NO313415B1 - Oksazolidiner, fremgangsmåte for fremstilling derav, farmasöytiske preparater, fremgangsmåte for fremstilling derav,forbindelsene 5-HT2A-antagonister, samt anvendelse avforbindelsene til fremstilling av legemidler - Google Patents
Oksazolidiner, fremgangsmåte for fremstilling derav, farmasöytiske preparater, fremgangsmåte for fremstilling derav,forbindelsene 5-HT2A-antagonister, samt anvendelse avforbindelsene til fremstilling av legemidler Download PDFInfo
- Publication number
- NO313415B1 NO313415B1 NO19994106A NO994106A NO313415B1 NO 313415 B1 NO313415 B1 NO 313415B1 NO 19994106 A NO19994106 A NO 19994106A NO 994106 A NO994106 A NO 994106A NO 313415 B1 NO313415 B1 NO 313415B1
- Authority
- NO
- Norway
- Prior art keywords
- formula
- compounds
- indolyl
- oxazolidin
- piperidinylmethyl
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
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- A—HUMAN NECESSITIES
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P25/06—Antimigraine agents
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
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- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19707628A DE19707628A1 (de) | 1997-02-26 | 1997-02-26 | Oxazolidinone |
| PCT/EP1998/000637 WO1998038189A1 (de) | 1997-02-26 | 1998-02-06 | Oxazolidinone als 5-ht2a-antagonisten |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO994106D0 NO994106D0 (no) | 1999-08-25 |
| NO994106L NO994106L (no) | 1999-10-19 |
| NO313415B1 true NO313415B1 (no) | 2002-09-30 |
Family
ID=7821498
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19994106A NO313415B1 (no) | 1997-02-26 | 1999-08-25 | Oksazolidiner, fremgangsmåte for fremstilling derav, farmasöytiske preparater, fremgangsmåte for fremstilling derav,forbindelsene 5-HT2A-antagonister, samt anvendelse avforbindelsene til fremstilling av legemidler |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US6462056B1 (ja) |
| EP (1) | EP0964863B1 (ja) |
| JP (2) | JP4402175B2 (ja) |
| KR (1) | KR20000075697A (ja) |
| CN (1) | CN1177847C (ja) |
| AR (1) | AR010899A1 (ja) |
| AT (1) | ATE240954T1 (ja) |
| AU (1) | AU739251B2 (ja) |
| BR (1) | BR9807765A (ja) |
| CA (1) | CA2281918C (ja) |
| CZ (1) | CZ299199A3 (ja) |
| DE (2) | DE19707628A1 (ja) |
| DK (1) | DK0964863T3 (ja) |
| ES (1) | ES2197466T3 (ja) |
| HU (1) | HUP0001093A3 (ja) |
| ID (1) | ID22838A (ja) |
| NO (1) | NO313415B1 (ja) |
| PL (1) | PL335100A1 (ja) |
| PT (1) | PT964863E (ja) |
| RU (1) | RU2196140C2 (ja) |
| SK (1) | SK112799A3 (ja) |
| TW (1) | TW531538B (ja) |
| UA (1) | UA58542C2 (ja) |
| WO (1) | WO1998038189A1 (ja) |
| ZA (1) | ZA981579B (ja) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2787328A1 (fr) | 1998-12-22 | 2000-06-23 | Sanofi Sa | Utilisation d'un antagoniste des recepteurs 5ht2a pour la preparation de medicaments utiles dans le traitement des ronflements et du syndrome de haute resistance ou de resistance des voies aeriennes superieures |
