NO307752B1 - Nye hydroksimsyrederivater, farmasøytiske preparater inneholdende disse, og mellomprodukter for fremstilling derav - Google Patents
Nye hydroksimsyrederivater, farmasøytiske preparater inneholdende disse, og mellomprodukter for fremstilling deravInfo
- Publication number
- NO307752B1 NO307752B1 NO964677A NO964677A NO307752B1 NO 307752 B1 NO307752 B1 NO 307752B1 NO 964677 A NO964677 A NO 964677A NO 964677 A NO964677 A NO 964677A NO 307752 B1 NO307752 B1 NO 307752B1
- Authority
- NO
- Norway
- Prior art keywords
- group
- formula
- compounds
- pct
- date nov
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/02—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
- C07C259/18—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Vascular Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Urology & Nephrology (AREA)
- Pharmacology & Pharmacy (AREA)
- Cardiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU9401488A HU219916B (hu) | 1989-12-22 | 1994-05-06 | Hidroximsav-származékok, eljárás előállításukra és az azokat tartalmazó gyógyszerkészítmények, valamint egyes intermedierjeik |
| PCT/HU1995/000014 WO1995030649A1 (en) | 1994-05-06 | 1995-05-04 | Novel hydroximic acid derivatives, pharmaceutical compositions containing them and process for preparing same |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO964677L NO964677L (no) | 1996-11-05 |
| NO964677D0 NO964677D0 (no) | 1996-11-05 |
| NO307752B1 true NO307752B1 (no) | 2000-05-22 |
Family
ID=10985174
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO964677A NO307752B1 (no) | 1994-05-06 | 1996-11-05 | Nye hydroksimsyrederivater, farmasøytiske preparater inneholdende disse, og mellomprodukter for fremstilling derav |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US5919796A (cs) |
| EP (1) | EP0758315B1 (cs) |
| JP (1) | JP3877762B2 (cs) |
| KR (1) | KR100372312B1 (cs) |
| CN (1) | CN1079789C (cs) |
| AT (1) | ATE170170T1 (cs) |
| BG (1) | BG63336B1 (cs) |
| BR (1) | BR9507619A (cs) |
| CZ (1) | CZ288824B6 (cs) |
| DE (1) | DE69504329T2 (cs) |
| DK (1) | DK0758315T3 (cs) |
| EE (1) | EE03296B1 (cs) |
| ES (1) | ES2123252T3 (cs) |
| FI (1) | FI964436A7 (cs) |
| MX (1) | MX9605376A (cs) |
| NO (1) | NO307752B1 (cs) |
| NZ (1) | NZ285151A (cs) |
| PL (1) | PL179032B1 (cs) |
| RO (1) | RO115873B1 (cs) |
| SK (1) | SK281387B6 (cs) |
| WO (1) | WO1995030649A1 (cs) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU9502843D0 (en) * | 1995-09-29 | 1995-11-28 | Livigene Ltd | Pharmaceutical composition |
| HU222994B1 (hu) | 1995-11-02 | 2004-01-28 | BIOREX Kutató és Fejlesztő Rt. | Hidroxilaminszármazékok és azok alkalmazása sejtek molekuláris chaperon-termelésének fokozására alkalmas gyógyszerkészítmények előállítására |
| UA64716C2 (en) * | 1996-08-09 | 2004-03-15 | Pharmaceuticals for therapy or prevention of illnesses connected with dysfunction of vascular endothelial cells | |
| HUP9602204D0 (en) * | 1996-08-09 | 1996-10-28 | Biorex Rt | Pharmaceutical compositions for treating diseases connected with the disfunction of the vascular endothelial cells |
| NZ533795A (en) * | 2002-01-11 | 2006-03-31 | Biorex Kutato Fejlesztoe Kft | Carboxamidine derivatives and their use in the treatment of vascular diseases |
