NO312577B1 - Fremgangsmåte for fremstilling av en stabilisert formulering med regulert frigivelse omfattende et substrat belagt med envandig dispersjon av etylcellulose - Google Patents
Fremgangsmåte for fremstilling av en stabilisert formulering med regulert frigivelse omfattende et substrat belagt med envandig dispersjon av etylcellulose Download PDFInfo
- Publication number
- NO312577B1 NO312577B1 NO19925016A NO925016A NO312577B1 NO 312577 B1 NO312577 B1 NO 312577B1 NO 19925016 A NO19925016 A NO 19925016A NO 925016 A NO925016 A NO 925016A NO 312577 B1 NO312577 B1 NO 312577B1
- Authority
- NO
- Norway
- Prior art keywords
- agents
- ethyl cellulose
- therapeutically active
- beads
- aqueous dispersion
- Prior art date
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- 229920001249 ethyl cellulose Polymers 0.000 title claims abstract description 51
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Classifications
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- A61K9/00—Medicinal preparations characterised by special physical form
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- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
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- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Paints Or Removers (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Adhesive Tapes (AREA)
- Coating Of Shaped Articles Made Of Macromolecular Substances (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Polyurethanes Or Polyureas (AREA)
- Push-Button Switches (AREA)
- Reinforced Plastic Materials (AREA)
- Colloid Chemistry (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
- Laminated Bodies (AREA)
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US07/814,111 US5273760A (en) | 1991-12-24 | 1991-12-24 | Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer |
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US (1) | US5273760A (xx) |
EP (1) | EP0548448B1 (xx) |
JP (1) | JP3061474B2 (xx) |
KR (1) | KR100252188B1 (xx) |
AT (1) | ATE196079T1 (xx) |
AU (1) | AU652871B2 (xx) |
BR (1) | BR9202982A (xx) |
CA (1) | CA2061824C (xx) |
DE (1) | DE69231415T2 (xx) |
DK (1) | DK0548448T3 (xx) |
EG (1) | EG20083A (xx) |
ES (1) | ES2152221T3 (xx) |
FI (1) | FI921548A (xx) |
GR (1) | GR3034951T3 (xx) |
HK (1) | HK1005686A1 (xx) |
IE (1) | IE920795A1 (xx) |
IL (1) | IL101080A (xx) |
MX (1) | MX9200932A (xx) |
NO (1) | NO312577B1 (xx) |
NZ (1) | NZ241660A (xx) |
PT (1) | PT548448E (xx) |
SG (1) | SG44703A1 (xx) |
YU (1) | YU48345B (xx) |
ZA (1) | ZA921366B (xx) |
Families Citing this family (177)
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US5266331A (en) † | 1991-11-27 | 1993-11-30 | Euroceltique, S.A. | Controlled release oxycodone compositions |
US5478577A (en) * | 1993-11-23 | 1995-12-26 | Euroceltique, S.A. | Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level |
US5958459A (en) * | 1991-12-24 | 1999-09-28 | Purdue Pharma L.P. | Opioid formulations having extended controlled released |
US5681585A (en) * | 1991-12-24 | 1997-10-28 | Euro-Celtique, S.A. | Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer |
US5580578A (en) * | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
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Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60166608A (ja) * | 1984-02-08 | 1985-08-29 | Japan Atom Energy Res Inst | サンドイツチ構造をもつ徐放性複合体およびその製造方法 |
GB2170104A (en) * | 1985-01-30 | 1986-07-30 | Warner Lambert Co | Coated pharmaceutical dosage forms |
