NO305173B1 - Substituerte 3-aminokinuklidiner - Google Patents

Substituerte 3-aminokinuklidiner

Info

Publication number
NO305173B1
NO305173B1 NO934195A NO934195A NO305173B1 NO 305173 B1 NO305173 B1 NO 305173B1 NO 934195 A NO934195 A NO 934195A NO 934195 A NO934195 A NO 934195A NO 305173 B1 NO305173 B1 NO 305173B1
Authority
NO
Norway
Prior art keywords
compounds
aminoquinuclidines
substituted
disorders
antagonists
Prior art date
Application number
NO934195A
Other languages
English (en)
Norwegian (no)
Other versions
NO934195L (no
NO934195D0 (no
Inventor
Fumitaka Ito
Toshihide Kokura
Masami Nakane
Kunio Satake
Hiroaki Wakabayashi
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO934195L publication Critical patent/NO934195L/no
Publication of NO934195D0 publication Critical patent/NO934195D0/no
Publication of NO305173B1 publication Critical patent/NO305173B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicinal Preparation (AREA)
NO934195A 1991-05-22 1993-11-19 Substituerte 3-aminokinuklidiner NO305173B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP14682691 1991-05-22
PCT/US1992/004002 WO1992020676A1 (en) 1991-05-22 1992-05-19 Substituted 3-aminoquinuclidines

Publications (3)

Publication Number Publication Date
NO934195L NO934195L (no) 1993-11-19
NO934195D0 NO934195D0 (no) 1993-11-19
NO305173B1 true NO305173B1 (no) 1999-04-12

Family

ID=15416402

Family Applications (1)

Application Number Title Priority Date Filing Date
NO934195A NO305173B1 (no) 1991-05-22 1993-11-19 Substituerte 3-aminokinuklidiner

Country Status (25)

Country Link
EP (1) EP0585328B1 (hu)
KR (1) KR100246065B1 (hu)
CN (1) CN1041827C (hu)
AT (1) ATE211743T1 (hu)
AU (1) AU658898B2 (hu)
BR (1) BR9206044A (hu)
CA (1) CA2109415C (hu)
CZ (1) CZ247993A3 (hu)
DE (2) DE9290057U1 (hu)
DK (1) DK0585328T3 (hu)
EG (1) EG20218A (hu)
ES (1) ES2168260T3 (hu)
FI (1) FI935134A (hu)
HU (1) HUT65771A (hu)
IE (1) IE921662A1 (hu)
IL (1) IL101960A (hu)
MX (1) MX9202449A (hu)
NO (1) NO305173B1 (hu)
NZ (2) NZ242880A (hu)
PL (4) PL170513B1 (hu)
PT (1) PT100514B (hu)
RU (1) RU2092486C1 (hu)
UA (1) UA26401C2 (hu)
WO (1) WO1992020676A1 (hu)
ZA (1) ZA923773B (hu)

Families Citing this family (68)