| BR0302750A (pt) * | 2003-08-08 | 2005-03-29 | Catarinense S A Lab | Uso de produto compreendendo material vegetal das espécies trichilia sp. associada ou não para a reversão/combate da fibrilação ventricular; composição farmacêutica compreendendo o referido material vegetal para a reversão/combate da fibrilação ventricular; método para a reversão/combate da fibrilação ventricular usando o referido material vegetal; uso do referido material vegetal para a produção de uma composição farmacêutica para a reversão/combate da fibrilação ventricular |
| HUP0303584A3 (en) | 2003-10-30 | 2009-12-28 | Cytrx Corp | Use of a hydroximic acid halide derivative in the treatment of neurodegenerative diseases |
| WO2008039514A1 (en) * | 2006-09-26 | 2008-04-03 | Cytrx Corporation | Pharmaceutical compositions and methods for treating diseases associated with neurodegeneration |
| MX2009005798A (es) * | 2006-12-01 | 2009-08-12 | Cytrx Corp | Recuperacion de apoplejia. |
| WO2022106614A1 (en) | 2020-11-19 | 2022-05-27 | Orphazyme A/S | Processes for preparing arimoclomol citrate and intermediates thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1110460B (it) * | 1977-03-02 | 1985-12-23 | Ciba Geigy Ag | Prodotti che favoriscono la crescita delle piante e prodotti che proteggono le piante a base di eteri di ossime e di esteri di ossime loro preparazione e loro impiego |
| JPS608253A (ja) * | 1983-06-28 | 1985-01-17 | Showa Denko Kk | ヒドロキシイミノブタノン誘導体及び殺虫剤 |
| HU207988B (en) * | 1988-10-20 | 1993-07-28 | Biorex Kutato Fejlesztoe Kft | Process for producing halogenides of o-/3-amino-2-hydroxy-propyl/hydroximic acid and pharmaceutical compositions containing them as active components |
| JPH068253A (ja) * | 1992-06-29 | 1994-01-18 | Kobe Steel Ltd | プラスチック成形品用金型およびその製造方法 |
-
1995
- 1995-05-04 ES ES95918106T patent/ES2123252T3/es not_active Expired - Lifetime
- 1995-05-04 CZ CZ19963251A patent/CZ288824B6/cs not_active IP Right Cessation
- 1995-05-04 RO RO96-02093A patent/RO115873B1/ro unknown
- 1995-05-04 PL PL95317154A patent/PL179032B1/pl not_active IP Right Cessation
- 1995-05-04 KR KR1019960706277A patent/KR100372312B1/ko not_active Expired - Fee Related
- 1995-05-04 EE EE9600137A patent/EE03296B1/xx not_active IP Right Cessation
- 1995-05-04 US US08/737,168 patent/US5919796A/en not_active Expired - Fee Related
- 1995-05-04 EP EP95918106A patent/EP0758315B1/en not_active Expired - Lifetime
- 1995-05-04 NZ NZ285151A patent/NZ285151A/en not_active IP Right Cessation
- 1995-05-04 JP JP52879995A patent/JP3877762B2/ja not_active Expired - Fee Related
- 1995-05-04 AT AT95918106T patent/ATE170170T1/de not_active IP Right Cessation
- 1995-05-04 SK SK1430-96A patent/SK281387B6/sk not_active IP Right Cessation
- 1995-05-04 BR BR9507619A patent/BR9507619A/pt not_active IP Right Cessation
- 1995-05-04 MX MX9605376A patent/MX9605376A/es not_active IP Right Cessation
- 1995-05-04 WO PCT/HU1995/000014 patent/WO1995030649A1/en not_active Ceased
- 1995-05-04 DK DK95918106T patent/DK0758315T3/da active
- 1995-05-04 CN CN95193977A patent/CN1079789C/zh not_active Expired - Fee Related
- 1995-05-04 DE DE69504329T patent/DE69504329T2/de not_active Expired - Fee Related
-
1996
- 1996-11-04 BG BG100954A patent/BG63336B1/bg unknown
