NO20092729L - Lipasevarianter for farmasoytisk anvendelse - Google Patents

Lipasevarianter for farmasoytisk anvendelse

Info

Publication number
NO20092729L
NO20092729L NO20092729A NO20092729A NO20092729L NO 20092729 L NO20092729 L NO 20092729L NO 20092729 A NO20092729 A NO 20092729A NO 20092729 A NO20092729 A NO 20092729A NO 20092729 L NO20092729 L NO 20092729L
Authority
NO
Norway
Prior art keywords
lipases
digestive
improved
pharmaceutical use
diabetes
Prior art date
Application number
NO20092729A
Other languages
English (en)
Norwegian (no)
Inventor
Peter-Colin Gregory
Allan Svendsen
Michael Skjot
Debbie Yaver
Lars Lehmann Hylling Christensen
Signe Eskildsen Larsen
Nina Lundin
Michael Lamsa
Original Assignee
Solvay Pharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharm Gmbh filed Critical Solvay Pharm Gmbh
Publication of NO20092729L publication Critical patent/NO20092729L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/465Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/47Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/54Mixtures of enzymes or proenzymes covered by more than a single one of groups A61K38/44 - A61K38/46 or A61K38/51 - A61K38/53
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18Carboxylic ester hydrolases (3.1.1)
    • C12N9/20Triglyceride splitting, e.g. by means of lipase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y301/00Hydrolases acting on ester bonds (3.1)
    • C12Y301/01Carboxylic ester hydrolases (3.1.1)
    • C12Y301/01003Triacylglycerol lipase (3.1.1.3)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Nutrition Science (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Detergent Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
NO20092729A 2006-12-21 2009-07-20 Lipasevarianter for farmasoytisk anvendelse NO20092729L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87119606P 2006-12-21 2006-12-21
PCT/US2007/087168 WO2008079685A2 (fr) 2006-12-21 2007-12-12 Variantes lipasiques pour une utilisation pharmaceutique

Publications (1)

Publication Number Publication Date
NO20092729L true NO20092729L (no) 2009-09-18

Family

ID=38043020

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20092729A NO20092729L (no) 2006-12-21 2009-07-20 Lipasevarianter for farmasoytisk anvendelse

Country Status (16)

Country Link
US (3) US8273348B2 (fr)
EP (6) EP2455461B1 (fr)
JP (1) JP5406040B2 (fr)
KR (1) KR20090101930A (fr)
CN (2) CN105112386A (fr)
AR (1) AR064494A1 (fr)
AU (1) AU2007337150A1 (fr)
BR (1) BRPI0721103A2 (fr)
CA (3) CA3081308C (fr)
IL (1) IL198893A0 (fr)
MX (1) MX2009006597A (fr)
NO (1) NO20092729L (fr)
RU (1) RU2009128067A (fr)
TW (1) TW200829698A (fr)
WO (1) WO2008079685A2 (fr)
ZA (1) ZA200903598B (fr)

