ES8404678A1 - Un procedimiento para la preparacion de derivados de pirrolidina. - Google Patents

Un procedimiento para la preparacion de derivados de pirrolidina.

Info

Publication number
ES8404678A1
ES8404678A1 ES520820A ES520820A ES8404678A1 ES 8404678 A1 ES8404678 A1 ES 8404678A1 ES 520820 A ES520820 A ES 520820A ES 520820 A ES520820 A ES 520820A ES 8404678 A1 ES8404678 A1 ES 8404678A1
Authority
ES
Spain
Prior art keywords
hydrogen
lower rent
general formula
protective group
pyrrolidine derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES520820A
Other languages
English (en)
Other versions
ES520820A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES8404678A1 publication Critical patent/ES8404678A1/es
Publication of ES520820A0 publication Critical patent/ES520820A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE PIRROLIDINA, DE FORMULA GENERAL (I), EN LA QUE R SIGNIFICA HIDROGENO O ALQUILO INFERIOR; R SIGNIFICA HIDROGENO O ALQUILO INFERIOR; N SIGNIFICA 2, 3 O 4; Y R Y R SIGNIFICAN CADA UNO DE ELLOS HIDROGENO O ALQUILO INFERIOR, Y SUS SALES DE ADICION DE ACIDO.CONSISTE EN DISOCIAR EL GRUPO PROTECTOR DESIGNADO CON Z DE UN COMPUESTO DE FORMULA GENERAL (I), EN LA QYE R Y R TIENEN EL SIGNIFICADO YA INDICADO; Y Z SIGNIFICA UN GRUPO PROTECTOR. OPCIONALMENTE SE PUEDE SEPARAR DE LA MEZCLA DE DIASTEREOISOMEROS OBTENIDA,LOS RACEMATOS CORRESPONDIENTES.DE APLICACION EN MEDICINA POR SUS PROPIEDADES FARMACODINAMICAS.
ES520820A 1981-07-24 1983-03-22 Un procedimiento para la preparacion de derivados de pirrolidina. Granted ES520820A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH4849/81A CH647234A5 (en) 1981-07-24 1981-07-24 Pyrrolidine derivatives

Publications (2)

Publication Number Publication Date
ES8404678A1 true ES8404678A1 (es) 1984-05-16
ES520820A0 ES520820A0 (es) 1984-05-16

Family

ID=4283624

Family Applications (1)

Application Number Title Priority Date Filing Date
ES520820A Granted ES520820A0 (es) 1981-07-24 1983-03-22 Un procedimiento para la preparacion de derivados de pirrolidina.

Country Status (10)

Country Link
JP (1) JPS5824558A (es)
KR (1) KR890000768B1 (es)
BR (1) BR8204328A (es)
CH (1) CH647234A5 (es)
ES (1) ES520820A0 (es)
GR (1) GR76177B (es)
IS (1) IS2742A7 (es)
MW (1) MW2682A1 (es)
PL (1) PL138918B1 (es)
ZA (1) ZA825104B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH666891A5 (de) * 1985-11-26 1988-08-31 Lonza Ag 4-alkoxy-2-oxo-pyrrolidin-1-yl-essigsaeure-c(1)-c(4)-alkylester, deren herstellung und verwendung.
KR100498268B1 (ko) * 1997-12-09 2005-11-01 주식회사 엘지생활건강 피롤리돈계 양쪽성 계면활성제

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2923975A1 (de) * 1979-06-13 1980-12-18 Nattermann A & Cie Pyrrolidinone, verfahren zu deren herstellung und diese enthaltende arzneimittel

Also Published As

Publication number Publication date
JPS5824558A (ja) 1983-02-14
JPH0345064B2 (es) 1991-07-09
KR890000768B1 (ko) 1989-04-05
PL138918B1 (en) 1986-11-29
MW2682A1 (en) 1984-03-14
KR840000489A (ko) 1984-02-22
BR8204328A (pt) 1983-07-19
GR76177B (es) 1984-08-03
ES520820A0 (es) 1984-05-16
ZA825104B (en) 1983-04-27
IS2742A7 (is) 1983-01-25
CH647234A5 (en) 1985-01-15
PL237634A1 (en) 1984-01-30

Similar Documents

Publication Publication Date Title
ES8103088A1 (es) Metodo para preparar nuevas espiro(dihidrobenzofuran-piperi-dinas y -pirrolidinas)
ZA858456B (en) Polypeptide
ES8700661A1 (es) Un procedimiento para preparar derivados de pirimidina
ES2007177A6 (es) Procedimiento para preparar amidas y tioamidas del acido 1'-desoxi-1'-(6-amino-9-purinil)-b-d-ribofuranuronico sustituidas en la posicion 2.
ZA858169B (en) New adamantanamine derivatives,processes for their preparation and drugs in which they are present
ATE48835T1 (de) Chinolylglycinamidderivate, verfahren zu ihrer herstellung und therapeutische verwendung als psychotrope.
ES393022A1 (es) Procedimiento para la preparacion de derivados de acidos adenosin-5'-carboxilicos.
ES2021515A6 (es) Procedimiento para la preparacion de compuestos derivados de isotiazolo-piridona azetidinil substituidos.
ES8404678A1 (es) Un procedimiento para la preparacion de derivados de pirrolidina.
GR76886B (es)
ES470383A1 (es) Un metodo de preparacion de un derivado de 9-hidroxietoxime-til-guanina
ES434823A1 (es) Procedimiento para preparar derivados de 1,3-difenil-propanona-1.
ES8403442A1 (es) Un procedimiento de preparacion de 1-2(arilmetil)aril-4-oxociclohexanol-oximas.
CH612907A5 (en) Process for the preparation of a new 1-aryloxy-4-amino-2-butanol
ES439180A1 (es) Procedimiento para la preparacion de derivados de piperido- na.
ES461846A2 (es) Un procedimiento para la preparacion de acidos carboxilicos alfa-cetonicos.
ES8202338A1 (es) Procedimiento para la preparacion de nuevos derivados de 1- (4-aminopiperidino)-3,4-dihidroisoquinoleina
ES8307790A1 (es) Un procedimiento para preparacion de 3-(2-(4-piperidil)-1-alquiletil) indoles.
ES8302005A1 (es) Procedimiento para preparar compuestos cefalosporanicos
ES457552A1 (es) Procedimiento para la preparacion de aminoalcoxi-cicloalca- nos.
ES420518A2 (es) Un procedimiento para la preparacion de derivados de imida-zolio.
ES8101555A1 (es) Procedimiento para preparar derivados sustituidos de adaman-tano
ES403886A1 (es) Procedimiento de preparacion de amidas del acido (trimetoxi-3,4,5)cinemico.
ES457089A1 (es) Procedimiento para la preparacion de nuevos colorantes basi-cos de antraquinona.
ES8205773A1 (es) Procedimiento para la obtencion de 2(1h)-piridinonas