NO314434B1 - Lav-viskositets oftalmisk blanding - Google Patents
Lav-viskositets oftalmisk blanding Download PDFInfo
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- NO314434B1 NO314434B1 NO19964070A NO964070A NO314434B1 NO 314434 B1 NO314434 B1 NO 314434B1 NO 19964070 A NO19964070 A NO 19964070A NO 964070 A NO964070 A NO 964070A NO 314434 B1 NO314434 B1 NO 314434B1
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- Norway
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- 239000000243 solution Substances 0.000 claims description 34
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- 229920002125 Sokalan® Polymers 0.000 claims description 22
- 235000002639 sodium chloride Nutrition 0.000 claims description 20
- PEDCQBHIVMGVHV-UHFFFAOYSA-N glycerol group Chemical group OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 18
- 150000003839 salts Chemical class 0.000 claims description 17
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical group [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 15
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- 239000013543 active substance Substances 0.000 claims description 14
- TWBNMYSKRDRHAT-RCWTXCDDSA-N (S)-timolol hemihydrate Chemical compound O.CC(C)(C)NC[C@H](O)COC1=NSN=C1N1CCOCC1.CC(C)(C)NC[C@H](O)COC1=NSN=C1N1CCOCC1 TWBNMYSKRDRHAT-RCWTXCDDSA-N 0.000 claims description 12
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- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 claims description 5
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- 229910021538 borax Inorganic materials 0.000 claims description 2
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- 239000012458 free base Substances 0.000 claims description 2
- IXHBTMCLRNMKHZ-LBPRGKRZSA-N levobunolol Chemical compound O=C1CCCC2=C1C=CC=C2OC[C@@H](O)CNC(C)(C)C IXHBTMCLRNMKHZ-LBPRGKRZSA-N 0.000 claims description 2
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- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims description 2
- 235000011083 sodium citrates Nutrition 0.000 claims description 2
- 235000010339 sodium tetraborate Nutrition 0.000 claims description 2
- 229940127230 sympathomimetic drug Drugs 0.000 claims description 2
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- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 1
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- 208000010412 Glaucoma Diseases 0.000 description 1
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- HRLIOXLXPOHXTA-UHFFFAOYSA-N medetomidine Chemical compound C=1C=CC(C)=C(C)C=1C(C)C1=CN=C[N]1 HRLIOXLXPOHXTA-UHFFFAOYSA-N 0.000 description 1
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- HYIMSNHJOBLJNT-UHFFFAOYSA-N nifedipine Chemical compound COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1C1=CC=CC=C1[N+]([O-])=O HYIMSNHJOBLJNT-UHFFFAOYSA-N 0.000 description 1
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- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- 229940002612 prodrug Drugs 0.000 description 1
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- 230000002035 prolonged effect Effects 0.000 description 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
- 238000000518 rheometry Methods 0.000 description 1
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- 125000000467 secondary amino group Chemical group [H]N([*:1])[*:2] 0.000 description 1
- 229950004070 sezolamide Drugs 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9401108A SE9401108D0 (sv) | 1994-03-31 | 1994-03-31 | Ophthalmic composition I |
| PCT/FI1995/000166 WO1995026711A1 (fr) | 1994-03-31 | 1995-03-29 | Composition ophtalmique a viscosite reduite |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO964070D0 NO964070D0 (no) | 1996-09-27 |
| NO964070L NO964070L (no) | 1996-11-28 |
| NO314434B1 true NO314434B1 (no) | 2003-03-24 |
Family
ID=20393511
