NO315045B1 - Nye cykliske diaminforbindelser og medisiner inneholdende de samme - Google Patents
Nye cykliske diaminforbindelser og medisiner inneholdende de samme Download PDFInfo
- Publication number
- NO315045B1 NO315045B1 NO19995783A NO995783A NO315045B1 NO 315045 B1 NO315045 B1 NO 315045B1 NO 19995783 A NO19995783 A NO 19995783A NO 995783 A NO995783 A NO 995783A NO 315045 B1 NO315045 B1 NO 315045B1
- Authority
- NO
- Norway
- Prior art keywords
- mmol
- group
- give
- solution
- acetamide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/28—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/70—Sulfur atoms
- C07D277/74—Sulfur atoms substituted by carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6509—Six-membered rings
- C07F9/650952—Six-membered rings having the nitrogen atoms in the positions 1 and 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP14989297 | 1997-05-26 | ||
| PCT/JP1998/002300 WO1998054153A1 (fr) | 1997-05-26 | 1998-05-26 | Nouveaux composes de diamine cycliques et medicament contenant ces composes |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO995783D0 NO995783D0 (no) | 1999-11-25 |
| NO995783L NO995783L (no) | 2000-01-26 |
| NO315045B1 true NO315045B1 (no) | 2003-06-30 |
Family
ID=15484915
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19995783A NO315045B1 (no) | 1997-05-26 | 1999-11-25 | Nye cykliske diaminforbindelser og medisiner inneholdende de samme |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0987254B1 (cs) |
| JP (1) | JP3614865B2 (cs) |
| KR (1) | KR100549804B1 (cs) |
| CN (1) | CN1118457C (cs) |
| AT (1) | ATE285402T1 (cs) |
| AU (1) | AU728151B2 (cs) |
| CA (1) | CA2290744C (cs) |
| CZ (1) | CZ297451B6 (cs) |
| DE (1) | DE69828276T2 (cs) |
| ES (1) | ES2235328T3 (cs) |
| HU (1) | HUP0002294A3 (cs) |
| ID (1) | ID23377A (cs) |
| NO (1) | NO315045B1 (cs) |
| NZ (1) | NZ501156A (cs) |
| PT (1) | PT987254E (cs) |
| RU (1) | RU2207341C2 (cs) |
| SK (1) | SK284891B6 (cs) |
| TW (1) | TW589308B (cs) |
| WO (1) | WO1998054153A1 (cs) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2321237A1 (en) | 1998-02-25 | 1999-09-02 | Masami Muraoka | Pyridone derivatives and process for producing the same |
| US6452008B2 (en) | 1998-02-25 | 2002-09-17 | Sumitomo Pharmaceuticals Company, Limited | Pyridone derivatives and process for preparing the same |
| JP4717305B2 (ja) * | 1999-06-28 | 2011-07-06 | 富士フイルム株式会社 | ベンズイミダゾール化合物及びこれを含む医薬 |
| CA2377230C (en) | 1999-06-30 | 2009-06-02 | Kozo Aoki | Benzimidazole compounds and medicaments comprising the same |
| ATE262522T1 (de) * | 1999-07-07 | 2004-04-15 | Fuji Photo Film Co Ltd | Benzimidazolverbindungen |
| EP1431294A4 (en) * | 2001-08-22 | 2004-09-15 | Kowa Co | ACAT INHIBITOR WITH SELECTIVITY FOR VESSEL WALLS |
| US20060165605A1 (en) * | 2001-12-28 | 2006-07-27 | Ye-Mon Chen | Process to regenerate fcc spent catalyst |
| JP4571505B2 (ja) * | 2002-11-28 | 2010-10-27 | 興和株式会社 | １−［２−（ベンズイミダゾール−２−イルチオ）エチル］ピペラジン又はその塩の製造法 |
| DE60328545D1 (de) * | 2002-12-05 | 2009-09-03 | Cv Therapeutics Inc | Substituierte Piperazinderivate und ihre Verwendung als Inhibitoren der Fettsäureoxidation |
| JP4745666B2 (ja) | 2002-12-12 | 2011-08-10 | 興和株式会社 | ヒドロキシアルキル環状ジアミン化合物 |
