JPS52133975A - Pyrrolidones and their preparation - Google Patents
Pyrrolidones and their preparationInfo
- Publication number
- JPS52133975A JPS52133975A JP5194577A JP5194577A JPS52133975A JP S52133975 A JPS52133975 A JP S52133975A JP 5194577 A JP5194577 A JP 5194577A JP 5194577 A JP5194577 A JP 5194577A JP S52133975 A JPS52133975 A JP S52133975A
- Authority
- JP
- Japan
- Prior art keywords
- pyrrolidones
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19762619638 DE2619638A1 (de) | 1976-05-04 | 1976-05-04 | Pyrrolidone und verfahren zu ihrer herstellung |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS52133975A true JPS52133975A (en) | 1977-11-09 |
Family
ID=5977020
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP5194577A Pending JPS52133975A (en) | 1976-05-04 | 1977-05-04 | Pyrrolidones and their preparation |
Country Status (9)
Country | Link |
---|---|
JP (1) | JPS52133975A (ja) |
BE (1) | BE854268A (ja) |
DE (1) | DE2619638A1 (ja) |
DK (1) | DK194377A (ja) |
ES (1) | ES458264A1 (ja) |
FR (1) | FR2372806A1 (ja) |
GB (1) | GB1583163A (ja) |
IT (1) | IT1086223B (ja) |
NL (1) | NL7704739A (ja) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002024647A1 (fr) * | 2000-09-21 | 2002-03-28 | Ono Pharmaceutical Co., Ltd. | Agonistes du recepteur de l'ep4 comprenant comme principe actif des derives de la 8-azaprostaglandine |
WO2003074483A1 (fr) | 2002-03-05 | 2003-09-12 | Ono Pharmaceutical Co., Ltd. | Composes derives de 8 azaprostaglandine et medicaments contenant ceux-ci comme principe actif |
JP2007197467A (ja) * | 2000-11-27 | 2007-08-09 | Pfizer Prod Inc | 骨粗鬆症治療用ep4受容体選択的アゴニスト |
JP2012111767A (ja) * | 2001-07-23 | 2012-06-14 | Ono Pharmaceut Co Ltd | Ep4アゴニストを有効成分とする骨量低下疾患の治療剤 |
JP2016516050A (ja) * | 2013-03-15 | 2016-06-02 | ケイマン ケミカル カンパニー, インコーポレーテッド | Ep4媒介性の疾病及び病態の治療に使用するためのep4受容体選択性アゴニストとしてのラクタム化合物 |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4320136A (en) | 1980-08-11 | 1982-03-16 | E. I. Du Pont De Nemours And Company | 8-Aza-16,16-difluoroprostanoids |
US4321201A (en) | 1980-09-22 | 1982-03-23 | E. I. Du Pont De Nemours And Company | Optically active tert-alkyl 7-(2-oxo-5-carbonyloxypyrrolidinyl) heptanoates |
EP0440789A1 (de) * | 1988-04-22 | 1991-08-14 | 2-i MOSKOVSKY GOSUDARSTVENNY MEDITSINSKY INSTITUT IMENI N.I. PIROGOVA | Carbalkoxymethylether von lactam-1-essigsäure sowie herstellungsverfahren |
BR0016560A (pt) * | 1999-12-22 | 2002-09-10 | Pfizer Prod Inc | Agonistas seletivos do receptor ep4 no tratamento da osteoporose |
DK1408961T3 (da) | 2001-07-16 | 2007-11-05 | Hoffmann La Roche | 2 pyrrolidon-derivater som prostanoide agonister |
MXPA04000456A (es) * | 2001-07-16 | 2004-03-18 | Hoffmann La Roche | Analogos de prostaglandina como agonistas del receptor ep4. |
US7419999B2 (en) * | 2002-06-10 | 2008-09-02 | Applied Research Systems Ars Holding N.V. | Gamma lactams as prostaglandin agonists and use thereof |
CA2511255C (en) | 2003-01-10 | 2009-04-07 | F. Hoffmann-La Roche Ag | 2-piperidone derivatives as prostaglandin agonists |
EP1586564B1 (en) * | 2003-01-21 | 2012-11-28 | Ono Pharmaceutical Co., Ltd. | 8-azaprostaglandin derivatives and medicinal uses thereof |
US7179820B2 (en) | 2003-06-06 | 2007-02-20 | Allergan, Inc. | Piperidinyl prostaglandin E analogs |
JP4893999B2 (ja) * | 2004-10-22 | 2012-03-07 | 小野薬品工業株式会社 | 吸入用医薬組成物 |
CN104640542B (zh) | 2012-07-19 | 2017-09-22 | 开曼化学股份有限公司 | 用于ep4介导的骨相关疾病和病症的二氟内酰胺组合物 |
WO2014144610A1 (en) * | 2013-03-15 | 2014-09-18 | Cayman Chemical Company, Inc. | Lactam compounds as ep4 receptor-selective agonists for use in the treatment of ep4-mediated diseases and conditions |
AU2014229065B2 (en) | 2013-03-15 | 2017-03-09 | Cayman Chemical Company, Inc. | Methods of synthesizing a difluorolactam analog |
US10729810B2 (en) | 2013-07-19 | 2020-08-04 | Cayman Chemical Company, Inc | Methods, systems, and compositions for promoting bone growth |
-
1976
- 1976-05-04 DE DE19762619638 patent/DE2619638A1/de active Pending
-
1977
- 1977-04-28 ES ES458264A patent/ES458264A1/es not_active Expired
- 1977-04-29 NL NL7704739A patent/NL7704739A/xx not_active Application Discontinuation
- 1977-05-02 IT IT23096/77A patent/IT1086223B/it active
- 1977-05-03 GB GB18427/77A patent/GB1583163A/en not_active Expired
- 1977-05-03 DK DK194377A patent/DK194377A/da unknown
- 1977-05-04 BE BE177278A patent/BE854268A/xx unknown
- 1977-05-04 FR FR7713518A patent/FR2372806A1/fr active Granted
- 1977-05-04 JP JP5194577A patent/JPS52133975A/ja active Pending
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002024647A1 (fr) * | 2000-09-21 | 2002-03-28 | Ono Pharmaceutical Co., Ltd. | Agonistes du recepteur de l'ep4 comprenant comme principe actif des derives de la 8-azaprostaglandine |
JP2007197467A (ja) * | 2000-11-27 | 2007-08-09 | Pfizer Prod Inc | 骨粗鬆症治療用ep4受容体選択的アゴニスト |
JP2012111767A (ja) * | 2001-07-23 | 2012-06-14 | Ono Pharmaceut Co Ltd | Ep4アゴニストを有効成分とする骨量低下疾患の治療剤 |
WO2003074483A1 (fr) | 2002-03-05 | 2003-09-12 | Ono Pharmaceutical Co., Ltd. | Composes derives de 8 azaprostaglandine et medicaments contenant ceux-ci comme principe actif |
JP2016516050A (ja) * | 2013-03-15 | 2016-06-02 | ケイマン ケミカル カンパニー, インコーポレーテッド | Ep4媒介性の疾病及び病態の治療に使用するためのep4受容体選択性アゴニストとしてのラクタム化合物 |
Also Published As
Publication number | Publication date |
---|---|
FR2372806B1 (ja) | 1980-02-29 |
GB1583163A (en) | 1981-01-21 |
ES458264A1 (es) | 1978-07-16 |
FR2372806A1 (fr) | 1978-06-30 |
BE854268A (fr) | 1977-11-04 |
NL7704739A (nl) | 1977-11-08 |
IT1086223B (it) | 1985-05-28 |
DE2619638A1 (de) | 1977-11-17 |
DK194377A (da) | 1977-11-05 |
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