NO315198B1 - Fremgangsmåte for fremstilling av et oksazolyletanolderivat - Google Patents

Fremgangsmåte for fremstilling av et oksazolyletanolderivat Download PDF

Info

Publication number
NO315198B1
NO315198B1 NO20024058A NO20024058A NO315198B1 NO 315198 B1 NO315198 B1 NO 315198B1 NO 20024058 A NO20024058 A NO 20024058A NO 20024058 A NO20024058 A NO 20024058A NO 315198 B1 NO315198 B1 NO 315198B1
Authority
NO
Norway
Prior art keywords
preparation
possibly substituted
derivative
oxazolylethanol
formula
Prior art date
Application number
NO20024058A
Other languages
English (en)
Other versions
NO20024058D0 (no
NO20024058L (no
Inventor
Koji Ando
Masanobu Suzuki
Original Assignee
Japan Tobacco Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Publication of NO20024058L publication Critical patent/NO20024058L/no
Application filed by Japan Tobacco Inc filed Critical Japan Tobacco Inc
Publication of NO20024058D0 publication Critical patent/NO20024058D0/no
Publication of NO315198B1 publication Critical patent/NO315198B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Claims (1)

  1. Fremgangsmåte for fremstilling av et oksazolyletanolderivat av formelen [6] hvor R er en eventuell substituert aromatisk hydrokarbongruppe, en eventuell substituert alicyklisk hydrokarbongruppe, en eventuell substituert heterocyklisk gruppe eller en eventuell substituert kondensert heterocyklisk gruppe eller et salt herav, karakterisert ved at den omfatter å reagere et oksazolylacetatderivat av formelen [5] hvor R er som definert ovenfor, i tetrahydrofuran i nærvær av NaBrL; som et reduksjonsmiddel og metanol som et aktiveringsmiddel.
NO20024058A 1998-03-30 2002-08-26 Fremgangsmåte for fremstilling av et oksazolyletanolderivat NO315198B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10409898 1998-03-30
PCT/JP1999/001434 WO1999050267A1 (fr) 1998-03-30 1999-03-19 Procede permettant de produire un compose a base d'iso-oxazolidinedione

Publications (3)

Publication Number Publication Date
NO20024058L NO20024058L (no) 1999-11-29
NO20024058D0 NO20024058D0 (no) 2002-08-26
NO315198B1 true NO315198B1 (no) 2003-07-28

Family

ID=14371652

Family Applications (4)

Application Number Title Priority Date Filing Date
NO19995851A NO314403B1 (no) 1998-03-30 1999-11-29 Fremstillingsfremgangsmåte for isoksasolidinedionforbindelse
NO20024059A NO315197B1 (no) 1998-03-30 2002-08-26 Fremgangsmåte for fremstilling av et isoksasolylacetatderivat
NO20024058A NO315198B1 (no) 1998-03-30 2002-08-26 Fremgangsmåte for fremstilling av et oksazolyletanolderivat
NO20024060A NO315199B1 (no) 1998-03-30 2002-08-26 Fremgangsmåte for fremstilling av et oksazolyletanolderivat

Family Applications Before (2)

Application Number Title Priority Date Filing Date
NO19995851A NO314403B1 (no) 1998-03-30 1999-11-29 Fremstillingsfremgangsmåte for isoksasolidinedionforbindelse
NO20024059A NO315197B1 (no) 1998-03-30 2002-08-26 Fremgangsmåte for fremstilling av et isoksasolylacetatderivat

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO20024060A NO315199B1 (no) 1998-03-30 2002-08-26 Fremgangsmåte for fremstilling av et oksazolyletanolderivat

Country Status (25)

