NO316662B1 - Intrabukkalt opploselig, presstopt produkter og fremgangsmate for fremstilling dette - Google Patents

Intrabukkalt opploselig, presstopt produkter og fremgangsmate for fremstilling dette Download PDF

Info

Publication number
NO316662B1
NO316662B1 NO19963180A NO963180A NO316662B1 NO 316662 B1 NO316662 B1 NO 316662B1 NO 19963180 A NO19963180 A NO 19963180A NO 963180 A NO963180 A NO 963180A NO 316662 B1 NO316662 B1 NO 316662B1
Authority
NO
Norway
Prior art keywords
saccharide
castability
hardness
low
pressure
Prior art date
Application number
NO19963180A
Other languages
English (en)
Norwegian (no)
Other versions
NO963180L (no
NO963180D0 (no
Inventor
Muneo Fukui
Takao Mizumoto
Yoshinori Masuda
Original Assignee
Yamanouchi Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharma Co Ltd filed Critical Yamanouchi Pharma Co Ltd
Publication of NO963180D0 publication Critical patent/NO963180D0/no
Publication of NO963180L publication Critical patent/NO963180L/no
Publication of NO316662B1 publication Critical patent/NO316662B1/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Detergent Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Dental Preparations (AREA)
NO19963180A 1994-01-31 1996-07-30 Intrabukkalt opploselig, presstopt produkter og fremgangsmate for fremstilling dette NO316662B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP1011294 1994-01-31
JP8665294 1994-04-25
PCT/JP1995/000102 WO1995020380A1 (fr) 1994-01-31 1995-01-27 Moulage comprime a solubilite intra-orale et son procede de production

Publications (3)

Publication Number Publication Date
NO963180D0 NO963180D0 (no) 1996-07-30
NO963180L NO963180L (no) 1996-09-30
NO316662B1 true NO316662B1 (no) 2004-03-22

Family

ID=26345308

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19963180A NO316662B1 (no) 1994-01-31 1996-07-30 Intrabukkalt opploselig, presstopt produkter og fremgangsmate for fremstilling dette

Country Status (21)

Country Link
EP (1) EP0745382B1 (zh)
JP (1) JP3122141B2 (zh)
KR (1) KR100386391B1 (zh)
CN (1) CN1182838C (zh)
AT (1) ATE253899T1 (zh)
AU (1) AU699715B2 (zh)
CA (1) CA2179382C (zh)
DE (1) DE69532110T2 (zh)
DK (1) DK0745382T3 (zh)
ES (1) ES2210280T3 (zh)
FI (1) FI120817B (zh)
HU (1) HUT74908A (zh)
MX (1) MX9603035A (zh)
NO (1) NO316662B1 (zh)
NZ (1) NZ278678A (zh)
PH (1) PH31467A (zh)
PL (1) PL187160B1 (zh)
PT (1) PT745382E (zh)
RU (1) RU2147227C1 (zh)
TW (1) TW391880B (zh)
WO (1) WO1995020380A1 (zh)