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DE69213451T2 (de) * 1991-06-20 1997-01-09 Pfizer Fluoralkoxybenzylaminoderivate stickstoffhaltiger heterocyclen
JP2656702B2 (ja) * 1992-03-23 1997-09-24 ファイザー製薬株式会社 ペプチド性キヌクリジン
DK0655996T3 (da) * 1992-08-19 2001-12-27 Pfizer Substituerede benzylamino-nitrogenholdige, ikke-aromatiske, heterocykliske forbindelser
JP2656699B2 (ja) * 1992-10-21 1997-09-24 ファイザー製薬株式会社 置換ベンジルアミノキヌクリジン
US5837711A (en) * 1992-10-28 1998-11-17 Pfizer Inc. Substituted quinuclidines as substance P antagonists
JP2656700B2 (ja) * 1992-10-28 1997-09-24 ファイザー製薬株式会社 置換キヌクリジン誘導体
AU5169693A (en) * 1992-12-10 1994-07-04 Pfizer Inc. Aminomethylene substituted non-aromatic heterocycles and use as substance p antagonists
IL109646A0 (en) * 1993-05-19 1994-08-26 Pfizer Heteroatom substituted alkyl benzylamino-quinuclidines
JP2822274B2 (ja) * 1993-05-19 1998-11-11 ファイザー製薬株式会社 Ｐ物質拮抗剤としてのヘテロ原子置換アルキルベンジルアミノキヌクリジン類
US5393762A (en) * 1993-06-04 1995-02-28 Pfizer Inc. Pharmaceutical agents for treatment of emesis
EP0708771B1 (en) * 1993-07-15 1998-10-07 Pfizer Inc. Benzyloxyquinuclidines as substance p antagonists
US6083943A (en) * 1993-09-17 2000-07-04 Pfizer Inc Substituted azaheterocyclecarboxylic acid
PT719253E (pt) * 1993-09-17 2004-07-30 Pfizer Piperidinas 3-amino-5-carboxi-substituidas e pirrolidinas 3-amino-4-carboxi-substituidas como antagonistas de taquicinina
EP0653208A3 (en) * 1993-11-17 1995-10-11 Pfizer Substance P antagonists for the treatment or prevention of sunburn.
EP0659409A3 (en) * 1993-11-23 1995-08-09 Pfizer Substance P antagonists for the inhibition of angiogenesis.
EP0655246A1 (en) * 1993-11-30 1995-05-31 Pfizer Inc. Substance P antagonists for the treatment of disorders caused by helicobacter pylori or other spiral urease-positive gram-negative bacteria
FR2728169A1 (fr) 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p pour le traitement des prurits et des dysesthesies oculaires ou palpebrales
FR2728166A1 (fr) 1994-12-19 1996-06-21 Oreal Composition topique contenant un antagoniste de substance p
FR2728165A1 (fr) 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p pour le traitement des rougeurs cutanees d'origine neurogene
PE8798A1 (es) * 1995-07-17 1998-03-02 Pfizer Procedimiento de separacion de los enantiomeros del 1-azabiciclo[2.2.2] octan-3-amina, 2-(difenilmetil) -n- [[2-metoxi-5-(1-metiletil) fenil] metil]
TW458774B (en) 1995-10-20 2001-10-11 Pfizer Antiemetic pharmaceutical compositions
FR2741262B1 (fr) 1995-11-20 1999-03-05 Oreal Utilisation d'un antagoniste de tnf-alpha pour le traitement des rougeurs cutanees d'origine neurogene
MX9706944A (es) * 1996-09-12 1998-08-30 Pfizer Quinuclidinas sustituidas con tetrazolilo como antagonistas de la sustancia p.
NZ329807A (en) * 1997-04-23 2000-07-28 Pfizer NK-1 receptor antagonists and P receptor antagonists 2-Diarylmethyl-3-amino-1-azabicyclo[2.2.2]octane derivatives and amino substituted N-containing rings as agents for treating irritable bowel syndrome
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US6861526B2 (en) 2002-10-16 2005-03-01 Pfizer Inc. Process for the preparation of (S,S)-cis-2-benzhydryl-3-benzylaminoquinuclidine
KR101412339B1 (ko) 2004-07-15 2014-06-25 알바니 몰레큘라 리써치, 인크. 아릴- 및 헤테로아릴-치환된 테트라히드로이소퀴놀린, 및이것의 노르에피네프린, 도파민 및 세로토닌의 재흡수를차단하기 위한 용도
US8362075B2 (en) 2005-05-17 2013-01-29 Merck Sharp & Dohme Corp. Cyclohexyl sulphones for treatment of cancer
KR20080044840A (ko) 2005-07-15 2008-05-21 에이엠알 테크놀로지, 인크. 아릴- 및 헤테로아릴-치환된 테트라히드로벤자제핀, 및노르에피네프린, 도파민 및 세로토닌의 재흡수를 차단하기위한 용도
CN101277960A (zh) 2005-09-29 2008-10-01 默克公司 作为黑皮质素-4受体调节剂的酰化螺哌啶衍生物
GB0603041D0 (en) 2006-02-15 2006-03-29 Angeletti P Ist Richerche Bio Therapeutic compounds
CA2664113C (en) 2006-09-22 2013-05-28 Merck & Co., Inc. Use of platencin and platensimycin as fatty acid synthesis inhibitors to treat obesity, diabetes and cancer
US20110218176A1 (en) 2006-11-01 2011-09-08 Barbara Brooke Jennings-Spring Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
PL2805945T3 (pl) 2007-01-10 2019-09-30 Msd Italia S.R.L. Indazole podstawione grupą amidową jako inhibitory polimerazy poli(adp-rybozy) - (parp)
US8093268B2 (en) 2007-01-24 2012-01-10 Glaxo Group Limited Pharmaceutical compositions comprising 2-methoxy-5-(5-trifluoromethyl-tetrazol-1-yl-benzyl)-(2S-phenylpiperidin-3S-yl-)
US8106086B2 (en) 2007-04-02 2012-01-31 Msd K.K. Indoledione derivative
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US8598184B2 (en) 2008-03-03 2013-12-03 Tiger Pharmatech Protein kinase inhibitors
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
UA105182C2 (ru) 2008-07-03 2014-04-25 Ньюрексон, Інк. Бензоксазины, бензотиазины и родственные соединения, которые имеют ингибирующую nos активность
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ES2528404T3 (es) 2009-05-12 2015-02-10 Bristol-Myers Squibb Company Formas cristalinas de (S)-7-([1,2,4]triazol[1,5-a]piridin-6-il)-4-(3,4-diclorofenil)-1,2,3,4-tetrahidroisoquinolina y sus usos
UA109417C2 (uk) 2009-10-14 2015-08-25 Мерк Шарп Енд Доме Корп. ЗАМІЩЕНІ ПІПЕРИДИНИ, ЯКІ ПІДВИЩУЮТЬ АКТИВНІСТЬ p53, І ЇХ ЗАСТОСУВАННЯ
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US8518907B2 (en) 2010-08-02 2013-08-27 Merck Sharp & Dohme Corp. RNA interference mediated inhibition of catenin (cadherin-associated protein), beta 1 (CTNNB1) gene expression using short interfering nucleic acid (siNA)
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Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX18467A (es) * 1988-11-23 1993-07-01 Pfizer Agentes terapeuticos de quinuclidinas

