DK1448591T3 - 17-alpha-alkyl-17-beta-oxy-estratriener og mellemprodukter til fremstilling heraf, anvendelse af 17-alpha-alkyl-17-beta-oxy-estratriener til fremstilling af lægemidler samt farmaceutiske præparater - Google Patents

17-alpha-alkyl-17-beta-oxy-estratriener og mellemprodukter til fremstilling heraf, anvendelse af 17-alpha-alkyl-17-beta-oxy-estratriener til fremstilling af lægemidler samt farmaceutiske præparater

Info

Publication number
DK1448591T3
DK1448591T3 DK02795080T DK02795080T DK1448591T3 DK 1448591 T3 DK1448591 T3 DK 1448591T3 DK 02795080 T DK02795080 T DK 02795080T DK 02795080 T DK02795080 T DK 02795080T DK 1448591 T3 DK1448591 T3 DK 1448591T3
Authority
DK
Denmark
Prior art keywords
estratrienes
oxy
beta
alpha
alkyl
Prior art date
Application number
DK02795080T
Other languages
Danish (da)
English (en)
Inventor
Rolf Bohlmann
Nikolaus Heinrich
Rolf Jautelat
Jorg Kroll
Orlin Petrov
Andreas Reichel
Jens Hoffmann
Rosemarie Lichtner
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Application granted granted Critical
Publication of DK1448591T3 publication Critical patent/DK1448591T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16Masculine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32Antioestrogens
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0072Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK02795080T 2001-11-27 2002-11-27 17-alpha-alkyl-17-beta-oxy-estratriener og mellemprodukter til fremstilling heraf, anvendelse af 17-alpha-alkyl-17-beta-oxy-estratriener til fremstilling af lægemidler samt farmaceutiske præparater DK1448591T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10159217A DE10159217A1 (de) 2001-11-27 2001-11-27 17alpha-Alkyl-17ß-oxy-estratriene und Zwischenprodukte zu deren Herstellung, Verwendung der 17alpha-Alkyl-17ß-oxy-estratriene zur Herstellung von Arzneimitteln sowie pharmazeutische Präparate
PCT/EP2002/013484 WO2003045972A1 (de) 2001-11-27 2002-11-27 17α-ALKYL-17β-OXY-ESTRATRIENE UND ZWISCHENPRODUKTE ZU DEREN HERSTELLUNG, VERWENDUNG DER 17α-ALKYL-17β-OXY-ESTRATRIENE ZUR HERSTELLUNG VON ARZNEIMITTELN SOWIE PHARMAZEUTISCHE PRÄPARATE

Publications (1)

Publication Number Publication Date
DK1448591T3 true DK1448591T3 (da) 2008-09-29

Family

ID=7707804

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02795080T DK1448591T3 (da) 2001-11-27 2002-11-27 17-alpha-alkyl-17-beta-oxy-estratriener og mellemprodukter til fremstilling heraf, anvendelse af 17-alpha-alkyl-17-beta-oxy-estratriener til fremstilling af lægemidler samt farmaceutiske præparater

Country Status (26)

Country Link
US (2) US7018994B2 (ko)
EP (2) EP1916254A3 (ko)
JP (3) JP2005513039A (ko)
KR (1) KR100956912B1 (ko)
CN (2) CN1325507C (ko)
AR (1) AR037674A1 (ko)
AT (1) ATE396198T1 (ko)
AU (1) AU2002360949A1 (ko)
BR (1) BR0214469A (ko)
CA (1) CA2468412C (ko)
CY (1) CY1108279T1 (ko)
DE (2) DE10159217A1 (ko)
DK (1) DK1448591T3 (ko)
ES (1) ES2307819T3 (ko)
HK (2) HK1077832A1 (ko)
IL (2) IL162200A0 (ko)
MX (1) MXPA04005015A (ko)
NO (2) NO326241B1 (ko)
PE (1) PE20030727A1 (ko)
PL (1) PL207955B1 (ko)
PT (1) PT1448591E (ko)
RU (2) RU2285009C2 (ko)
TW (1) TWI256891B (ko)
UY (1) UY27552A1 (ko)
WO (1) WO2003045972A1 (ko)
ZA (2) ZA200405029B (ko)

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DE102009034362A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034368A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-acyloxyalkylenphenyl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034366A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-methylenoxyalkylenaryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034525A1 (de) 2009-07-21 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
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Also Published As

Publication number Publication date
CN100558741C (zh) 2009-11-11
EP1916254A3 (de) 2012-11-14
US20030191099A1 (en) 2003-10-09
DE10159217A1 (de) 2003-06-05
US20060009436A1 (en) 2006-01-12
US7538100B2 (en) 2009-05-26
WO2003045972A1 (de) 2003-06-05
MXPA04005015A (es) 2005-04-08
IL162200A (en) 2010-06-30
DE50212302D1 (de) 2008-07-03
ATE396198T1 (de) 2008-06-15
KR100956912B1 (ko) 2010-05-11
JP4335820B2 (ja) 2009-09-30
RU2285009C2 (ru) 2006-10-10
US7018994B2 (en) 2006-03-28
TWI256891B (en) 2006-06-21
BR0214469A (pt) 2004-10-13
NO326241B1 (no) 2008-10-27
IL162200A0 (en) 2005-11-20
EP1448591A1 (de) 2004-08-25
CN1325507C (zh) 2007-07-11
JP2005513039A (ja) 2005-05-12
CY1108279T1 (el) 2014-02-12
CA2468412A1 (en) 2003-06-05
RU2339643C2 (ru) 2008-11-27
PT1448591E (pt) 2008-09-19
HK1079215A1 (en) 2006-03-31
ZA200407868B (en) 2005-04-26
HK1077832A1 (en) 2006-02-24
NO20042694L (no) 2004-07-22
RU2004119437A (ru) 2005-07-10
PL207955B1 (pl) 2011-02-28
KR20040063158A (ko) 2004-07-12
ES2307819T3 (es) 2008-12-01
CA2468412C (en) 2010-01-12
PE20030727A1 (es) 2003-09-18
UY27552A1 (es) 2003-06-30
JP2005120110A (ja) 2005-05-12
AR037674A1 (es) 2004-12-01
AU2002360949A1 (en) 2003-06-10
RU2006120215A (ru) 2008-01-10
EP1916254A2 (de) 2008-04-30
JP2006306896A (ja) 2006-11-09
ZA200405029B (en) 2009-07-29
EP1448591B1 (de) 2008-05-21
PL369171A1 (en) 2005-04-18
CN1637015A (zh) 2005-07-13
CN1617879A (zh) 2005-05-18
TW200305426A (en) 2003-11-01
NO20044192L (no) 2004-10-04

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