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CA2616943C (fr) 2005-07-29 2016-04-12 Solvay Pharmaceuticals Gmbh Procede de fabrication de poudre de pancreatine sterilisee
US9198871B2 (en) 2005-08-15 2015-12-01 Abbott Products Gmbh Delayed release pancreatin compositions
US11266607B2 (en) 2005-08-15 2022-03-08 AbbVie Pharmaceuticals GmbH Process for the manufacture and use of pancreatin micropellet cores
US10072256B2 (en) 2006-05-22 2018-09-11 Abbott Products Gmbh Process for separating and determining the viral load in a pancreatin sample
CA3081308C (fr) * 2006-12-21 2024-02-20 Novozymes A/S Variantes lipasiques pour une utilisation pharmaceutique
WO2009106553A2 (fr) * 2008-02-29 2009-09-03 Novozymes A/S Variante d’enzyme lipolytique à stabilité améliorée et polynucléotides codant pour cette variante
ES2429492T3 (es) 2008-02-29 2013-11-15 Dsm Ip Assets B.V. Lipasas con alta especificidad hacia ácidos grasos de cadena corta y usos de las mismas
EP2247721A2 (fr) * 2008-02-29 2010-11-10 The Procter & Gamble Company Composition détergente comprenant une lipase
US20140147895A1 (en) 2011-07-22 2014-05-29 Novozymes A/S Processes for Pretreating Cellulosic Material and Improving Hydrolysis Thereof
US8268305B1 (en) 2011-09-23 2012-09-18 Bio-Cat, Inc. Method and compositions to reduce serum levels of triacylglycerides in human beings using a fungal lipase
MX2014007612A (es) * 2011-12-29 2014-09-15 Novozymes As Composiciones detergentes con variantes de lipasa.
EP3211074B1 (fr) * 2012-02-03 2020-03-11 Novozymes A/S Variantes de la lipase et polynucléotides les codant
CN104204198B (zh) * 2012-04-02 2018-09-25 诺维信公司 脂肪酶变体以及编码其的多核苷酸
KR20150067336A (ko) * 2012-10-12 2015-06-17 다니스코 유에스 인크. 지방분해 효소 변이체를 포함하는 조성물 및 방법
BR112015028666B8 (pt) * 2013-05-14 2022-08-09 Novozymes As Composição detergente, método para produzir a mesma, método para a limpeza de um objeto e usos da composição
EP3022299B1 (fr) * 2013-07-19 2020-03-18 Danisco US Inc. Compositions et méthodes comprenant un variant d'enzyme lipolytique
WO2016079305A1 (fr) * 2014-11-20 2016-05-26 Novozymes A/S Variants de alicyclobacillus et polynucléotides codant pour ceux-ci
EP4067485A3 (fr) * 2014-12-05 2023-01-04 Novozymes A/S Variantes de la lipase et polynucléotides les codant
EP3230442B1 (fr) 2014-12-09 2019-05-22 Novozymes A/S Variantes de la lipase et polynucléotides les codant
CN107864658A (zh) 2015-04-07 2018-03-30 诺维信公司 用于选择具有脂肪酶活性的酶的方法
EP3317389B1 (fr) * 2015-07-03 2019-04-10 Novozymes A/S Compositions de detergents ayant une stabilite amelioree en presence de sulfites
JP7081767B2 (ja) * 2017-01-30 2022-06-07 学校法人日本医科大学 アデノ随伴ウイルス(aav)キャプシドタンパク質の変異体
CN111356762A (zh) * 2017-09-27 2020-06-30 诺维信公司 脂肪酶变体和包含此类脂肪酶变体的微囊组合物
EP3461892A3 (fr) * 2017-09-27 2019-06-12 The Procter & Gamble Company Compositions détergentes comprenant des lipases
WO2019154954A1 (fr) * 2018-02-08 2019-08-15 Novozymes A/S Variants de lipase et compositions en comprenant
CN111334369B (zh) * 2020-03-11 2022-10-21 陕西科技大学 一种酶法制备卵磷脂型pufa的方法
BR112023008326A2 (pt) * 2020-10-29 2023-12-12 Novozymes As Variantes de lipase e composições compreendendo tais variantes de lipase
CN113846074B (zh) * 2021-10-20 2022-10-21 南京林业大学 一种疏棉状嗜热丝孢菌脂肪酶突变体g91c及其应用
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BRPI0611932A2 (pt) 2005-06-24 2011-01-04 Novozymes As amilase, uso da mesma, composição farmacêutica, e, método para o tratamento de uma doença
WO2007080197A2 (fr) * 2006-01-16 2007-07-19 Novozymes A/S Enzymes immobilisees
CN101370921B (zh) * 2006-01-23 2014-08-13 宝洁公司 包含脂肪酶和漂白催化剂的组合物
EP1979477B1 (fr) * 2006-01-23 2017-04-19 Novozymes A/S Variantes de lipase
CA3081308C (fr) * 2006-12-21 2024-02-20 Novozymes A/S Variantes lipasiques pour une utilisation pharmaceutique

Also Published As

Publication number Publication date
EP2261328A1 (fr) 2010-12-15
AR064494A1 (es) 2009-04-08
EP2455461A3 (fr) 2013-05-29
EP2455461B1 (fr) 2016-03-16
IL198893A0 (en) 2010-02-17
CA3081308C (fr) 2024-02-20
CN101743308A (zh) 2010-06-16
JP2010512795A (ja) 2010-04-30
EP2261328B1 (fr) 2013-11-20
BRPI0721103A2 (pt) 2014-03-04
EP2455462B1 (fr) 2016-03-16
EP2455459A2 (fr) 2012-05-23
US9029115B2 (en) 2015-05-12
CN105112386A (zh) 2015-12-02
EP2455460A3 (fr) 2012-12-26
EP2455462A2 (fr) 2012-05-23
EP2455459A3 (fr) 2013-04-24
CA2670643A1 (fr) 2008-07-03
WO2008079685A3 (fr) 2008-11-06
EP2455462A3 (fr) 2013-05-29
JP5406040B2 (ja) 2014-02-05
MX2009006597A (es) 2009-07-02
US20120308543A1 (en) 2012-12-06
US8273348B2 (en) 2012-09-25
EP2099907A2 (fr) 2009-09-16
WO2008079685A2 (fr) 2008-07-03
CN101743308B (zh) 2015-09-16
EP2455461A2 (fr) 2012-05-23
KR20090101930A (ko) 2009-09-29
CA2961041C (fr) 2020-07-14
ZA200903598B (en) 2010-04-28
US9539311B2 (en) 2017-01-10
AU2007337150A1 (en) 2008-07-03
CA2961041A1 (fr) 2008-07-03
EP2455460A2 (fr) 2012-05-23
US20150209414A1 (en) 2015-07-30
CA2670643C (fr) 2017-04-25
US20100034797A1 (en) 2010-02-11
EP2455459B1 (fr) 2016-03-16
CA3081308A1 (fr) 2008-07-03
TW200829698A (en) 2008-07-16
RU2009128067A (ru) 2011-01-27

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