| MY140618A (en) * | 2003-02-28 | 2009-12-31 | Kowa Co | Method for preparing acid addition salts of polyacidic basic compounds |
| EP1631565A1 (en) * | 2003-05-07 | 2006-03-08 | Actelion Pharmaceuticals Ltd. | Piperazine-alkyl-ureido derivatives |
| EP1627875B1 (en) * | 2003-05-28 | 2013-07-31 | Kowa Co., Ltd. | Method for producing cyclic diamine derivative or salt thereof |
| MY140849A (en) | 2003-07-07 | 2010-01-29 | Kowa Co | 2, 4-bis (trifluoroethoxy) pyridine compound and drug containing the compound |
| US7884106B2 (en) | 2003-08-29 | 2011-02-08 | Kowa Company, Ltd. | Method of stabilizing lipid-rich plaque and method of preventing rupture thereof |
| JP2007512359A (ja) | 2003-11-19 | 2007-05-17 | メタバシス・セラピューティクス・インコーポレイテッド | 新規なリン含有甲状腺ホルモン様物質 |
| US7163944B2 (en) * | 2004-01-26 | 2007-01-16 | Kowa Co., Ltd. | Cyclic diamine compound and pharmaceutical containing the same |
| WO2006003974A1 (ja) * | 2004-06-30 | 2006-01-12 | Kowa Co., Ltd. | 環状ジアミン誘導体の製造法 |
| CN101039652A (zh) * | 2004-08-16 | 2007-09-19 | 宝洁公司 | 2－(氨基或取代的氨基)－5,6－取代的苯酚化合物，包含该化合物的染料组合物以及它们的应用 |
| NZ555325A (en) | 2004-10-27 | 2009-07-31 | Daiichi Sankyo Co Ltd | Benzene compound having 2 or more substituents |
| TW200619204A (en) * | 2004-12-10 | 2006-06-16 | Kowa Co | Method for reduction, stabilization and prevention of rupture of lipid rich plaque |
| FR2920770B1 (fr) * | 2007-09-06 | 2009-10-30 | Galderma Res & Dev | Nouveaux derives de phenylurees, inhibiteurs de l'enzyme soat-1, compositions pharmaceutiques et cosmetiques les contenant |
| FR2920769B1 (fr) * | 2007-09-06 | 2009-10-30 | Galderma Res & Dev | Nouveaux derives de n-phenyl acetamide, inhibiteurs de l'enzyme soat-1, compositions pharmaceutiques et cosmetiques les contenant |
| FR2920774B1 (fr) * | 2007-09-06 | 2009-10-30 | Galderma Res & Dev | Nouveaux derives de n-phenul acatamide, inhibiteurs de l'enzyme soat-1, compositions pharmaceutiques et cosmetiques les contentant |
| JP5291979B2 (ja) | 2008-04-24 | 2013-09-18 | 株式会社フジクラ | 圧力センサ及びその製造方法と、該圧力センサを備えた電子部品 |
| US20120046364A1 (en) | 2009-02-10 | 2012-02-23 | Metabasis Therapeutics, Inc. | Novel Sulfonic Acid-Containing Thyromimetics, and Methods for Their Use |
| CN102711762A (zh) * | 2009-12-29 | 2012-10-03 | 兴和株式会社 | 口服用固体医药组合物 |
| JPWO2011081118A1 (ja) * | 2009-12-29 | 2013-05-13 | 興和株式会社 | 経口投与用医薬組成物 |
| US20130066075A1 (en) * | 2010-05-19 | 2013-03-14 | Kowa Company, Ltd. | Prophylactic and/or therapeutic agent for non-alcoholic steatohepatitis |
| WO2014147182A2 (en) * | 2013-03-20 | 2014-09-25 | Bayer Pharma Aktiengesellschaft | Novel compounds |
| CN105693524A (zh) * | 2014-11-28 | 2016-06-22 | 浙江省化工研究院有限公司 | 一种硝基化合物的制备方法 |
| WO2018097149A1 (ja) * | 2016-11-24 | 2018-05-31 | 帝人ファーマ株式会社 | スルフィド化合物の製造方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3629208A (en) * | 1969-06-18 | 1971-12-21 | Monsanto Co | N-aminoalkyl thiazolesulfenamides as vulcanization accelerators |
| DD290192A5 (de) * | 1986-11-13 | 1991-05-23 | Eisai Co. Ltd,Jp | Pyridinderivat mit antiulzeroeser wirkung |
| CA2003283A1 (en) * | 1988-12-05 | 1990-06-05 | C. Anne Higley | Imidazoles for the treatment of atherosclerosis |
| WO1992007825A1 (en) * | 1990-11-05 | 1992-05-14 | Taisho Pharmaceutical Co., Ltd. | Phenol derivative |