Country Link
US (4) US6248897B1 (no)
EP (3) EP0992503B1 (no)
JP (1) JP2000143596A (no)
KR (1) KR100321608B1 (no)
CN (4) CN1781915A (no)
AR (1) AR015745A1 (no)
AT (1) ATE258931T1 (no)
AU (1) AU738200B2 (no)
BR (1) BR9906312A (no)
CA (1) CA2291620C (no)
CO (1) CO5080736A1 (no)
CZ (1) CZ296507B6 (no)
DE (1) DE69914557T2 (no)
ES (1) ES2211053T3 (no)
HU (1) HUP0003273A3 (no)
IL (1) IL133146A (no)
NO (4) NO314403B1 (no)
NZ (1) NZ501896A (no)
PE (1) PE20000359A1 (no)
RU (1) RU2180663C2 (no)
SG (1) SG73627A1 (no)
SK (1) SK161499A3 (no)
TW (1) TWI224594B (no)
WO (1) WO1999050267A1 (no)
ZA (1) ZA997705B (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0992503B1 (en) * 1998-03-30 2004-02-04 Japan Tobacco Inc. Process for producing isooxazolidinedione compound
US6768008B2 (en) 2000-04-24 2004-07-27 Aryx Therapeutics Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
US6784199B2 (en) 2000-09-21 2004-08-31 Aryx Therapeutics Isoxazolidine compounds useful in the treatment of diabetes, hyperlipidemia, and atherosclerosis in mammals
US6958355B2 (en) 2000-04-24 2005-10-25 Aryx Therapeutics, Inc. Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
US6680387B2 (en) 2000-04-24 2004-01-20 Aryx Therapeutics Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
BR0208956A (pt) * 2001-04-16 2004-07-13 Tanabe Seiyaku Co Abridor de canais de k ativados por cálcio de grande condutância
US6696474B2 (en) * 2002-04-03 2004-02-24 Warner Lambert Co. Llc. Antidiabetic agents
US6716842B2 (en) * 2002-04-05 2004-04-06 Warner-Lambert Company, Llc Antidiabetic agents
TWI343915B (en) * 2002-10-07 2011-06-21 Hoffmann La Roche Chirale ppar agonists
DE10328174A1 (de) * 2003-06-24 2005-01-13 Bayer Healthcare Ag Verfahren zur Herstellung von Aryloxazolylethylalkohol
WO2006100181A2 (en) * 2005-03-22 2006-09-28 F. Hoffmann-La Roche Ag New salt and polymorphs of a dpp-iv inhibitor
EP1892231A1 (en) * 2006-08-21 2008-02-27 Bayer Schering Pharma Aktiengesellschaft A large scale method for the deoxofluorination of ketones

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1859667A (en) * 1930-05-14 1932-05-24 J K Gruner Lumber Company Jointed lumber
JPS58219169A (ja) 1982-06-15 1983-12-20 Takeda Chem Ind Ltd オキサゾ−ル酢酸誘導体
CN1003445B (zh) 1984-10-03 1989-03-01 武田药品工业株式会社 噻唑烷二酮衍生物，其制备方法和用途
US5059720A (en) * 1990-01-31 1991-10-22 E. I. Du Pont De Nemours And Company Hydroxy containing fluorovinyl compounds and polymers thereof
AU645112B2 (en) 1990-08-23 1994-01-06 Pfizer Inc. Hypoglycemic hydroxyurea derivatives
CA2075553A1 (en) * 1992-08-07 1994-02-08 George Zafir Insulated panel
AU668735B2 (en) * 1992-12-28 1996-05-16 Ig-Technical Research Inc. Refractory heat-insulating panel
JPH07188227A (ja) 1993-12-24 1995-07-25 Japan Tobacco Inc チアゾリジン誘導体及びオキサゾール誘導体
DK0684242T3 (da) 1993-12-27 1999-11-01 Japan Tobacco Inc Isoxazolidindionderivat og anvendelse deraf
TW403748B (en) * 1994-11-02 2000-09-01 Takeda Chemical Industries Ltd An oxazolidinedione derivative, its production and a pharmaceutical composition for lowering blood sugar and lipid in blood comprising the same
NZ314406A (en) * 1996-03-18 2000-12-22 Sankyo Co Treatment or prophylaxis of pancreatitis with a medicament containing an insulin sensitiser including oxazoles and thiazoles
US5768850A (en) * 1997-02-04 1998-06-23 Chen; Alen Method for erecting floor boards and a board assembly using the method
EP0992503B1 (en) * 1998-03-30 2004-02-04 Japan Tobacco Inc. Process for producing isooxazolidinedione compound
DE19851200C1 (de) * 1998-11-06 2000-03-30 Kronotex Gmbh Holz Und Kunstha Fußbodenpaneele
US8234204B2 (en) * 2000-11-13 2012-07-31 Goldman, Sachs & Co. Method and system for matching short trading positions with long trading positions