| TR200101939T2 (tr) * | 1999-01-28 | 2002-05-21 | Bristol-Myers Squibb Company | Antidepresan heterosiklik bileşikler |
| ES2165274B1 (es) | 1999-06-04 | 2003-04-01 | Almirall Prodesfarma Sa | Nuevos derivados de indolilpiperidina como agentes antihistaminicos y antialergicos. |
| AU5567000A (en) * | 1999-06-24 | 2001-01-09 | Toray Industries, Inc. | Alpha1b-adrenergic receptor antagonists |
| GB9928568D0 (en) * | 1999-12-03 | 2000-02-02 | Zeneca Ltd | Chemical compounds |
| GB0009803D0 (en) * | 2000-04-25 | 2000-06-07 | Astrazeneca Ab | Chemical compounds |
| ES2172436B1 (es) | 2000-10-31 | 2004-01-16 | Almirall Prodesfarma Sa | Derivados de indolilpiperidina como agentes antihistaminicos y antialergicos. |
| EP1385844B1 (en) * | 2001-04-07 | 2006-07-05 | Astrazeneca AB | Oxazolidinones containing a sulfonimid group as antibiotics |
| JPWO2004069828A1 (ja) * | 2003-02-04 | 2006-05-25 | 三菱ウェルファーマ株式会社 | ピペリジン化合物およびその医薬用途 |
| DK1691811T3 (da) | 2003-12-11 | 2014-10-20 | Sunovion Pharmaceuticals Inc | Kombination af et sedativ og en neurotransmittermodulator og fremgangsmåder til forbedring af søvnkvaliteten og behandling af depression |
| CL2008001002A1 (es) * | 2007-04-11 | 2008-10-17 | Actelion Pharmaceuticals Ltd | Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana. |
| US9505750B2 (en) * | 2007-12-18 | 2016-11-29 | Actelion Pharmaceuticals Ltd. | 5-aminocyclylmethyl-oxazolidin-2-one derivatives |
| MX2011003188A (es) * | 2008-10-10 | 2011-04-27 | Actelion Pharmaceuticals Ltd | Antibioticos de oxazolidinilo. |
| WO2014046544A1 (en) | 2012-09-21 | 2014-03-27 | Aapa B.V. | Substituted 3-heteroaryloxy-3-(hetero)aryl-propylamines as serotonin transporter and serotonin ht2c receptor modulators |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3723797A1 (de) | 1987-07-18 | 1989-01-26 | Merck Patent Gmbh | Oxazolidinone |
| DE4005371A1 (de) * | 1990-02-21 | 1991-08-22 | Merck Patent Gmbh | Oxazolidinone |
| DE4017211A1 (de) | 1990-05-29 | 1991-12-05 | Merck Patent Gmbh | Oxazolidinone |
| DK152090D0 (da) | 1990-06-22 | 1990-06-22 | Lundbaek A S H | Piperidylsubstituerede indolderivater |
| DK158590D0 (da) * | 1990-07-02 | 1990-07-02 | Lundbeck & Co As H | Indolderivater |
| DE4324393A1 (de) | 1993-07-21 | 1995-01-26 | Merck Patent Gmbh | 4-Aryloxy- und 4-Arylthiopiperidinderivate |
| DE4414113A1 (de) * | 1994-04-22 | 1995-10-26 | Merck Patent Gmbh | 3-Indolylpiperidine |
| IL114026A (en) * | 1994-06-08 | 1999-06-20 | Lundbeck & Co As H | 4-aryl-1-(indanmethyl dihydrobenzofuranmethyl or dihydrobenzo thiophenemethyl) piperidines tetrahydropyridines or piperazines and pharmaceutical compositions containing them |
| DE19500689A1 (de) * | 1995-01-12 | 1996-07-18 | Merck Patent Gmbh | Indolpiperidin-Derivate |
-
1997
- 1997-02-26 DE DE19707628A patent/DE19707628A1/de not_active Withdrawn
-
1998
- 1998-02-06 US US09/380,202 patent/US6462056B1/en not_active Expired - Fee Related
- 1998-02-06 SK SK1127-99A patent/SK112799A3/sk unknown
