NO315308B1 - Granulert produkt eller tablett inneholdende et brusende system og en aktivfarmasoytisk substans, samt fremgangsmater til fremstilling derav - Google Patents
Granulert produkt eller tablett inneholdende et brusende system og en aktivfarmasoytisk substans, samt fremgangsmater til fremstilling derav Download PDFInfo
- Publication number
- NO315308B1 NO315308B1 NO19963588A NO963588A NO315308B1 NO 315308 B1 NO315308 B1 NO 315308B1 NO 19963588 A NO19963588 A NO 19963588A NO 963588 A NO963588 A NO 963588A NO 315308 B1 NO315308 B1 NO 315308B1
- Authority
- NO
- Norway
- Prior art keywords
- weight
- acid
- effervescent
- carbonate
- tablet
- Prior art date
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- 239000003814 drug Substances 0.000 title claims description 24
- 238000000034 method Methods 0.000 title claims description 20
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 133
- 239000002253 acid Substances 0.000 claims description 77
- 239000003826 tablet Substances 0.000 claims description 66
- 239000000126 substance Substances 0.000 claims description 65
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 claims description 50
- 239000000047 product Substances 0.000 claims description 47
- 239000000203 mixture Substances 0.000 claims description 46
- 230000007935 neutral effect Effects 0.000 claims description 43
- 239000000243 solution Substances 0.000 claims description 41
- 239000008187 granular material Substances 0.000 claims description 39
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 38
- 239000013543 active substance Substances 0.000 claims description 35
- 239000013078 crystal Substances 0.000 claims description 34
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 32
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims description 32
- 238000000576 coating method Methods 0.000 claims description 31
- 239000011248 coating agent Substances 0.000 claims description 30
- 239000007938 effervescent tablet Substances 0.000 claims description 29
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 claims description 28
- 238000004090 dissolution Methods 0.000 claims description 28
- 150000007524 organic acids Chemical class 0.000 claims description 28
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims description 27
- 238000006243 chemical reaction Methods 0.000 claims description 27
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 26
- 239000000600 sorbitol Substances 0.000 claims description 26
- 235000010356 sorbitol Nutrition 0.000 claims description 26
- 229910000029 sodium carbonate Inorganic materials 0.000 claims description 24
- 239000007787 solid Substances 0.000 claims description 23
- 229960001380 cimetidine Drugs 0.000 claims description 20
- CCGSUNCLSOWKJO-UHFFFAOYSA-N cimetidine Chemical compound N#CNC(=N/C)\NCCSCC1=NC=N[C]1C CCGSUNCLSOWKJO-UHFFFAOYSA-N 0.000 claims description 20
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims description 19
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- 239000003513 alkali Substances 0.000 claims description 19
- 229960005132 cisapride Drugs 0.000 claims description 19
- DCSUBABJRXZOMT-IRLDBZIGSA-N cisapride Chemical compound C([C@@H]([C@@H](CC1)NC(=O)C=2C(=CC(N)=C(Cl)C=2)OC)OC)N1CCCOC1=CC=C(F)C=C1 DCSUBABJRXZOMT-IRLDBZIGSA-N 0.000 claims description 19
- DCSUBABJRXZOMT-UHFFFAOYSA-N cisapride Natural products C1CC(NC(=O)C=2C(=CC(N)=C(Cl)C=2)OC)C(OC)CN1CCCOC1=CC=C(F)C=C1 DCSUBABJRXZOMT-UHFFFAOYSA-N 0.000 claims description 19
- 239000000594 mannitol Substances 0.000 claims description 19
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- 238000002156 mixing Methods 0.000 claims description 19
- 238000004519 manufacturing process Methods 0.000 claims description 17
- 229910000030 sodium bicarbonate Inorganic materials 0.000 claims description 16
- 235000017557 sodium bicarbonate Nutrition 0.000 claims description 16
- 238000001035 drying Methods 0.000 claims description 15
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- 239000002245 particle Substances 0.000 claims description 15
- 238000007792 addition Methods 0.000 claims description 14
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- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims description 13
