-02 | ユニバーサル・バイオ・リサーチ株式会社 | マイクロプレート分割処理装置およびマイクロプレート分割処理方法 |
| EP2091647A2 (en) | 2006-11-14 | 2009-08-26 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
| US7883265B2 (en) * | 2007-06-01 | 2011-02-08 | Applied Biosystems, Llc | Devices, systems, and methods for preparing emulsions |
| JP5232858B2 (ja) * | 2007-06-29 | 2013-07-10 | ベクトン・ディキンソン・アンド・カンパニー | 生物学的試料の成分を抽出および精製するための方法 |
| US9618139B2 (en) | 2007-07-13 | 2017-04-11 | Handylab, Inc. | Integrated heater and magnetic separator |
| US8287820B2 (en) | 2007-07-13 | 2012-10-16 | Handylab, Inc. | Automated pipetting apparatus having a combined liquid pump and pipette head system |
| USD621060S1 (en) | 2008-07-14 | 2010-08-03 | Handylab, Inc. | Microfluidic cartridge |
| JP5651011B2 (ja) | 2007-07-13 | 2015-01-07 | ハンディーラブ インコーポレイテッド | ポリヌクレオチド捕捉材料およびその使用方法 |
| US20090136385A1 (en) | 2007-07-13 | 2009-05-28 | Handylab, Inc. | Reagent Tube |
| US9186677B2 (en) | 2007-07-13 | 2015-11-17 | Handylab, Inc. | Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples |
| US8182763B2 (en) | 2007-07-13 | 2012-05-22 | Handylab, Inc. | Rack for sample tubes and reagent holders |
| US8133671B2 (en) | 2007-07-13 | 2012-03-13 | Handylab, Inc. | Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples |
| US8105783B2 (en) * | 2007-07-13 | 2012-01-31 | Handylab, Inc. | Microfluidic cartridge |
| DE102007045474A1 (de) | 2007-09-21 | 2009-04-02 | Qiagen Gmbh | Vorrichtung und Verfahren zum Behandeln von Flüssigkeiten mit magnetischen Partikeln |
| ES2818194T3 (es) | 2007-10-02 | 2021-04-09 | Labrador Diagnostics Llc | Dispositivos modulares para puntos de atención y usos de los mismos |
| US7850917B2 (en) * | 2008-03-11 | 2010-12-14 | Ortho-Clinical Diagnostics, Inc. | Particle agglutination in a tip |
| US20110009608A1 (en) * | 2008-04-09 | 2011-01-13 | Bioneer Corporation | Automatic refining apparatus, multi-well plate kit and method for extracting hexane from biological samples |
| ES2371185B1 (es) * | 2008-05-30 | 2012-08-07 | Grifols, S.A. | Aparato para la realizacion automatica de analisis de muestras en tarjetas de gel. |
| US20100009351A1 (en) * | 2008-07-11 | 2010-01-14 | Handylab, Inc. | Polynucleotide Capture Materials, and Method of Using Same |
| USD618820S1 (en) | 2008-07-11 | 2010-06-29 | Handylab, Inc. | Reagent holder |
| USD787087S1 (en) | 2008-07-14 | 2017-05-16 | Handylab, Inc. | Housing |
| US11235323B2 (en) | 2008-08-27 | 2022-02-01 | Life Technologies Corporation | Apparatus for and method of processing biological samples |
| WO2010025302A2 (en) | 2008-08-27 | 2010-03-04 | Life Technologies Corporation | Apparatus for and method of processing biological samples |
| US9182395B2 (en) * | 2008-12-25 | 2015-11-10 | Universal Bio Research Co., Ltd. | Method for pretreating specimen and method for assaying biological substance |
| GB2473868A (en) | 2009-09-28 | 2011-03-30 | Invitrogen Dynal As | Apparatus and method of automated processing of biological samples |
