NO328753B1 - Xantin-fosfodiesterase V-inhibitorer - Google Patents
Xantin-fosfodiesterase V-inhibitorer Download PDFInfo
- Publication number
- NO328753B1 NO328753B1 NO20031238A NO20031238A NO328753B1 NO 328753 B1 NO328753 B1 NO 328753B1 NO 20031238 A NO20031238 A NO 20031238A NO 20031238 A NO20031238 A NO 20031238A NO 328753 B1 NO328753 B1 NO 328753B1
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- Norway
- Prior art keywords
- pde
- compound
- pharmaceutically acceptable
- treatment
- acceptable salt
- Prior art date
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Classifications
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- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
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- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
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- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Ophthalmology & Optometry (AREA)
- Pulmonology (AREA)
- Reproductive Health (AREA)
- Emergency Medicine (AREA)
- Transplantation (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23356700P | 2000-09-19 | 2000-09-19 | |
| PCT/US2001/028983 WO2002024698A1 (en) | 2000-09-19 | 2001-09-17 | Xanthine phosphodiesterase v inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20031238D0 NO20031238D0 (no) | 2003-03-18 |
| NO20031238L NO20031238L (no) | 2003-05-14 |
| NO328753B1 true NO328753B1 (no) | 2010-05-03 |
Family
ID=22877764
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20031238A NO328753B1 (no) | 2000-09-19 | 2003-03-18 | Xantin-fosfodiesterase V-inhibitorer |
Country Status (30)
| Country | Link |
|---|---|
| US (6) | US6821978B2 (xx) |
| EP (1) | EP1319003B1 (xx) |
| JP (2) | JP4015547B2 (xx) |
| KR (1) | KR100610417B1 (xx) |
| CN (1) | CN1252071C (xx) |
| AR (1) | AR035199A1 (xx) |
| AT (1) | ATE433451T1 (xx) |
| AU (2) | AU2001291022B2 (xx) |
| BR (1) | BR0113953A (xx) |
| CA (1) | CA2421910C (xx) |
| CY (1) | CY1109329T1 (xx) |
| DE (1) | DE60138955D1 (xx) |
| DK (1) | DK1319003T3 (xx) |
| EC (1) | ECSP034519A (xx) |
| ES (1) | ES2326956T3 (xx) |
| HK (1) | HK1056550A1 (xx) |
| HU (1) | HUP0303016A3 (xx) |
| IL (1) | IL154839A0 (xx) |
| MX (1) | MXPA03002361A (xx) |
| NO (1) | NO328753B1 (xx) |
| NZ (1) | NZ524433A (xx) |
| PE (1) | PE20020469A1 (xx) |
| PL (1) | PL205188B1 (xx) |
| PT (1) | PT1319003E (xx) |
| RU (1) | RU2302420C9 (xx) |
| SI (1) | SI1319003T1 (xx) |
| SK (1) | SK3192003A3 (xx) |
| TW (1) | TWI241301B (xx) |
| WO (1) | WO2002024698A1 (xx) |
| ZA (1) | ZA200301863B (xx) |
Families Citing this family (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6821978B2 (en) * | 2000-09-19 | 2004-11-23 | Schering Corporation | Xanthine phosphodiesterase V inhibitors |
| SK288003B6 (sk) * | 2001-02-24 | 2012-10-02 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Xanthin derivatives, method for the preparation thereof, pharmaceutical composition containing thereof and their use |
| PT1243263E (pt) * | 2001-03-21 | 2003-03-31 | Sanol Arznei Schwarz Gmbh | Nova utilizacao de uma classe peptidica de composto para o tratamento de alodinia ou de outros tipos diferentes de dor cronica ou fantasma |
| US6869947B2 (en) | 2001-07-03 | 2005-03-22 | Novo Nordisk A/S | Heterocyclic compounds that are inhibitors of the enzyme DPP-IV |
| WO2003004496A1 (en) * | 2001-07-03 | 2003-01-16 | Novo Nordisk A/S | Dpp-iv-inhibiting purine derivatives for the treatment of diabetes |
| EP1463727A2 (en) * | 2001-09-19 | 2004-10-06 | Novo Nordisk A/S | Heterocyclic compounds that are inhibitors of the enzyme dpp-iv |
| CN1585771A (zh) * | 2001-11-09 | 2005-02-23 | 先灵公司 | 多环鸟嘌呤衍生物磷酸二酯酶v抑制剂 |
| CA2470210A1 (en) * | 2001-12-17 | 2003-06-26 | Altana Pharma Ag | Use of selective pde5 inhibitors for treating partial and global respiratory failure |
| US20030181461A1 (en) * | 2002-01-25 | 2003-09-25 | Lautt Wilfred Wayne | Use of phosphodiesterase antagonists to treat insulin resistance |
| ES2299720T3 (es) * | 2002-05-31 | 2008-06-01 | Schering Corporation | Formas polimorfas de un inhibidor de xantina-fosfodiesterasa v. |
| SI1509525T1 (sl) | 2002-05-31 | 2006-12-31 | Schering Corp | Postopek priprave inhibitorjev ksantinske fosfodiesteraze V in njihovih prekurzorjev |
| CN101538224A (zh) * | 2002-05-31 | 2009-09-23 | 先灵公司 | 制备黄嘌呤磷酸二酯酶v抑制剂及其前体的方法 |
| JP4491344B2 (ja) * | 2002-06-17 | 2010-06-30 | グラクソ グループ リミテッド | 肝ｘ受容体アゴニストとしてのプリン誘導体 |
| US7407955B2 (en) | 2002-08-21 | 2008-08-05 | Boehringer Ingelheim Pharma Gmbh & Co., Kg | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions |
| US7569574B2 (en) | 2002-08-22 | 2009-08-04 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Purine derivatives, the preparation thereof and their use as pharmaceutical compositions |
| US7495005B2 (en) * | 2002-08-22 | 2009-02-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Xanthine derivatives, their preparation and their use in pharmaceutical compositions |
| US7482337B2 (en) * | 2002-11-08 | 2009-01-27 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions |
| DE10254304A1 (de) * | 2002-11-21 | 2004-06-03 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Xanthinderivate, deren Herstellung und deren Verwendung als Arzneimittel |
| US7566707B2 (en) | 2003-06-18 | 2009-07-28 | Boehringer Ingelheim International Gmbh | Imidazopyridazinone and imidazopyridone derivatives, the preparation thereof and their use as pharmaceutical compositions |
| JP2007500714A (ja) * | 2003-07-31 | 2007-01-18 | シェーリング コーポレイション | 勃起不全を処置するのに有用なキサンチンホスホジエステラーゼ５インヒビターの代謝物およびそれらの誘導体 |
| JPWO2005021550A1 (ja) * | 2003-08-29 | 2006-10-26 | 大日本住友製薬株式会社 | 二環性ピラゾール誘導体 |
| TW200526664A (en) * | 2003-11-21 | 2005-08-16 | Schering Corp | Phosphodiesterase V inhibitor formulation |
| DE10355304A1 (de) | 2003-11-27 | 2005-06-23 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue 8-(Piperazin-1-yl)-und 8-([1,4]Diazepan-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel |
| DE602004020657D1 (de) * | 2003-12-02 | 2009-05-28 | Sanol Arznei Schwarz Gmbh | Neue verwendung von peptidverbindungen zur behandlung ovn zentralen neuropathischen schmerzen |
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