Also Published As

Publication number Publication date
CA2291620C (en) 2003-10-07
PE20000359A1 (es) 2000-05-17
JP2000143596A (ja) 2000-05-23
NO20024059D0 (no) 2002-08-26
NZ501896A (en) 2000-11-24
US20010039352A1 (en) 2001-11-08
IL133146A0 (en) 2001-03-19
EP0992503A4 (en) 2001-11-07
CN1511833A (zh) 2004-07-14
CZ422499A3 (cs) 2000-04-12
EP1384722A8 (en) 2004-09-08
IL133146A (en) 2004-02-08
SK161499A3 (en) 2000-06-12
BR9906312A (pt) 2000-07-11
SG73627A1 (en) 2000-06-20
AU738200B2 (en) 2001-09-13
CO5080736A1 (es) 2001-09-25
NO315199B1 (no) 2003-07-28
NO995851L (no) 1999-11-29
CN1495174A (zh) 2004-05-12
NO20024058D0 (no) 2002-08-26
KR20010013044A (ko) 2001-02-26
EP1384722A1 (en) 2004-01-28
NO20024058L (no) 1999-11-29
ZA997705B (en) 2000-06-27
CZ296507B6 (cs) 2006-03-15
CN1272109A (zh) 2000-11-01
DE69914557D1 (de) 2004-03-11
CN1232511C (zh) 2005-12-21
US20020188133A1 (en) 2002-12-12
CA2291620A1 (en) 1999-10-07
EP0992503A1 (en) 2000-04-12
CN1235887C (zh) 2006-01-11
KR100321608B1 (ko) 2002-02-02
NO995851D0 (no) 1999-11-29
NO315197B1 (no) 2003-07-28
HUP0003273A3 (en) 2002-02-28
EP0992503B1 (en) 2004-02-04
US20050159466A1 (en) 2005-07-21
WO1999050267A1 (fr) 1999-10-07
US6444827B2 (en) 2002-09-03
US6248897B1 (en) 2001-06-19
NO314403B1 (no) 2003-03-17
ATE258931T1 (de) 2004-02-15
HUP0003273A2 (hu) 2002-01-28
NO20024060D0 (no) 2002-08-26
AU2854899A (en) 1999-10-18
DE69914557T2 (de) 2005-01-05
ES2211053T3 (es) 2004-07-01
CN1130361C (zh) 2003-12-10
TWI224594B (en) 2004-12-01
NO20024059L (no) 1999-11-29
US6699996B2 (en) 2004-03-02
AR015745A1 (es) 2001-05-16
EP1375499A8 (en) 2004-09-08
NO20024060L (no) 1999-11-29
US6995271B2 (en) 2006-02-07
EP1375499A1 (en) 2004-01-02
CN1781915A (zh) 2006-06-07
RU2180663C2 (ru) 2002-03-20

Similar Documents

Publication Publication Date Title
NO315198B1 (no) Fremgangsmåte for fremstilling av et oksazolyletanolderivat
WO2000023407A3 (en) Ureido-thiobutyric acid derivatives as ppar-agonists
EP1020434A4 (en) 3-AMIDINOANILINE DERIVATIVES, INHIBITORS OF THE ACTIVATED BLOOD COINTENANCE FACTOR X AND INTERMEDIATE PRODUCTS FOR PRODUCING BOTH
NO20051418L (no) Hydroksyalkyl stivelsesderivater
WO1997047270A3 (en) Novel anti-viral compounds
ES2132415T3 (es) Nuevos derivados de 5-pirrolil-2-piridilmetilsulfinilbencimidazol.
KR900012919A (ko) 벤조 융합된 n-함유 헤테로사이클 유도체
GB9916405D0 (en) Compounds for mass spectrometry
CA2192268A1 (en) Amino alcohol derivative and method for preparing the same
CA2385200A1 (en) 4-hydroxybiphenyl hydrazide derivatives
NO995924L (no) Fremgangsmåte ved fremstillingen av 1,4,7,10- tetraazacyklododekan-1,4,7-trieddiksyre og derivater derav
AU6077798A (en) A condensed piperidine compound
EP1043312A4 (en) HETEROCYCLIC COMPOUNDS HAVING NOS-INHIBITING ACTIVITIES
WO1997031016A3 (en) New inhibitors of sh2-mediated processes
NO964551L (no) Imidazolderivater og fremgangsmåte for fremstilling av slike
EP1043311A4 (en) BIPHENYLAMIDINE DERIVATIVES
CA2336380A1 (en) Novel antihistaminic piperidine derivatives and intermediates for the preparation thereof
EP0787732A3 (en) Phthalocyanines
CA2258539A1 (en) Ring-fused dihydropyranes, process for the preparation and use thereof
DE69533214D1 (de) 2,3-Dihydro-1H-isoindolderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Hemmer der Serotoninwiederaufnahme
CA2092919A1 (en) Epoxysuccinamic acid derivatives
CA2174797A1 (en) Cyanobenzenesulfenyl halide and process for preparation of 3-substituted benzisothiazole using the same
NO20020073L (no) Fremgangsmåte ved fremstilling av trisykliske aminoalkoholderivater
NO20021574L (no) Fremgangsmåte for å forbedre opplöseligheten av trisykliske aminoalkoholderivater
EP1092714A3 (en) Process for the synthesis of benzo[b]thiophenes

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees