ES458264A1 - Procedimiento para la preparacion de nuevos compuestos ana- logos a prostaglandinas. - Google Patents

Procedimiento para la preparacion de nuevos compuestos ana- logos a prostaglandinas.

Info

Publication number
ES458264A1
ES458264A1 ES458264A ES458264A ES458264A1 ES 458264 A1 ES458264 A1 ES 458264A1 ES 458264 A ES458264 A ES 458264A ES 458264 A ES458264 A ES 458264A ES 458264 A1 ES458264 A1 ES 458264A1
Authority
ES
Spain
Prior art keywords
carbon atoms
manufacutre
pyrrolidones
hydrocarbonate
hydrocarbonate radical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES458264A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES458264A1 publication Critical patent/ES458264A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)

Abstract

Procedimiento para la preparación de nuevos compuestos análogos a prostaglandinas de la fórmula I *** en la que R1 significa un radical hidrocarbonato alifático, de cadena recta o ramificada, saturado o insaturado, con 1-10 átomos de carbono, o un radical hidrocarbonato cicloalifático con 3-7 átomos de carbono.
ES458264A 1976-05-04 1977-04-28 Procedimiento para la preparacion de nuevos compuestos ana- logos a prostaglandinas. Expired ES458264A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762619638 DE2619638A1 (de) 1976-05-04 1976-05-04 Pyrrolidone und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
ES458264A1 true ES458264A1 (es) 1978-07-16

Family

ID=5977020

Family Applications (1)

Application Number Title Priority Date Filing Date
ES458264A Expired ES458264A1 (es) 1976-05-04 1977-04-28 Procedimiento para la preparacion de nuevos compuestos ana- logos a prostaglandinas.

Country Status (9)

Country Link
JP (1) JPS52133975A (es)
BE (1) BE854268A (es)
DE (1) DE2619638A1 (es)
DK (1) DK194377A (es)
ES (1) ES458264A1 (es)
FR (1) FR2372806A1 (es)
GB (1) GB1583163A (es)
IT (1) IT1086223B (es)
NL (1) NL7704739A (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4320136A (en) 1980-08-11 1982-03-16 E. I. Du Pont De Nemours And Company 8-Aza-16,16-difluoroprostanoids
US4321201A (en) 1980-09-22 1982-03-23 E. I. Du Pont De Nemours And Company Optically active tert-alkyl 7-(2-oxo-5-carbonyloxypyrrolidinyl) heptanoates
US5021568A (en) * 1988-04-22 1991-06-04 Shipov Alexandr G Lactam-1-acetic acid carbalkoxymethyl esters and method for preparing same
EA005293B1 (ru) 1999-12-22 2004-12-30 Пфайзер Продактс Инк. Производные пирролидин-2-она и их применение при лечении остеопороза
WO2002024647A1 (en) * 2000-09-21 2002-03-28 Ono Pharmaceutical Co., Ltd. Ep4 receptor agonists containing 8-azaprostaglandin derivatives as the active ingredient
EP1339678B1 (en) * 2000-11-27 2007-09-26 Pfizer Products Inc. Ep4 receptor selective agonists in the treatment of osteoporosis
MXPA04000456A (es) * 2001-07-16 2004-03-18 Hoffmann La Roche Analogos de prostaglandina como agonistas del receptor ep4.
MXPA04000454A (es) 2001-07-16 2004-03-18 Hoffmann La Roche Derivados de 2-pirrolidona como agonistas de prostanoides.
NZ530885A (en) 2001-07-23 2007-09-28 Ono Pharmaceutical Co Remedies for diseases with bone mass loss having EP4 agonist as the active ingredient
EP1481976B1 (en) 2002-03-05 2012-11-07 Ono Pharmaceutical Co., Ltd. 8-azaprostaglandin derivative compounds and drugs containing the compounds as the active ingredient
EP1556347A4 (en) * 2002-06-10 2006-08-09 Applied Research Systems GAMMA LACTAME AS PROSTAGLAND INAGONISTS AND THEIR USE
RU2311409C2 (ru) 2003-01-10 2007-11-27 Ф.Хоффманн-Ля Рош Аг Производные 2-пиперидона в качестве агонистов простагландина
WO2004065365A1 (ja) * 2003-01-21 2004-08-05 Ono Pharmaceutical Co., Ltd. ８−アザプロスタグランジン誘導体およびその医薬用途
US7179820B2 (en) 2003-06-06 2007-02-20 Allergan, Inc. Piperidinyl prostaglandin E analogs
JP4893999B2 (ja) * 2004-10-22 2012-03-07 小野薬品工業株式会社 吸入用医薬組成物
EP3175852B1 (en) 2012-07-19 2019-03-06 Cayman Chemical Company, Incorporated Difluorolactam compositions for ep4-mediated osteo related diseases and conditions
AU2014229065B2 (en) 2013-03-15 2017-03-09 Cayman Chemical Company, Inc. Methods of synthesizing a difluorolactam analog
EP3235817B1 (en) * 2013-03-15 2018-12-12 Cayman Chemical Company, Incorporated Lactam compounds as ep4 receptor-selective agonists for use in the treatment of ep4-mediated diseases and conditions
US9676712B2 (en) 2013-03-15 2017-06-13 Cayman Chemical Company, Inc. Lactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions
AU2014290512A1 (en) 2013-07-19 2015-11-12 Cayman Chemical Company, Inc. Methods, systems, and compositions for promoting bone growth

Also Published As

Publication number Publication date
NL7704739A (nl) 1977-11-08
DE2619638A1 (de) 1977-11-17
IT1086223B (it) 1985-05-28
FR2372806A1 (fr) 1978-06-30
GB1583163A (en) 1981-01-21
JPS52133975A (en) 1977-11-09
BE854268A (fr) 1977-11-04
FR2372806B1 (es) 1980-02-29
DK194377A (da) 1977-11-05

Similar Documents

Publication Publication Date Title
ES458264A1 (es) Procedimiento para la preparacion de nuevos compuestos ana- logos a prostaglandinas.
ES438214A1 (es) Procedimiento continuo para la preparacion de alcoxisilanos.
JPS5245261A (en) Electronic parts
ES476452A1 (es) Un procedimiento para la produccion de una ciclohex-3-en-1- ona
ES462849A1 (es) Un procedimiento para la preparacion de nuevos derivados de 3,5-diona-4,4-dimetil-pirrolidina.
ES445263A1 (es) Un procedimiento para preparar un nuevo derivado de dimer- captoetileter.
ES445981A1 (es) Procedimiento para la preparacion de un compuesto intermedioen la sintesis de 9 alfa-halogeno-16 beta-metil-prednisolo- na.
JPS5231448A (en) Gripper
ES438725A1 (es) Un procedimiento de preparacion de derivados sustituidos del acido prostanoico.
ES459871A1 (es) Procedimiento para la obtencion de sales de hidrocarbil-tio-etilaminas.
ES464851A1 (es) Procedimiento para la preparacion de derivados de acidos 3- carboxifenilaceticos.
ES433723A1 (es) Procedimiento de obtencion de un derivado de 2-pirrolidi- nona.
JO1154B1 (en) Method for preparing 2, 3 dichlorodore-4- (2-thenol) phenolic acid
JPS5246233A (en) Carburetor
ES458806A1 (es) Un procedimiento para preparar fenilalquilaminas.
ES461637A1 (es) Un procedimiento para la preparacion de compuestos tiazoli- nil cetobenzimidazoles.
ES478050A1 (es) Procedimiento para la preparacion de 1-metil-isoguanosina.
ES452702A1 (es) Un procedimiento para la preparacion de 2-alquilamino-1-(2- tiemil)-etanoles.
ES459948A1 (es) Un procedimiento para la preparacion de alfa-mecaptopropio- nilglicinato de arginina.
FI762309A7 (es)
ES460411A2 (es) Procedimiento de preparacion de derivados arilamino-pirimi- dinicos.
JPS548642A (en) Improvement in anticorrosion of electrodeposit coating film
ES8100309A1 (es) Un procedimiento para la preparacion de 4-azo-5a-androstan-3-ona 17-sustituida.(como divisional de la patente numero 479.576)
ES437945A1 (es) Procedimiento para la obtencion de herbicidas.
ES331674A1 (es) Procedimiento para la obtencion de derivados de la benzodiacepin-2-ona.