- 239000002518 antifoaming agent Substances 0.000 claims description 13
- AMTWCFIAVKBGOD-UHFFFAOYSA-N dioxosilane;methoxy-dimethyl-trimethylsilyloxysilane Chemical compound O=[Si]=O.CO[Si](C)(C)O[Si](C)(C)C AMTWCFIAVKBGOD-UHFFFAOYSA-N 0.000 claims description 11
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- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims description 10
- 230000002209 hydrophobic effect Effects 0.000 claims description 10
- HWPKGOGLCKPRLZ-UHFFFAOYSA-M monosodium citrate Chemical compound [Na+].OC(=O)CC(O)(C([O-])=O)CC(O)=O HWPKGOGLCKPRLZ-UHFFFAOYSA-M 0.000 claims description 10
- 235000018342 monosodium citrate Nutrition 0.000 claims description 10
- 239000002524 monosodium citrate Substances 0.000 claims description 10
- OENHQHLEOONYIE-UKMVMLAPSA-N all-trans beta-carotene Natural products CC=1CCCC(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C OENHQHLEOONYIE-UKMVMLAPSA-N 0.000 claims description 9
- 239000011648 beta-carotene Substances 0.000 claims description 9
- TUPZEYHYWIEDIH-WAIFQNFQSA-N beta-carotene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2=CCCCC2(C)C TUPZEYHYWIEDIH-WAIFQNFQSA-N 0.000 claims description 9
- 235000013734 beta-carotene Nutrition 0.000 claims description 9
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- 239000001267 polyvinylpyrrolidone Substances 0.000 claims description 9
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- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims description 9
- OENHQHLEOONYIE-JLTXGRSLSA-N β-Carotene Chemical compound CC=1CCCC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-JLTXGRSLSA-N 0.000 claims description 9
- 239000013530 defoamer Substances 0.000 claims description 8
- 235000003599 food sweetener Nutrition 0.000 claims description 8
- 239000004094 surface-active agent Substances 0.000 claims description 8
- 239000003765 sweetening agent Substances 0.000 claims description 8
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- 238000002844 melting Methods 0.000 claims description 7
- 230000008018 melting Effects 0.000 claims description 7
- 229960000620 ranitidine Drugs 0.000 claims description 7
- VMXUWOKSQNHOCA-LCYFTJDESA-N ranitidine Chemical compound [O-][N+](=O)/C=C(/NC)NCCSCC1=CC=C(CN(C)C)O1 VMXUWOKSQNHOCA-LCYFTJDESA-N 0.000 claims description 7
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 claims description 6
- 239000007864 aqueous solution Substances 0.000 claims description 6
- 150000001720 carbohydrates Chemical class 0.000 claims description 6
- 235000014633 carbohydrates Nutrition 0.000 claims description 6
- 239000000416 hydrocolloid Substances 0.000 claims description 6
- 239000002904 solvent Substances 0.000 claims description 6
- 239000000725 suspension Substances 0.000 claims description 6
- OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 claims description 5
- 150000001447 alkali salts Chemical class 0.000 claims description 5
- 229910000019 calcium carbonate Inorganic materials 0.000 claims description 5
- 229910002092 carbon dioxide Inorganic materials 0.000 claims description 5
- 238000002425 crystallisation Methods 0.000 claims description 5
- 230000008025 crystallization Effects 0.000 claims description 5
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 claims description 5
- 239000011976 maleic acid Substances 0.000 claims description 5
- 239000000843 powder Substances 0.000 claims description 5
- 229960001520 ranitidine hydrochloride Drugs 0.000 claims description 5
- GGWBHVILAJZWKJ-KJEVSKRMSA-N ranitidine hydrochloride Chemical compound [H+].[Cl-].[O-][N+](=O)\C=C(/NC)NCCSCC1=CC=C(CN(C)C)O1 GGWBHVILAJZWKJ-KJEVSKRMSA-N 0.000 claims description 5
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 claims description 5
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 4
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims description 4
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- 150000003839 salts Chemical class 0.000 claims description 4
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- ZAKOWWREFLAJOT-UHFFFAOYSA-N d-alpha-Tocopheryl acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-UHFFFAOYSA-N 0.000 claims description 3
- 239000004205 dimethyl polysiloxane Substances 0.000 claims description 3
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- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 2