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TW580397B (en) 1997-05-27 2004-03-21 Takeda Chemical Industries Ltd Solid preparation
FR2766089B1 (fr) * 1997-07-21 2000-06-02 Prographarm Lab Comprime multiparticulaire perfectionne a delitement rapide
US6465009B1 (en) 1998-03-18 2002-10-15 Yamanouchi Pharmaceutical Co., Ltd. Water soluble polymer-based rapidly dissolving tablets and production processes thereof
US6328994B1 (en) 1998-05-18 2001-12-11 Takeda Chemical Industries, Ltd. Orally disintegrable tablets
WO2000003735A1 (fr) 1998-07-15 2000-01-27 Asahi Kasei Kogyo Kabushiki Kaisha Excipient
EP1561458B1 (en) 1998-07-28 2010-09-15 Takeda Pharmaceutical Company Limited Rapidly disintegrable solid preparation
FR2785538B1 (fr) * 1998-11-06 2004-04-09 Prographarm Laboratoires Comprime a delitement rapide perfectionne
DE60020680T2 (de) * 1999-02-17 2006-05-04 Kyowa Hakko Kogyo Co., Ltd. Tabletten und verfahren zur tablettenherstellung
FR2790387B1 (fr) * 1999-03-01 2001-05-18 Prographarm Laboratoires Comprime orodispersible presentant une faible friabilite et son procede de preparation
GB9910505D0 (en) * 1999-05-06 1999-07-07 Electrosols Ltd A method and apparatus for manufacturing consumable tablets
US6656492B2 (en) 2000-06-30 2003-12-02 Yamanouchi Pharmaceutical Co., Ltd. Quick disintegrating tablet in buccal cavity and manufacturing method thereof
JP3415835B2 (ja) * 2000-06-30 2003-06-09 山之内製薬株式会社 口腔内速崩壊錠およびその製造法
CN1638739A (zh) * 2000-08-18 2005-07-13 法玛西雅厄普约翰美国公司 治疗成瘾性障碍的化合物
JP2002087965A (ja) * 2000-09-14 2002-03-27 Lion Corp 口中崩壊性アスピリン含有錠剤
CN100335040C (zh) * 2000-12-07 2007-09-05 奥坦纳医药公司 含有酸敏感型活性成分的快速崩解片剂
US6998139B2 (en) * 2001-03-15 2006-02-14 Astellas Pharma Inc. Bitterness-reduced intrabuccally quick disintegrating tablets and method for reducing bitterness
US6872405B2 (en) 2001-05-10 2005-03-29 Yamanouchi Pharmaceutical Co., Ltd. Quick-disintegrating tablet in buccal cavity and manufacturing method thereof
US7255876B2 (en) * 2001-07-27 2007-08-14 Astellas Pharma, Inc. Composition comprises sustained-release fine particles and manufacturing method thereof
CN1284532C (zh) * 2001-09-28 2006-11-15 株式会社三和化学研究所 有核型速溶崩解性成型品
FR2831820B1 (fr) * 2001-11-05 2004-08-20 Ethypharm Sa Comprime orodispersible presentant une grande homogeneite et son procede de preparation
EP1446088A2 (en) * 2001-11-07 2004-08-18 Pharmacia Corporation Intraorally disintegrating valdecoxib compositions prepared by fluid bed granulation process
FR2834894B1 (fr) * 2002-01-21 2004-02-27 Servier Lab Composition pharmaceutique orodispersible de piribedil
FR2834897B1 (fr) * 2002-01-23 2004-02-27 Servier Lab Composition pharmaceutique orodispersible de testosterone
FR2834896B1 (fr) * 2002-01-23 2004-02-27 Servier Lab Composition pharmaceutique orodispersible d'ivabradine
FR2834890B1 (fr) * 2002-01-23 2004-02-27 Servier Lab Composition pharmaceutique orodispersible d'agomelatine
FR2834891B1 (fr) * 2002-01-23 2004-02-27 Servier Lab Composition pharmaceutique orodispersible de 2-({2-methoxy-2-[3(trifluoromethyl)phenyl]ethyl}amino)ethyl4 -(2-(9h-fluoren-9-yl)acetyl]amino}ethyl)benzoate
FR2834892B1 (fr) * 2002-01-23 2004-02-27 Servier Lab Composition pharmaceutique orodispersible de mitiglinide
FR2834893B1 (fr) * 2002-01-23 2004-02-27 Servier Lab Composition pharmaceutique orodispersible de perindopril
AU2003259336A1 (en) * 2002-08-21 2004-03-11 Phoqus Pharmaceuticals Limited Use of an aqueous solution of citric acid and a water-soluble sugar like lactitol as granulation liquid in the manufacture of tablets
JPWO2004066991A1 (ja) * 2003-01-27 2006-05-18 アステラス製薬株式会社 タムスロシンまたはその塩の腸溶性徐放微粒子およびその製造法
US7749533B2 (en) * 2003-05-07 2010-07-06 Akina, Inc. Highly plastic granules for making fast melting tablets
US8349361B2 (en) 2003-10-15 2013-01-08 Fuji Chemical Industry Co., Ltd. Composition for rapid disintegrating tablet in oral cavity
JP3841804B2 (ja) 2003-10-15 2006-11-08 富士化学工業株式会社 口腔内速崩壊性錠剤用の組成物
US8647668B2 (en) 2003-10-15 2014-02-11 Fuji Chemical Industry Co., Ltd. Tablet quickly disintegrating in oral cavity
US7670624B2 (en) 2004-01-29 2010-03-02 Astella Pharma Inc. Gastrointestinal-specific multiple drug release system
WO2005102287A2 (en) 2004-04-22 2005-11-03 Duocort Ab Pharmaceutical compositions for acute glucocorticoid therapy
SE0401031D0 (sv) 2004-04-22 2004-04-22 Duocort Ab A new glucocorticoid replacement therapy
US7723306B2 (en) 2004-05-10 2010-05-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Spray-dried powder comprising at least one 1,4 O-linked saccharose-derivative and methods for their preparation
US7727962B2 (en) 2004-05-10 2010-06-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Powder comprising new compositions of oligosaccharides and methods for their preparation
DE102004022928A1 (de) * 2004-05-10 2005-12-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulver enthaltend neuartige Oligosacharidgemische und Verfahren zu deren Herstellung
DE102004022926A1 (de) * 2004-05-10 2005-12-15 Boehringer Ingelheim Pharma Gmbh & Co. Kg Sprühgetrocknete Pulver enthaltend zumindest ein 1,4 O-verknüpftes Saccharose-Derivat und Verfahren zu deren Herstellung
US7611709B2 (en) 2004-05-10 2009-11-03 Boehringer Ingelheim Pharma Gmbh And Co. Kg 1,4 O-linked saccharose derivatives for stabilization of antibodies or antibody derivatives
TWI354559B (en) * 2004-12-27 2011-12-21 Yaizu Suisankagaku Ind Co Ltd Oral disintegrative n-acetylglucosamine tablet and
JP5014115B2 (ja) * 2005-01-31 2012-08-29 協和発酵バイオ株式会社 オルニチン塩酸塩を含有する錠剤
JP5004236B2 (ja) * 2005-02-09 2012-08-22 キッセイ薬品工業株式会社 口腔内崩壊錠
CN1839847B (zh) * 2005-03-31 2012-07-11 成都科瑞德医药投资有限责任公司 盐酸替扎尼定口腔崩解片及其制备方法
US20090306227A1 (en) * 2005-08-31 2009-12-10 Toshiyuki Ioka Tablet for removing tongue coating
CN101420982B (zh) * 2006-04-13 2011-11-09 东亚药品株式会社 干式直压速崩片
WO2008032767A1 (fr) 2006-09-14 2008-03-20 Astellas Pharma Inc. Comprimé se désintegrant oralement et procédé de fabrication de celui-ci
JPWO2008081829A1 (ja) 2006-12-27 2010-04-30 アステラス製薬株式会社 難水溶性薬物の溶解性維持用アミノアルキルメタアクリレートコポリマーe
WO2009084678A1 (ja) * 2007-12-28 2009-07-09 Sawai Pharmaceutical Co., Ltd. 口腔内崩壊錠およびその製造方法
JP5515074B2 (ja) * 2008-12-08 2014-06-11 杏林製薬株式会社 口腔内速崩壊性錠剤
TWI429401B (zh) 2010-06-13 2014-03-11 Meiji Co Ltd 固形乳及其製造方法
WO2012029838A1 (ja) 2010-08-31 2012-03-08 協和発酵キリン株式会社 口腔内崩壊錠
MX2014007933A (es) 2011-12-26 2014-07-30 Novartis Ag Comprimidos y agentes recubiertos en seco.
WO2013125350A1 (ja) * 2012-02-23 2013-08-29 フロイント産業株式会社 口腔内崩壊錠用直打賦形剤及びその製造方法、並びに口腔内崩壊錠
TWI612975B (zh) 2012-03-02 2018-02-01 安斯泰來製藥股份有限公司 速崩散性錠劑
ES2694224T3 (es) * 2012-04-24 2018-12-19 Daiichi Sankyo Company, Limited Comprimido de desintegración oral y procedimiento para producir el mismo
CN102784117A (zh) * 2012-08-23 2012-11-21 海南卫康制药(潜山)有限公司 硫酸庆大霉素组合物冻干口腔崩解片及其制备方法
KR101352689B1 (ko) * 2012-12-31 2014-01-17 (주) 에프엔지리서치 불연속상과 연속상으로 이루어지는 응집단위를 포함하는 마이크로그래뉼 제형
EP2952187A4 (en) * 2013-01-30 2016-08-17 Sawai Seiyaku Kk PHARMACEUTICAL COMPOSITION WITH CANDESARTAN CILEXETIL
CN103202817B (zh) * 2013-04-28 2014-10-08 山东天力药业有限公司 一种可直压性甘露醇颗粒的制备方法
WO2017217494A1 (ja) 2016-06-16 2017-12-21 東和薬品株式会社 口腔内崩壊錠
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Also Published As