Also Published As

Publication number Publication date
CN1068571A (zh) 1993-02-03
AU658898B2 (en) 1995-05-04
NO934195L (no) 1993-11-19
WO1992020676A1 (en) 1992-11-26
EG20218A (en) 1997-11-30
PL171921B1 (pl) 1997-06-30
DE69232334T2 (de) 2002-11-14
NO934195D0 (no) 1993-11-19
UA26401C2 (uk) 1999-08-30
FI935134A0 (fi) 1993-11-19
DK0585328T3 (da) 2002-02-11
ZA923773B (en) 1993-11-22
EP0585328B1 (en) 2002-01-09
KR100246065B1 (en) 2000-04-01
RU2092486C1 (ru) 1997-10-10
PL172069B1 (pl) 1997-07-31
FI935134A (fi) 1993-11-19
NZ272941A (en) 1997-05-26
ES2168260T3 (es) 2002-06-16
MX9202449A (es) 1993-03-01
CA2109415A1 (en) 1992-11-23
NZ242880A (en) 1995-10-26
DE69232334D1 (de) 2002-02-14
BR9206044A (pt) 1995-03-01
IL101960A (en) 1999-03-12
PT100514B (pt) 1999-06-30
HUT65771A (en) 1994-07-28
CZ247993A3 (en) 1994-07-13
PL170525B1 (en) 1996-12-31
IL101960A0 (en) 1994-04-12
CA2109415C (en) 1998-12-29
HU9303307D0 (en) 1994-03-28
AU1927592A (en) 1992-12-30
DE9290057U1 (de) 1994-01-05
PT100514A (pt) 1993-09-30
PL170513B1 (en) 1996-12-31
ATE211743T1 (de) 2002-01-15
EP0585328A1 (en) 1994-03-09
IE921662A1 (en) 1992-12-02
CN1041827C (zh) 1999-01-27

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Legal Events

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MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN NOVEMBER 2001