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19964070A NO314434B1 (no) | 1994-03-31 | 1996-09-27 | Lav-viskositets oftalmisk blanding |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US5710182A (fr) |
| EP (1) | EP0752847B1 (fr) |
| JP (1) | JPH10503470A (fr) |
| KR (1) | KR100365914B1 (fr) |
| CN (1) | CN1112918C (fr) |
| AT (1) | ATE202921T1 (fr) |
| AU (1) | AU694497B2 (fr) |
| BG (1) | BG63145B1 (fr) |
| BR (1) | BR9507438A (fr) |
| CA (1) | CA2186734A1 (fr) |
| CZ (1) | CZ290987B6 (fr) |
| DE (2) | DE752847T1 (fr) |
| DK (1) | DK0752847T3 (fr) |
| EE (1) | EE03661B1 (fr) |
| ES (1) | ES2161874T3 (fr) |
| GR (1) | GR3036763T3 (fr) |
| HK (1) | HK1013953A1 (fr) |
| HU (1) | HU223071B1 (fr) |
| MX (1) | MX9603918A (fr) |
| NO (1) | NO314434B1 (fr) |
| PL (1) | PL179433B1 (fr) |
| PT (1) | PT752847E (fr) |
| RO (1) | RO115409B1 (fr) |
| RU (1) | RU2139016C1 (fr) |
| SE (1) | SE9401108D0 (fr) |
| SK (1) | SK280492B6 (fr) |
| WO (1) | WO1995026711A1 (fr) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9718568D0 (en) | 1997-09-03 | 1997-11-05 | Chauvin Pharmaceuticals Limite | Compositions |
| AU4808000A (en) | 1999-04-28 | 2000-11-10 | Situs Corporation | Drug delivery system |
| US6852688B2 (en) | 2000-03-10 | 2005-02-08 | University Of Florida | Compositions for treating diabetic retinopathy and methods of using same |
| WO2003070219A1 (fr) * | 2002-02-22 | 2003-08-28 | Santen Pharmaceutical Co., Ltd. | Systeme d'administration de medicament destine a administrer de facon subconjonctivale des grains fins |
| JP2005521690A (ja) * | 2002-02-22 | 2005-07-21 | ファルマシア・コーポレーション | ゴム系を含む眼科用製剤 |
| CN100453066C (zh) * | 2002-12-04 | 2009-01-21 | 参天制药株式会社 | 利用结膜下储存库的药物释放系统 |
| JP2004196787A (ja) * | 2002-12-04 | 2004-07-15 | Santen Pharmaceut Co Ltd | 結膜下デポによるドラッグデリバリーシステム |
| US7947295B2 (en) * | 2003-06-13 | 2011-05-24 | Alcon, Inc. | Ophthalmic compositions containing a synergistic combination of two polymers |
| KR20120062846A (ko) * | 2003-06-13 | 2012-06-14 | 알콘, 인코퍼레이티드 | 시너지성의 2개의 폴리머 배합물을 포함하는 안과용 조성물 |
| KR101160702B1 (ko) * | 2003-08-20 | 2012-06-28 | 산텐 세이야꾸 가부시키가이샤 | 미립자 테논낭하 투여 약물 전달 시스템 |
| TWI367098B (en) * | 2004-12-23 | 2012-07-01 | Kowa Co | Treating agent for glaucoma |
| US7862552B2 (en) | 2005-05-09 | 2011-01-04 | Boston Scientific Scimed, Inc. | Medical devices for treating urological and uterine conditions |
| DE102005035986B4 (de) * | 2005-07-28 | 2009-10-15 | Bausch & Lomb Incorporated | Steriles tropfbares mehrphasiges emulgatorfreies ophthalmisches Präparat |
| WO2010024930A2 (fr) * | 2008-08-28 | 2010-03-04 | President And Fellows Of Harvard College | Analogues de cortistatine et leurs synthèses |
| EP2383286A1 (fr) | 2010-04-30 | 2011-11-02 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Procédés et compositions pour le traitement des maladies rétiniennes dégénératives |
| WO2012108489A1 (fr) * | 2011-02-10 | 2012-08-16 | 参天製薬株式会社 | Composition aqueuse présentant une meilleure pénétrabilité des médicaments hydrophiles |
| US20150038557A1 (en) | 2012-02-24 | 2015-02-05 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods and compositions for treatment of retinal degenerative diseases |
| ES2709480T3 (es) | 2013-12-24 | 2019-04-16 | Harvard College | Análogos de cortistatina y síntesis y usos de los mismos |
| EP3294298A4 (fr) | 2015-05-08 | 2018-10-17 | President and Fellows of Harvard College | Analogues de la cortistatine, synthèses, et utilisations de ces derniers |
| WO2017004411A1 (fr) | 2015-07-01 | 2017-01-05 | President And Fellows Of Harvard College | Analogues de la cortistatine, et synthèses et leurs utilisations |
| ES2908479T3 (es) | 2015-08-26 | 2022-04-29 | Achillion Pharmaceuticals Inc | Compuestos para el tratamiento de trastornos inmunitarios e inflamatorios |
| AR106018A1 (es) | 2015-08-26 | 2017-12-06 | Achillion Pharmaceuticals Inc | Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos |
| WO2017143220A1 (fr) | 2016-02-17 | 2017-08-24 | Children's Medical Center Corporation | Ffa1 (gpr40) utilisé comme cible thérapeutique pour des maladies ou des troubles neuronaux liés à l'angiogenèse |