Publication number Publication date
EP0745382A1 (en) 1996-12-04
ES2210280T3 (es) 2004-07-01
HUT74908A (en) 1997-03-28
DE69532110T2 (de) 2004-09-09
CN1139878A (zh) 1997-01-08
PL315552A1 (en) 1996-11-12
CN1182838C (zh) 2005-01-05
NZ278678A (en) 1998-03-25
EP0745382B1 (en) 2003-11-12
HU9602083D0 (en) 1996-09-30
EP0745382A4 (en) 1997-10-29
TW391880B (en) 2000-06-01
MX9603035A (es) 1997-05-31
CA2179382C (en) 2009-11-10
NO963180L (no) 1996-09-30
PT745382E (pt) 2004-04-30
AU1467195A (en) 1995-08-15
FI963022A (fi) 1996-07-31
DE69532110D1 (de) 2003-12-18
RU2147227C1 (ru) 2000-04-10
FI120817B (fi) 2010-03-31
KR100386391B1 (ko) 2003-08-30
DK0745382T3 (da) 2004-03-22
PL187160B1 (pl) 2004-05-31
JP3122141B2 (ja) 2001-01-09
FI963022A0 (fi) 1996-07-31
WO1995020380A1 (fr) 1995-08-03
ATE253899T1 (de) 2003-11-15
AU699715B2 (en) 1998-12-10
NO963180D0 (no) 1996-07-30
PH31467A (en) 1998-11-03
CA2179382A1 (en) 1995-08-03

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