ES458264A1 - Procedimiento para la preparacion de nuevos compuestos ana- logos a prostaglandinas. - Google Patents

Procedimiento para la preparacion de nuevos compuestos ana- logos a prostaglandinas.

Info

Publication number
ES458264A1
ES458264A1 ES458264A ES458264A ES458264A1 ES 458264 A1 ES458264 A1 ES 458264A1 ES 458264 A ES458264 A ES 458264A ES 458264 A ES458264 A ES 458264A ES 458264 A1 ES458264 A1 ES 458264A1
Authority
ES
Spain
Prior art keywords
carbon atoms
manufacutre
pyrrolidones
hydrocarbonate
hydrocarbonate radical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES458264A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES458264A1 publication Critical patent/ES458264A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Procedimiento para la preparación de nuevos compuestos análogos a prostaglandinas de la fórmula I *** en la que R1 significa un radical hidrocarbonato alifático, de cadena recta o ramificada, saturado o insaturado, con 1-10 átomos de carbono, o un radical hidrocarbonato cicloalifático con 3-7 átomos de carbono.
ES458264A 1976-05-04 1977-04-28 Procedimiento para la preparacion de nuevos compuestos ana- logos a prostaglandinas. Expired ES458264A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762619638 DE2619638A1 (de) 1976-05-04 1976-05-04 Pyrrolidone und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
ES458264A1 true ES458264A1 (es) 1978-07-16

Family

ID=5977020

Family Applications (1)

Application Number Title Priority Date Filing Date
ES458264A Expired ES458264A1 (es) 1976-05-04 1977-04-28 Procedimiento para la preparacion de nuevos compuestos ana- logos a prostaglandinas.

Country Status (9)

Country Link
JP (1) JPS52133975A (es)
BE (1) BE854268A (es)
DE (1) DE2619638A1 (es)
DK (1) DK194377A (es)
ES (1) ES458264A1 (es)
FR (1) FR2372806A1 (es)
GB (1) GB1583163A (es)
IT (1) IT1086223B (es)
NL (1) NL7704739A (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4320136A (en) 1980-08-11 1982-03-16 E. I. Du Pont De Nemours And Company 8-Aza-16,16-difluoroprostanoids
US4321201A (en) 1980-09-22 1982-03-23 E. I. Du Pont De Nemours And Company Optically active tert-alkyl 7-(2-oxo-5-carbonyloxypyrrolidinyl) heptanoates
EP0440789A1 (de) * 1988-04-22 1991-08-14 2-i MOSKOVSKY GOSUDARSTVENNY MEDITSINSKY INSTITUT IMENI N.I. PIROGOVA Carbalkoxymethylether von lactam-1-essigsäure sowie herstellungsverfahren
GEP20043203B (en) * 1999-12-22 2004-03-25 Pfizer Prod Inc EP4 Receptor Selective Agonists in the Treatment of Osteoporosis
AU2001290250A1 (en) * 2000-09-21 2002-04-02 Ono Pharmaceutical Co. Ltd. Ep4 receptor agonists containing 8-azaprostaglandin derivatives as the active ingredient
NZ525164A (en) 2000-11-27 2005-04-29 Pfizer Prod Inc EP4 receptor selective agonists in the treatment of osteoporosis
AU2002328855B2 (en) * 2001-07-16 2005-11-24 F. Hoffmann-La Roche Ag Prostaglandin Analogues As EP4 Receptor Agonists
PT1408961E (pt) 2001-07-16 2007-10-10 Ono Pharmaceutical Co Derivados de 2-pirrolidona como agonistas de prostanóides
KR100826866B1 (ko) * 2001-07-23 2008-05-06 오노 야꾸힝 고교 가부시키가이샤 Ｅｐ４ 아고니스트를 유효 성분으로 하는 골량 저하질환의 치료제
CA2477715A1 (en) 2002-03-05 2003-09-12 Ono Pharmaceutical Co., Ltd. 8-azaprostaglandin derivative compound and agent comprising the compound as active ingredient
AU2003237520B2 (en) * 2002-06-10 2009-01-08 Laboratoires Serono Sa Gamma lactams as prostaglandin agonists and use thereof
PL378342A1 (pl) 2003-01-10 2006-03-20 F. Hoffmann-La Roche Ag Pochodne 2-piperydonu jako agoniści prostaglandyn
EP1586564B1 (en) * 2003-01-21 2012-11-28 Ono Pharmaceutical Co., Ltd. 8-azaprostaglandin derivatives and medicinal uses thereof
US7179820B2 (en) 2003-06-06 2007-02-20 Allergan, Inc. Piperidinyl prostaglandin E analogs
US7858650B2 (en) 2004-10-22 2010-12-28 Ono Pharmaceutical Co., Ltd. Medicinal composition for inhalation
CA2879507A1 (en) 2012-07-19 2014-01-23 Cayman Chemical Company, Inc. Difluorolactam compounds as ep4 receptor-selective agonists for use in the treatment of ep4-mediated disease and conditions
CA2903314C (en) 2013-03-15 2023-02-14 Cayman Chemical Company, Inc. Methods of synthesizing a difluorolactam analog
DK2989098T3 (en) * 2013-03-15 2017-08-28 Cayman Chemical Co Inc LACTAM RELATIONS AS EP4 RECEPTOR SELECTIVE AGONISTS FOR USING THE TREATMENT OF EP4-MEDIATED DISEASES AND CONDITIONS
WO2014144610A1 (en) * 2013-03-15 2014-09-18 Cayman Chemical Company, Inc. Lactam compounds as ep4 receptor-selective agonists for use in the treatment of ep4-mediated diseases and conditions
WO2015009991A2 (en) 2013-07-19 2015-01-22 Cayman Chemical Company, Inc. Methods, systems, and compositions for promoting bone growth

Also Published As

Publication number Publication date
FR2372806B1 (es) 1980-02-29
JPS52133975A (en) 1977-11-09
BE854268A (fr) 1977-11-04
FR2372806A1 (fr) 1978-06-30
GB1583163A (en) 1981-01-21
NL7704739A (nl) 1977-11-08
IT1086223B (it) 1985-05-28
DE2619638A1 (de) 1977-11-17
DK194377A (da) 1977-11-05

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