| JP5752042B2 (ja) * | 2009-11-13 | 2015-07-22 | ユニバーサル・バイオ・リサーチ株式会社 | 磁性試薬、磁性試薬キット、磁性担体処理方法およびその処理装置 |
| JP5284928B2 (ja) * | 2009-11-20 | 2013-09-11 | 株式会社日立ハイテクノロジーズ | 液体混合方法及び分注装置 |
| JP5846773B2 (ja) | 2010-06-29 | 2016-01-20 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | サンプルの分配 |
| CA2825196C (en) | 2011-01-21 | 2021-01-05 | Theranos, Inc. | Systems and methods for sample use maximization |
| KR101917402B1 (ko) | 2011-02-04 | 2019-01-24 | 유니바사루 바이오 리사치 가부시키가이샤 | 자동 반응ㆍ광측정 장치 및 그 방법 |
| JP6088487B2 (ja) | 2011-04-15 | 2017-03-01 | ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ， Ｄｉｃｋｉｎｓｏｎ Ａｎｄ Ｃｏｍｐａｎｙ | 走査リアルタイムマイクロ流体熱サイクラーと同期熱サイクリング及び走査光学検出の方法 |
| JP5850665B2 (ja) * | 2011-08-02 | 2016-02-03 | 栄研化学株式会社 | 免疫測定装置、免疫測定方法 |
| US9632102B2 (en) | 2011-09-25 | 2017-04-25 | Theranos, Inc. | Systems and methods for multi-purpose analysis |
| US20140170735A1 (en) | 2011-09-25 | 2014-06-19 | Elizabeth A. Holmes | Systems and methods for multi-analysis |
| US9664702B2 (en) | 2011-09-25 | 2017-05-30 | Theranos, Inc. | Fluid handling apparatus and configurations |
| US8475739B2 (en) | 2011-09-25 | 2013-07-02 | Theranos, Inc. | Systems and methods for fluid handling |
| US9268915B2 (en) | 2011-09-25 | 2016-02-23 | Theranos, Inc. | Systems and methods for diagnosis or treatment |
| US9619627B2 (en) | 2011-09-25 | 2017-04-11 | Theranos, Inc. | Systems and methods for collecting and transmitting assay results |
| US10012664B2 (en) | 2011-09-25 | 2018-07-03 | Theranos Ip Company, Llc | Systems and methods for fluid and component handling |
| US9250229B2 (en) | 2011-09-25 | 2016-02-02 | Theranos, Inc. | Systems and methods for multi-analysis |
| US9810704B2 (en) | 2013-02-18 | 2017-11-07 | Theranos, Inc. | Systems and methods for multi-analysis |
| USD692162S1 (en) | 2011-09-30 | 2013-10-22 | Becton, Dickinson And Company | Single piece reagent holder |
| WO2013049706A1 (en) | 2011-09-30 | 2013-04-04 | Becton, Dickinson And Company | Unitized reagent strip |
| EP2773892B1 (en) | 2011-11-04 | 2020-10-07 | Handylab, Inc. | Polynucleotide sample preparation device |
| JP2013122402A (ja) * | 2011-12-09 | 2013-06-20 | Canon Inc | 検体検査用分析装置 |
| EP2618157A1 (en) * | 2012-01-17 | 2013-07-24 | Eppendorf Ag | Laboratory apparatus for treating a sample reception section with a magnetic tool device, magnetic tool device, sample reception device for use with the magnetic tool device and method for performing a work step on at least one fluid sample using a magnetic field |
| CN107881219B (zh) | 2012-02-03 | 2021-09-10 | 贝克顿·迪金森公司 | 用于分子诊断测试分配和测试之间兼容性确定的外部文件 |
| KR102158399B1 (ko) | 2012-08-31 | 2020-09-21 | 유니바사루 바이오 리사치 가부시키가이샤 | 변형요소내장 분주팁, 변형요소내장 분주장치 및 변형요소내장 분주처리방법 |
| US10288606B2 (en) | 2012-10-22 | 2019-05-14 | Universal Bio Research Co., Ltd. | Analysis method and analysis kit for simultaneously detecting or quantitating multiple types of target substances |
| USD962471S1 (en) | 2013-03-13 | 2022-08-30 | Abbott Laboratories | Reagent container |
