NO305949B1 - 20-metylsubstituerte vitamin D-derivater, farmasoeytiske preparater inneholdende disse, og anvendelse derav - Google Patents

20-metylsubstituerte vitamin D-derivater, farmasoeytiske preparater inneholdende disse, og anvendelse derav

Info

Publication number
NO305949B1
NO305949B1 NO942178A NO942178A NO305949B1 NO 305949 B1 NO305949 B1 NO 305949B1 NO 942178 A NO942178 A NO 942178A NO 942178 A NO942178 A NO 942178A NO 305949 B1 NO305949 B1 NO 305949B1
Authority
NO
Norway
Prior art keywords
group
derivatives
methyl
carbon atoms
production
Prior art date
Application number
NO942178A
Other languages
English (en)
Norwegian (no)
Other versions
NO942178D0 (no
NO942178L (cs
Inventor
Guenter Neef
Andreas Steinmeyer
Gerald Kirsch
Katica Schwarz
Ruth Thieroff-Ekerdt
Herbert Wiesinger
Martin Haberey
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO942178D0 publication Critical patent/NO942178D0/no
Publication of NO942178L publication Critical patent/NO942178L/no
Publication of NO305949B1 publication Critical patent/NO305949B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO942178A 1991-12-13 1994-06-10 20-metylsubstituerte vitamin D-derivater, farmasoeytiske preparater inneholdende disse, og anvendelse derav NO305949B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4141746A DE4141746A1 (de) 1991-12-13 1991-12-13 20-methyl-substituierte vitamin d-derivate
PCT/EP1992/002887 WO1993012081A1 (de) 1991-12-13 1992-12-14 20-methyl-substituierte vitamin d-derivate

Publications (3)

Publication Number Publication Date
NO942178D0 NO942178D0 (no) 1994-06-10
NO942178L NO942178L (cs) 1994-06-10
NO305949B1 true NO305949B1 (no) 1999-08-23

Family

ID=6447341

Family Applications (1)

Application Number Title Priority Date Filing Date
NO942178A NO305949B1 (no) 1991-12-13 1994-06-10 20-metylsubstituerte vitamin D-derivater, farmasoeytiske preparater inneholdende disse, og anvendelse derav

Country Status (24)