| EP3448389B1 (fr) | 2016-06-27 | 2021-09-29 | Achillion Pharmaceuticals, Inc. | Composés de quinazoline et d'indole destinés au traitement de troubles médicaux |
| WO2018033854A1 (fr) | 2016-08-15 | 2018-02-22 | Santen Pharmaceutical Co., Ltd. | Composition ophtalmique et procédé de traitement de l'hypertension oculaire et du glaucome |
| IL297367A (en) | 2016-08-19 | 2022-12-01 | Orasis Pharmaceuticals Ltd | Ophthalmic pharmaceutical preparations and uses related to them |
| CN110603252A (zh) | 2017-03-01 | 2019-12-20 | 艾其林医药公司 | 用于治疗医学障碍的芳基、杂芳基和杂环药物化合物 |
| WO2018209051A1 (fr) * | 2017-05-11 | 2018-11-15 | Nevakar Inc. | Compositions pharmaceutiques d'atropine |
| CN111902141A (zh) | 2018-03-26 | 2020-11-06 | C4医药公司 | 用于ikaros降解的羟脑苷脂结合剂 |
| JP2021535112A (ja) | 2018-08-20 | 2021-12-16 | アキリオン ファーマシューティカルズ，インコーポレーテッド | 補体ｄ因子の医学的障害の治療のための医薬化合物 |
| CN113365617A (zh) | 2018-10-16 | 2021-09-07 | 乔治亚州立大学研究基金会股份有限公司 | 用于医学疾病治疗的一氧化碳前药 |
| WO2022169959A1 (fr) * | 2021-02-04 | 2022-08-11 | Sydnexis, Inc. | Compositions ophtalmiques pour la presbytie |
| EP4088714A1 (fr) | 2021-05-10 | 2022-11-16 | Warszawskie Zaklady Farmaceutyczne Polfa S.A. | Composition pharmaceutique ophtalmique comprenant de l'atropine |
| EP4088713A1 (fr) | 2021-05-10 | 2022-11-16 | Warszawskie Zaklady Farmaceutyczne Polfa S.A. | Composition pharmaceutique ophtalmique comprenant de l'atropine |
| CN113786380A (zh) * | 2021-09-18 | 2021-12-14 | 华北制药股份有限公司 | 一种硝酸毛果芸香碱眼用凝胶及其制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6056684B2 (ja) * | 1977-11-07 | 1985-12-11 | 東興薬品工業株式会社 | 点眼剤 |
| US5252318A (en) * | 1990-06-15 | 1993-10-12 | Allergan, Inc. | Reversible gelation compositions and methods of use |
| FR2678832B1 (fr) * | 1991-07-10 | 1995-03-17 | Europhta Sa Laboratoire | Nouvelles compositions ophtalmiques a resorption amelioree et leurs procedes de preparation. |
-
1994
- 1994-03-31 SE SE9401108A patent/SE9401108D0/xx unknown
-
1995
- 1995-03-29 PL PL95316584A patent/PL179433B1/pl unknown
- 1995-03-29 HU HU9602691A patent/HU223071B1/hu active IP Right Grant
- 1995-03-29 RU RU96119953A patent/RU2139016C1/ru active
- 1995-03-29 CA CA002186734A patent/CA2186734A1/fr not_active Abandoned
- 1995-03-29 DE DE0752847T patent/DE752847T1/de active Pending
- 1995-03-29 BR BR9507438A patent/BR9507438A/pt not_active IP Right Cessation
- 1995-03-29 JP JP7525423A patent/JPH10503470A/ja not_active Ceased
- 1995-03-29 PT PT95914362T patent/PT752847E/pt unknown
- 1995-03-29 AT AT95914362T patent/ATE202921T1/de active
- 1995-03-29 AU AU21389/95A patent/AU694497B2/en not_active Ceased
- 1995-03-29 DK DK95914362T patent/DK0752847T3/da active
- 1995-03-29 MX MX9603918A patent/MX9603918A/es unknown
- 1995-03-29 EP EP95914362A patent/EP0752847B1/fr not_active Expired - Lifetime
- 1995-03-29 WO PCT/FI1995/000166 patent/WO1995026711A1/fr active IP Right Grant
- 1995-03-29 US US08/535,037 patent/US5710182A/en not_active Expired - Lifetime
- 1995-03-29 SK SK1239-96A patent/SK280492B6/sk not_active IP Right Cessation
- 1995-03-29 EE EE9600120A patent/EE03661B1/xx unknown
- 1995-03-29 KR KR1019960705391A patent/KR100365914B1/ko not_active IP Right Cessation
- 1995-03-29 ES ES95914362T patent/ES2161874T3/es not_active Expired - Lifetime
- 1995-03-29 CZ CZ19962865A patent/CZ290987B6/cs not_active IP Right Cessation
- 1995-03-29 CN CN95192185A patent/CN1112918C/zh not_active Expired - Fee Related
- 1995-03-29 DE DE69521686T patent/DE69521686T2/de not_active Expired - Lifetime
- 1995-03-29 RO RO96-01877A patent/RO115409B1/ro unknown
-
1996
- 1996-09-27 NO NO19964070A patent/NO314434B1/no not_active IP Right Cessation
- 1996-10-16 BG BG100915A patent/BG63145B1/bg unknown
-
1998
- 1998-12-23 HK HK98115146A patent/HK1013953A1/xx not_active IP Right Cessation
-
2001
- 2001-09-28 GR GR20010401621T patent/GR3036763T3/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1K | Patent expired |