NO330278B1 - Anvendelse av en CC-kjemokinmutant i fremstillingen av en farmasoytisk sammensetning til behandlingen av multippel sklerose og/eller andre demyelinerende sykdommer, farmasoytisk sammensetning omfattende mutantene, trunkert og mutert human RANTES og rekombinant fremgangsmate for fremstilling av samme,DNA-molekyl som koder for dette, ekspresjonsvektor som omfatter DNA-molekylet og vertscelle som omfatter ekspresjonsvektoren - Google Patents
Anvendelse av en CC-kjemokinmutant i fremstillingen av en farmasoytisk sammensetning til behandlingen av multippel sklerose og/eller andre demyelinerende sykdommer, farmasoytisk sammensetning omfattende mutantene, trunkert og mutert human RANTES og rekombinant fremgangsmate for fremstilling av samme,DNA-molekyl som koder for dette, ekspresjonsvektor som omfatter DNA-molekylet og vertscelle som omfatter ekspresjonsvektoren Download PDFInfo
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- NO330278B1 NO330278B1 NO20031525A NO20031525A NO330278B1 NO 330278 B1 NO330278 B1 NO 330278B1 NO 20031525 A NO20031525 A NO 20031525A NO 20031525 A NO20031525 A NO 20031525A NO 330278 B1 NO330278 B1 NO 330278B1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/521—Chemokines
- C07K14/523—Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Psychiatry (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00121665 | 2000-10-04 | ||
PCT/EP2001/011428 WO2002028419A2 (en) | 2000-10-04 | 2001-10-03 | Chemokine mutants in the treatment of multiple sclerosis |
Publications (3)
Publication Number | Publication Date |
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NO20031525D0 NO20031525D0 (no) | 2003-04-03 |
NO20031525L NO20031525L (no) | 2003-04-03 |
NO330278B1 true NO330278B1 (no) | 2011-03-21 |
Family
ID=8170011
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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NO20031525A NO330278B1 (no) | 2000-10-04 | 2003-04-03 | Anvendelse av en CC-kjemokinmutant i fremstillingen av en farmasoytisk sammensetning til behandlingen av multippel sklerose og/eller andre demyelinerende sykdommer, farmasoytisk sammensetning omfattende mutantene, trunkert og mutert human RANTES og rekombinant fremgangsmate for fremstilling av samme,DNA-molekyl som koder for dette, ekspresjonsvektor som omfatter DNA-molekylet og vertscelle som omfatter ekspresjonsvektoren |
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US (1) | US7402303B2 (sl) |
EP (1) | EP1326628B1 (sl) |
JP (1) | JP3908165B2 (sl) |
KR (1) | KR100837898B1 (sl) |
CN (1) | CN1285381C (sl) |
AR (1) | AR030854A1 (sl) |
AT (1) | ATE265222T1 (sl) |
AU (2) | AU2002215919B2 (sl) |
BG (1) | BG66137B1 (sl) |
BR (1) | BR0114407A (sl) |
CA (1) | CA2423616C (sl) |
CZ (1) | CZ303409B6 (sl) |
DE (1) | DE60103078T2 (sl) |
DK (1) | DK1326628T3 (sl) |
EA (1) | EA006137B1 (sl) |
EE (1) | EE05174B1 (sl) |
ES (1) | ES2217199T3 (sl) |
HK (1) | HK1062811A1 (sl) |
HR (1) | HRP20030215B1 (sl) |
HU (1) | HUP0302194A3 (sl) |
IL (2) | IL155178A0 (sl) |
MX (1) | MXPA03003008A (sl) |
NO (1) | NO330278B1 (sl) |
PL (1) | PL204231B1 (sl) |
PT (1) | PT1326628E (sl) |
RS (1) | RS50738B (sl) |
SI (1) | SI1326628T1 (sl) |
SK (1) | SK287523B6 (sl) |
UA (1) | UA77950C2 (sl) |
WO (1) | WO2002028419A2 (sl) |
ZA (1) | ZA200302315B (sl) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE421974T1 (de) | 2001-12-17 | 2009-02-15 | Serono Lab | Chemokine mutanten, die als chemokine antagonisten wirken |
CA2480692A1 (en) | 2002-04-04 | 2003-10-16 | Applied Research Systems Ars Holding N.V. | Chemokines mutants having improved oral bioavailability |
DE60320848D1 (de) | 2002-12-23 | 2008-06-19 | Serono Lab | Verwendung von cc-chemokine ccl5/rantes mutanten zur behandlung von lebererkrankungen |
AU2004283910A1 (en) * | 2003-10-22 | 2005-05-06 | Laboratoires Serono Sa | Novel CXCL8 antagonists |
AT412785B (de) * | 2003-12-04 | 2005-07-25 | Kungl Andreas J Dr | Gag-bindungsproteine |
DK1439191T3 (da) * | 2004-01-19 | 2006-08-14 | Ares Trading Sa | Proces til oprensning af bakterielt udtrykte proteiner |