| RU2036057C1 (ru) * | 1991-01-25 | 1995-05-27 | Александр Петрович Войнов | Устройство для плющения зубьев пил |
| US5721266A (en) * | 1993-05-28 | 1998-02-24 | Warner-Lambert Company | Substituted imidazolinyl-imidazolines as antagonists of SH-2 binding and therapeutic uses thereof |
| US5596001A (en) * | 1993-10-25 | 1997-01-21 | Pfizer Inc. | 4-aryl-3-(heteroarylureido)quinoline derivatves |
| JP4191269B2 (ja) * | 1996-05-17 | 2008-12-03 | 興和株式会社 | 新規なアニリド化合物及びこれを含有する医薬 |
| US6362208B1 (en) * | 1997-03-25 | 2002-03-26 | Kowa Company, Ltd. | Anilide compounds and drugs containing the same |
| CA2303781A1 (en) * | 1997-11-14 | 1999-05-27 | Kowa Company, Ltd. | Novel amide compounds and drugs containing the same |
-
1998
- 1998-05-26 DE DE69828276T patent/DE69828276T2/de not_active Expired - Lifetime
- 1998-05-26 AT AT98921809T patent/ATE285402T1/de active
- 1998-05-26 ID IDW991669A patent/ID23377A/id unknown
- 1998-05-26 WO PCT/JP1998/002300 patent/WO1998054153A1/ja active IP Right Grant
- 1998-05-26 KR KR1019997010894A patent/KR100549804B1/ko not_active Expired - Fee Related
- 1998-05-26 AU AU74512/98A patent/AU728151B2/en not_active Ceased
- 1998-05-26 CZ CZ0415999A patent/CZ297451B6/cs not_active IP Right Cessation
- 1998-05-26 ES ES98921809T patent/ES2235328T3/es not_active Expired - Lifetime
- 1998-05-26 JP JP50047199A patent/JP3614865B2/ja not_active Expired - Fee Related
- 1998-05-26 SK SK1582-99A patent/SK284891B6/sk not_active IP Right Cessation
- 1998-05-26 HU HU0002294A patent/HUP0002294A3/hu unknown
- 1998-05-26 PT PT98921809T patent/PT987254E/pt unknown
- 1998-05-26 RU RU99128053/04A patent/RU2207341C2/ru not_active IP Right Cessation
- 1998-05-26 TW TW087108155A patent/TW589308B/zh not_active IP Right Cessation
- 1998-05-26 CN CN98805498A patent/CN1118457C/zh not_active Expired - Fee Related
- 1998-05-26 CA CA002290744A patent/CA2290744C/en not_active Expired - Fee Related
- 1998-05-26 NZ NZ501156A patent/NZ501156A/en not_active IP Right Cessation
- 1998-05-26 EP EP98921809A patent/EP0987254B1/en not_active Expired - Lifetime
-
1999
- 1999-11-25 NO NO19995783A patent/NO315045B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1998054153A1 (fr) | 1998-12-03 |
| NO995783D0 (no) | 1999-11-25 |
| AU7451298A (en) | 1998-12-30 |
| EP0987254A1 (en) | 2000-03-22 |
| NZ501156A (en) | 2002-02-01 |
| RU2207341C2 (ru) | 2003-06-27 |
| DE69828276T2 (de) | 2005-12-15 |
| AU728151B2 (en) | 2001-01-04 |
| DE69828276D1 (de) | 2005-01-27 |
| CZ297451B6 (cs) | 2006-12-13 |
| HUP0002294A3 (en) | 2001-10-29 |
| CA2290744C (en) | 2009-12-22 |
| CN1118457C (zh) | 2003-08-20 |
| HUP0002294A2 (hu) | 2001-09-28 |
| ATE285402T1 (de) | 2005-01-15 |
| CA2290744A1 (en) | 1998-12-03 |
| ES2235328T3 (es) | 2005-07-01 |
| CN1258283A (zh) | 2000-06-28 |
| ID23377A (id) | 2000-04-20 |
| KR20010012926A (ko) | 2001-02-26 |
| KR100549804B1 (ko) | 2006-02-08 |
| EP0987254A4 (en) | 2000-09-13 |
| SK284891B6 (sk) | 2006-02-02 |
| JP3614865B2 (ja) | 2005-01-26 |
| PT987254E (pt) | 2005-04-29 |
| NO995783L (no) | 2000-01-26 |
| SK158299A3 (en) | 2001-02-12 |
| TW589308B (en) | 2004-06-01 |
| EP0987254B1 (en) | 2004-12-22 |
| CZ415999A3 (cs) | 2000-05-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |