NO305562B1 - FremgangsmÕte for fremstilling av en plasminogenanalog, syntetisk eller rekombinant nukleinsyre som koder for den, vektorer som omfatter en slik nukleinsyresekvens, samt celler eller cellelinjer som kan fremstille plasminogenanalogen - Google Patents

FremgangsmÕte for fremstilling av en plasminogenanalog, syntetisk eller rekombinant nukleinsyre som koder for den, vektorer som omfatter en slik nukleinsyresekvens, samt celler eller cellelinjer som kan fremstille plasminogenanalogen Download PDF

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Publication number
NO305562B1
NO305562B1 NO922238A NO922238A NO305562B1 NO 305562 B1 NO305562 B1 NO 305562B1 NO 922238 A NO922238 A NO 922238A NO 922238 A NO922238 A NO 922238A NO 305562 B1 NO305562 B1 NO 305562B1
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Prior art keywords
plasminogen
thrombin
factor
nucleic acid
sequence
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NO922238A
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English (en)
Norwegian (no)
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NO922238D0 (no
NO922238L (no
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Keith Martyn Dawson
Richard Mark Edwards
Joan Mabel Forman
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British Biotech Pharm
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Application filed by British Biotech Pharm filed Critical British Biotech Pharm
Publication of NO922238D0 publication Critical patent/NO922238D0/no
Publication of NO922238L publication Critical patent/NO922238L/no
Publication of NO305562B1 publication Critical patent/NO305562B1/no

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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6435—Plasmin (3.4.21.7), i.e. fibrinolysin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
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    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
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    • C12Y304/21—Serine endopeptidases (3.4.21)
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    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)
    • A—HUMAN NECESSITIES
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    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
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NO922238A 1989-12-07 1992-06-05 FremgangsmÕte for fremstilling av en plasminogenanalog, syntetisk eller rekombinant nukleinsyre som koder for den, vektorer som omfatter en slik nukleinsyresekvens, samt celler eller cellelinjer som kan fremstille plasminogenanalogen NO305562B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898927722A GB8927722D0 (en) 1989-12-07 1989-12-07 Proteins and nucleic acids
PCT/GB1990/001912 WO1991009118A2 (en) 1989-12-07 1990-12-07 Activatable fibrinolytic and anti-thrombotic proteins

Publications (3)

Publication Number Publication Date
NO922238D0 NO922238D0 (no) 1992-06-05
NO922238L NO922238L (no) 1992-08-06
NO305562B1 true NO305562B1 (no) 1999-06-21

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ID=10667597

Family Applications (2)

Application Number Title Priority Date Filing Date
NO922238A NO305562B1 (no) 1989-12-07 1992-06-05 FremgangsmÕte for fremstilling av en plasminogenanalog, syntetisk eller rekombinant nukleinsyre som koder for den, vektorer som omfatter en slik nukleinsyresekvens, samt celler eller cellelinjer som kan fremstille plasminogenanalogen
NO92922237A NO922237L (no) 1989-12-07 1992-06-05 Proteiner og nukleinsyrer

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO92922237A NO922237L (no) 1989-12-07 1992-06-05 Proteiner og nukleinsyrer

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US (2) US5637492A (de)
EP (2) EP0504241A1 (de)
JP (2) JP2851423B2 (de)
KR (2) KR100188302B1 (de)
AT (1) ATE155812T1 (de)
AU (3) AU644399B2 (de)
CA (2) CA2069085C (de)
DE (1) DE69031127T2 (de)
DK (1) DK0502968T3 (de)
ES (1) ES2106073T3 (de)
FI (2) FI922609A0 (de)
GB (1) GB8927722D0 (de)
GR (1) GR3024990T3 (de)
HU (1) HU211628A9 (de)
IE (2) IE904416A1 (de)
IL (2) IL96601A (de)
NO (2) NO305562B1 (de)
NZ (2) NZ236330A (de)
PT (2) PT96103B (de)
WO (2) WO1991009118A2 (de)
ZA (2) ZA909853B (de)

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CN1480466A (zh) * 2002-09-03 2004-03-10 �й������ž�����ҽѧ��ѧԺ����ҽ 一类溶栓抗凝双功能融合蛋白及应用
US9695251B2 (en) 2003-10-31 2017-07-04 The Regents Of The University Of California Activatable cell penetrating peptides with quenched fluorophores
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