NO329118B1 - Sterilt topisk oftalmisk preparat samt anvendelse av en forbindelse for fremstilling av et medikament - Google Patents
Sterilt topisk oftalmisk preparat samt anvendelse av en forbindelse for fremstilling av et medikament Download PDFInfo
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- NO329118B1 NO329118B1 NO19993777A NO993777A NO329118B1 NO 329118 B1 NO329118 B1 NO 329118B1 NO 19993777 A NO19993777 A NO 19993777A NO 993777 A NO993777 A NO 993777A NO 329118 B1 NO329118 B1 NO 329118B1
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- Prior art keywords
- stated
- compound
- alkyl
- formula
- topical ophthalmic
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- PGAVKCOVUIYSFO-UHFFFAOYSA-N uridine-triphosphate Natural products OC1C(O)C(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)OC1N1C(=O)NC(=O)C=C1 PGAVKCOVUIYSFO-UHFFFAOYSA-N 0.000 claims abstract description 23
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- PCDQPRRSZKQHHS-UHFFFAOYSA-N Cytidine 5'-triphosphate Natural products O=C1N=C(N)C=CN1C1C(O)C(O)C(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O1 PCDQPRRSZKQHHS-UHFFFAOYSA-N 0.000 claims abstract description 8
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- YDHWWBZFRZWVHO-UHFFFAOYSA-H [oxido-[oxido(phosphonatooxy)phosphoryl]oxyphosphoryl] phosphate Chemical compound [O-]P([O-])(=O)OP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O YDHWWBZFRZWVHO-UHFFFAOYSA-H 0.000 claims description 9
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-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Ophthalmology & Optometry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/797,472 US5900407A (en) | 1997-02-06 | 1997-02-06 | Method of treating dry eye disease with uridine triphosphates and related compounds |
PCT/US1998/002701 WO1998034593A1 (fr) | 1997-02-06 | 1998-02-06 | Procede pour traiter la kerotoconjonctivite seche grace a des agonistes recepteurs purinergiques |
Publications (3)
Publication Number | Publication Date |
---|---|
NO993777D0 NO993777D0 (no) | 1999-08-04 |
NO993777L NO993777L (no) | 1999-10-05 |
NO329118B1 true NO329118B1 (no) | 2010-08-30 |
Family
ID=25170925
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19993777A NO329118B1 (no) | 1997-02-06 | 1999-08-04 | Sterilt topisk oftalmisk preparat samt anvendelse av en forbindelse for fremstilling av et medikament |
Country Status (20)
Country | Link |
---|---|
US (6) | US5900407A (fr) |
EP (1) | EP1003474B1 (fr) |
JP (3) | JP3652707B2 (fr) |
KR (1) | KR100378443B1 (fr) |
CN (1) | CN1151775C (fr) |
AT (1) | ATE428400T1 (fr) |
AU (1) | AU735684B2 (fr) |
BR (1) | BR9809562A (fr) |
CA (1) | CA2280183C (fr) |
DE (1) | DE69840746D1 (fr) |
DK (1) | DK1003474T3 (fr) |
ES (1) | ES2325892T3 (fr) |
HK (1) | HK1025915A1 (fr) |
ID (1) | ID23375A (fr) |
MY (1) | MY120023A (fr) |
NO (1) | NO329118B1 (fr) |
NZ (1) | NZ337405A (fr) |
PT (1) | PT1003474E (fr) |
WO (1) | WO1998034593A1 (fr) |
ZA (1) | ZA98979B (fr) |
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1997
- 1997-02-06 US US08/797,472 patent/US5900407A/en not_active Expired - Lifetime
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1998
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- 1998-02-06 ZA ZA98979A patent/ZA98979B/xx unknown
- 1998-02-06 NZ NZ337405A patent/NZ337405A/en not_active IP Right Cessation
- 1998-02-06 AT AT98907434T patent/ATE428400T1/de active
- 1998-02-06 DE DE69840746T patent/DE69840746D1/de not_active Expired - Lifetime
- 1998-02-06 BR BR9809562-5A patent/BR9809562A/pt not_active Application Discontinuation
- 1998-02-06 EP EP98907434A patent/EP1003474B1/fr not_active Expired - Lifetime
- 1998-02-06 ES ES98907434T patent/ES2325892T3/es not_active Expired - Lifetime
- 1998-02-06 KR KR10-1999-7007113A patent/KR100378443B1/ko active IP Right Review Request
- 1998-02-06 CA CA002280183A patent/CA2280183C/fr not_active Expired - Lifetime
- 1998-02-06 PT PT98907434T patent/PT1003474E/pt unknown
- 1998-02-06 CN CNB988032619A patent/CN1151775C/zh not_active Expired - Lifetime
- 1998-02-06 AU AU63241/98A patent/AU735684B2/en not_active Expired
- 1998-02-06 US US09/171,169 patent/US6887858B1/en not_active Expired - Lifetime
- 1998-02-06 WO PCT/US1998/002701 patent/WO1998034593A1/fr active IP Right Grant
- 1998-02-06 ID IDW990977A patent/ID23375A/id unknown
- 1998-02-06 MY MYPI98000483A patent/MY120023A/en unknown
- 1998-02-06 JP JP53505498A patent/JP3652707B2/ja not_active Expired - Lifetime
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1999
- 1999-08-04 NO NO19993777A patent/NO329118B1/no not_active IP Right Cessation
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2000
- 2000-08-25 HK HK00105346A patent/HK1025915A1/xx not_active IP Right Cessation
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2002
- 2002-01-03 US US10/041,826 patent/US6916794B2/en not_active Expired - Lifetime
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2004
- 2004-09-13 JP JP2004265998A patent/JP4664027B2/ja not_active Expired - Lifetime
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2005
- 2005-04-25 US US11/114,957 patent/US7235535B2/en not_active Expired - Fee Related
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2007
- 2007-06-20 US US11/821,091 patent/US7759322B2/en not_active Expired - Lifetime
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2009
- 2009-12-11 JP JP2009281951A patent/JP5373576B2/ja not_active Expired - Lifetime
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2010
- 2010-06-28 US US12/825,051 patent/US8097600B2/en not_active Expired - Fee Related
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Owner name: MERCK SHARP & DOHME CORP, US |
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MK1K | Patent expired |