US4600645A (en) * | 1985-01-31 | 1986-07-15 | Warner-Lambert Company | Process for treating dosage forms |
GB8519310D0 (en) * | 1985-07-31 | 1985-09-04 | Zyma Sa | Granular active substances |
US5068110A (en) * | 1987-09-29 | 1991-11-26 | Warner-Lambert Company | Stabilization of enteric coated dosage form |
US5019397A (en) * | 1988-04-21 | 1991-05-28 | Alza Corporation | Aqueous emulsion for pharmaceutical dosage form |
US5042842A (en) * | 1990-06-26 | 1991-08-27 | Avery International Corporation | High security label |
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1991
- 1991-12-24 US US07/814,111 patent/US5273760A/en not_active Expired - Lifetime
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1992
- 1992-02-19 NZ NZ241660A patent/NZ241660A/xx not_active IP Right Cessation
- 1992-02-25 CA CA002061824A patent/CA2061824C/en not_active Expired - Lifetime
- 1992-02-25 ZA ZA921366A patent/ZA921366B/xx unknown
- 1992-02-27 IL IL10108092A patent/IL101080A/en not_active IP Right Cessation
- 1992-03-04 MX MX9200932A patent/MX9200932A/es unknown
- 1992-03-12 IE IE079592A patent/IE920795A1/en not_active IP Right Cessation
- 1992-03-30 JP JP4071808A patent/JP3061474B2/ja not_active Expired - Fee Related
- 1992-04-08 FI FI921548A patent/FI921548A/fi not_active Application Discontinuation
- 1992-04-15 ES ES92106519T patent/ES2152221T3/es not_active Expired - Lifetime
- 1992-04-15 DK DK92106519T patent/DK0548448T3/da active
- 1992-04-15 SG SG1996005933A patent/SG44703A1/en unknown
- 1992-04-15 EP EP92106519A patent/EP0548448B1/en not_active Expired - Lifetime
- 1992-04-15 DE DE69231415T patent/DE69231415T2/de not_active Expired - Lifetime
- 1992-04-15 AT AT92106519T patent/ATE196079T1/de active
- 1992-04-15 PT PT92106519T patent/PT548448E/pt unknown
- 1992-04-22 YU YU42792A patent/YU48345B/sh unknown
- 1992-06-15 KR KR1019920010356A patent/KR100252188B1/ko not_active IP Right Cessation
- 1992-07-31 BR BR929202982A patent/BR9202982A/pt not_active IP Right Cessation
- 1992-12-08 AU AU30024/92A patent/AU652871B2/en not_active Revoked
- 1992-12-23 EG EG80192A patent/EG20083A/xx active
- 1992-12-23 NO NO19925016A patent/NO312577B1/no not_active IP Right Cessation
-
1998
- 1998-06-04 HK HK98104870A patent/HK1005686A1/xx not_active IP Right Cessation
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2000
- 2000-11-30 GR GR20000402654T patent/GR3034951T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE69231415D1 (de) | 2000-10-12 |
IE920795A1 (en) | 1993-06-30 |
CA2061824C (en) | 1999-04-06 |
MX9200932A (es) | 1993-06-01 |
ATE196079T1 (de) | 2000-09-15 |
IL101080A0 (en) | 1992-11-15 |
YU48345B (sh) | 1998-07-10 |
HK1005686A1 (en) | 1999-01-22 |
GR3034951T3 (en) | 2001-02-28 |
NO925016D0 (no) | 1992-12-23 |
KR100252188B1 (ko) | 2000-05-01 |
EP0548448A1 (en) | 1993-06-30 |
PT548448E (pt) | 2001-03-30 |
SG44703A1 (en) | 1997-12-19 |
JP3061474B2 (ja) | 2000-07-10 |
IL101080A (en) | 1996-12-05 |
EP0548448B1 (en) | 2000-09-06 |
US5273760A (en) | 1993-12-28 |
YU42792A (sh) | 1994-09-09 |
EG20083A (en) | 1997-05-31 |
NZ241660A (en) | 1993-05-26 |
CA2061824A1 (en) | 1993-06-25 |
KR930012006A (ko) | 1993-07-20 |
NO925016L (no) | 1993-06-25 |
DE69231415T2 (de) | 2001-03-29 |
DK0548448T3 (da) | 2001-01-22 |
ZA921366B (en) | 1992-12-30 |
AU652871B2 (en) | 1994-09-08 |
FI921548A (fi) | 1993-06-25 |
JPH07165609A (ja) | 1995-06-27 |
FI921548A0 (fi) | 1992-04-08 |
BR9202982A (pt) | 1993-06-29 |
AU3002492A (en) | 1993-07-01 |
ES2152221T3 (es) | 2001-02-01 |
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