| USD978375S1 (en) | 2013-03-13 | 2023-02-14 | Abbott Laboratories | Reagent container |
| US9535082B2 (en) | 2013-03-13 | 2017-01-03 | Abbott Laboratories | Methods and apparatus to agitate a liquid |
| US10058866B2 (en) | 2013-03-13 | 2018-08-28 | Abbott Laboratories | Methods and apparatus to mitigate bubble formation in a liquid |
| WO2014144640A1 (en) | 2013-03-15 | 2014-09-18 | Abbott Laboratories | Automated diagnostic analyzers having vertically arranged carousels and related methods |
| ES2901756T3 (es) | 2013-03-15 | 2022-03-23 | Abbott Lab | Analizadores de diagnóstico automatizados que tienen sistemas de pista accesibles por la parte trasera y métodos relacionados |
| EP2972402B1 (en) | 2013-03-15 | 2023-12-20 | Abbott Laboratories | Diagnostic analyzers with pretreatment carousels and related methods |
| US10422806B1 (en) | 2013-07-25 | 2019-09-24 | Theranos Ip Company, Llc | Methods for improving assays of biological samples |
| JP6241537B2 (ja) | 2014-03-14 | 2017-12-06 | 株式会社島津製作所 | 磁性体粒子の操作方法および磁性体粒子操作用デバイス |
| WO2016031705A1 (ja) * | 2014-08-26 | 2016-03-03 | ユニバーサル・バイオ・リサーチ株式会社 | 可変ピッチ分注装置を利用した磁性粒子反応制御装置およびその反応制御方法 |
| CN107148479A (zh) | 2014-09-04 | 2017-09-08 | 赛拉诺斯股份有限公司 | 病原体和抗微生物剂抗性检测 |
| WO2016079779A1 (ja) | 2014-11-17 | 2016-05-26 | 株式会社島津製作所 | 粒子操作方法および粒子操作用装置 |
| JP6332012B2 (ja) | 2014-12-22 | 2018-05-30 | 株式会社島津製作所 | 磁性体粒子操作用装置 |
| WO2016113883A1 (ja) | 2015-01-15 | 2016-07-21 | 株式会社島津製作所 | 磁性体粒子操作用デバイスおよび磁性体粒子の操作方法 |
| JP6479956B2 (ja) | 2015-02-23 | 2019-03-06 | 株式会社日立ハイテクノロジーズ | 核酸分析装置 |
| JP6801656B2 (ja) | 2015-07-07 | 2020-12-16 | コニカミノルタ株式会社 | 検出装置および検出方法 |
| EP3413056B1 (en) * | 2016-02-02 | 2019-12-18 | Konica Minolta, Inc. | Liquid delivery method, and detection system using said method |
| CN119056579A (zh) * | 2016-03-18 | 2024-12-03 | 安德鲁联合有限公司 | 液体处理器的尖端中的珠子操作方法及装置 |
| EP3467512A4 (en) | 2016-05-25 | 2020-02-19 | Universal Bio Research Co., Ltd. | SAMPLE PROCESSING AND MEASUREMENT SYSTEM |
| TWI766942B (zh) | 2017-02-13 | 2022-06-11 | 美商海科生醫有限責任公司 | 透過利用瞬態和穩態間隔振動移液管來混合流體或介質的設備和方法 |
| US11498064B2 (en) | 2017-03-28 | 2022-11-15 | Universal Bio Research Co., Ltd. | Photometric dispensing nozzle unit, photometric dispensing apparatus, and photometric dispensing method |
| JP7050757B2 (ja) | 2017-03-29 | 2022-04-08 | ユニバーサル・バイオ・リサーチ株式会社 | 検体処理測定システム |
| CN108795701A (zh) * | 2018-07-27 | 2018-11-13 | 山东见微生物科技有限公司 | 核酸提取机构、样本处理设备以及核酸提取方法 |
| JP3220518U (ja) | 2018-11-14 | 2019-03-14 | 株式会社島津製作所 | 磁性体粒子操作用装置 |
| US11623188B2 (en) | 2018-11-28 | 2023-04-11 | V&P Scientific, Inc. | Spinning vessel systems and methods for mixing, suspending particulates, aliquoting, washing magnetic beads, and concentrating analytes |
| KR102105639B1 (ko) * | 2019-03-28 | 2020-04-28 | 주식회사 엘지화학 | 면역 검사 장치 및 면역 검사 방법 |
| KR102102988B1 (ko) | 2019-03-28 | 2020-04-22 | 주식회사 엘지화학 | 면역 검사 장치 및 면역 검사 방법 |
| US11684926B2 (en) * | 2019-07-14 | 2023-06-27 | Zhuhai Sanmed Biotech Ltd. | System and processes for isolation and enrichment by magnetic separation |