- 1998-02-06 AU AU63949/98A patent/AU739251B2/en not_active Ceased
- 1998-02-06 ES ES98909397T patent/ES2197466T3/es not_active Expired - Lifetime
- 1998-02-06 WO PCT/EP1998/000637 patent/WO1998038189A1/de not_active Application Discontinuation
- 1998-02-06 CA CA002281918A patent/CA2281918C/en not_active Expired - Fee Related
- 1998-02-06 CZ CZ992991A patent/CZ299199A3/cs unknown
- 1998-02-06 DK DK98909397T patent/DK0964863T3/da active
- 1998-02-06 ID IDW990813D patent/ID22838A/id unknown
- 1998-02-06 BR BR9807765-1A patent/BR9807765A/pt not_active IP Right Cessation
- 1998-02-06 PL PL98335100A patent/PL335100A1/xx unknown
- 1998-02-06 RU RU99120183/04A patent/RU2196140C2/ru not_active IP Right Cessation
- 1998-02-06 PT PT98909397T patent/PT964863E/pt unknown
- 1998-02-06 HU HU0001093A patent/HUP0001093A3/hu unknown
- 1998-02-06 AT AT98909397T patent/ATE240954T1/de not_active IP Right Cessation
- 1998-02-06 KR KR1019997007764A patent/KR20000075697A/ko not_active Application Discontinuation
- 1998-02-06 CN CNB988028344A patent/CN1177847C/zh not_active Expired - Fee Related
- 1998-02-06 EP EP98909397A patent/EP0964863B1/de not_active Expired - Lifetime
- 1998-02-06 DE DE59808461T patent/DE59808461D1/de not_active Expired - Lifetime
- 1998-02-06 JP JP53722398A patent/JP4402175B2/ja not_active Expired - Fee Related
- 1998-02-23 TW TW087102539A patent/TW531538B/zh not_active IP Right Cessation
- 1998-02-25 ZA ZA981579A patent/ZA981579B/xx unknown
- 1998-02-26 AR ARP980100858A patent/AR010899A1/es not_active Application Discontinuation
- 1998-06-02 UA UA99095309A patent/UA58542C2/uk unknown
-
1999
- 1999-08-25 NO NO19994106A patent/NO313415B1/no not_active IP Right Cessation
-
2009
- 2009-06-24 JP JP2009149274A patent/JP2009256363A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU6394998A (en) | 1998-09-18 |
| TW531538B (en) | 2003-05-11 |
| SK112799A3 (en) | 2000-06-12 |
| JP4402175B2 (ja) | 2010-01-20 |
| KR20000075697A (ko) | 2000-12-26 |
| DE19707628A1 (de) | 1998-08-27 |
| AU739251B2 (en) | 2001-10-04 |
| US6462056B1 (en) | 2002-10-08 |
| CN1177847C (zh) | 2004-12-01 |
| ID22838A (id) | 1999-12-09 |
| JP2001513764A (ja) | 2001-09-04 |
| CN1248973A (zh) | 2000-03-29 |
| AR010899A1 (es) | 2000-07-12 |
| NO994106D0 (no) | 1999-08-25 |
| PL335100A1 (en) | 2000-04-10 |
| PT964863E (pt) | 2003-10-31 |
| UA58542C2 (uk) | 2003-08-15 |
| DK0964863T3 (da) | 2003-08-04 |
| EP0964863A1 (de) | 1999-12-22 |
| CA2281918C (en) | 2007-04-03 |
| CA2281918A1 (en) | 1998-09-03 |
| DE59808461D1 (de) | 2003-06-26 |
| HUP0001093A2 (hu) | 2001-06-28 |
| BR9807765A (pt) | 2000-02-22 |
| EP0964863B1 (de) | 2003-05-21 |
| RU2196140C2 (ru) | 2003-01-10 |
| CZ299199A3 (cs) | 1999-11-17 |
| NO994106L (no) | 1999-10-19 |
| ATE240954T1 (de) | 2003-06-15 |
| ES2197466T3 (es) | 2004-01-01 |
| HUP0001093A3 (en) | 2001-07-30 |
| WO1998038189A1 (de) | 1998-09-03 |
| JP2009256363A (ja) | 2009-11-05 |
| ZA981579B (en) | 1999-03-17 |
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