NO980788L - Immunosuppressant - Google Patents

Immunosuppressant

Info

Publication number
NO980788L
NO980788L NO980788A NO980788A NO980788L NO 980788 L NO980788 L NO 980788L NO 980788 A NO980788 A NO 980788A NO 980788 A NO980788 A NO 980788A NO 980788 L NO980788 L NO 980788L
Authority
NO
Norway
Prior art keywords
immunosuppressant
formula
optionally
group
atom
Prior art date
Application number
NO980788A
Other languages
English (en)
Other versions
NO980788D0 (no
Inventor
Haruhiko Makino
Yoshikazu Ohta
Takashi Sohda
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of NO980788D0 publication Critical patent/NO980788D0/no
Publication of NO980788L publication Critical patent/NO980788L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

En immunosuppressant inneholdende som aktiv ingrediens en forbindelse representert ved formel(I): hvor Y er et nitrogenatom eller C-G (G er en eventuelt esterifisert eller amidert karbok- sylgruppe, en acylgruppe, en eventuelt beskyttet hydroksyalkylgruppe eller et halogen- atom); R er en eventuelt substituert hydrokarbonrest eller en eventuelt substituert heterocyklisk gruppe; X er et oksygenatom eller et eventuelt oksydert svovelatom; n er O eller l; k er O eller l; G og R kan binde seg sammen for å danne en ring; ringene A og B kan hver ha en substituent; eller et farmasøytisk salt derav. Det blir dessuten beskrevet en farmasøytisk sammensetning som omfatter en forbindelse representert ved formel (I) ovenfor eller et farmasøytisk akseptabelt salt derav og en immunosuppressant som er forskjellig fra forbindelsen med formel (I) ovenfor, og som er nyttig som en immunosuppressant.
NO980788A 1995-09-13 1998-02-25 Immunosuppressant NO980788L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP23570495 1995-09-13
PCT/JP1996/001693 WO1997009984A1 (en) 1995-09-13 1996-06-19 Immunosuppressant

Publications (2)

Publication Number Publication Date
NO980788D0 NO980788D0 (no) 1998-02-25
NO980788L true NO980788L (no) 1998-03-31

Family

ID=16990000

Family Applications (1)

Application Number Title Priority Date Filing Date
NO980788A NO980788L (no) 1995-09-13 1998-02-25 Immunosuppressant

Country Status (10)

Country Link
EP (1) EP0850061A1 (no)
KR (1) KR19990044618A (no)
CN (1) CN1195988A (no)
AU (1) AU6137396A (no)
BR (1) BR9610314A (no)
CA (1) CA2226915A1 (no)
HU (1) HUP9900169A2 (no)
NO (1) NO980788L (no)
NZ (1) NZ310561A (no)
WO (1) WO1997009984A1 (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0941987A1 (de) * 1998-03-13 1999-09-15 Lonza A.G. Verfahren zur Herstellung von 2-Amino-4,5,3',4'-tetramethoxybenzophenon
EP1277740A1 (en) * 1998-06-12 2003-01-22 Vertex Pharmaceuticals Incorporated Inhibitors of p38
WO1999064400A1 (en) * 1998-06-12 1999-12-16 Vertex Pharmaceuticals Incorporated INHIBITORS OF p38
DE19853487A1 (de) 1998-11-19 2000-05-25 Fumapharm Ag Muri Verwendung von Dialkylfumaraten
EP1663197B1 (en) 2003-09-09 2007-12-05 Fumapharm AG The use of fumaric acid derivatives for treating cardiac insufficiency, and asthma
HRP20220902T3 (hr) 2007-02-08 2022-10-14 Biogen Ma Inc. Pripravci i njihova upotreba u liječenju multiple skleroze
CN102050780B (zh) * 2010-11-18 2012-05-02 中国科学院昆明植物研究所 喹啉衍生物,其药物组合物及其用途
WO2017151947A1 (en) * 2016-03-02 2017-09-08 George Robert Pettit 4-azapodophylotoxins compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0138654B1 (ko) * 1987-08-26 1998-04-30 프레드릭 에이. 유스티스, 3세 인터루킨-i 저해제 및 이의 제조방법
KR0148009B1 (ko) * 1988-05-27 1998-08-01 그래고리 비. 아보트 인터루킨-1 억제제
JP2863265B2 (ja) * 1989-05-19 1999-03-03 ハダサ メディカル オーガニゼーション インターロイキン１インヒビター
US6238875B1 (en) * 1991-03-12 2001-05-29 The Scripps Research Institute Diagnostic methods useful in the characterization of lymphoproliferative disease characterized by increased EPR-1
TW232013B (no) * 1992-04-24 1994-10-11 Takeda Pharm Industry Co Ltd
US5646154A (en) * 1992-10-07 1997-07-08 Sumitomo Pharmaceuticals Co., Ltd. Pharmaceutical compositions for inhibiting the formation of tumor necrosis factor
JPH06340658A (ja) * 1993-04-08 1994-12-13 Kyowa Hakko Kogyo Co Ltd ベンゾイミダゾール誘導体
IL111743A0 (en) * 1993-12-08 1995-01-24 Intermune Life Sciences Inc Recombinant genes expressing pp14

Also Published As

Publication number Publication date
BR9610314A (pt) 1999-07-06
CA2226915A1 (en) 1997-03-20
NZ310561A (en) 1999-07-29
KR19990044618A (ko) 1999-06-25
AU6137396A (en) 1997-04-01
HUP9900169A2 (hu) 2000-03-28
EP0850061A1 (en) 1998-07-01
WO1997009984A1 (en) 1997-03-20
CN1195988A (zh) 1998-10-14
NO980788D0 (no) 1998-02-25

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application