| KR102375817B1 (ko) * | 2020-02-14 | 2022-03-18 | 주식회사 디앤에이보이 | 검체 분석 장치 |
| EP4127731A1 (en) | 2020-04-03 | 2023-02-08 | Andrew Alliance S.A | Bead manipulation in a consumable |
| US11480565B2 (en) * | 2020-06-12 | 2022-10-25 | Bio-Rad Laboratories, Inc. | Automated immunoassay |
| US20230341431A1 (en) * | 2020-06-23 | 2023-10-26 | Hitachi High-Tech Corporation | Automatic analyzer and analysis method |
| CN112282711A (zh) * | 2020-09-28 | 2021-01-29 | 中国石油天然气集团有限公司 | 一种液体加注器及其对仪器的注液方法 |
| WO2022230448A1 (ja) | 2021-04-28 | 2022-11-03 | ユニバーサル・バイオ・リサーチ株式会社 | 分注装置、及び検体処理測定システム |
| US20240319052A1 (en) | 2021-07-26 | 2024-09-26 | Universal Bio Research Co., Ltd. | Bio-related substance extracting device and processing system |
| CN114247492B (zh) * | 2021-12-23 | 2023-02-07 | 安徽阜邦生物科技有限公司 | 一种化工检验用可快速固定的检测设备及其使用方法 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6168563A (ja) * | 1984-09-12 | 1986-04-08 | Hayashi Kogyo Kk | 分注機における全自動チツプ供給挿着装置 |
| DE3664005D1 (en) * | 1985-10-09 | 1989-07-20 | Kontron Holding Ag | Liquid-withdrawing device |
| AU590418B2 (en) * | 1986-05-21 | 1989-11-02 | Tosoh Corporation | Pipetting device having an automatic mechanism for replacing nozzle tips |
| JPS6370169A (ja) * | 1986-09-11 | 1988-03-30 | Toshiba Corp | プロ−ブ洗浄方法 |
| IL94212A0 (en) * | 1989-07-24 | 1991-01-31 | Tri Tech Partners And Triton B | Automated analytical apparatus and method |
| FR2654836B1 (fr) * | 1989-11-17 | 1994-01-28 | Biotrol Sa Laboratoires | Appareil d'execution automatique d'un immunodosage en plusieurs etapes successives d'au moins une substance biologique dans une pluralite d'echantillons biologiques, procede et reactif mettant en óoeuvre ledit appareil. |
| JPH03175361A (ja) * | 1989-12-04 | 1991-07-30 | Nittec Co Ltd | 免疫自動分析装置 |
| US5183638A (en) * | 1989-12-04 | 1993-02-02 | Kabushiki Kaisha Nittec | Automatic immunity analysis apparatus with magnetic particle separation |
| JP2525063B2 (ja) * | 1990-03-03 | 1996-08-14 | 株式会社日立製作所 | 自動分析方法 |
| TW199858B (Direct) * | 1990-03-30 | 1993-02-11 | Fujirebio Kk | |
| US5576215A (en) * | 1991-06-03 | 1996-11-19 | Abbott Laboratories | Adaptive scheduling system and method for operating a biological sample analyzer with variable interval periods |
| US5289385A (en) * | 1991-06-03 | 1994-02-22 | Abbott Laboratories | Adaptive scheduling system and method for operating a biological sample analyzer with variable rinsing |
| JP2795564B2 (ja) * | 1991-10-08 | 1998-09-10 | アロカ 株式会社 | 高粘性液体の希釈方法 |
| US5646049A (en) * | 1992-03-27 | 1997-07-08 | Abbott Laboratories | Scheduling operation of an automated analytical system |
| JP2745091B2 (ja) * | 1992-04-03 | 1998-04-28 | 東亞医用電子株式会社 | 免疫凝集測定装置 |
| JP3142873B2 (ja) * | 1993-02-01 | 2001-03-07 | ラブシステムズ オユ | 磁性粒子の特異的結合による検定の方法および装置 |
| FI932866A0 (fi) | 1993-06-21 | 1993-06-21 | Labsystems Oy | Separeringsfoerfarande |
| ATE212723T1 (de) * | 1993-09-17 | 2002-02-15 | Hoffmann La Roche | Analysengerät mit einer vorrichtung zum abtrennen magnetischer mikropartikel |