GB0412400D0 (en) * | 2004-06-03 | 2004-07-07 | Univ Newcastle | Treatment of inflammatory conditions |
EP1760110B1 (en) * | 2005-09-03 | 2011-11-02 | Samsung SDI Co., Ltd. | Polybenzoxazine-based compound, electrolyte membrane including the same, and fuel cell employing the electrolyte membrane |
GB0614755D0 (en) | 2006-07-25 | 2006-09-06 | Univ Geneve | Cytokine derivatives |
EP2185719B1 (en) | 2007-08-02 | 2013-11-13 | NovImmune SA | Anti-rantes antibodies and methods of use thereof |
CN102781952B (zh) * | 2010-02-08 | 2015-09-02 | 宾夕法尼亚大学托管会 | 编码rantes的核酸分子、包含其的组合物以及其使用方法 |
WO2019229615A1 (en) | 2018-05-28 | 2019-12-05 | Université De Genève | Methods of inhibiting cerebral inflammation |
WO2022093857A1 (en) * | 2020-10-26 | 2022-05-05 | City Of Hope | Oncolytic virus compositions and methods for the treatment of cancer |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5739103A (en) | 1993-11-12 | 1998-04-14 | Dana-Farber Cancer Institute | Chemokine N-terminal deletion mutations |
WO1998006751A1 (en) * | 1996-08-16 | 1998-02-19 | Research Corporation Technologies, Inc. | Mcp-3, rantes and mip-1alpha receptor antagonists |
EP0906954A1 (en) * | 1997-09-29 | 1999-04-07 | Applied Research Systems ARS Holding N.V. | Amino-terminal truncated c-c chemokines as chemokine antagonist |
DE69832216T2 (de) | 1997-12-23 | 2006-05-24 | Fondazione Centro San Raffaele Del Monte Tabor | RANTES-Mutanten und therapeutische Anwendungen davon |
WO2000044408A2 (en) | 1999-01-29 | 2000-08-03 | Millennium Pharmaceuticals, Inc. | Method of treating demyelinating inflammatory disease using ccr1 antagonists |
-
2001
- 2001-03-10 UA UA2003044038A patent/UA77950C2/uk unknown
- 2001-10-03 AU AU2002215919A patent/AU2002215919B2/en not_active Ceased
- 2001-10-03 ES ES01986265T patent/ES2217199T3/es not_active Expired - Lifetime
- 2001-10-03 HU HU0302194A patent/HUP0302194A3/hu unknown
- 2001-10-03 WO PCT/EP2001/011428 patent/WO2002028419A2/en active IP Right Grant
- 2001-10-03 DK DK01986265T patent/DK1326628T3/da active
- 2001-10-03 JP JP2002532243A patent/JP3908165B2/ja not_active Expired - Fee Related
- 2001-10-03 PL PL362350A patent/PL204231B1/pl not_active IP Right Cessation
- 2001-10-03 CZ CZ20030947A patent/CZ303409B6/cs not_active IP Right Cessation
- 2001-10-03 RS YUP-257/03A patent/RS50738B/sr unknown
- 2001-10-03 EE EEP200300139A patent/EE05174B1/xx not_active IP Right Cessation
- 2001-10-03 CN CNB018199178A patent/CN1285381C/zh not_active Expired - Fee Related
- 2001-10-03 SK SK406-2003A patent/SK287523B6/sk not_active IP Right Cessation
- 2001-10-03 AT AT01986265T patent/ATE265222T1/de active
- 2001-10-03 PT PT01986265T patent/PT1326628E/pt unknown
- 2001-10-03 KR KR1020037004599A patent/KR100837898B1/ko not_active IP Right Cessation
- 2001-10-03 ZA ZA200302315A patent/ZA200302315B/en unknown
- 2001-10-03 US US10/398,457 patent/US7402303B2/en not_active Expired - Fee Related
- 2001-10-03 EA EA200300439A patent/EA006137B1/ru not_active IP Right Cessation
- 2001-10-03 IL IL15517801A patent/IL155178A0/xx unknown
- 2001-10-03 SI SI200130130T patent/SI1326628T1/sl unknown
- 2001-10-03 CA CA2423616A patent/CA2423616C/en not_active Expired - Fee Related
- 2001-10-03 BR BR0114407-3A patent/BR0114407A/pt not_active IP Right Cessation
- 2001-10-03 AU AU1591902A patent/AU1591902A/xx active Pending
- 2001-10-03 DE DE60103078T patent/DE60103078T2/de not_active Expired - Lifetime
- 2001-10-03 EP EP01986265A patent/EP1326628B1/en not_active Expired - Lifetime
- 2001-10-03 MX MXPA03003008A patent/MXPA03003008A/es active IP Right Grant
- 2001-10-04 AR ARP010104684A patent/AR030854A1/es unknown
-
2003
- 2003-03-20 HR HR20030215A patent/HRP20030215B1/xx not_active IP Right Cessation
- 2003-03-28 BG BG107685A patent/BG66137B1/bg unknown
- 2003-04-01 IL IL155178A patent/IL155178A/en not_active IP Right Cessation
- 2003-04-03 NO NO20031525A patent/NO330278B1/no not_active IP Right Cessation
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2004
- 2004-08-02 HK HK04105657A patent/HK1062811A1/xx not_active IP Right Cessation
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