NO316256B1 - Anvendelse av 1-(2-naft-2-yletyl)-4-(3-trifluormetylfenyl)- 1,2,3,6-tetrahydropyridin for fremstilling av legemidler for behandling avamyotrof lateral sklerose - Google Patents
Anvendelse av 1-(2-naft-2-yletyl)-4-(3-trifluormetylfenyl)- 1,2,3,6-tetrahydropyridin for fremstilling av legemidler for behandling avamyotrof lateral sklerose Download PDFInfo
- Publication number
- NO316256B1 NO316256B1 NO19981856A NO981856A NO316256B1 NO 316256 B1 NO316256 B1 NO 316256B1 NO 19981856 A NO19981856 A NO 19981856A NO 981856 A NO981856 A NO 981856A NO 316256 B1 NO316256 B1 NO 316256B1
- Authority
- NO
- Norway
- Prior art keywords
- naphth
- ylethyl
- pharmaceutically acceptable
- treatment
- trifluoromethylphenyl
- Prior art date
Links
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9512635A FR2740343B1 (fr) | 1995-10-26 | 1995-10-26 | Utilisation de la 1-(2-napht-2-yl-ethyl)-4- (3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de la sclerose laterale amyotrophique |
| FR9607336 | 1996-06-13 | ||
| PCT/FR1996/001674 WO1997015304A1 (fr) | 1995-10-26 | 1996-10-25 | Utilisation de la 1-(2-napht-2-ylethyl)-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de la sclerose laterale amyotrophique |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO981856D0 NO981856D0 (no) | 1998-04-24 |
| NO981856L NO981856L (no) | 1998-06-11 |
| NO316256B1 true NO316256B1 (no) | 2004-01-05 |
Family
ID=26232287
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19981856A NO316256B1 (no) | 1995-10-26 | 1998-04-24 | Anvendelse av 1-(2-naft-2-yletyl)-4-(3-trifluormetylfenyl)- 1,2,3,6-tetrahydropyridin for fremstilling av legemidler for behandling avamyotrof lateral sklerose |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US6043251A (ja) |
| EP (1) | EP0866704B1 (ja) |
| JP (1) | JP3468526B2 (ja) |
| KR (1) | KR100472793B1 (ja) |
| CN (1) | CN1104241C (ja) |
| AT (1) | ATE200423T1 (ja) |
| AU (1) | AU719342B2 (ja) |
| BR (1) | BR9611124A (ja) |
| CA (1) | CA2235747C (ja) |
| CY (1) | CY2279B1 (ja) |
| CZ (1) | CZ293360B6 (ja) |
| DE (1) | DE69612510T2 (ja) |
| DK (1) | DK0866704T3 (ja) |
| EE (1) | EE04177B1 (ja) |
| ES (1) | ES2159362T3 (ja) |
| GR (1) | GR3036027T3 (ja) |
| HK (1) | HK1016904A1 (ja) |
| HU (1) | HU222039B1 (ja) |
| IL (1) | IL124091A (ja) |
| IS (1) | IS1961B (ja) |
| NO (1) | NO316256B1 (ja) |
| NZ (1) | NZ320355A (ja) |
| PT (1) | PT866704E (ja) |
| SI (1) | SI0866704T1 (ja) |
| SK (1) | SK284099B6 (ja) |
| TR (1) | TR199800717T2 (ja) |
| UA (1) | UA57004C2 (ja) |
| WO (1) | WO1997015304A1 (ja) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2782008B1 (fr) * | 1998-08-07 | 2003-04-25 | Sod Conseils Rech Applic | Utilisation d'extraits de ginkgo biloba pour preparer un medicament destine a traiter la sclerose laterale amyotrophique |
| US20060281797A1 (en) * | 2001-12-11 | 2006-12-14 | University Of Virginia Patent Foundation | Neurorestoration with R(+) Pramipexole |
| AU2002360600B2 (en) * | 2001-12-11 | 2007-11-29 | University Of Virginia Patent Foundation | Use of pramipexole to treat amyotrophic lateral sclerosis |
| KR101130212B1 (ko) * | 2002-03-27 | 2012-04-13 | 파이토팜 피엘씨 | 사포게닌 및 그 유도체의 치료 방법 및 사용법 |
| JP2009504748A (ja) * | 2005-08-15 | 2009-02-05 | ユニバーシティ オブ バージニア パテント ファウンデーション | Ｒ（＋）プラミペキソールを用いた神経回復 |
| US8518926B2 (en) | 2006-04-10 | 2013-08-27 | Knopp Neurosciences, Inc. | Compositions and methods of using (R)-pramipexole |
| CN101448498B (zh) | 2006-05-16 | 2011-04-27 | 诺普神经科学股份有限公司 | R(+)和s(-)普拉克索的组合物以及使用该组合物的方法 |
| US8524695B2 (en) | 2006-12-14 | 2013-09-03 | Knopp Neurosciences, Inc. | Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same |
| US8519148B2 (en) | 2007-03-14 | 2013-08-27 | Knopp Neurosciences, Inc. | Synthesis of chirally purified substituted benzothiazole diamines |
| WO2010022140A1 (en) * | 2008-08-19 | 2010-02-25 | Knopp Neurosciences, Inc. | Compositions and methods of using (r)-pramipexole |
| WO2013096816A1 (en) | 2011-12-22 | 2013-06-27 | Biogen Idec Ma Inc. | Improved synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds |
| US9662313B2 (en) | 2013-02-28 | 2017-05-30 | Knopp Biosciences Llc | Compositions and methods for treating amyotrophic lateral sclerosis in responders |
| LT3019167T (lt) | 2013-07-12 | 2021-03-25 | Knopp Biosciences Llc | Eozinofilų ir (arba) bazofilų padidintų kiekių gydymas |
| US9468630B2 (en) | 2013-07-12 | 2016-10-18 | Knopp Biosciences Llc | Compositions and methods for treating conditions related to increased eosinophils |
| CA2921381A1 (en) | 2013-08-13 | 2015-02-19 | Knopp Biosciences Llc | Compositions and methods for treating chronic urticaria |
| EP3038467B1 (en) | 2013-08-13 | 2020-07-29 | Knopp Biosciences LLC | Compositions and methods for treating plasma cell disorders and b-cell prolymphocytic disorders |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2662355B1 (fr) * | 1990-05-22 | 1994-11-10 | Sanofi Sa | Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux. |
| FR2672213B1 (fr) * | 1991-02-05 | 1995-03-10 | Sanofi Sa | Utilisation de derives 4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridiniques comme capteurs de radicaux libres. |
| FR2672731A1 (fr) * | 1991-02-07 | 1992-08-14 | France Telecom | Procede d'oxydation localisee enterree d'un substrat de silicium et circuit integre correspondant. |
| FR2688138B1 (fr) * | 1992-03-06 | 1995-05-05 | Rhone Poulenc Rorer Sa | Application de l'amino-2 trifluoromethoxy-6 benzothiazole pour obtenir un medicament destine au traitement de la sclerose laterale amyotrophique. |
-
1996
- 1996-10-25 EP EP96934975A patent/EP0866704B1/fr not_active Expired - Lifetime
- 1996-10-25 BR BR9611124A patent/BR9611124A/pt not_active Application Discontinuation
- 1996-10-25 KR KR10-1998-0702997A patent/KR100472793B1/ko not_active IP Right Cessation
- 1996-10-25 HU HU9802945A patent/HU222039B1/hu not_active IP Right Cessation
- 1996-10-25 AT AT96934975T patent/ATE200423T1/de not_active IP Right Cessation
- 1996-10-25 AU AU73084/96A patent/AU719342B2/en not_active Ceased
- 1996-10-25 EE EE9800132A patent/EE04177B1/xx not_active IP Right Cessation
- 1996-10-25 IL IL12409196A patent/IL124091A/xx not_active IP Right Cessation
- 1996-10-25 TR TR1998/00717T patent/TR199800717T2/xx unknown
- 1996-10-25 CZ CZ19981296A patent/CZ293360B6/cs not_active IP Right Cessation
- 1996-10-25 UA UA98042073A patent/UA57004C2/uk unknown
- 1996-10-25 PT PT96934975T patent/PT866704E/pt unknown
- 1996-10-25 US US09/051,740 patent/US6043251A/en not_active Expired - Fee Related
- 1996-10-25 WO PCT/FR1996/001674 patent/WO1997015304A1/fr active IP Right Grant
- 1996-10-25 JP JP51637097A patent/JP3468526B2/ja not_active Expired - Fee Related
- 1996-10-25 CN CN96198508A patent/CN1104241C/zh not_active Expired - Fee Related
- 1996-10-25 DE DE69612510T patent/DE69612510T2/de not_active Expired - Fee Related
- 1996-10-25 ES ES96934975T patent/ES2159362T3/es not_active Expired - Lifetime
- 1996-10-25 CA CA002235747A patent/CA2235747C/en not_active Expired - Fee Related
- 1996-10-25 SI SI9630299T patent/SI0866704T1/xx unknown
- 1996-10-25 DK DK96934975T patent/DK0866704T3/da active
- 1996-10-25 SK SK526-98A patent/SK284099B6/sk unknown
- 1996-10-25 NZ NZ320355A patent/NZ320355A/xx unknown
-
1998
- 1998-04-21 IS IS4722A patent/IS1961B/is unknown
- 1998-04-24 NO NO19981856A patent/NO316256B1/no unknown
-
1999
- 1999-05-24 HK HK99102262A patent/HK1016904A1/xx not_active IP Right Cessation
-
2001
- 2001-06-13 GR GR20010400880T patent/GR3036027T3/el not_active IP Right Cessation
-
2002
- 2002-05-15 CY CY0200033A patent/CY2279B1/xx unknown
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