- 1996-11-05 FI FI964436A patent/FI964436A7/fi not_active Application Discontinuation
- 1996-11-05 NO NO964677A patent/NO307752B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BG100954A (bg) | 1997-08-29 |
| SK143096A3 (en) | 1997-06-04 |
| PL317154A1 (en) | 1997-03-17 |
| NZ285151A (en) | 1998-09-24 |
| BG63336B1 (bg) | 2001-10-31 |
| JPH09512815A (ja) | 1997-12-22 |
| NO964677L (no) | 1996-11-05 |
| EE03296B1 (et) | 2000-10-16 |
| EP0758315A1 (en) | 1997-02-19 |
| DE69504329T2 (de) | 1999-04-08 |
| EP0758315B1 (en) | 1998-08-26 |
| KR100372312B1 (ko) | 2003-05-09 |
| CZ325196A3 (en) | 1997-06-11 |
| JP3877762B2 (ja) | 2007-02-07 |
| DE69504329D1 (de) | 1998-10-01 |
| AU691284B2 (en) | 1998-05-14 |
| NO964677D0 (no) | 1996-11-05 |
| US5919796A (en) | 1999-07-06 |
| CZ288824B6 (cs) | 2001-09-12 |
| MX9605376A (es) | 1998-05-31 |
| CN1151728A (zh) | 1997-06-11 |
| BR9507619A (pt) | 1997-09-23 |
| WO1995030649A1 (en) | 1995-11-16 |
| ATE170170T1 (de) | 1998-09-15 |
| FI964436A7 (fi) | 1996-11-27 |
| ES2123252T3 (es) | 1999-01-01 |
| CN1079789C (zh) | 2002-02-27 |
| RO115873B1 (ro) | 2000-07-28 |
| PL179032B1 (pl) | 2000-07-31 |
| DK0758315T3 (da) | 1999-05-25 |
| AU2416195A (en) | 1995-11-29 |
| FI964436A0 (fi) | 1996-11-05 |
| SK281387B6 (sk) | 2001-03-12 |
| KR970702845A (ko) | 1997-06-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2219894T3 (es) | Derivados heterociclicos que inhiben el factor xa. | |
| YU155290A (sh) | Dusikove spojine | |
| AU599746B2 (en) | Pyridine-2,4- and -2,5-dicarboxylic acid amides, processes for their preparation, the use thereof, and medicaments based on these compounds | |
| DK289888A (da) | 2-substitueret-e-kondenserede oe1,2,4,aatriazolooe1,5-caapyrimidiner, farmaceutiske praeparater og anvendelser deraf | |
| NO985864L (no) | Nye anti-virale forbindelser | |
| NO307752B1 (no) | Nye hydroksimsyrederivater, farmasøytiske preparater inneholdende disse, og mellomprodukter for fremstilling derav | |
| DE69231422D1 (de) | Pyridoncarbonsäurederivate | |
| ATE182331T1 (de) | Oxazolidone derivative als monoamine- oxidaseinhibitoren | |
| DE69814800D1 (de) | Epoxysuccinamid-derivate oder ihre salze | |
| EA200000389A3 (ru) | Новые замещенные пиридины или пиперидины, способ их получения и содержащие их фармацевтические композиции | |
| NO995594L (no) | Nye substituerte heterocykliske forbindelser, fremgangsmåte ved deres fremstilling og farmasoeytiske sammensetninger inneholdende dem | |
| AU601946B2 (en) | 1,4-dihydropyridine derivatives useful for the treatment of cardiovascular disorders | |
| NO980788L (no) | Immunosuppressant | |
| NO159927C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive aromatiske aminoacetylener. | |
| DK0832079T3 (da) | Antiiskæmiske hydroxylaminderivater og farmaceutiske sammensætninger | |
| CA2189652A1 (en) | Novel hydroximic acid derivatives, pharmaceutical compositions containing them and process for preparing same | |
| US5672614A (en) | Pharmaceutical use of pyridine-2,4- and -2,5-dicarboxylic acid amides | |
| FR2823749B1 (fr) | Phenyl- et pyridyl-piperidines, procede pour leur preparation et compositions pharmaceutiques les contenant | |
| DE19851299A1 (de) | Tryptase-Inhibitoren |