Country Link
US (1) US5446035A (cs)
EP (1) EP0637299B1 (cs)
JP (1) JP3280975B2 (cs)
KR (1) KR100271462B1 (cs)
CN (1) CN1035177C (cs)
AT (1) ATE138366T1 (cs)
AU (1) AU670585B2 (cs)
CA (1) CA2125476C (cs)
CZ (1) CZ286579B6 (cs)
DE (2) DE4141746A1 (cs)
DK (1) DK0637299T3 (cs)
ES (1) ES2089585T3 (cs)
FI (1) FI108226B (cs)
GR (1) GR3020097T3 (cs)
HU (1) HUT68263A (cs)
IL (1) IL104074A (cs)
MX (1) MX9207101A (cs)
NO (1) NO305949B1 (cs)
NZ (1) NZ246052A (cs)
PL (1) PL171403B1 (cs)
SK (1) SK280450B6 (cs)
TW (1) TW275060B (cs)
WO (1) WO1993012081A1 (cs)
ZA (1) ZA929650B (cs)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4220757A1 (de) * 1992-06-24 1994-01-05 Schering Ag Derivate in der Vitamin D-Reihe mit Modifikationen in der 20-Position, Verfahren zu ihrer Herstellung, Zwischenprodukte für dieses Verfahren, diese Derivate enthaltende pharmazeutische Präparate sowie deren Verwendung zur Herstellung von Arzneimitteln
GB9220272D0 (en) * 1992-09-25 1992-11-11 Leo Pharm Prod Ltd Chemical compounds
IL107185A (en) * 1992-10-06 1998-02-22 Schering Ag Vitamin d, 25-carboxylic acid derivatives and pharmaceutical compositions containing the same
US6407082B1 (en) * 1996-09-13 2002-06-18 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of a vitamin D compound
US20040167106A1 (en) * 1993-06-04 2004-08-26 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of a Vitamin D compound
GB9315253D0 (en) * 1993-07-23 1993-09-08 Res Inst Medicine Chem Chemical compounds
US5428029A (en) * 1993-11-24 1995-06-27 Hoffmann-La Roche Inc. Vitamin D3 fluorinated analogs
US5981597A (en) * 1995-02-13 1999-11-09 Trustees Of The University Of Pennsylvania Differentiating agents for the treatment of inflammatory intestinal diseases
ES2243978T3 (es) * 1996-02-13 2005-12-01 G.D. SEARLE & CO. Composiciones que comprenden un inhibidor de la ciclooxigenasa-2 y un antagonista del receptor de leucotrieno b4.
DE19619036A1 (de) 1996-04-30 1997-11-13 Schering Ag Neue Vitamin D-Derivate mit carbo- oder heterocyclischen Substituenten an C-25, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
SG70010A1 (en) * 1996-05-23 2000-01-25 Hoffmann La Roche Fluorinated vitamin d3 analogs
US6511970B1 (en) 1996-09-13 2003-01-28 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of products that induce transforming growth factor-beta and/or apoptosis in the ovarian epithelium
US6765002B2 (en) 2000-03-21 2004-07-20 Gustavo Rodriguez Prevention of ovarian cancer by administration of products that induce transforming growth factor-β and/or apoptosis in the ovarian epithelium
US6034074A (en) 1996-09-13 2000-03-07 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of a Vitamin D compound
US6028064A (en) 1996-09-13 2000-02-22 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of progestin products
CA2303248A1 (en) 1997-09-08 1999-03-18 F. Hoffmann-La Roche Ag 1,3-dihydroxy-20,20-dialkyl-vitamin d3 analogs
US6521608B1 (en) 1998-03-27 2003-02-18 Oregon Health & Science University Vitamin D and its analogs in the treatment of tumors and other hyperproliferative disorders
US6443856B1 (en) 1999-11-01 2002-09-03 Callaway Golf Company Contoured scorelines for the face of a golf club
US20030188756A1 (en) * 2002-08-19 2003-10-09 Cantorna Margherita T Treatment of inflammatory bowel disease with vitamin d compounds
US6989377B2 (en) 1999-12-21 2006-01-24 Wisconsin Alumni Research Foundation Treating vitamin D responsive diseases
US6358939B1 (en) 1999-12-21 2002-03-19 Northern Lights Pharmaceuticals, Llc Use of biologically active vitamin D compounds for the prevention and treatment of inflammatory bowel disease
US20010044431A1 (en) * 2000-03-21 2001-11-22 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
AU2001278744A1 (en) * 2000-08-17 2002-02-25 Chugai Seiyaku Kabushiki Kaisha Remedial agent for osteoporosis
TWI329105B (en) 2002-02-01 2010-08-21 Rigel Pharmaceuticals Inc 2,4-pyrimidinediamine compounds and their uses
RS53109B (en) * 2003-07-30 2014-06-30 Rigel Pharmaceuticals Inc. 2,4 PIRIMIDINDIAMINE COMPOUNDS FOR USE IN TREATMENT OR PREVENTION OF AUTOIMMUNE DISEASES
AU2006245282A1 (en) * 2005-05-10 2006-11-16 Dermipsor Ltd. Compositions and methods for skin care
EP1879595B1 (en) * 2005-05-10 2014-09-24 Dermipsor Ltd Compositions and methods for treating hyperproliferative epidermal diseases
US7576053B2 (en) 2005-06-13 2009-08-18 Rigel Pharmaceuticals, Inc. Methods and compositions for treating degenerative bone disorders
PT1734251E (pt) * 2005-06-17 2007-03-30 Magneti Marelli Powertrain Spa Injector de combustível
NZ570816A (en) * 2006-04-10 2011-07-29 Wisconsin Alumni Res Found 1alpha-hydroxy-2-(3'-hydroxypropylidene)-19-nor-vitamin D compounds with a 1,1-dimethylpropyl side chain
CA2838089A1 (en) 2006-08-25 2008-02-28 Cougar Biotechnology, Inc. Methods for treating cancer comprising the administration of a vitamin d compound and an additional therapeutic agent, and compositions containing the same
US20080051380A1 (en) * 2006-08-25 2008-02-28 Auerbach Alan H Methods and compositions for treating cancer
US20080051375A1 (en) * 2006-08-25 2008-02-28 Auerbach Alan H Methods for treating cancer comprising the administration of a vitamin d compound and an additional therapeutic agent, and compositions containing the same
US20090124587A1 (en) * 2007-07-12 2009-05-14 Auerbach Alan H METHODS FOR TREATING CANCER USING 17alpha-HYDROXYLASE/C17,20-LYASE INHIBITORS
AU2010208323B2 (en) 2009-01-27 2016-03-10 Berg Llc Vitamin D3 and analogs thereof for alleviating side effects associated with chemotherapy
CA2770683C (en) 2009-08-14 2018-09-04 Berg Biosystems, Llc Vitamin d3 and analogs thereof for treating alopecia
WO2017209934A1 (en) 2016-05-13 2017-12-07 Case Western Reserve University Autophagy activators for treating or preventing skin injury
UA124972C2 (uk) 2016-07-29 2021-12-22 Янссен Фармацевтика Нв Способи лікування раку передміхурової залози
US10548908B2 (en) * 2016-09-15 2020-02-04 Nostopharma, LLC Compositions and methods for preventing and treating heterotopic ossification and pathologic calcification
US11903952B2 (en) 2020-05-27 2024-02-20 Northwestern University Vitamin D as an immune modulator to prevent immune-related complication from COVID-19 infection

Also Published As

Publication number Publication date
FI942766A7 (fi) 1994-06-10
CA2125476C (en) 2003-02-11
JPH07505132A (ja) 1995-06-08
EP0637299B1 (de) 1996-05-22
IL104074A0 (en) 1993-05-13
ATE138366T1 (de) 1996-06-15
CN1073677A (zh) 1993-06-30
MX9207101A (es) 1993-08-01
DE4141746A1 (de) 1993-06-17
CN1035177C (zh) 1997-06-18
CZ286579B6 (cs) 2000-05-17
HU9401456D0 (en) 1994-08-29
ES2089585T3 (es) 1996-10-01
PL171403B1 (pl) 1997-04-30
AU670585B2 (en) 1996-07-25
DE59206393D1 (de) 1996-06-27
WO1993012081A1 (de) 1993-06-24
FI942766A0 (fi) 1994-06-10
CZ141694A3 (en) 1995-01-18
SK66194A3 (en) 1995-02-08
SK280450B6 (sk) 2000-02-14
EP0637299A1 (de) 1995-02-08
KR940703806A (ko) 1994-12-12
IL104074A (en) 1998-01-04
TW275060B (cs) 1996-05-01
ZA929650B (en) 1993-06-09
US5446035A (en) 1995-08-29
AU4035693A (en) 1993-07-19
KR100271462B1 (ko) 2000-11-15
JP3280975B2 (ja) 2002-05-13
GR3020097T3 (en) 1996-08-31
DK0637299T3 (da) 1996-09-30
HUT68263A (en) 1995-06-28
NO942178D0 (no) 1994-06-10
NZ246052A (en) 1995-07-26
FI108226B (fi) 2001-12-14
NO942178L (cs) 1994-06-10
CA2125476A1 (en) 1993-06-24

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