| JP3115501B2 (ja) * | 1994-06-15 | 2000-12-11 | プレシジョン・システム・サイエンス株式会社 | 分注機を利用した磁性体の脱着制御方法及びこの方法によって処理される各種装置 |
| DE4423878A1 (de) * | 1994-07-07 | 1996-01-11 | Boehringer Mannheim Gmbh | Vorrichtung und Verfahren zum Abscheiden von magnetischen Mikropartikeln |
-
1996
- 1996-05-20 WO PCT/JP1996/001333 patent/WO1997044671A1/ja not_active Ceased
- 1996-05-20 US US09/197,408 patent/US6509193B1/en not_active Expired - Lifetime
- 1996-05-20 DE DE69638151T patent/DE69638151D1/de not_active Expired - Lifetime
- 1996-05-20 CA CA002255658A patent/CA2255658C/en not_active Expired - Fee Related
- 1996-05-20 AU AU57030/96A patent/AU738336B2/en not_active Ceased
- 1996-05-20 JP JP54197597A patent/JP3682302B2/ja not_active Expired - Lifetime
- 1996-05-20 EP EP96915198A patent/EP0965842B1/en not_active Expired - Lifetime
-
1999
- 1999-02-05 NO NO19990558A patent/NO330495B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69638151D1 (de) | 2010-04-29 |
| CA2255658C (en) | 2007-07-17 |
| EP0965842A1 (en) | 1999-12-22 |
| AU5703096A (en) | 1997-12-09 |
| AU738336B2 (en) | 2001-09-13 |
| WO1997044671A1 (fr) | 1997-11-27 |
| EP0965842B1 (en) | 2010-03-17 |
| JP3682302B2 (ja) | 2005-08-10 |
| EP0965842A4 (Direct) | 1999-12-22 |
| US6509193B1 (en) | 2003-01-21 |
| NO990558D0 (no) | 1999-02-05 |
| CA2255658A1 (en) | 1997-11-27 |
| NO990558L (no) | 1999-02-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO330495B1 (no) | Kontrollmetode og apparat for kontroll av magnetiske partikler ved hjelp av en provefordeler | |
| US11275095B2 (en) | Sample pretreatment apparatus, robotic arm, and sample pretreatment method | |
| US20210302456A1 (en) | Sample analysis device | |
| RU2562572C2 (ru) | Автоматическая система для пцр в реальном времени для различных анализов биологического образца | |
| JP3652424B2 (ja) | 自動分析装置及びその方法 | |
| CN101581721B (zh) | 具有至少一个在离心循环过程中提供预先的凝聚评估的成像仪的免疫诊断检测设备 | |
| EP2817606B1 (en) | Instrument for pretreating cell samples | |
| JP3115501B2 (ja) | 分注機を利用した磁性体の脱着制御方法及びこの方法によって処理される各種装置 | |
| JPWO1997044671A1 (ja) | 分注機による磁性体粒子の制御方法およびその装置 | |
| JP6449017B2 (ja) | 直動型反応処理装置およびその方法 | |
| JP4629675B2 (ja) | オペレーター不要のプログラム可能な試料調製および分析システム | |
| US20110215118A1 (en) | Dispensing cylinder, large capacity dispensing device and method of using large capacity dispensing device | |
| US8337755B2 (en) | Operator independent programmable sample preparation and analysis system | |
| EP1122544A1 (en) | Automatic separator/extractor and control method therefor | |
| CN105517711A (zh) | 用于使反应容器单元受离心力作用的离心机与方法 | |
| JPS61502078A (ja) | 自動化検定機械およびアッセイトレイ | |
| CN111279197A (zh) | 磁分离方法及自动分析装置 | |
| US11761972B2 (en) | Automated analysis device | |
| JPH11242033A (ja) | 分注機を利用した定性／定量解析方法及びこの方法によって処理される各種装置 | |
| JPH11262678A (ja) | 分注機を利用した磁性体の脱着制御方法及びこの方法によって処理される各種装置 | |
| CN116348753A (zh) | 试样制备方法、细胞分析方法、试样制备装置以及细胞分析装置 | |
| US20250083143A1 (en) | Examination apparatus | |
| JPH06288879A (ja) | 多種液体用連続処理具の自動洗浄装置 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |