NO326241B1 - 17 alfa-alkyl-17 beta-oksy-ostratriener og mellomprodukter for fremstilling av disse, anvendelse av 17 alfa-alkyl-17 beta-oksy-ostratrienene til fremstilling av legemidler samt farmasoytiske preparater - Google Patents
17 alfa-alkyl-17 beta-oksy-ostratriener og mellomprodukter for fremstilling av disse, anvendelse av 17 alfa-alkyl-17 beta-oksy-ostratrienene til fremstilling av legemidler samt farmasoytiske preparater Download PDFInfo
- Publication number
- NO326241B1 NO326241B1 NO20042694A NO20042694A NO326241B1 NO 326241 B1 NO326241 B1 NO 326241B1 NO 20042694 A NO20042694 A NO 20042694A NO 20042694 A NO20042694 A NO 20042694A NO 326241 B1 NO326241 B1 NO 326241B1
- Authority
- NO
- Norway
- Prior art keywords
- methyl
- radical
- fluoro
- amino
- pentyl
- Prior art date
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Classifications
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- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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- A—HUMAN NECESSITIES
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- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
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- A61P35/00—Antineoplastic agents
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10159217A DE10159217A1 (de) | 2001-11-27 | 2001-11-27 | 17alpha-Alkyl-17ß-oxy-estratriene und Zwischenprodukte zu deren Herstellung, Verwendung der 17alpha-Alkyl-17ß-oxy-estratriene zur Herstellung von Arzneimitteln sowie pharmazeutische Präparate |
PCT/EP2002/013484 WO2003045972A1 (de) | 2001-11-27 | 2002-11-27 | 17α-ALKYL-17β-OXY-ESTRATRIENE UND ZWISCHENPRODUKTE ZU DEREN HERSTELLUNG, VERWENDUNG DER 17α-ALKYL-17β-OXY-ESTRATRIENE ZUR HERSTELLUNG VON ARZNEIMITTELN SOWIE PHARMAZEUTISCHE PRÄPARATE |
Publications (2)
Publication Number | Publication Date |
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NO20042694L NO20042694L (no) | 2004-07-22 |
NO326241B1 true NO326241B1 (no) | 2008-10-27 |
Family
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Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20042694A NO326241B1 (no) | 2001-11-27 | 2004-06-25 | 17 alfa-alkyl-17 beta-oksy-ostratriener og mellomprodukter for fremstilling av disse, anvendelse av 17 alfa-alkyl-17 beta-oksy-ostratrienene til fremstilling av legemidler samt farmasoytiske preparater |
NO20044192A NO20044192L (no) | 2001-11-27 | 2004-10-04 | 17alfa-alkyl-17beta-oksy-ostratriener og farmasoytiske preparater |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20044192A NO20044192L (no) | 2001-11-27 | 2004-10-04 | 17alfa-alkyl-17beta-oksy-ostratriener og farmasoytiske preparater |
Country Status (26)
Country | Link |
---|---|
US (2) | US7018994B2 (ko) |
EP (2) | EP1916254A3 (ko) |
JP (3) | JP2005513039A (ko) |
KR (1) | KR100956912B1 (ko) |
CN (2) | CN1325507C (ko) |
AR (1) | AR037674A1 (ko) |
AT (1) | ATE396198T1 (ko) |
AU (1) | AU2002360949A1 (ko) |
BR (1) | BR0214469A (ko) |
CA (1) | CA2468412C (ko) |
CY (1) | CY1108279T1 (ko) |
DE (2) | DE10159217A1 (ko) |
DK (1) | DK1448591T3 (ko) |
ES (1) | ES2307819T3 (ko) |
HK (2) | HK1077832A1 (ko) |
IL (2) | IL162200A0 (ko) |
MX (1) | MXPA04005015A (ko) |
NO (2) | NO326241B1 (ko) |
PE (1) | PE20030727A1 (ko) |
PL (1) | PL207955B1 (ko) |
PT (1) | PT1448591E (ko) |
RU (2) | RU2339643C2 (ko) |