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 claims description 2
- 150000001298 alcohols Chemical class 0.000 claims description 2
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- -1 alkali metal salt Chemical class 0.000 claims 5
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- 239000000375 suspending agent Substances 0.000 claims 4
- 229920003169 water-soluble polymer Polymers 0.000 claims 4
- CDOUZKKFHVEKRI-UHFFFAOYSA-N 3-bromo-n-[(prop-2-enoylamino)methyl]propanamide Chemical compound BrCCC(=O)NCNC(=O)C=C CDOUZKKFHVEKRI-UHFFFAOYSA-N 0.000 claims 2
- 150000001342 alkaline earth metals Chemical class 0.000 claims 2
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- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 claims 1
- 229940122957 Histamine H2 receptor antagonist Drugs 0.000 claims 1
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims 1
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- 229910000288 alkali metal carbonate Inorganic materials 0.000 claims 1
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- WXZMFSXDPGVJKK-UHFFFAOYSA-N pentaerythritol Chemical compound OCC(CO)(CO)CO WXZMFSXDPGVJKK-UHFFFAOYSA-N 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 229920006316 polyvinylpyrrolidine Polymers 0.000 description 1
- 239000000376 reactant Substances 0.000 description 1
- 230000009257 reactivity Effects 0.000 description 1
- 238000001953 recrystallisation Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 229940085605 saccharin sodium Drugs 0.000 description 1
- 235000019613 sensory perceptions of taste Nutrition 0.000 description 1
- 238000007873 sieving Methods 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 238000009492 tablet coating Methods 0.000 description 1
- 239000002700 tablet coating Substances 0.000 description 1
- 230000035923 taste sensation Effects 0.000 description 1
- 238000004448 titration Methods 0.000 description 1
- HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 description 1
- 229940038773 trisodium citrate Drugs 0.000 description 1
- 238000009827 uniform distribution Methods 0.000 description 1
- 238000009489 vacuum treatment Methods 0.000 description 1
- 238000003805 vibration mixing Methods 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 239000000811 xylitol Substances 0.000 description 1
- 235000010447 xylitol Nutrition 0.000 description 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
- 229960002675 xylitol Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4406641 | 1994-03-01 | ||
| CH87394 | 1994-03-23 | ||
| EP94203112A EP0670160B1 (en) | 1994-03-01 | 1994-10-26 | Granular product or tablet containing an effervescent system and an active pharmaceutical substance, as well as a method for its preparation |
| PCT/EP1995/000650 WO1995023594A1 (en) | 1994-03-01 | 1995-02-23 | Granular product or tablet containing an effervescent system and an active pharmaceutical substance, as well as a method for its preparation |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO963588D0 NO963588D0 (no) | 1996-08-28 |
| NO963588L NO963588L (no) | 1996-10-31 |
| NO315308B1 true NO315308B1 (no) | 2003-08-18 |
Family
ID=27172490
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19963588A NO315308B1 (no) | 1994-03-01 | 1996-08-28 | Granulert produkt eller tablett inneholdende et brusende system og en aktivfarmasoytisk substans, samt fremgangsmater til fremstilling derav |
Country Status (15)
| Country | Link |
|---|---|
| JP (1) | JPH09509669A (zh) |
| CN (1) | CN1213739C (zh) |
| AU (1) | AU681256B2 (zh) |
| BR (1) | BR9506964A (zh) |
| CA (1) | CA2183952C (zh) |
| CZ (1) | CZ291710B6 (zh) |
| DE (1) | DE670160T1 (zh) |
| FI (1) | FI118033B (zh) |
| HU (1) | HU228147B1 (zh) |
| NO (1) | NO315308B1 (zh) |
| NZ (1) | NZ281228A (zh) |
| PL (1) | PL181714B1 (zh) |
| RU (1) | RU2153331C2 (zh) |
| TW (1) | TW403658B (zh) |
| WO (1) | WO1995023594A1 (zh) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6489346B1 (en) | 1996-01-04 | 2002-12-03 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
| US5840737A (en) | 1996-01-04 | 1998-11-24 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
| US20030070584A1 (en) | 2001-05-15 | 2003-04-17 | Cynthia Gulian | Dip coating compositions containing cellulose ethers |