TW (1) | TWI256891B (ko) |
UY (1) | UY27552A1 (ko) |
WO (1) | WO2003045972A1 (ko) |
ZA (2) | ZA200405029B (ko) |
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US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
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KR20190104039A (ko) | 2017-01-03 | 2019-09-05 | 인타르시아 세라퓨틱스 인코포레이티드 | Glp-1 수용체 효능제의 연속적인 투여 및 약물의 동시-투여를 포함하는 방법 |
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RU2750488C1 (ru) * | 2020-06-03 | 2021-06-28 | Федеральное государственное бюджетное учреждение науки Новосибирский институт органической химии им. Н.Н. Ворожцова Сибирского отделения Российской академии наук (НИОХ СО РАН) | 1,2,4-Оксадиазольные производные дезоксихолевой кислоты, обладающие простатопротекторным действием, гипохолестеринемической и противовоспалительной активностями |
CN116535454A (zh) * | 2023-04-28 | 2023-08-04 | 香港中文大学(深圳) | 氟维司群类化合物及其制备方法和应用 |
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IL36654A (en) | 1970-04-24 | 1974-07-31 | Ciba Geigy Ag | 3-cyclopentyl ethers of 7alpha-methyl-3,16alpha,17(alpha and beta)-trihydroxy-delta 1,3,5(10)-estratriene,their manufacture and estrogenic pharmaceutical compositions containing them |
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DE19635525A1 (de) * | 1996-08-20 | 1998-02-26 | Schering Ag | 7alpha-(xi-Aminoalkyl)-estratriene, Verfahren zu deren Herstellung, pharmazeutische Präparate, die diese 7alpha(xi-Aminoalkyl-estratriene enthalten sowie deren Verwendung zur Herstellung von Arzneimitteln |
US5866560A (en) | 1996-08-20 | 1999-02-02 | Schering Ag | 7α-(ξ-aminoalkyl)-estratrienes, process for their production, pharmaceutical preparations which contain these 7α-(ξ-aminoalkyl)-estratrienes as well as their use for the production of pharmaceutical agents |
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DE19706061A1 (de) | 1997-02-07 | 1998-08-13 | Schering Ag | Antigestagen wirksame Steroide mit fluorierter 17alpha-Alkylkette |
PE20000129A1 (es) * | 1997-12-23 | 2000-03-11 | Schering Ag | 11 beta-halogeno-estratrienos sustituidos en 7 alfa, asi como el procedimiento para elaborar preparados farmaceuticos que contienen tales 11 beta-halogeno-estratrienos sustituidos en 7 alfa |
DE19807791A1 (de) * | 1998-02-19 | 1999-08-26 | Schering Ag | Kombinationspräparat aus Östrogen und Antiöstrogen |
DE10019171A1 (de) | 2000-04-07 | 2001-10-18 | Schering Ag | Zusammensetzungen zur Verwendung als Penetrationsverstärker in transdermalen Formulierungen für hoch lipophile Wirkstoffe |
WO2002032430A1 (en) | 2000-10-18 | 2002-04-25 | Schering Aktiengesellschaft | Use of antiprogestins for prophylaxis and treatment of hormone-dependent diseases |
DE10159217A1 (de) | 2001-11-27 | 2003-06-05 | Schering Ag | 17alpha-Alkyl-17ß-oxy-estratriene und Zwischenprodukte zu deren Herstellung, Verwendung der 17alpha-Alkyl-17ß-oxy-estratriene zur Herstellung von Arzneimitteln sowie pharmazeutische Präparate |
US20040242551A1 (en) | 2003-05-28 | 2004-12-02 | Schering Ag | Composition comprising antiprogestins and pure antiestrogens for prophylaxis and treatment of hormone-dependent diseases |
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- 2002-11-27 EP EP08075102A patent/EP1916254A3/de not_active Withdrawn
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