| US8309118B2 (en) | 2001-09-28 | 2012-11-13 | Mcneil-Ppc, Inc. | Film forming compositions containing sucralose |
| DE10224607B4 (de) * | 2002-06-04 | 2008-03-13 | Lts Lohmann Therapie-Systeme Ag | Filmförmige, zerfallsfähige Zubereitungen zur Wirkstofffreisetzung und Verfahren zu deren Herstellung |
| WO2004050068A1 (en) | 2002-11-29 | 2004-06-17 | Janssen Pharmaceutica N.V. | Pharmaceutical compositions comprising a basic respectively acidic drug compound, a surfactant and a physiologically tolerable water-soluble acid respectively base |
| US8993599B2 (en) | 2003-07-18 | 2015-03-31 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
| US8906940B2 (en) | 2004-05-25 | 2014-12-09 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
| US20080031942A1 (en) * | 2004-12-03 | 2008-02-07 | Takeda Pharmaceutical Company Limited | Solid Preparation |
| US8658208B2 (en) | 2010-02-26 | 2014-02-25 | Toray Industries, Inc. | Coated solid preparation |
| US9388053B2 (en) | 2011-12-09 | 2016-07-12 | Merck Patent Gmbh | Anhydrous sodium carbonate having a low pore content |
| WO2014065890A1 (en) * | 2012-10-25 | 2014-05-01 | Otc Nutrition Llc | Fast dissolving solid calcium mineral supplement compositions and process of making |
| AU2013361760B2 (en) * | 2012-12-19 | 2018-07-05 | Bayer Animal Health Gmbh | Tablets with improved acceptance and good storage stability |
| CN105670003A (zh) * | 2014-11-21 | 2016-06-15 | 常州坤宇环保科技有限公司 | 高吸水树脂防结块剂 |
| EP3318135A1 (en) * | 2016-11-03 | 2018-05-09 | Perfetti Van Melle S.p.A. | Effervescent candy material, a process for its preparation and products made therefrom |
| WO2021076506A1 (en) * | 2019-10-17 | 2021-04-22 | Isp Investments Llc | A stable effervescent co-processed excipient composition and a process for preparing the same |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU1039170A (en) * | 1969-02-24 | 1971-07-22 | Abbott Laboratories | Tableting medium |
| US4704269A (en) * | 1985-06-11 | 1987-11-03 | Hudson Pharmaceutical Corporation | Effervescent antacid and analgesic compositions |
| CA2023493C (en) * | 1989-08-31 | 2000-01-04 | Masami Moroi | Composition for foaming preparation |
| DK0592484T3 (da) * | 1991-07-01 | 1995-06-12 | Gerhard Gergely | Brusetablet |
-
1994
- 1994-10-26 DE DE0670160T patent/DE670160T1/de active Pending
-
1995
- 1995-02-23 RU RU96120083/14A patent/RU2153331C2/ru not_active IP Right Cessation
- 1995-02-23 WO PCT/EP1995/000650 patent/WO1995023594A1/en active IP Right Grant
- 1995-02-23 HU HU9602380A patent/HU228147B1/hu not_active IP Right Cessation
- 1995-02-23 JP JP7522671A patent/JPH09509669A/ja active Pending
- 1995-02-23 BR BR9506964A patent/BR9506964A/pt not_active Application Discontinuation
- 1995-02-23 CN CN95191882.6A patent/CN1213739C/zh not_active Expired - Fee Related
- 1995-02-23 NZ NZ281228A patent/NZ281228A/en unknown
- 1995-02-23 CZ CZ19962519A patent/CZ291710B6/cs not_active IP Right Cessation
- 1995-02-23 CA CA002183952A patent/CA2183952C/en not_active Expired - Fee Related
- 1995-02-23 AU AU18114/95A patent/AU681256B2/en not_active Ceased
- 1995-03-01 TW TW084101871A patent/TW403658B/zh not_active IP Right Cessation
-
1996
- 1996-08-22 PL PL95316113A patent/PL181714B1/pl unknown
- 1996-08-28 NO NO19963588A patent/NO315308B1/no not_active IP Right Cessation
- 1996-08-30 FI FI963385A patent/FI118033B/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2183952C (en) | 2007-01-16 |
| FI963385A0 (fi) | 1996-08-30 |
| PL316113A1 (en) | 1996-12-23 |
| NO963588L (no) | 1996-10-31 |
| NO963588D0 (no) | 1996-08-28 |
| WO1995023594A1 (en) | 1995-09-08 |
| RU2153331C2 (ru) | 2000-07-27 |
| HUT75677A (en) | 1997-05-28 |
| CN1213739C (zh) | 2005-08-10 |
| AU1811495A (en) | 1995-09-18 |
| CA2183952A1 (en) | 1995-09-08 |
| TW403658B (en) | 2000-09-01 |
| DE670160T1 (de) | 1996-03-14 |
| PL181714B1 (en) | 2001-09-28 |
| FI118033B (fi) | 2007-06-15 |
| CZ251996A3 (en) | 1997-01-15 |
| HU9602380D0 (en) | 1996-10-28 |
| FI963385A (fi) | 1996-10-30 |
| NZ281228A (en) | 1997-06-24 |
| BR9506964A (pt) | 1997-09-09 |
| JPH09509669A (ja) | 1997-09-30 |
| HU228147B1 (en) | 2012-12-28 |
| AU681256B2 (en) | 1997-08-21 |
| CN1142182A (zh) | 1997-02-05 |
| CZ291710B6 (cs) | 2003-05-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |